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Tong-Chuan He

TitleAssociate Professor
InstitutionUniversity of Chicago
DepartmentOrthopedic Surgery and Rehabilitation Medicine
AddressChicago IL 60637
Phone+1 (773) 7027169
Email
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    Collapse Overview 
    Collapse overview
    I direct the Molecular Oncology Laboratory in the Department of Orthopaedic Surgery and Rehabilitation Medicine. Our lab consists of a dynamic group of basic science investigators and physician scientists, who have diverse expertise and a broad range of research interests. Our shared long-term objective is to better understand the molecular pathogenesis of bone and musculoskeletal diseases and to translate basic discoveries into potential therapies and/or preventive measures in clinical settings. Specifically, we focus on the following areas:

    LINEAGE COMMITMENT AND TERMINAL DIFFERENTIATION OF MESENCHYMAL STEM CELLS (MSCS)

    Multipotency of MSCs
    MSCs are pluripotent and capable of differentiating into osteogenic, chondrogenic, myogenic or adipogenic lineage. Understanding the molecular mechanisms of bone formation is pivotal for studying the pathogenesis of bone diseases. We are interested in elucidating the molecular mechanisms through which regulate the proliferation and differentiation of osteoblasts, chondrocytes, and adipocytes. Both Wnt/beta-catenin and bone morphogenetic proteins (BMPs) have been considered as important regulators of osteogenic differentiation of mesenchymal stem cells. We are investigating the biological functions of BMPs and Wnt/beta-catenin signaling in regulating the osteoblast differentiation of MSCs. We have therefore conducted a comprehensive analysis of BMP and Wnt3A-induced osteoblast differentiation of MSCs. Our findings indicate that osteoblast differentiation is a well-regulated process in normal progenitor cells, while osteosarcoma cells are refractory to osteogenic differentiation signal.

    BMP-9 is one of the most potent regulators of osteogenic differentiation
    The bone-forming osteoblasts are derived from pluripotent bone marrow fibroblasts (a.k.a., MSCs). Although the molecular mechanisms underlying bone formation remain to be defined, BMPs seem to play an important role in osteoblast differentiation. At least 15 types of BMPs have been identified in mice and humans. However, the ability of BMPs to induce osteoblast differentiation of mesenchymal stem cells has not been comprehensively investigated, mostly due to the fact that recombinant proteins are either not biologically active or not available for all BMPs. Through a comprehensive analysis, we found that BMP2, BMP6, and BMP9 (to a much lesser extent, BMP4 and BMP7) exhibited the greatest ability to induce osteoblast differentiation, whereas BMP3 was shown to inhibit osteogenesis, both in vitro and in vivo. Our findings about BMP9 as one of the most potent inducers of osteoblast differentiation are novel and particularly intriguing because BMP9 is one of the least characterized BMPs and its functions are largely unknown. Thus, many questions regarding BMP9 signaling need to be answered: What are the type I and type II TGFbeta/BMP receptors involved in BMP9 binding? What Smads are required for BMP9 signaling? How are the downstream targets regulated by BMP9? More importantly, what are the roles of BMP9 during embryonic and/or skeletal development? We are interested in addressing these questions.

    Critical mediators of BMP-induced differentiation of MSCs
    We have identified several potentially important signaling mediators of BMP-induced osteogenic differentiation. These targets include the Inhibitors of DNA binding/Differentiation helix-loop-helix (a.k.a., Id proteins) and CTGF. Interestingly, both Ids and CTGF have been shown to overexpress in human tumors. Our findings suggest that Ids and CTGF may play an important role in promoting the proliferation of early osteoblast progenitor cells and that their expression must be down-regulated during the terminal differentiation of committed osteoblasts, suggesting that a balanced regulation of their expression may be critical to BMP-induced osteoblast lineage-specific differentiation of MSCs. We are currently dissecting the functional roles of the important downstream mediators in BMP-induced osteogenic signaling. We are also interested in identifying the molecular switches that control the lineage-specific differentiation of osteoblasts, chondrocytes, and adipocytes in MSCs. We are especially interested in understanding at what stage osteogenic BMPs (e.g., BMP2 or BMP9)-induced osteogenic and adipogenic differentiation diverges. What are the potential regulators that control this lineage divergence? It has been long postulated that a disrupted balance between osteogenesis and adipogenesis may cause musculoskeletal diseases, such as osteoporosis.

    Wnts regulate osteogenic differentiation of mesenchymal stem cells
    Our earlier studies demonstrated that Wnt/beta-catenin signaling is de-regulated in over 70% of human osteosarcoma. Recent studies also suggest that Wnt signaling may play an important role in regulating bone density, and one of the Wnt signaling antagonists Dkk1 may be implicated in the development of osteolytic lesion in multiple myeloma patients. We demonstrated that Wnt3A can induce the early osteogenic marker alkaline phosphatase in MSCs. Upon analyzing the gene expression profile of MSCs that were stimulated with Wnt3A, we found that three members of the CCN family, CCN1/Cyr61, CCN2/CTGF, and CCN5/WISP2, were among the most significantly up-regulated genes. Further studies demonstrate that CTGF is a mutual target of Wnt and BMP-9, and plays an important role in regulating osteogenic differentiation. However, more questions remain to be answered. We are currently investigating how osteogenic differentiation of MSCs is regulated by canonical and non-canonical Wnt signaling.

    MOLECULAR BASES OF BONE AND SOFT TISSUE SARCOMAS

    Sarcomas represent a heterogeneous group of malignant mesenchymal tumors with numerous histologic subtypes and complex cytogenetic abnormalities. Unlike other common solid tumors, sarcomas are relatively uncommon and their molecular pathogenesis, in general, are poorly understood. We mainly focus on understanding the molecular biology of primary bone tumor (a.k.a., osteosarcoma, OS). Osteosarcoma is the most common primary malignancy of bone, and is among the most common non-hematological primary tumors of bone in both children and adults. The peak incidence occurs in the second decade. With preoperative chemotherapy, the five-year survival rate of patients with non-metastatic tumors has improved significantly to approximately 60-70%. However, cases with local recurrence and/or pulmonary metastasis are usually less sensitive, if not resistant, to conventional chemotherapies. Several cytogenetic studies suggest that certain chromosomal regions may be amplified, rearranged, or deleted in some, but not all, human osteosarcomas. Unfortunately, the low incidence of this disease and the absence of any familial predisposition have complicated efforts to identify osteosarcoma-associated genes. Thus, we are taking a comprehensive approach to elucidate the molecular mechanisms underlying the development of osteosarcoma.

    Wnt/beta-catenin signaling in the development of human osteosarcoma
    Aberrant activation of Wnt/beta-catenin signaling by inactivating APC tumor suppressor or oncogenic activation of beta-catenin plays an important role in colorectal tumorigenesis. Oncogenic activation of beta-catenin has also been reported in several types of human solid tumors. We found that beta-catenin signaling is de-regulated in about 70% of human osteosarcoma without beta-catenin mutations. As in many other types of non-colon cancer, little is known about how Wnt/beta-catenin signaling pathway is activated. Therefore, we are interested in elucidating the upstream regulatory mechanisms that may underline of the beta-catenin signaling pathway. We are also interested in investigating the possible pathogenic role of beta-catenin deregulation in bone and soft tissue tumors. Furthermore, we are investigating the potential roles of EF-hand calcium-binding S100 proteins in osteosarcoma progression and the development of pulmonary metastasis.

    Clinically relevant osteosarcoma animal model
    In order to investigate the pathogenesis of human osteosarcoma, there is a great need to develop a clinically relevant animal model. We have developed such an orthotopic animal model of osteosarcoma using several human osteosarcoma lines. This clinically relevant model of human osteosarcoma provides varying degrees of tumor growth at the primary site and of metastatic potential. Thus, this orthotopic model is being used as a valuable tool to investigate factors that promote or inhibit osteosarcoma growth and/or metastasis. For instance, we are now using this model to investigate the roles of genes that are known to promote cell proliferation and inhibit differentiation, and genes that potentially promote or inhibit cancer metastasis. This orthotopic model can also be used to test anti-tumor small molecules or other targeted therapies.

    Osteosarcoma is a differentiation disease
    We believe that understanding the molecular events behind normal osteoblast differentiation of MSCs may provide important clues to osteosarcoma development. Stem cell differentiation and tumorigenesis share some strikingly similar characteristics. Both normal stem cells and cancer stem cells have the ability to self-renew. Although stem cells are often the target of genetic events that are necessary or sufficient for malignant transformation, in some cases restricted progenitors or even differentiated cells may become transformed. Thus, cancer stem cells may be derived from tissue-specific stem cells or progenitors, such as MSCs. Although cancer stem cells for osteosarcoma remain to be identified, OS cells indeed exhibit the characteristics of undifferentiated osteoblasts, and we have shown that differentiation-promoting agents can inhibit OS proliferation. Accordingly, we found that human osteosarcoma cells are in general refractory to osteogenic BMPs and exhibit no signs of terminal differentiation upon osteogenic BMP stimulation. Thus, we hypothesize that osteosarcoma development is caused by molecular/genetic disruptions of the osteogenic differentiation pathway. We are investigating and identifying the possible defects in osteogenic pathway, including the possible roles of the early target genes of BMP-induced osteoblast lineage-specific differentiation of MSCs.

    MOLECULAR BIOLOGY OF CANCER METASTASIS

    Cancer metastasis is an often overlooked and least understood problem. Metastasis is defined as the progressive growth of tumor cells at a site that is discontinuous from the primary tumor. Although not an efficient process, colonization at distant tissues by tumor cells represents the most dangerous attribute of cancer, because metastases, rather than primary tumors, are responsible for most cancer deaths. Metastatic cells are a subset of primary tumor cells that have acquired the ability to complete a multi-step metastatic cascade, including migration, dissemination, extravasation, and eventual proliferation at a discontinuous secondary site. Understanding the molecular biology of cancer metastasis may provide novel intervention strategies to control/contain metastatic lesions, and/or to improve the quality of life for the patients with these advanced diseases.

    Pulmonary metastasis of primary bone tumors
    Lung metastasis is the leading cause of OS mortality. Our orthotopic tumor model of human OS provides a unique opportunity for us to investigate the molecular events underlying osteosarcoma pulmonary metastasis. Using this model, we have conducted serial selections of highly metastatic human OS sublines, which were otherwise non-metastatic. Using microarray analysis, we have compared the gene expression profiles between these sublines and the parental lines in search for gene(s) that may cause or be associated with osteosarcoma metastasis. In an alternative approach, we are conducting functional selection assays, in which an RNAi library has been introduced into the non-metastatic or less metastatic human osteosarcoma cells to recover lung metastases and to identify potential metastasis suppressors of human osteosarcoma.

    Metastatic bone tumors
    Bone is one of the most frequently targeted organs for cancer metastasis, and bone is the most common site for distant relapse of most cancers. The bone microenvironment is unique among metastatic target tissues because it is subjected to continuous remodeling under the influence circulating hormones and local bone-derived factors. Interactions between the bone microenvironment and the cancer cells can give rise to osteolytic (bone resorbing) or osteoblastic (bone forming) metastasis. Osteolytic bone metastasis are characteristic for most malignancies, such as breast cancer and lung cancer, while osteoblastic metastasis is mostly associated with prostate cancer. We are investigating the molecular mechanisms through which the interactions between metastatic (breast and prostate) cancer cells and bone microenvironment are regulated.

    NOVEL THERAPEUTIC AND/OR PREVENTIVE STRATEGIES FOR BONE AND MUSCULOSKELETAL DISEASES

    The ultimate goal of biomedical research is to develop innovative diagnostic, therapeutic, and/or preventive strategies for human diseases. We are interested in developing innovative approaches for local or systemic delivery of therapeutic genes as effective treatment for bone and musculoskeletal diseases. We are investigating the use of osteogenic BMPs for bone regeneration, enhancing fracture healing, repairing segmental defects, promoting spinal fusion, and preventing implant wear particle-induced osteolysis. We have recently demonstrated the potential use of some of the BMPs in promoting biomechanical features of healing tendons/ligaments. We also demonstrated that Sox9, a master regulator of chondrogenesis, may be used in gene therapy to treat intervertebral disc degeneration and articular cartilage injuries. These lines of investigation reflect our commitment to the true spirit of translational research in bone and musculoskeletal disorders.

