 3-Oxo-5-alpha-Steroid 4-Dehydrogenase
"3-Oxo-5-alpha-Steroid 4-Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the reduction of TESTOSTERONE to 5-ALPHA DIHYDROTESTOSTERONE.
| Descriptor ID |
D013741
|
| MeSH Number(s) |
D08.811.682.660.465
|
| Concept/Terms |
3-Oxo-5-alpha-Steroid 4-Dehydrogenase- 3-Oxo-5-alpha-Steroid 4-Dehydrogenase
- 3 Oxo 5 alpha Steroid 4 Dehydrogenase
- 4-Ene-3-Oxosteroid-5alpha-Reductase
- 4 Ene 3 Oxosteroid 5alpha Reductase
- 4-Ene-5-alpha-Reductase
- 4 Ene 5 alpha Reductase
- 5-alpha-Reductase, Testosterone
- 5 alpha Reductase, Testosterone
- delta(4)-3-Ketosteroid-5alpha-Reductase
- Testosterone delta-4-5-alpha-Reductase
- Testosterone delta 4 5 alpha Reductase
- delta-4-5-alpha-Reductase, Testosterone
- NADPH delta(4)-3-Ketosteroid 5 alpha-Oxidoreductase
- Steroid 5-alpha-Reductase
- 5-alpha-Reductase, Steroid
- Steroid 5 alpha Reductase
- Steroid 5Alpha Reductase
- 5Alpha Reductase, Steroid
- Reductase, Steroid 5Alpha
- Steroid delta-4-5-alpha Reductase
- Reductase, Steroid delta-4-5-alpha
- Steroid delta 4 5 alpha Reductase
- delta-4-5-alpha Reductase, Steroid
- Testosterone 5-alpha-Reductase
- Testosterone 5 alpha Reductase
- 3-Keto-5-alpha-Steroid delta-4-Dehydrogenase
- 3 Keto 5 alpha Steroid delta 4 Dehydrogenase
- delta-4-Dehydrogenase, 3-Keto-5-alpha-Steroid
- NADH-5-alpha-Reductase
- NADH 5 alpha Reductase
|
Below are MeSH descriptors whose meaning is more general than "3-Oxo-5-alpha-Steroid 4-Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "3-Oxo-5-alpha-Steroid 4-Dehydrogenase".
This graph shows the total number of publications written about "3-Oxo-5-alpha-Steroid 4-Dehydrogenase" by people in this website by year, and whether "3-Oxo-5-alpha-Steroid 4-Dehydrogenase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1986 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "3-Oxo-5-alpha-Steroid 4-Dehydrogenase" by people in Profiles.
-
Cantagrel V, Lefeber DJ, Ng BG, Guan Z, Silhavy JL, Bielas SL, Lehle L, Hombauer H, Adamowicz M, Swiezewska E, De Brouwer AP, Blümel P, Sykut-Cegielska J, Houliston S, Swistun D, Ali BR, Dobyns WB, Babovic-Vuksanovic D, van Bokhoven H, Wevers RA, Raetz CR, Freeze HH, Morava E, Al-Gazali L, Gleeson JG. SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder. Cell. 2010 Jul 23; 142(2):203-17.
-
Uemura M, Honma S, Chung S, Takata R, Furihata M, Nishimura K, Nonomura N, Nasu Y, Miki T, Shuin T, Fujioka T, Okuyama A, Nakamura Y, Nakagawa H. 5alphaDH-DOC (5alpha-dihydro-deoxycorticosterone) activates androgen receptor in castration-resistant prostate cancer. Cancer Sci. 2010 Aug; 101(8):1897-904.
-
Orvieto M, Eggener S. Editorial comment on: Pharmacological approaches to reducing the risk of prostate cancer. Eur Urol. 2009 May; 55(5):1073-4.
-
Uemura M, Tamura K, Chung S, Honma S, Okuyama A, Nakamura Y, Nakagawa H. Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer. Cancer Sci. 2008 Jan; 99(1):81-6.
-
Deplewski D, Liao S, Rosenfield RL. Preputial sebocyte 5alpha-reductase isoform specificity. Endocrinology. 1997 Oct; 138(10):4416-20.
-
Maudelonde T, Rosenfield RL, Shuler CF, Schwartz SA. Studies of androgen metabolism and action in cultured hair and skin cells. J Steroid Biochem. 1986 May; 24(5):1053-60.
-
Isaacs JT, Brendler CB, Walsh PC. Changes in the metabolism of dihydrotestosterone in the hyperplastic human prostate. J Clin Endocrinol Metab. 1983 Jan; 56(1):139-46.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|