"Tretinoin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).
| Descriptor ID |
D014212
|
| MeSH Number(s) |
D02.455.326.271.665.202.495.818.500 D02.455.426.392.368.367.379.249.700.860.500 D02.455.849.131.495.818.800 D23.767.261.700.780
|
| Concept/Terms |
Tretinoin- Tretinoin
- Retinoic Acid
- Acid, Retinoic
- Vitamin A Acid
- Acid, Vitamin A
- all-trans-Retinoic Acid
- Acid, all-trans-Retinoic
- all trans Retinoic Acid
- trans-Retinoic Acid
- Acid, trans-Retinoic
- trans Retinoic Acid
|
Below are MeSH descriptors whose meaning is more general than "Tretinoin".
Below are MeSH descriptors whose meaning is more specific than "Tretinoin".
This graph shows the total number of publications written about "Tretinoin" by people in this website by year, and whether "Tretinoin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1996 | 3 | 0 | 3 |
| 1997 | 1 | 1 | 2 |
| 1998 | 3 | 1 | 4 |
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 2 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 3 | 2 | 5 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 2 | 1 | 3 |
| 2007 | 0 | 3 | 3 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 3 | 4 |
| 2010 | 4 | 8 | 12 |
| 2011 | 1 | 2 | 3 |
| 2012 | 3 | 1 | 4 |
| 2013 | 1 | 1 | 2 |
| 2014 | 2 | 1 | 3 |
| 2015 | 3 | 2 | 5 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 2 | 3 |
| 2019 | 0 | 2 | 2 |
| 2020 | 3 | 2 | 5 |
| 2021 | 1 | 1 | 2 |
| 2024 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Tretinoin" by people in Profiles.
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Quantitative analysis of cis-regulatory elements in transcription with KAS-ATAC-seq. Nat Commun. 2024 Aug 10; 15(1):6852.
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All-trans retinoic acid overcomes solid tumor radioresistance by inducing inflammatory macrophages. Sci Immunol. 2021 06 15; 6(60).
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All-trans retinoic acid and protein kinase C a/ß1 inhibitor combined treatment targets cancer stem cells and impairs breast tumor progression. Sci Rep. 2021 03 15; 11(1):6044.
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A theoretical model of neural maturation in the developing chick spinal cord. PLoS One. 2020; 15(12):e0244219.
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Local retinoic acid signaling directs emergence of the extraocular muscle functional unit. PLoS Biol. 2020 11; 18(11):e3000902.
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The Cdx transcription factors and retinoic acid play parallel roles in antero-posterior position of the pectoral fin field during gastrulation. Mech Dev. 2020 12; 164:103644.
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Treatment of acute promyelocytic leukemia in older patients: recommendations of an International Society of Geriatric Oncology (SIOG) task force. J Geriatr Oncol. 2020 11; 11(8):1199-1209.
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Retinoic acid degradation shapes zonal development of vestibular organs and sensitivity to transient linear accelerations. Nat Commun. 2020 01 02; 11(1):63.
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Bone Marrow Findings in Patients With Acute Promyelocytic Leukemia Treated With Arsenic Trioxide. Am J Clin Pathol. 2019 10 07; 152(5):675-685.
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Interpreting Coronary Artery Disease Risk Through Gene-Environment Interactions in Gene Regulation. Genetics. 2019 10; 213(2):651-663.