    Collapse Biography 
    Collapse education and training
    Chongqing Medical University, Chongqing, ChinaB.M (MD equivalent)07/1984Medicine
    Chongqing Medical University, Chongqing, ChinaMSc07/1987Biochemistry
    The Pennsylvania State University, University Park, PAPhD12/1994Molecular Cell Biology
    HHMI/Johns Hopkins School of Medicine, Baltimore, MDPostdoc11/1999Cancer Biology/Genetics

    Collapse Research 
    Collapse research activities and funding
    R21CA226303     (HE, TONG-CHUAN)Apr 1, 2018 - Mar 31, 2021
    NIH
    A genomewide discovery of chemoresistance-associated noncoding RNAs in human cancers
    Role: Principal Investigator
    R01CA106569     (HE, TONG-CHUAN)Jan 26, 2006 - Dec 31, 2011
    NIH
    Regulation of beta-Catenin Signaling by Tyrosine Phosphorylation
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zhang S, Gao G, Zhou X, Du C, Zhu Y, He TC, Xu Y. Development of a novel rabbit model for femoroacetabular impingement through surgically induced acetabular overcoverage. J Orthop Res. 2024 Oct 13. PMID: 39396202.
      Citations:    Fields:    
    2. Zhu Y, Mei O, Zhang H, You W, Zhong J, Collins CP, Shen G, Luo C, Wu X, Li J, Shu Y, Wen Y, Luu HH, Shi LL, Fan J, He TC, Ameer GA, Sun C, Wen L, Reid RR. Establishment and characterization of a rat model of scalp-cranial composite defect for multilayered tissue engineering. Int J Surg. 2024 Oct 07. PMID: 39374047.
      Citations: 1     Fields:    
    3. Romanazzo S, Zhu Y, Sheikh R, Lin X, Liu H, He TC, Roohani I. Highly disordered and resorbable lithiated nanoparticles with osteogenic and angiogenic properties. J Mater Chem B. 2024 Oct 02; 12(38):9575-9591. PMID: 39210776.
      Citations:    Fields:    Translation:HumansAnimalsCells
    4. Parolia A, Eyunni S, Verma BK, Young E, Liu Y, Liu L, George J, Aras S, Das CK, Mannan R, Ur Rasool R, Mitchell-Velasquez E, Mahapatra S, Luo J, Carson SE, Xiao L, Gajjala PR, Venkatesh S, Jaber M, Wang X, He T, Qiao Y, Pang M, Zhang Y, Tien JC, Louw M, Alhusayan M, Cao X, Su F, Tavana O, Hou C, Wang Z, Ding K, Chinnaiyan AM, Asangani IA. NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis. Nat Genet. 2024 Oct; 56(10):2132-2143. PMID: 39251788; PMCID: PMC11525188.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    5. Kim M, Wang X, Li Y, Lin Z, Collins CP, Liu Y, Ahn Y, Tsal HM, Song JW, Duan C, Zhu Y, Sun C, He TC, Luo Y, Reid RR, Ameer GA. Personalized composite scaffolds for accelerated cell- and growth factor-free craniofacial bone regeneration. Bioact Mater. 2024 Nov; 41:427-439. PMID: 39188380; PMCID: PMC11345904.
      Citations:    
    6. Zhu Y, Mei O, Zhang H, You W, Zhong J, Collins CP, Shen G, Luo C, Wu X, Li J, Shu Y, Wen Y, Luu HH, Shi LL, Fan J, He TC, Ameer GA, Sun C, Wen L, Reid RR. Establishment and characterization of a rat model of scalp-cranial composite defect for multilayered tissue engineering. Res Sq. 2024 Jul 23. PMID: 39108474; PMCID: PMC11302684.
      Citations:    
    7. He T, Xiao L, Qiao Y, Klingbeil O, Young E, Wu XS, Mannan R, Mahapatra S, Redin E, Cho H, Bao Y, Kandarpa M, Ching-Yi Tien J, Wang X, Eyunni S, Zheng Y, Kim N, Zheng H, Hou S, Su F, Miner SJ, Mehra R, Cao X, Abbineni C, Samajdar S, Ramachandra M, Dhanasekaran SM, Talpaz M, Parolia A, Rudin CM, Vakoc CR, Chinnaiyan AM. Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies. Cancer Cell. 2024 Aug 12; 42(8):1336-1351.e9. PMID: 39029462.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    8. Choi JE, Qiao Y, Kryczek I, Yu J, Gurkan J, Bao Y, Gondal M, Tien JC, Maj T, Yazdani S, Parolia A, Xia H, Zhou J, Wei S, Grove S, Vatan L, Lin H, Li G, Zheng Y, Zhang Y, Cao X, Su F, Wang R, He T, Cieslik M, Green MD, Zou W, Chinnaiyan AM. PIKfyve controls dendritic cell function and tumor immunity. bioRxiv. 2024 Jul 01. PMID: 38464258; PMCID: PMC10925294.
      Citations:    
    9. Choi JE, Qiao Y, Kryczek I, Yu J, Gurkan J, Bao Y, Gondal M, Tien JC, Maj T, Yazdani S, Parolia A, Xia H, Zhou J, Wei S, Grove S, Vatan L, Lin H, Li G, Zheng Y, Zhang Y, Cao X, Su F, Wang R, He T, Cieslik M, Green MD, Zou W, Chinnaiyan AM. PIKfyve, expressed by CD11c-positive cells, controls tumor immunity. Nat Commun. 2024 Jun 28; 15(1):5487. PMID: 38942798; PMCID: PMC11213953.
      Citations:    Fields:    Translation:HumansAnimalsCells
    10. Ran S, Xue L, Wei X, Huang J, Yan X, He TC, Tang Z, Zhang H, Gu M. Recent advances in injectable hydrogel therapies for periodontitis. J Mater Chem B. 2024 Jun 27; 12(25):6005-6032. PMID: 38869470.
      Citations:    Fields:    Translation:HumansAnimals
    11. Zhao G, Zhao P, Wang Y, Zhang H, Zhu Y, Zhong J, You W, Shen G, Luo C, Mei O, Wu X, Li J, Shu Y, Wang H, Wagstaff W, Luu HH, Bi Y, Shi LL, Reid RR, He TC, Jiang L, Tang W, Fan J, Tang Z. GAPDH suppresses adenovirus-induced oxidative stress and enables a superfast production of recombinant adenovirus. Genes Dis. 2024 Nov; 11(6):101344. PMID: 39188753; PMCID: PMC11345542.
      Citations: 1     
    12. He T, Xiao L, Qiao Y, Klingbeil O, Young E, Wu XS, Mannan R, Mahapatra S, Eyunni S, Ching-Yi Tien J, Wang X, Zheng Y, Kim N, Zheng H, Hou S, Su F, Miner SJ, Mehra R, Cao X, Abbineni C, Samajdar S, Ramachandra M, Parolia A, Vakoc CR, Chinnaiyan AM. Targeting the mSWI/SNF Complex in POU2F-POU2AF Transcription Factor-Driven Malignancies. bioRxiv. 2024 May 24. PMID: 38328238; PMCID: PMC10849552.
      Citations:    
    13. Luo J, Chen Z, Qiao Y, Tien JC, Young E, Mannan R, Mahapatra S, He T, Eyunni S, Zhang Y, Zheng Y, Su F, Cao X, Wang R, Cheng Y, Seri R, George J, Shahine M, Miner SJ, Vaishampayan U, Wang M, Wang S, Parolia A, Chinnaiyan AM. p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer. bioRxiv. 2024 May 23. PMID: 38586029; PMCID: PMC10996709.
      Citations:    
    14. Tan S, Santolaya JL, Wright TF, Liu Q, Fujikawa T, Chi S, Bergstrom CP, Lopez A, Chen Q, Vale G, McDonald JG, Schmidt A, Vo N, Kim J, Baniasadi H, Li L, Zhu G, He TC, Zhan X, Obata Y, Jin A, Jia D, Elmquist JK, Sifuentes-Dominguez L, Burstein E. Interaction between the gut microbiota and colonic enteroendocrine cells regulates host metabolism. Nat Metab. 2024 Jun; 6(6):1076-1091. PMID: 38777856.
      Citations: 3     Fields:    Translation:AnimalsCells
    15. Liu L, Parolia A, Liu Y, Hou C, He T, Qiao Y, Eyunni S, Luo J, Li C, Wang Y, Zhou F, Huang W, Ren X, Wang Z, Chinnaiyan AM, Ding K. Discovery of LLC0424 as a Potent and Selective in Vivo NSD2 PROTAC Degrader. J Med Chem. 2024 May 09; 67(9):6938-6951. PMID: 38687638; PMCID: PMC11094793.
      Citations:    Fields:    Translation:HumansAnimalsCells
    16. Han T, Zhu T, Bian H, Chen J, Lu Y, Gu J, He TC, Qiao L, Zheng Q. Ddx5 participates in regulation of Col10a1 expression and chondrocyte hypertrophic differentiation in vitro. Am J Transl Res. 2024; 16(4):1454-1467. PMID: 38715834; PMCID: PMC11070370.
      Citations:    
    17. Han T, Zhu T, Lu Y, Wang Q, Bian H, Chen J, Qiao L, He TC, Zheng Q. Collagen type X expression and chondrocyte hypertrophic differentiation during OA and OS development. Am J Cancer Res. 2024; 14(4):1784-1801. PMID: 38726262; PMCID: PMC11076255.
      Citations:    
    18. Parolia A, Eyunni S, Verma BK, Young E, Liu L, George J, Aras S, Das CK, Mannan R, Rasool RU, Luo J, Carson SE, Mitchell-Velasquez E, Liu Y, Xiao L, Gajjala PR, Jaber M, Wang X, He T, Qiao Y, Pang M, Zhang Y, Alhusayan M, Cao X, Tavana O, Hou C, Wang Z, Ding K, Chinnaiyan AM, Asangani IA. NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis. bioRxiv. 2024 Mar 29. PMID: 38464251; PMCID: PMC10925163.
      Citations:    
    19. Cheng C, Hu J, Mannan R, Bhattacharyya R, Rossiter NJ, Magnuson B, Wisniewski JP, Zheng Y, Xiao L, Li C, Awad D, He T, Bao Y, Zhang Y, Cao X, Wang Z, Mehra R, Morlacchi P, Sahai V, di Magliano MP, Shah YM, Ding K, Qiao Y, Lyssiotis CA, Chinnaiyan AM. Targeting PIKfyve-driven lipid homeostasis as a metabolic vulnerability in pancreatic cancer. bioRxiv. 2024 Mar 20. PMID: 38562800; PMCID: PMC10983929.
      Citations:    
    20. Gou Y, Huang Y, Luo W, Li Y, Zhao P, Zhong J, Dong X, Guo M, Li A, Hao A, Zhao G, Wang Y, Zhu Y, Zhang H, Shi Y, Wagstaff W, Luu HH, Shi LL, Reid RR, He TC, Fan J. Adipose-derived mesenchymal stem cells (MSCs) are a superior cell source for bone tissue engineering. Bioact Mater. 2024 Apr; 34:51-63. PMID: 38186960; PMCID: PMC10770370.
      Citations: 10     
    21. Zhou Y, Deng Y, Wang J, Yan Z, Wei Q, Ye J, Zhang J, He TC, Qiao M. Effect of antibiotic monensin on cell proliferation and IGF1R signaling pathway in human colorectal cancer cells. Ann Med. 2023 12; 55(1):954-964. PMID: 36896461; PMCID: PMC10795625.
      Citations: 1     Fields:    Translation:HumansCells
    22. Bao Y, Qiao Y, Choi JE, Zhang Y, Mannan R, Cheng C, He T, Zheng Y, Yu J, Gondal M, Cruz G, Grove S, Cao X, Su F, Wang R, Chang Y, Kryczek I, Cieslik M, Green MD, Zou W, Chinnaiyan AM. Targeting the lipid kinase PIKfyve upregulates surface expression of MHC class I to augment cancer immunotherapy. Proc Natl Acad Sci U S A. 2023 Dec 05; 120(49):e2314416120. PMID: 38011559; PMCID: PMC10710078.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    23. Guo M, Gou Y, Dong X, Zhong J, Li A, Hao A, He TC, Fan J. Syrosingopine, an anti-hypertensive drug and lactate transporter (MCT1/4) inhibitor, activates hepatic stellate cells and exacerbates liver fibrosis in a mouse model. Genes Dis. 2024 Jul; 11(4):101169. PMID: 38434753; PMCID: PMC10909599.
      Citations: 3     
    24. Zhang Y, He TC, Zhang H. The impact of metabolic disorders on management of periodontal health in children. Pediatr Discov. 2024 Mar; 2(1). PMID: 38784180; PMCID: PMC11115384.
      Citations:    
    25. Qiang L, Zhao B, Ming M, Wang N, He TC, Hwang S, Thorburn A, He YY. Autophagy regulates tumor growth and metastasis. bioRxiv. 2023 Nov 03. PMID: 37961427; PMCID: PMC10635024.
      Citations:    
    26. Qi L, Li G, Li P, Wang H, Fang X, He T, Li J. Twenty years of Gendicine® rAd-p53 cancer gene therapy: The first-in-class human cancer gene therapy in the era of personalized oncology. Genes Dis. 2024 Jul; 11(4):101155. PMID: 38523676; PMCID: PMC10958704.
      Citations: 3     
    27. Zhou S, He TC, Zhang Y, Zhang H. Comparison of the main pathogenic microorganisms of various common oral diseases in children and adults. Pediatr Discov. 2023 Dec; 1(3). PMID: 38371743; PMCID: PMC10874635.
      Citations: 3     
    28. Wan Q, Tang M, Sun SL, Hu J, Sun ZJ, Fang YT, He TC, Zhang Y. Erratum: SNHG3 promotes migration, invasion, and epithelial-mesenchymal transition of breast cancer cells through the miR-186-5p/ZEB1 axis. Am J Transl Res. 2023; 15(9):5959-5960. PMID: 37854202; PMCID: PMC10579028.
      Citations:    
    29. Tian K, Gao G, He TC, Dong H, Zhang S, Zhang W, Wang J, Xu Y. Modified Technique for Labral Reconstruction of Hip Joint Using Autologous Iliotibial Band (ITB)-Make Labral Reconstruction Stress-Free. Arthrosc Tech. 2023 Sep; 12(9):e1615-e1622. PMID: 37780653; PMCID: PMC10533942.
      Citations:    
    30. Dong X, Gou Y, Guo M, Zhong J, Li A, Hao A, Zeng W, Haydon RC, Luu HH, Reid RR, He T, Xu Y, Fan J. A simplified noncryogenic strategy to transport mesenchymal stem cells: Potential applications in cell therapy and regenerative medicine. Genes Dis. 2024 May; 11(3):101073. PMID: 38274386; PMCID: PMC10808911.
      Citations: 3     
    31. Zhu D, Jiang T, Ma D, Zhang H, Zhang J, Lv W, Gong M, Wang H, Liu Z, Su H, Zeng L, Liu S, Tang S, Yang B, Tshavuka FI, Fu G, Liu Z, Peng D, Liu H, Yan Z, Cao Z, Zhao H, He TC, Yu J, Shu Y, Zou L. S1P-S1PR3-RAS promotes the progression of S1PR3hi TAL1+ T-cell acute lymphoblastic leukemia that can be effectively inhibited by an S1PR3 antagonist. Leukemia. 2023 10; 37(10):1982-1993. PMID: 37591940.
      Citations:    Fields:    Translation:HumansAnimalsCells
    32. Zhong J, Gou Y, Zhao P, Dong X, Guo M, Li A, Hao A, Luu HH, He TC, Reid RR, Fan J. Glycogen storage disease type I: Genetic etiology, clinical manifestations, and conventional and gene therapies. Pediatr Discov. 2023; 1(2). PMID: 38370424; PMCID: PMC10874634.
      Citations: 1     
    33. Yu M, Qin K, Fan J, Zhao G, Zhao P, Zeng W, Chen C, Wang A, Wang Y, Zhong J, Zhu Y, Wagstaff W, Haydon RC, Luu HH, Ho S, Lee MJ, Strelzow J, Reid RR, He TC. The evolving roles of Wnt signaling in stem cell proliferation and differentiation, the development of human diseases, and therapeutic opportunities. Genes Dis. 2024 May; 11(3):101026. PMID: 38292186; PMCID: PMC10825312.
      Citations: 12     
    34. Qiao Y, Wotring JW, Zheng Y, Zhang CJ, Zhang Y, Jiang X, Pretto CD, Eyunni S, Parolia A, He T, Cheng C, Cao X, Wang R, Su F, Ellison SJ, Wang Y, Qin J, Yan H, Zhou Q, Ma L, Sexton JZ, Chinnaiyan AM. Proxalutamide reduces SARS-CoV-2 infection and associated inflammatory response. Proc Natl Acad Sci U S A. 2023 07 25; 120(30):e2221809120. PMID: 37459541; PMCID: PMC10372636.
      Citations: 2     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    35. Zhong J, Tian L, Gou Y, Zhao P, Dong X, Guo M, Zhao G, Li A, Hao A, He TC, Fan J. BMP4 upregulates glycogen synthesis through the SMAD/SLC2A1 (GLUT1) signaling axis in hepatocellular carcinoma (HCC) cells. Cancer Metab. 2023 Jul 13; 11(1):9. PMID: 37443106; PMCID: PMC10339511.
      Citations: 3     
    36. Feng S, Xiao W, Zhang Y, Ma Y, Yang S, He T, Wang T. Effect of goal-directed fluid therapy based on both stroke volume variation and delta stroke volume on the incidence of composite postoperative complications among individuals undergoing meningioma resection. Chin Med J (Engl). 2023 08 20; 136(16):1990-1992. PMID: 37370235; PMCID: PMC10431378.
      Citations: 1     Fields:    Translation:Humans
    37. Wang X, Agrawal V, Dunton CL, Liu Y, Virk RKA, Patel PA, Carter L, Pujadas EM, Li Y, Jain S, Wang H, Ni N, Tsai HM, Rivera-Bolanos N, Frederick J, Roth E, Bleher R, Duan C, Ntziachristos P, He TC, Reid RR, Jiang B, Subramanian H, Backman V, Ameer GA. Chromatin reprogramming and bone regeneration in vitro and in vivo via the microtopography-induced constriction of cell nuclei. Nat Biomed Eng. 2023 Nov; 7(11):1514-1529. PMID: 37308586; PMCID: PMC10804399.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    38. Hu N, Jiang D, Huang E, Liu X, Li R, Liang X, Kim SH, Chen X, Gao JL, Zhang H, Zhang W, Kong YH, Zhang J, Wang J, Shui W, Luo X, Liu B, Cui J, Rose Rogers M, Shen J, Zhao C, Wang N, Wu N, Luu HH, Haydon RC, He TC, Huang W. Correction: BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells. J Cell Sci. 2023 Jun 01; 136(11). PMID: 37272422; PMCID: PMC11034876.
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    39. Hu J, Liao D, Sun Z, Ren W, Zhao L, Fang Y, Hu K, Yu H, Liu S, Zhou L, He T, Zhang Y. The HPV16 E6, E7/miR-23b-3p/ICAT signaling axis promotes proliferation, migration, invasion and EMT of cervical cancer cells. Carcinogenesis. 2023 05 27; 44(3):221-231. PMID: 36847693.
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    40. Cheng Q, Liu C, Chen Q, Luo W, He TC, Yang D. Establishing and characterizing human stem cells from the apical papilla immortalized by hTERT gene transfer. Front Cell Dev Biol. 2023; 11:1158936. PMID: 37283947; PMCID: PMC10239932.
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    41. Albaugh SL, Diaz A, Wang E, Shen TC, Williams L, He TC, Reid RR. Systematic Review of Nonsyndromic Craniosynostosis: Genomic Alterations and Impacted Signaling Pathways. Plast Reconstr Surg. 2024 02 01; 153(2):383e-396e. PMID: 37070824.
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    42. Rogers MR, Zeng W, Zhang X, Li R, Wei Q, Kong Y, Zhao P, Zhao G, Wang Y, Zhong J, Zhu Y, Haydon RC, Luu HH, Reid RR, Peterson DA, Lee MJ, He TC. Bone Morphogenic Protein 9 (BMP9)/Growth Differentiation Factor 2 (GDF2) modulates mouse adult hippocampal neurogenesis by regulating the survival of early neural progenitors. Genes Dis. 2023 Jul; 10(4):1175-1179. PMID: 37397531; PMCID: PMC10311160.
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    43. Li Y, Liu M, Cui J, Yang K, Zhao L, Gong M, Wang Y, He Y, He T, Bi Y. Erratum: [Corrigendum] Hepa1-6-FLuc cell line with the stable expression of firefly luciferase retains its primary properties with promising bioluminescence imaging ability. Oncol Lett. 2023 May; 25(5):187. PMID: 37065783; PMCID: PMC10091188.
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    44. Qin K, Yu M, Fan J, Wang H, Zhao P, Zhao G, Zeng W, Chen C, Wang Y, Wang A, Schwartz Z, Hong J, Song L, Wagstaff W, Haydon RC, Luu HH, Ho SH, Strelzow J, Reid RR, He TC, Shi LL. Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mechanisms and major signaling crosstalk. Genes Dis. 2024 Jan; 11(1):103-134. PMID: 37588235; PMCID: PMC10425814.
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    45. Liao J, Chen B, Zhu Z, Du C, Gao S, Zhao G, Zhao P, Wang Y, Wang A, Schwartz Z, Song L, Hong J, Wagstaff W, Haydon RC, Luu HH, Fan J, Reid RR, He TC, Shi L, Hu N, Huang W. Long noncoding RNA (lncRNA) H19: An essential developmental regulator with expanding roles in cancer, stem cell differentiation, and metabolic diseases. Genes Dis. 2023 Jul; 10(4):1351-1366. PMID: 37397543; PMCID: PMC10311118.
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    46. Yan S, Zhang R, Wu K, Cui J, Huang S, Ji X, An L, Yuan C, Gong C, Zhang L, Liu W, Feng Y, Zhang B, Dai Z, Shen Y, Wang X, Luo W, Liu B, Haydon RC, Lee MJ, Reid RR, Wolf JM, Shi Q, Luu HH, He TC, Weng Y. Corrigendum to "Characterization of the essential role of bone morphogenetic protein 9 (BMP9) in osteogenic differentiation of mesenchymal stem cells (MSCs) through RNA interference" [Genes & Diseases 5(2018):172-184]. Genes Dis. 2023 Mar; 10(2):632-637. PMID: 37223525; PMCID: PMC10201664.
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    47. Zhong J, Kang Q, Cao Y, He B, Zhao P, Gou Y, Luo Y, He TC, Fan J. Erratum: BMP4 augments the survival of hepatocellular carcinoma (HCC) cells under hypoxia and hypoglycemia conditions by promoting the glycolysis pathway. Am J Cancer Res. 2023; 13(3):1137-1139. PMID: 37034226; PMCID: PMC10077042.
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    48. Zhu Y, Shi Q, Peng Q, Gao Y, Yang T, Cheng Y, Wang H, Luo Y, Huang A, He TC, Fan J. [Corrigendum] A simplified 3D liver microsphere tissue culture model for hepatic cell signaling and drug-induced hepatotoxicity studies. Int J Mol Med. 2023 Apr; 51(4). PMID: 36896773; PMCID: PMC10035984.
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    49. Long noncoding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. J Cell Mol Med. 2023 Apr; 27(7):1021-1022. PMID: 36883309; PMCID: PMC10064026.
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    50. Wu R, Duan L, Ye L, Wang H, Yang X, Zhang Y, Chen X, Zhang Y, Weng Y, Luo J, Tang M, Shi Q, He T, Zhou L. [Corrigendum] S100A9 promotes the proliferation and invasion of HepG2 hepatocellular carcinoma cells via the activation of the MAPK signaling pathway. Int J Oncol. 2023 Apr; 62(4). PMID: 36866758; PMCID: PMC9990583.
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    51. Wu X, Li Z, Zhang H, He F, Qiao M, Luo H, Zhang J, Zhang M, Mao Y, Wagstaff W, Zhang Y, Niu C, Zhao X, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Haydon RC, Reid RR, Luu HH, He TC, Wang Z, Liang H, Zhang BQ, Wang N. Corrigendum to 'Modeling colorectal tumorigenesis using the organoids derived from conditionally immortalized mouse intestinal crypt cells (ciMICs)' [Genes Dis 8 (2021) 814-826]. Genes Dis. 2023 Mar; 10(2):618-619. PMID: 37223499; PMCID: PMC10201668.
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    52. Zhao C, Jiang W, Zhou N, Liao J, Yang M, Hu N, Liang X, Xu W, Chen H, Liu W, Shi LL, Oliveira L, Wolf JM, Ho S, Athiviraham A, Tsai HM, He TC, Huang W. Corrigendum to "Sox9 augments BMP2-induced chondrogenic differentiation by downregulating Smad7 in mesenchymal stem cells (MSCs)" [Genes & Diseases 4 (2017) 229-239]. Genes Dis. 2023 Mar; 10(2):624-626. PMID: 37223534; PMCID: PMC10201663.
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    53. Zeng Z, Huang B, Huang S, Zhang R, Yan S, Yu X, Shu Y, Zhao C, Lei J, Zhang W, Yang C, Wu K, Wu Y, An L, Ji X, Gong C, Yuan C, Zhang L, Liu W, Feng Y, Zhang B, Dai Z, Shen Y, Wang X, Luo W, Haydon RC, Luu HH, Zhou L, Reid RR, He TC, Wu X. Corrigendum to "The development of a sensitive fluorescent protein-based transcript reporter for high throughput screening of negative modulators of lncRNAs" [Genes & Diseases 5 (2018) 62-74]. Genes Dis. 2023 Mar; 10(2):627-629. PMID: 37223508; PMCID: PMC10201670.
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    54. Yu X, Chen L, Wu K, Yan S, Zhang R, Zhao C, Zeng Z, Shu Y, Huang S, Lei J, Ji X, Yuan C, Zhang L, Feng Y, Liu W, Huang B, Zhang B, Luo W, Wang X, Liu B, Haydon RC, Luu HH, He TC, Gan H. Corrigendum to "Establishment and functional characterization of the reversibly immortalized mouse glomerular podocytes (imPODs)" [Genes & Diseases 5 (2018) 137-149]. Genes Dis. 2023 Mar; 10(2):630-631. PMID: 37223498; PMCID: PMC10201652.
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    55. Li L, Dong Q, Wang Y, Feng Q, Zhou P, Ou X, Meng Q, He T, Luo J. [Retracted] Hedgehog signaling is involved in the BMP9-induced osteogenic differentiation of mesenchymal stem cells. Int J Mol Med. 2023 Apr; 51(4). PMID: 36825560; PMCID: PMC10049012.
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    56. Huang L, Zhang J, Deng Y, Wang H, Zhao P, Zhao G, Zeng W, Wang Y, Chen C, Wagstaff W, Haydon RC, Reid RR, He TC, Shen L, Luu HH, Zhao L. Niclosamide (NA) overcomes cisplatin resistance in human ovarian cancer. Genes Dis. 2023 Jul; 10(4):1687-1701. PMID: 37397523; PMCID: PMC10311098.
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    57. Zhang Y, Luo W, Zheng L, Hu J, Nie L, Zeng H, Tan X, Jiang Y, Li Y, Zhao T, Yang Z, He TC, Zhang H. Efficient bone regeneration of BMP9-stimulated human periodontal ligament stem cells (hPDLSCs) in decellularized bone matrix (DBM) constructs to model maxillofacial intrabony defect repair. Stem Cell Res Ther. 2022 12 27; 13(1):535. PMID: 36575551; PMCID: PMC9795631.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    58. Zhang HJ, Li FS, Wang F, Wang H, He TC, Reid RR, He BC, Xia Q. Transgenic PDGF-BB sericin hydrogel potentiates bone regeneration of BMP9-stimulated mesenchymal stem cells through a crosstalk of the Smad-STAT pathways. Regen Biomater. 2023; 10:rbac095. PMID: 36683747; PMCID: PMC9847547.
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    59. Yu Y, Zhong J, Chen C, Gou Y, Zhao G, Zhao P, Wang Y, Zeng W, Wang A, Wagstaff WD, Haydon RC, He TC, Reid RR, Lee MJ, Luu HH, Fan J. SV40 large T antigen-induced immortalization reprograms mouse cardiomyocyte progenitors with mesenchymal stem cell characteristics and osteogenic potential. Genes Dis. 2023 Jul; 10(4):1161-1164. PMID: 37397535; PMCID: PMC10311047.
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    60. Peng M, Ma X, Cao Y, Wang C, Tan Q, Chu X, Zhou P, Fu T, Liang P, Ran S, He TC, Wang J, Huang E. Comparison of the biomechanical differences in the occlusal movement of wild-type and BMP9 knockout mice with apical periodontitis. Front Bioeng Biotechnol. 2022; 10:1036061. PMID: 36324890; PMCID: PMC9618864.
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    61. Yu TX, Kalakonda S, Liu X, Han N, Chung HK, Xiao L, Rao JN, He TC, Raufman JP, Wang JY. Long noncoding RNA uc.230/CUG-binding protein 1 axis sustains intestinal epithelial homeostasis and response to tissue injury. JCI Insight. 2022 10 10; 7(19). PMID: 36214222; PMCID: PMC9675575.
      Citations: 7     Fields:    Translation:Animals
    62. Zhang L, Luo W, Liu J, Xu M, Peng Q, Zou W, You J, Shu Y, Zhao P, Wagstaff W, Zhao G, Qin K, Haydon RC, Luu HH, Reid RR, Bi Y, Zhao T, He TC, Fu Z. Modeling lung diseases using reversibly immortalized mouse pulmonary alveolar type 2 cells (imPAC2). Cell Biosci. 2022 Sep 22; 12(1):159. PMID: 36138472; PMCID: PMC9502644.
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    63. Schwartz Z, Zhao P, Wang A, Zhao G, Zeng W, Wang Y, Luu HH, Haydon RC, He TC, Reid RR, Strelzow J. Engineered nucleus-free mesenchymal stem cells (MSCs) for the targeted delivery of therapeutics to disease site. Genes Dis. 2023 Mar; 10(2):310-312. PMID: 37223510; PMCID: PMC10201659.
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    64. Fan J, Reid RR, He TC. Pyrvinium doubles against WNT-driven cancer. J Biol Chem. 2022 10; 298(10):102479. PMID: 36096200; PMCID: PMC9525899.
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    65. Luo W, Liang P, Zhao T, Cheng Q, Liu H, He L, Zhang L, Huang B, Zhang Y, He T, Yang D. Reversely immortalized mouse salivary gland cells presented a promising metabolic and fibrotic response upon BMP9/Gdf2 stimulation. Cell Mol Biol Lett. 2022 Jun 11; 27(1):46. PMID: 35690719; PMCID: PMC9188258.
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    66. Gardner BB, He TC, Wu S, Liu W, Gutierrez-Sherman V, Mass DP. Growth Factor Expression During Healing in 3 Distinct Tendons. J Hand Surg Glob Online. 2022 Jul; 4(4):214-219. PMID: 35880149; PMCID: PMC9308159.
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    67. Sun Y, He Y, Tong J, Liu D, Zhang H, He T, Bi Y. All-trans retinoic acid inhibits the malignant behaviors of hepatocarcinoma cells by regulating ferroptosis. Genes Dis. 2022 Nov; 9(6):1742-1756. PMID: 36157492; PMCID: PMC9485287.
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    68. Wagstaff W, Mwamba RN, Grullon K, Armstrong M, Zhao P, Hendren-Santiago B, Qin KH, Li AJ, Hu DA, Youssef A, Reid RR, Luu HH, Shen L, He TC, Haydon RC. Melanoma: Molecular genetics, metastasis, targeted therapies, immunotherapies, and therapeutic resistance. Genes Dis. 2022 Nov; 9(6):1608-1623. PMID: 36157497; PMCID: PMC9485270.
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    69. Gou Y, Weng Y, Chen Q, Wu J, Wang H, Zhong J, Bi Y, Cao D, Zhao P, Dong X, Guo M, Wagstaff W, Hendren-Santiago B, Chen C, Youssef A, Haydon RC, Luu HH, Reid RR, Shen L, He TC, Fan J. Carboxymethyl chitosan prolongs adenovirus-mediated expression of IL-10 and ameliorates hepatic fibrosis in a mouse model. Bioeng Transl Med. 2022 Sep; 7(3):e10306. PMID: 36176604; PMCID: PMC9472002.
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    70. He F, Ni N, Wang H, Zeng Z, Zhao P, Shi D, Xia Y, Chen C, Hu DA, Qin KH, Wagstaff W, Qin D, Hendren-Santiago B, Ho SH, Haydon RC, Luu HH, Reid RR, Shen L, Gan H, Fan J, He TC. OUHP: an optimized universal hairpin primer system for cost-effective and high-throughput RT-qPCR-based quantification of microRNA (miRNA) expression. Nucleic Acids Res. 2022 02 28; 50(4):e22. PMID: 34850128; PMCID: PMC8887422.
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    71. Eton D, Zhou G, He TC, Bartholomew A, Patil R. Filgrastim, fibrinolysis, and neovascularization. J Tissue Eng Regen Med. 2022 05; 16(5):496-510. PMID: 35175691; PMCID: PMC9302657.
      Citations: 3     Fields:    Translation:Humans
    72. Liu Q, Wang Z, Jiang Y, Shao F, Ma Y, Zhu M, Luo Q, Bi Y, Cao L, Peng L, Zhou J, Zhao Z, Deng X, He TC, Wang S. Single-cell landscape analysis reveals distinct regression trajectories and novel prognostic biomarkers in primary neuroblastoma. Genes Dis. 2022 Nov; 9(6):1624-1638. PMID: 36157484; PMCID: PMC9485279.
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    73. Sun Z, Hu J, Ren W, Fang Y, Hu K, Yu H, Liao D, Liu S, Zhou L, He T, Zhang Y. LncRNA SNHG3 regulates the BMSC osteogenic differentiation in bone metastasis of breast cancer by modulating the miR-1273g-3p/BMP3 axis. Biochem Biophys Res Commun. 2022 02 26; 594:117-123. PMID: 35081500.
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    74. Shi D, Mu S, Pu F, Liu J, Zhong B, Hu B, Ni N, Wang H, Luu HH, Haydon RC, Shen L, Zhang Z, He TC, Shao Z. Integrative analysis of immune-related multi-omics profiles identifies distinct prognosis and tumor microenvironment patterns in osteosarcoma. Mol Oncol. 2022 06; 16(11):2174-2194. PMID: 34894177; PMCID: PMC9168968.
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    75. Niu C, Wu D, Li AJ, Qin KH, Hu DA, Wang EJ, Tucker AB, He F, Huang L, Wang H, Liu Q, Ni N, Shi D, Zhao X, Wan Y, Li T, He T, Liao P. Identification of a prognostic signature based on copy number variations (CNVs) and CNV-modulated gene expression in acute myeloid leukemia. Am J Transl Res. 2021; 13(12):13683-13696. PMID: 35035707; PMCID: PMC8748127.
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    76. Ni N, Deng F, He F, Wang H, Shi D, Liao J, Zou Y, Wang H, Zhao P, Hu X, Chen C, Hu DA, Sabharwal M, Qin KH, Wagstaff W, Qin D, Hendren-Santiago B, Haydon RC, Luu HH, Reid RR, Shen L, He TC, Fan J. A one-step construction of adenovirus (OSCA) system using the Gibson DNA Assembly technology. Mol Ther Oncolytics. 2021 Dec 17; 23:602-611. PMID: 34977337; PMCID: PMC8666640.
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    77. Wang D, Kuzma ML, Tan X, He TC, Dong C, Liu Z, Yang J. Phototherapy and optical waveguides for the treatment of infection. Adv Drug Deliv Rev. 2021 12; 179:114036. PMID: 34740763; PMCID: PMC8665112.
      Citations: 9     Fields:    Translation:Humans
    78. Wang N, Zhang H, Zhang BQ, Liu W, Zhang Z, Qiao M, Zhang H, Deng F, Wu N, Chen X, Wen S, Zhang J, Liao Z, Zhang Q, Yan Z, Yin L, Ye J, Deng Y, Luu HH, Haydon RC, Liang H, He TC. Correction: Adenovirus-Mediated Efficient Gene Transfer into Cultured Three-Dimensional Organoids. PLoS One. 2021; 16(10):e0259544. PMID: 34710199; PMCID: PMC8553162.
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    79. Qiu D, Hu J, Hu J, Yu A, Othmane B, He T, Ding J, Cheng X, Ren W, Tan X, Yu Q, Chen J, Zu X. PMEPA1 Is a Prognostic Biomarker That Correlates With Cell Malignancy and the Tumor Microenvironment in Bladder Cancer. Front Immunol. 2021; 12:705086. PMID: 34777336; PMCID: PMC8582246.
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    80. Zhang N, Zhao L, Liu D, Hu C, Wang Y, He T, Bi Y, He Y. Characterization of Urine-Derived Stem Cells from Patients with End-Stage Liver Diseases and Application to Induced Acute and Chronic Liver Injury of Nude Mice Model. Stem Cells Dev. 2021 11; 30(22):1126-1138. PMID: 34549601.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    81. Cheng C, Qiu D, Chen J, Zu X, Liu J, Li H, Hu J, Yi Z, He T, Chen Z, Cui Y. Efficacy of Intra-Arterial Plus Intravesical Chemotherapy for High-Risk Non-Muscle-Invasive Bladder Cancer: A Pooled Analysis. Front Pharmacol. 2021; 12:707271. PMID: 34603020; PMCID: PMC8481664.
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    82. Zhong J, Wang H, Yang K, Wang H, Duan C, Ni N, An L, Luo Y, Zhao P, Gou Y, Sheng S, Shi D, Chen C, Wagstaff W, Hendren-Santiago B, Haydon RC, Luu HH, Reid RR, Ho SH, Ameer GA, Shen L, He TC, Fan J. Reversibly immortalized keratinocytes (iKera) facilitate re-epithelization and skin wound healing: Potential applications in cell-based skin tissue engineering. Bioact Mater. 2022 Mar; 9:523-540. PMID: 34820586; PMCID: PMC8581279.
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    83. Huang L, Zhao L, Zhang J, He F, Wang H, Liu Q, Shi D, Ni N, Wagstaff W, Chen C, Reid RR, Haydon RC, Luu HH, Shen L, He TC, Tang L. Antiparasitic mebendazole (MBZ) effectively overcomes cisplatin resistance in human ovarian cancer cells by inhibiting multiple cancer-associated signaling pathways. Aging (Albany NY). 2021 07 07; 13(13):17407-17427. PMID: 34232919; PMCID: PMC8312413.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    84. Shi D, Mu S, Pu F, Zhong B, Hu B, Liu J, He T, Zhang Z, Shao Z. Development of a Novel Immune Infiltration-Related ceRNA Network and Prognostic Model for Sarcoma. Front Cell Dev Biol. 2021; 9:652300. PMID: 34277600; PMCID: PMC8281254.
      Citations: 2     
    85. Pakvasa M, Tucker AB, Shen T, He TC, Reid RR. The Pleiotropic Intricacies of Hedgehog Signaling: From Craniofacial Patterning to Carcinogenesis. FACE (Thousand Oaks). 2021 Sep; 2(3):260-274. PMID: 35812774; PMCID: PMC9268505.
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    86. Zhao X, Huang B, Wang H, Ni N, He F, Liu Q, Shi D, Chen C, Zhao P, Wang X, Wagstaff W, Pakvasa M, Tucker AB, Lee MJ, Wolf JM, Reid RR, Hynes K, Strelzow J, Ho SH, Yu T, Yang J, Shen L, He TC, Zhang Y. A functional autophagy pathway is essential for BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs). Am J Transl Res. 2021; 13(5):4233-4250. PMID: 34150011; PMCID: PMC8205769.
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    87. Mao Y, Ni N, Huang L, Fan J, Wang H, He F, Liu Q, Shi D, Fu K, Pakvasa M, Wagstaff W, Tucker AB, Chen C, Reid RR, Haydon RC, Ho SH, Lee MJ, He TC, Yang J, Shen L, Cai L, Luu HH. Argonaute (AGO) proteins play an essential role in mediating BMP9-induced osteogenic signaling in mesenchymal stem cells (MSCs). Genes Dis. 2021 Nov; 8(6):918-930. PMID: 34522718; PMCID: PMC8427325.
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    88. Li RD, Deng ZL, Hu N, Liang X, Liu B, Luo J, Chen L, Yin L, Luo X, Shui W, He TC, Huang W. Erratum to: Biphasic effects of TGFß1 on BMP9-induced osteogenic differentiation of mesenchymal stem cells. BMB Rep. 2021 May; 54(5):284. PMID: 34042565; PMCID: PMC8167244.
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    89. Pei YA, Dong Y, He TC, Li WJ, Toh WS, Pei M. Editorial: Extracellular Vesicle Treatment, Epigenetic Modification and Cell Reprogramming to Promote Bone and Cartilage Regeneration. Front Bioeng Biotechnol. 2021; 9:678014. PMID: 33968918; PMCID: PMC8096898.
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    90. Hu C, He Y, Liu D, Zhao L, Fang S, Tan B, Dong S, Wang Y, He T, Bi Y. Hypoxia Preconditioning Promotes the Proliferation and Migration of Human Urine-Derived Stem Cells in Chronically Injured Liver of Mice by Upregulating CXCR4. Stem Cells Dev. 2021 05 15; 30(10):526-536. PMID: 33715421.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    91. Zhao X, Hu DA, Wu D, He F, Wang H, Huang L, Shi D, Liu Q, Ni N, Pakvasa M, Zhang Y, Fu K, Qin KH, Li AJ, Hagag O, Wang EJ, Sabharwal M, Wagstaff W, Reid RR, Lee MJ, Wolf JM, El Dafrawy M, Hynes K, Strelzow J, Ho SH, He TC, Athiviraham A. Applications of Biocompatible Scaffold Materials in Stem Cell-Based Cartilage Tissue Engineering. Front Bioeng Biotechnol. 2021; 9:603444. PMID: 33842441; PMCID: PMC8026885.
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    92. Hu C, He Y, Fang S, Tian N, Gong M, Xu X, Zhao L, Wang Y, He TC, Zhang Y, Bi Y. Erratum: Urine-derived stem cells accelerate the recovery of injured mouse hepatic tissue. Am J Transl Res. 2021; 13(3):1904. PMID: 33841718; PMCID: PMC8014404.
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    93. Zhong J, Kang Q, Cao Y, He B, Zhao P, Gou Y, Luo Y, He TC, Fan J. BMP4 augments the survival of hepatocellular carcinoma (HCC) cells under hypoxia and hypoglycemia conditions by promoting the glycolysis pathway. Am J Cancer Res. 2021; 11(3):793-811. PMID: 33791154; PMCID: PMC7994163.
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    94. Luo W, Zhang L, Huang B, Zhang H, Zhang Y, Zhang F, Liang P, Chen Q, Cheng Q, Tan D, Tan Y, Song J, Zhao T, Haydon RC, Reid RR, Luu HH, Lee MJ, El Dafrawy M, Ji P, He TC, Gou L. BMP9-initiated osteogenic/odontogenic differentiation of mouse tooth germ mesenchymal cells (TGMCS) requires Wnt/ß-catenin signalling activity. J Cell Mol Med. 2021 03; 25(5):2666-2678. PMID: 33605035; PMCID: PMC7933933.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    95. Wan Q, Tang M, Sun SL, Hu J, Sun ZJ, Fang YT, He TC, Zhang Y. SNHG3 promotes migration, invasion, and epithelial-mesenchymal transition of breast cancer cells through the miR-186-5p/ZEB1 axis. Am J Transl Res. 2021; 13(2):585-600. PMID: 33594311; PMCID: PMC7868844.
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    96. Yi Z, Ou Z, Guo X, Othmane B, Hu J, Ren W, Li H, He T, Qiu D, Cai Z, Chen J, Zu X. Recurrence factors in patients with Keratinizing squamous metaplasia of the bladder after surgical management: a single-center retrospective study. Transl Androl Urol. 2021 Feb; 10(2):734-740. PMID: 33718075; PMCID: PMC7947458.
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    97. Tao L, Fang SY, Zhao L, He TC, He Y, Bi Y. Indocyanine Green Uptake and Periodic Acid-Schiff Staining Method for Function Detection of Liver Cells are Affected by Different Cell Confluence. Cytotechnology. 2021 Apr; 73(2):159-167. PMID: 33927473; PMCID: PMC8035352.
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    98. Wu X, Li Z, Zhang H, He F, Qiao M, Luo H, Zhang J, Zhang M, Mao Y, Wagstaff W, Zhang Y, Niu C, Zhao X, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Haydon RC, Reid RR, Luu HH, He TC, Wang Z, Liang H, Zhang BQ, Wang N. Modeling colorectal tumorigenesis using the organoids derived from conditionally immortalized mouse intestinal crypt cells (ciMICs). Genes Dis. 2021 Nov; 8(6):814-826. PMID: 34522710; PMCID: PMC8427244.
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    99. Pu FF, Shi DY, Chen T, Liu YX, Zhong BL, Zhang ZC, Liu WJ, Wu Q, Wang BC, Shao ZW, He TC, Liu JX. SP1-induced long non-coding RNA SNHG6 facilitates the carcinogenesis of chondrosarcoma through inhibiting KLF6 by recruiting EZH2. Cell Death Dis. 2021 01 11; 12(1):59. PMID: 33431838; PMCID: PMC7801621.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    100. Li R, Zhang W, Yan Z, Liu W, Fan J, Feng Y, Zeng Z, Cao D, Haydon RC, Luu HH, Deng ZL, He TC, Zou Y. Long non-coding RNA (LncRNA) HOTAIR regulates BMP9-induced osteogenic differentiation by targeting the proliferation of mesenchymal stem cells (MSCs). Aging (Albany NY). 2021 01 10; 13(3):4199-4214. PMID: 33461171; PMCID: PMC7906180.
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    101. Li RF, Nan GX, Wang D, Gao C, Yang J, He TC, Zhang ZL. SV40T reprograms Schwann cells into stem-like cells that can re-differentiate into terminal nerve cells. Int J Dev Biol. 2021; 65(10-11-12):557-562. PMID: 34881802.
      Citations:    Fields:    Translation:Cells
    102. He T, Hu J, Qiu D, Deng H, Hu J, Chen J, Zu X. Smoking status and pathological response to neoadjuvant chemotherapy among patients with bladder cancer: a pooled analysis. Transl Androl Urol. 2021 Jan; 10(1):374-383. PMID: 33532325; PMCID: PMC7844483.
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    103. Dougherty U, Mustafi R, Zhu H, Zhu X, Deb D, Meredith SC, Ayaloglu-Butun F, Fletcher M, Sanchez A, Pekow J, Deng Z, Amini N, Konda VJ, Rao VL, Sakuraba A, Kwesi A, Kupfer SS, Fichera A, Joseph L, Hart J, He F, He TC, West-Szymanski D, Li YC, Bissonnette M. Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer. Epigenetics. 2021 12; 16(12):1317-1334. PMID: 33356812; PMCID: PMC8813074.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    104. Zhao L, Huang L, Zhang J, Fan J, He F, Zhao X, Wang H, Liu Q, Shi D, Ni N, Wagstaff W, Pakvasa M, Fu K, Tucker AB, Chen C, Reid RR, Haydon RC, Luu HH, Shen L, Qi H, He TC. The inhibition of BRAF activity sensitizes chemoresistant human ovarian cancer cells to paclitaxel-induced cytotoxicity and tumor growth inhibition. Am J Transl Res. 2020; 12(12):8084-8098. PMID: 33437383; PMCID: PMC7791515.
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    105. Zhang Y, Wu D, Zhao X, Pakvasa M, Tucker AB, Luo H, Qin KH, Hu DA, Wang EJ, Li AJ, Zhang M, Mao Y, Sabharwal M, He F, Niu C, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Chen C, Wagstaff W, Reid RR, Athiviraham A, Ho S, Lee MJ, Hynes K, Strelzow J, He TC, El Dafrawy M. Stem Cell-Friendly Scaffold Biomaterials: Applications for Bone Tissue Engineering and Regenerative Medicine. Front Bioeng Biotechnol. 2020; 8:598607. PMID: 33381499; PMCID: PMC7767872.
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    106. Pu F, Chen F, Zhang Z, Shi D, Zhong B, Lv X, Tucker AB, Fan J, Li AJ, Qin K, Hu D, Chen C, Wang H, He F, Ni N, Huang L, Liu Q, Wagstaff W, Luu HH, Haydon RC, Shen L, He TC, Liu J, Shao Z. Ferroptosis as a novel form of regulated cell death: Implications in the pathogenesis, oncometabolism and treatment of human cancer. Genes Dis. 2022 Mar; 9(2):347-357. PMID: 35224151; PMCID: PMC8843993.
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    107. Yi Z, Liu R, Hu J, He T, Wang Z, Li Y, Zu X. Clinicopathologic Features and Survival Outcomes for Primary Renal Neuroendocrine Neoplasms. Clin Genitourin Cancer. 2021 04; 19(2):155-161. PMID: 33288452.
      Citations: 5     Fields:    Translation:Humans
    108. Huang X, Chen Q, Luo W, Pakvasa M, Zhang Y, Zheng L, Li S, Yang Z, Zeng H, Liang F, Zhang F, Hu DA, Qin KH, Wang EJ, Qin DS, Reid RR, He TC, Athiviraham A, El Dafrawy M, Zhang H. SATB2: A versatile transcriptional regulator of craniofacial and skeleton development, neurogenesis and tumorigenesis, and its applications in regenerative medicine. Genes Dis. 2022 Jan; 9(1):95-107. PMID: 35005110; PMCID: PMC8720659.
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    109. Fang S, Hu C, Xu L, Cui J, Tao L, Gong M, Wang Y, He Y, He T, Bi Y. All-trans-retinoic acid inhibits the malignant behaviors of hepatocarcinoma cells by regulating autophagy. Am J Transl Res. 2020; 12(10):6793-6810. PMID: 33194073; PMCID: PMC7653590.
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    110. He F, Ni N, Zeng Z, Wu D, Feng Y, Li AJ, Luu B, Li AF, Qin K, Wang E, Wang X, Wu X, Luo H, Zhang J, Zhang M, Mao Y, Pakvasa M, Wagstaff W, Zhang Y, Niu C, Wang H, Huang L, Shi D, Liu Q, Zhao X, Fu K, Reid RR, Wolf JM, Lee MJ, Hynes K, Strelzow J, El Dafrawy M, Gan H, He TC, Fan J. FAMSi: A Synthetic Biology Approach to the Fast Assembly of Multiplex siRNAs for Silencing Gene Expression in Mammalian Cells. Mol Ther Nucleic Acids. 2020 Dec 04; 22:885-899. PMID: 33230483; PMCID: PMC7658575.
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    111. Cao D, Lei Y, Ye Z, Zhao L, Wang H, Zhang J, He F, Huang L, Shi D, Liu Q, Ni N, Pakvasa M, Wagstaff W, Zhao X, Fu K, Tucker AB, Chen C, Reid RR, Haydon RC, Luu HH, He TC, Liao Z. Blockade of IGF/IGF-1R signaling axis with soluble IGF-1R mutants suppresses the cell proliferation and tumor growth of human osteosarcoma. Am J Cancer Res. 2020; 10(10):3248-3266. PMID: 33163268; PMCID: PMC7642656.
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    112. Qiu D, Hu J, He T, Li H, Hu J, Yi Z, Chen J, Zu X. Effect of neoadjuvant chemotherapy on locally advanced upper tract urothelial carcinoma: a pooled analysis. Transl Androl Urol. 2020 Oct; 9(5):2094-2106. PMID: 33209672; PMCID: PMC7658168.
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    113. Hu C, He Y, Fang S, Tian N, Gong M, Xu X, Zhao L, Wang Y, He T, Zhang Y, Bi Y. Urine-derived stem cells accelerate the recovery of injured mouse hepatic tissue. Am J Transl Res. 2020; 12(9):5131-5150. PMID: 33042410; PMCID: PMC7540109.
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    114. Sawadogo WR, Luo Y, Elkington B, He TC, Wang CZ, Yuan CS. Cytotoxicity and Preliminary Analysis of the Pro-apoptotic and Cell Cycle Arrest Effects of Lantana ukambensis Against Colorectal Cancer Cells. Int J Appl Biol Pharm. 2020; 11(3):170-187. PMID: 32913383; PMCID: PMC7480948.
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    115. Cheng Q, Lin J, Chen Q, Zheng L, Tang Y, Wang F, Huang X, Zhang Y, Li S, Yang Z, Zhou P, He TC, Luo W, Zhang H. Role of Special AT-Rich Sequence-Binding Protein 2 in the Osteogenesis of Human Dental Mesenchymal Stem Cells. Stem Cells Dev. 2020 08; 29(16):1059-1072. PMID: 32484035.
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    116. Wang X, Zhao L, Wu X, Luo H, Wu D, Zhang M, Zhang J, Pakvasa M, Wagstaff W, He F, Mao Y, Zhang Y, Niu C, Wu M, Zhao X, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Hynes K, Strelzow J, El Dafrawy M, He TC, Qi H, Zeng Z. Development of a simplified and inexpensive RNA depletion method for plasmid DNA purification using size selection magnetic beads (SSMBs). Genes Dis. 2021 May; 8(3):298-306. PMID: 33997177; PMCID: PMC8093646.
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    117. Liao J, Xiao H, Dai G, He T, Huang W. Recombinant adenovirus (AdEasy system) mediated exogenous expression of long non-coding RNA H19 (lncRNA H19) biphasic regulating osteogenic differentiation of mesenchymal stem cells (MSCs). Am J Transl Res. 2020; 12(5):1700-1713. PMID: 32509170; PMCID: PMC7269984.
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    118. Hu J, Li H, He T, Deng H, Gong G, Cui Y, Liu P, Ren W, Li C, Chen J, Zu X. A nomogram incorporating PD-L1, NLR, and clinicopathologic features to predict inguinal lymph node metastasis in penile squamous cell carcinoma. Urol Oncol. 2020 07; 38(7):641.e19-641.e29. PMID: 32389428.
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    119. Hoffman RD, Li CY, He K, Wu X, He BC, He TC, Gao JL. Chinese Herbal Medicine and Its Regulatory Effects on Tumor Related T Cells. Front Pharmacol. 2020; 11:492. PMID: 32372963; PMCID: PMC7186375.
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    120. Pakvasa M, Haravu P, Boachie-Mensah M, Jones A, Coalson E, Liao J, Zeng Z, Wu D, Qin K, Wu X, Luo H, Zhang J, Zhang M, He F, Mao Y, Zhang Y, Niu C, Wu M, Zhao X, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Lee MJ, Wolf JM, Athiviraham A, Ho SS, He TC, Hynes K, Strelzow J, El Dafrawy M, Reid RR. Notch signaling: Its essential roles in bone and craniofacial development. Genes Dis. 2021 Jan; 8(1):8-24. PMID: 33569510; PMCID: PMC7859553.
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    121. Hu J, Chen J, Li H, He T, Deng H, Gong G, Cui Y, Liu P, Ren W, Zhou X, Li C, Zu X. A preoperative nomogram predicting the pseudocapsule status in localized renal cell carcinoma. Transl Androl Urol. 2020 Apr; 9(2):462-472. PMID: 32420152; PMCID: PMC7214989.
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    122. Zhang B, Yang L, Zeng Z, Feng Y, Wang X, Wu X, Luo H, Zhang J, Zhang M, Pakvasa M, Wagstaff W, He F, Mao Y, Qin K, Ding H, Zhang Y, Niu C, Wu M, Zhao X, Wang H, Huang L, Shi D, Liu Q, Ni N, Fu K, Athiviraham A, Moriatis Wolf J, Lee MJ, Hynes K, Strelzow J, El Dafrawy M, Xia Y, He TC. Leptin Potentiates BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells Through the Activation of JAK/STAT Signaling. Stem Cells Dev. 2020 04 15; 29(8):498-510. PMID: 32041483; PMCID: PMC7153647.
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    123. Song D, Huang S, Zhang L, Liu W, Huang B, Feng Y, Liu B, He TC, Huang D, Reid RR. Differential Responsiveness to BMP9 between Patent and Fused Suture Progenitor Cells from Craniosynostosis Patients. Plast Reconstr Surg. 2020 03; 145(3):552e-562e. PMID: 32097313.
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    124. Peng Q, Chen B, Wang H, Zhu Y, Wu J, Luo Y, Zu G, Luo J, Zhou L, Shi Q, Weng Y, Huang A, He TC, Fan J. Correction for: Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes. Aging (Albany NY). 2020 01 13; 12(2):2018-2021. PMID: 32028267; PMCID: PMC7053634.
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    125. Zeng Z, Huang B, Wang X, Fan J, Zhang B, Yang L, Feng Y, Wu X, Luo H, Zhang J, Zhang M, He F, Mao Y, Pakvasa M, Wagstaff W, Li AJ, Liu B, Ding H, Zhang Y, Niu C, Wu M, Zhao X, Wolf JM, Lee MJ, Huang A, Luu HH, Haydon RC, He TC. A reverse transcriptase-mediated ribosomal RNA depletion (RTR2D) strategy for the cost-effective construction of RNA sequencing libraries. J Adv Res. 2020 Jul; 24:239-250. PMID: 32373357; PMCID: PMC7195496.
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    126. Song D, Huang S, Zhang L, Liu W, Huang B, Feng Y, Liu B, He TC, Huang D, Reid RR. "Differential responsiveness to BMP9 between patent and fused suture progenitor cells from craniosynostosis patients." Plast Reconstr Surg. 2019 Dec 17. PMID: 31860505.
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    127. Peng Q, Chen B, Wang H, Zhu Y, Wu J, Luo Y, Zuo G, Luo J, Zhou L, Shi Q, Weng Y, Huang A, He TC, Fan J. Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes. Aging (Albany NY). 2019 12 12; 11(23):11520-11540. PMID: 31831718; PMCID: PMC6932923.
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    128. Zhang Z, Liu J, Zeng Z, Fan J, Huang S, Zhang L, Zhang B, Wang X, Feng Y, Ye Z, Zhao L, Cao D, Yang L, Pakvasa M, Liu B, Wagstaff W, Wu X, Luo H, Zhang J, Zhang M, He F, Mao Y, Ding H, Zhang Y, Niu C, Haydon RC, Luu HH, Lee MJ, Wolf JM, Shao Z, He TC. lncRNA Rmst acts as an important mediator of BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) by antagonizing Notch-targeting microRNAs. Aging (Albany NY). 2019 12 11; 11(24):12476-12496. PMID: 31825894; PMCID: PMC6949095.
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    129. Shu Y, Wang Y, Lv WQ, Peng DY, Li J, Zhang H, Jiang GJ, Yang BJ, Liu S, Zhang J, Chen YH, Tang S, Wan KX, Yuan JT, Guo W, Fu G, Qi XK, Liu ZD, Liu HY, Yang C, Zhang LH, Liu FJ, Yu J, Zhang PH, Qu B, Zhao H, He TC, Zou L. ARRB1-Promoted NOTCH1 Degradation Is Suppressed by OncomiR miR-223 in T-cell Acute Lymphoblastic Leukemia. Cancer Res. 2020 03 01; 80(5):988-998. PMID: 31822496; PMCID: PMC7056567.
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    130. Wang H, Cao Y, Shu L, Zhu Y, Peng Q, Ran L, Wu J, Luo Y, Zuo G, Luo J, Zhou L, Shi Q, Weng Y, Huang A, He TC, Fan J. Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. J Cell Mol Med. 2020 01; 24(2):1399-1412. PMID: 31809000; PMCID: PMC6991647.
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    131. Alverdy AK, Pakvasa M, Zhao C, Mostafa S, Liu W, Luo W, Wolf JM, Ameer GA, He TC, Reid RR. Imiquimod Acts Synergistically with BMP9 through the Notch Pathway as an Osteoinductive Agent In Vitro. Plast Reconstr Surg. 2019 11; 144(5):1094-1103. PMID: 31385892.
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    132. Liu B, Xin W, Tan JR, Zhu RP, Li T, Wang D, Kan SS, Xiong DK, Li HH, Zhang MM, Sun HH, Wagstaff W, Zhou C, Wang ZJ, Zhang YG, He TC. Myelin sheath structure and regeneration in peripheral nerve injury repair. Proc Natl Acad Sci U S A. 2019 10 29; 116(44):22347-22352. PMID: 31611410; PMCID: PMC6825268.
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    133. Coalson E, Bishop E, Liu W, Feng Y, Spezia M, Liu B, Shen Y, Wu D, Du S, Li AJ, Ye Z, Zhao L, Cao D, Li A, Hagag O, Deng A, Liu W, Li M, Haydon RC, Shi L, Athiviraham A, Lee MJ, Wolf JM, Ameer GA, He TC, Reid RR. Stem cell therapy for chronic skin wounds in the era of personalized medicine: From bench to bedside. Genes Dis. 2019 Dec; 6(4):342-358. PMID: 31832514; PMCID: PMC6888708.
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    134. Liu W, Deng Z, Zeng Z, Fan J, Feng Y, Wang X, Cao D, Zhang B, Yang L, Liu B, Pakvasa M, Wagstaff W, Wu X, Luo H, Zhang J, Zhang M, He F, Mao Y, Ding H, Zhang Y, Niu C, Haydon RC, Luu HH, Wolf JM, Lee MJ, Huang W, He TC, Zou Y. Highly expressed BMP9/GDF2 in postnatal mouse liver and lungs may account for its pleiotropic effects on stem cell differentiation, angiogenesis, tumor growth and metabolism. Genes Dis. 2020 Jun; 7(2):235-244. PMID: 32215293; PMCID: PMC7083737.
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    135. Wang X, Yuan C, Huang B, Fan J, Feng Y, Li AJ, Zhang B, Lei Y, Ye Z, Zhao L, Cao D, Yang L, Wu D, Chen X, Liu B, Wagstaff W, He F, Wu X, Luo H, Zhang J, Zhang M, Haydon RC, Luu HH, Lee MJ, Moriatis Wolf J, Huang A, He TC, Zeng Z. Developing a Versatile Shotgun Cloning Strategy for Single-Vector-Based Multiplex Expression of Short Interfering RNAs (siRNAs) in Mammalian Cells. ACS Synth Biol. 2019 09 20; 8(9):2092-2105. PMID: 31465214; PMCID: PMC6760290.
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    136. Lee CS, Bishop ES, Dumanian Z, Zhao C, Song D, Zhang F, Zhu Y, Ameer GA, He TC, Reid RR. Bone Morphogenetic Protein-9-Stimulated Adipocyte-Derived Mesenchymal Progenitors Entrapped in a Thermoresponsive Nanocomposite Scaffold Facilitate Cranial Defect Repair. J Craniofac Surg. 2019 Sep; 30(6):1915-1919. PMID: 30896511; PMCID: PMC6746609.
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    137. Zhu Y, Shi Q, Peng Q, Gao Y, Yang T, Cheng Y, Wang H, Luo Y, Huang A, He TC, Fan J. A simplified 3D liver microsphere tissue culture model for hepatic cell signaling and drug-induced hepatotoxicity studies. Int J Mol Med. 2019 Nov; 44(5):1653-1666. PMID: 31485603; PMCID: PMC6777685.
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    138. Mostafa S, Pakvasa M, Coalson E, Zhu A, Alverdy A, Castillo H, Fan J, Li A, Feng Y, Wu D, Bishop E, Du S, Spezia M, Li A, Hagag O, Deng A, Liu W, Li M, Ho SS, Athiviraham A, Lee MJ, Wolf JM, Ameer GA, Luu HH, Haydon RC, Strelzow J, Hynes K, He TC, Reid RR. The wonders of BMP9: From mesenchymal stem cell differentiation, angiogenesis, neurogenesis, tumorigenesis, and metabolism to regenerative medicine. Genes Dis. 2019 Sep; 6(3):201-223. PMID: 32042861; PMCID: PMC6997590.
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    139. Tan J, Xiong B, Zhu Y, Yao Y, Qian J, Rong S, Yang G, Zhu Q, Jiang Y, Zhou Q, Liu D, Deng C, Ran H, Wang Z, He T, Huang J. Carotid body enlargement in hypertension and other comorbidities evaluated by ultrasonography. J Hypertens. 2019 07; 37(7):1455-1462. PMID: 30925145.
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    141. Ren X, Zhou Q, Foulad D, Tiffany AS, Dewey MJ, Bischoff D, Miller TA, Reid RR, He TC, Yamaguchi DT, Harley BAC, Lee JC. Osteoprotegerin reduces osteoclast resorption activity without affecting osteogenesis on nanoparticulate mineralized collagen scaffolds. Sci Adv. 2019 06; 5(6):eaaw4991. PMID: 31206025; PMCID: PMC6561746.
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    142. Zhang L, Luo Q, Shu Y, Zeng Z, Huang B, Feng Y, Zhang B, Wang X, Lei Y, Ye Z, Zhao L, Cao D, Yang L, Chen X, Liu B, Wagstaff W, Reid RR, Luu HH, Haydon RC, Lee MJ, Wolf JM, Fu Z, He TC, Kang Q. Transcriptomic landscape regulated by the 14 types of bone morphogenetic proteins (BMPs) in lineage commitment and differentiation of mesenchymal stem cells (MSCs). Genes Dis. 2019 Sep; 6(3):258-275. PMID: 32042865; PMCID: PMC6997588.
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    143. Huang B, Huang LF, Zhao L, Zeng Z, Wang X, Cao D, Yang L, Ye Z, Chen X, Liu B, He TC, Wang X. Microvesicles (MIVs) secreted from adipose-derived stem cells (ADSCs) contain multiple microRNAs and promote the migration and invasion of endothelial cells. Genes Dis. 2020 Jun; 7(2):225-234. PMID: 32215292; PMCID: PMC7083715.
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    144. Huang X, Wang F, Zhao C, Yang S, Cheng Q, Tang Y, Zhang F, Zhang Y, Luo W, Wang C, Zhou P, Kim S, Zuo G, Hu N, Li R, He TC, Zhang H. Dentinogenesis and Tooth-Alveolar Bone Complex Defects in BMP9/GDF2 Knockout Mice. Stem Cells Dev. 2019 05 15; 28(10):683-694. PMID: 30816068; PMCID: PMC6534167.
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    145. Cen C, Wu J, Zhang Y, Luo C, Xie L, Zhang X, Yang X, Li M, Bi Y, Li T, He T. Improving Magnetofection of Magnetic Polyethylenimine Nanoparticles into MG-63 Osteoblasts Using a Novel Uniform Magnetic Field. Nanoscale Res Lett. 2019 Mar 12; 14(1):90. PMID: 30874913; PMCID: PMC6419855.
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    146. Zhao C, Qazvini NT, Sadati M, Zeng Z, Huang S, De La Lastra AL, Zhang L, Feng Y, Liu W, Huang B, Zhang B, Dai Z, Shen Y, Wang X, Luo W, Liu B, Lei Y, Ye Z, Zhao L, Cao D, Yang L, Chen X, Athiviraham A, Lee MJ, Wolf JM, Reid RR, Tirrell M, Huang W, de Pablo JJ, He TC. A pH-Triggered, Self-Assembled, and Bioprintable Hybrid Hydrogel Scaffold for Mesenchymal Stem Cell Based Bone Tissue Engineering. ACS Appl Mater Interfaces. 2019 Mar 06; 11(9):8749-8762. PMID: 30734555; PMCID: PMC6407040.
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    147. Wang X, Wu X, Zhang Z, Ma C, Wu T, Tang S, Zeng Z, Huang S, Gong C, Yuan C, Zhang L, Feng Y, Huang B, Liu W, Zhang B, Shen Y, Luo W, Wang X, Liu B, Lei Y, Ye Z, Zhao L, Cao D, Yang L, Chen X, Haydon RC, Luu HH, Peng B, Liu X, He TC. Monensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway. Sci Rep. 2018 12 17; 8(1):17914. PMID: 30559409; PMCID: PMC6297164.
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    148. Cui J, Zhang W, Huang E, Wang J, Liao J, Li R, Yu X, Zhao C, Zeng Z, Shu Y, Zhang R, Yan S, Lei J, Yang C, Wu K, Wu Y, Huang S, Ji X, Li A, Gong C, Yuan C, Zhang L, Liu W, Huang B, Feng Y, An L, Zhang B, Dai Z, Shen Y, Luo W, Wang X, Huang A, Luu HH, Reid RR, Wolf JM, Thinakaran G, Lee MJ, He TC. BMP9-induced osteoblastic differentiation requires functional Notch signaling in mesenchymal stem cells. Lab Invest. 2019 01; 99(1):58-71. PMID: 30353129; PMCID: PMC6300564.
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    149. Shu Y, Wu K, Zeng Z, Huang S, Ji X, Yuan C, Zhang L, Liu W, Huang B, Feng Y, Zhang B, Dai Z, Shen Y, Luo W, Wang X, Liu B, Lei Y, Ye Z, Zhao L, Cao D, Yang L, Chen X, Luu HH, Reid RR, Wolf JM, Lee MJ, He TC. A Simplified System to Express Circularized Inhibitors of miRNA for Stable and Potent Suppression of miRNA Functions. Mol Ther Nucleic Acids. 2018 Dec 07; 13:556-567. PMID: 30414569; PMCID: PMC6226557.
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    150. Wang Y, Li Y, Zou J, Polster SP, Lightle R, Moore T, Dimaano M, He TC, Weber CR, Awad IA, Shen L. The cerebral cavernous malformation disease causing gene KRIT1 participates in intestinal epithelial barrier maintenance and regulation. FASEB J. 2019 02; 33(2):2132-2143. PMID: 30252535; PMCID: PMC6338648.
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    151. Sheng W, Zhang ZC, Shi DY, Wang BC, Wu Q, Shao ZW, Yang SH, He TC, Liu JX. Epigenetic silencing of SFRP5 promotes the metastasis and invasion of chondrosarcoma by expression inhibition and Wnt signaling pathway activation. Chem Biol Interact. 2018 Dec 25; 296:1-8. PMID: 30125549.
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    152. Shu Y, Yang C, Ji X, Zhang L, Bi Y, Yang K, Gong M, Liu X, Guo Q, Su Y, Qu X, Nan G, Zhao C, Zeng Z, Yu X, Zhang R, Yan S, Lei J, Wu K, Wu Y, An L, Huang S, Gong C, Yuan C, Liu W, Huang B, Feng Y, Zhang B, Dai Z, Shen Y, Luo W, Wang X, Haydon RC, Luu HH, Reid RR, Wolf JM, Lee MJ, He TC, Li Y. Reversibly immortalized human umbilical cord-derived mesenchymal stem cells (UC-MSCs) are responsive to BMP9-induced osteogenic and adipogenic differentiation. J Cell Biochem. 2018 11; 119(11):8872-8886. PMID: 30076626; PMCID: PMC6195452.
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    153. Fang SY, Hu CQ, Liu MN, Tao L, Wang Y, Gong MJ, He Y, He TC, Bi Y. Reversibly immortalized hepatic progenitor cell line containing double suicide genes. Int J Mol Med. 2018 Oct; 42(4):1977-1986. PMID: 30085335; PMCID: PMC6108856.
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    154. Luo C, Yang X, Li M, Huang H, Kang Q, Zhang X, Hui H, Zhang X, Cen C, Luo Y, Xie L, Wang C, He T, Jiang D, Li T, An H. A novel strategy for in vivo angiogenesis and osteogenesis: magnetic micro-movement in a bone scaffold. Artif Cells Nanomed Biotechnol. 2018; 46(sup2):636-645. PMID: 30033765.
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    155. Yu X, Xia Y, Zeng L, Zhang X, Chen L, Yan S, Zhang R, Zhao C, Zeng Z, Shu Y, Huang S, Lei J, Yuan C, Zhang L, Feng Y, Liu W, Huang B, Zhang B, Luo W, Wang X, Zhang H, Haydon RC, Luu HH, He TC, Gan H. A blockade of PI3K? signaling effectively mitigates angiotensin II-induced renal injury and fibrosis in a mouse model. Sci Rep. 2018 Jul 20; 8(1):10988. PMID: 30030497; PMCID: PMC6054654.
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    156. Liu M, Gou L, Xia J, Wan Q, Jiang Y, Sun S, Tang M, He T, Zhang Y. LncRNA ITGB2-AS1 Could Promote the Migration and Invasion of Breast Cancer Cells through Up-Regulating ITGB2. Int J Mol Sci. 2018 Jun 25; 19(7). PMID: 29941860; PMCID: PMC6073814.
      Citations: 36     Fields:    Translation:HumansCells
    157. Zhao C, Zeng Z, Qazvini NT, Yu X, Zhang R, Yan S, Shu Y, Zhu Y, Duan C, Bishop E, Lei J, Zhang W, Yang C, Wu K, Wu Y, An L, Huang S, Ji X, Gong C, Yuan C, Zhang L, Liu W, Huang B, Feng Y, Zhang B, Dai Z, Shen Y, Wang X, Luo W, Oliveira L, Athiviraham A, Lee MJ, Wolf JM, Ameer GA, Reid RR, He TC, Huang W. Thermoresponsive Citrate-Based Graphene Oxide Scaffold Enhances Bone Regeneration from BMP9-Stimulated Adipose-Derived Mesenchymal Stem Cells. ACS Biomater Sci Eng. 2018 Aug 13; 4(8):2943-2955. PMID: 30906855; PMCID: PMC6425978.
      Citations: 29     Fields:    
    158. He T, Sun R, Li Y, Katusic ZS. Effects of Brain-Derived Neurotrophic Factor on MicroRNA Expression Profile in Human Endothelial Progenitor Cells. Cell Transplant. 2018 06; 27(6):1005-1009. PMID: 29860902; PMCID: PMC6050915.
      Citations: 7     Fields:    Translation:HumansCells
    159. Yu X, Liu F, Zeng L, He F, Zhang R, Yan S, Zeng Z, Shu Y, Zhao C, Wu X, Lei J, Zhang W, Yang C, Wu K, Wu Y, An L, Huang S, Ji X, Gong C, Yuan C, Zhang L, Feng Y, Huang B, Liu W, Zhang B, Dai Z, Wang X, Liu B, Haydon RC, Luu HH, Gan H, He TC, Chen L. Niclosamide Exhibits Potent Anticancer Activity and Synergizes with Sorafenib in Human Renal Cell Cancer Cells. Cell Physiol Biochem. 2018; 47(3):957-971. PMID: 29843133.
      Citations: 27     Fields:    Translation:Humans
    160. He Y, Fang SY, Bi Y, He TC, Wang Y, Hong SQ. [Twist regulates proliferation, migration and invasion of osteosarcoma cells in vitro]. Nan Fang Yi Ke Da Xue Xue Bao. 2018 May 20; 38(5):554-560. PMID: 29891451; PMCID: PMC6743895.
      Citations: 1     Fields:    Translation:AnimalsCells
    161. Feng Y, Spezia M, Huang S, Yuan C, Zeng Z, Zhang L, Ji X, Liu W, Huang B, Luo W, Liu B, Lei Y, Du S, Vuppalapati A, Luu HH, Haydon RC, He TC, Ren G. Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis. Genes Dis. 2018 Jun; 5(2):77-106. PMID: 30258937; PMCID: PMC6147049.
      Citations: 409     
    162. Yan S, Zhang R, Wu K, Cui J, Huang S, Ji X, An L, Yuan C, Gong C, Zhang L, Liu W, Feng Y, Zhang B, Dai Z, Shen Y, Wang X, Luo W, Liu B, Haydon RC, Lee MJ, Reid RR, Wolf JM, Shi Q, Luu HH, He TC, Weng Y. Characterization of the essential role of bone morphogenetic protein 9 (BMP9) in osteogenic differentiation of mesenchymal stem cells (MSCs) through RNA interference. Genes Dis. 2018 Jun; 5(2):172-184. PMID: 30258947; PMCID: PMC6149187.
      Citations: 25     
    163. Yu X, Chen L, Wu K, Yan S, Zhang R, Zhao C, Zeng Z, Shu Y, Huang S, Lei J, Ji X, Yuan C, Zhang L, Feng Y, Liu W, Huang B, Zhang B, Luo W, Wang X, Liu B, Haydon RC, Luu HH, He TC, Gan H. Establishment and functional characterization of the reversibly immortalized mouse glomerular podocytes (imPODs). Genes Dis. 2018 Jun; 5(2):137-149. PMID: 30258943; PMCID: PMC6147083.
      Citations: 25     
    164. Gou L, Liu M, Xia J, Wan Q, Jiang Y, Sun S, Tang M, Zhou L, He T, Zhang Y. BMP9 Promotes the Proliferation and Migration of Bladder Cancer Cells through Up-Regulating lncRNA UCA1. Int J Mol Sci. 2018 Apr 08; 19(4). PMID: 29642505; PMCID: PMC5979556.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    165. Wang CZ, Huang WH, Zhang CF, Wan JY, Wang Y, Yu C, Williams S, He TC, Du W, Musch MW, Chang EB, Yuan CS. Correction to: Role of intestinal microbiome in American ginseng-mediated colon cancer prevention in high fat diet-fed AOM/DSS mice. Clin Transl Oncol. 2018 03; 20(3):425. PMID: 29027650.
      Citations: 1     Fields:    
    166. Li Y, Liu M, Cui J, Yang K, Zhao L, Gong M, Wang Y, He Y, He T, Bi Y. Hepa1-6-FLuc cell line with the stable expression of firefly luciferase retains its primary properties with promising bioluminescence imaging ability. Oncol Lett. 2018 May; 15(5):6203-6210. PMID: 29616102; PMCID: PMC5876459.
      Citations: 1     
    167. Zeng Z, Huang B, Huang S, Zhang R, Yan S, Yu X, Shu Y, Zhao C, Lei J, Zhang W, Yang C, Wu K, Wu Y, An L, Ji X, Gong C, Yuan C, Zhang L, Liu W, Feng Y, Zhang B, Dai Z, Shen Y, Wang X, Luo W, Haydon RC, Luu HH, Zhou L, Reid RR, He TC, Wu X. The development of a sensitive fluorescent protein-based transcript reporter for high throughput screening of negative modulators of lncRNAs. Genes Dis. 2018 Mar; 5(1):62-74. PMID: 30159383; PMCID: PMC6110536.
      Citations: 17     
    168. Morochnik S, Zhu Y, Duan C, Cai M, Reid RR, He TC, Koh J, Szleifer I, Ameer GA. A thermoresponsive, citrate-based macromolecule for bone regenerative engineering. J Biomed Mater Res A. 2018 06; 106(6):1743-1752. PMID: 29396921; PMCID: PMC5951299.
      Citations: 9     Fields:    Translation:HumansCells
    169. Lyon SM, Mayampurath A, Song D, Ye J, Januszyk M, Rogers MR, Ralston A, Frim DM, He TC, Reid RR. Whole-Proteome Analysis of Human Craniosynostotic Tissue Suggests a Link between Inflammatory Signaling and Osteoclast Activation in Human Cranial Suture Patency. Plast Reconstr Surg. 2018 02; 141(2):250e-260e. PMID: 29369995; PMCID: PMC11005862.
      Citations: 1     Fields:    Translation:HumansCells
    170. Sun R, He T, Pan Y, Katusic ZS. Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells. Aging (Albany NY). 2018 01 15; 10(1):100-114. PMID: 29348391; PMCID: PMC5811245.
      Citations: 10     Fields:    Translation:HumansCells
    171. Hu X, Li L, Yu X, Zhang R, Yan S, Zeng Z, Shu Y, Zhao C, Wu X, Lei J, Li Y, Zhang W, Yang C, Wu K, Wu Y, An L, Huang S, Ji X, Gong C, Yuan C, Zhang L, Liu W, Huang B, Feng Y, Zhang B, Haydon RC, Luu HH, Reid RR, Lee MJ, Wolf JM, Yu Z, He TC. CRISPR/Cas9-mediated reversibly immortalized mouse bone marrow stromal stem cells (BMSCs) retain multipotent features of mesenchymal stem cells (MSCs). Oncotarget. 2017 Dec 19; 8(67):111847-111865. PMID: 29340096; PMCID: PMC5762364.
      Citations: 41     Fields:    
    172. Bishop ES, Mostafa S, Pakvasa M, Luu HH, Lee MJ, Wolf JM, Ameer GA, He TC, Reid RR. 3-D bioprinting technologies in tissue engineering and regenerative medicine: Current and future trends. Genes Dis. 2017 Dec; 4(4):185-195. PMID: 29911158; PMCID: PMC6003668.
      Citations: 183     
    173. Zhao C, Jiang W, Zhou N, Liao J, Yang M, Hu N, Liang X, Xu W, Chen H, Liu W, Shi LL, Oliveira L, Wolf JM, Ho S, Athiviraham A, Tsai HM, He TC, Huang W. Sox9 augments BMP2-induced chondrogenic differentiation by downregulating Smad7 in mesenchymal stem cells (MSCs). Genes Dis. 2017 Dec; 4(4):229-239. PMID: 29503843; PMCID: PMC5831333.
      Citations: 23     
    174. Hui H, Ma W, Cui J, Gong M, Wang Y, Zhang Y, He T, Bi Y, He Y. Periodic acid-Schiff staining method for function detection of liver cells is affected by 2% horse serum in induction medium. Mol Med Rep. 2017 Dec; 16(6):8062-8068. PMID: 28944920; PMCID: PMC5779889.
      Citations: 17     Fields:    Translation:AnimalsCells
    175. Jiang Y, Ren W, Wang W, Xia J, Gou L, Liu M, Wan Q, Zhou L, Weng Y, He T, Zhang Y. Inhibitor of ß-catenin and TCF (ICAT) promotes cervical cancer growth and metastasis by disrupting E-cadherin/ß-catenin complex. Oncol Rep. 2017 Nov; 38(5):2597-2606. PMID: 29048651; PMCID: PMC5780012.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    176. Wang CZ, Huang WH, Zhang CF, Wan JY, Wang Y, Yu C, Williams S, He TC, Du W, Musch MW, Chang EB, Yuan CS. Role of intestinal microbiome in American ginseng-mediated colon cancer prevention in high fat diet-fed AOM/DSS mice [corrected]. Clin Transl Oncol. 2018 03; 20(3):302-312. PMID: 28808878; PMCID: PMC5812846.
      Citations: 18     Fields:    Translation:Animals
    177. Pakvasa M, Alverdy A, Mostafa S, Wang E, Fu L, Li A, Oliveira L, Athiviraham A, Lee MJ, Wolf JM, He TC, Ameer GA, Reid RR. Neural EGF-like protein 1 (NELL-1): Signaling crosstalk in mesenchymal stem cells and applications in regenerative medicine. Genes Dis. 2017 Sep; 4(3):127-137. PMID: 29276737; PMCID: PMC5737940.
      Citations: 17     
    178. Zhang ZC, Liu JX, Shao ZW, Pu FF, Wang BC, Wu Q, Zhang YK, Zeng XL, Guo XD, Yang SH, He TC. In vitro effect of microRNA-107 targeting Dkk-1 by regulation of Wnt/ß-catenin signaling pathway in osteosarcoma. Medicine (Baltimore). 2017 Jul; 96(27):e7245. PMID: 28682874; PMCID: PMC5502147.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    179. Shui YM, Lv GY, Shan LT, Fan CL, Tian N, Gao JL, Zhang L, He TC. Epimedin C Promotes Vascularization during BMP2-Induced Osteogenesis and Tumor-Associated Angiogenesis. Am J Chin Med. 2017; 45(5):1093-1111. PMID: 28659032.
      Citations: 5     Fields:    Translation:AnimalsCells
    180. Liao J, Yu X, Hu X, Fan J, Wang J, Zhang Z, Zhao C, Zeng Z, Shu Y, Zhang R, Yan S, Li Y, Zhang W, Cui J, Ma C, Li L, Yu Y, Wu T, Wu X, Lei J, Wang J, Yang C, Wu K, Wu Y, Tang J, He BC, Deng ZL, Luu HH, Haydon RC, Reid RR, Lee MJ, Wolf JM, Huang W, He TC. lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling. Oncotarget. 2017 Jun 27. PMID: 28668938.
      Citations:    
    181. Liao J, Yu X, Hu X, Fan J, Wang J, Zhang Z, Zhao C, Zeng Z, Shu Y, Zhang R, Yan S, Li Y, Zhang W, Cui J, Ma C, Li L, Yu Y, Wu T, Wu X, Lei J, Wang J, Yang C, Wu K, Wu Y, Tang J, He BC, Deng ZL, Luu HH, Haydon RC, Reid RR, Lee MJ, Wolf JM, Huang W, He TC. lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling. Oncotarget. 2017 Aug 08; 8(32):53581-53601. PMID: 28881833; PMCID: PMC5581132.
      Citations: 67     Fields:    
    182. Wang T, Zhang Z, Wang K, Wang J, Jiang Y, Xia J, Gou L, Liu M, Zhou L, He T, Zhang Y. Inhibitory effects of BMP9 on breast cancer cells by regulating their interaction with pre-adipocytes/adipocytes. Oncotarget. 2017 May 30; 8(22):35890-35901. PMID: 28415788; PMCID: PMC5482625.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    183. Liao J, Wei Q, Fan J, Zou Y, Song D, Liu J, Liu F, Ma C, Hu X, Li L, Yu Y, Qu X, Chen L, Yu X, Zhang Z, Zhao C, Zeng Z, Zhang R, Yan S, Wu T, Wu X, Shu Y, Lei J, Li Y, Zhang W, Wang J, Reid RR, Lee MJ, Huang W, Wolf JM, He TC, Wang J. Characterization of retroviral infectivity and superinfection resistance during retrovirus-mediated transduction of mammalian cells. Gene Ther. 2017 06; 24(6):333-341. PMID: 28387759; PMCID: PMC5506371.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    184. Zou Y, Qazvini NT, Zane K, Sadati M, Wei Q, Liao J, Fan J, Song D, Liu J, Ma C, Qu X, Chen L, Yu X, Zhang Z, Zhao C, Zeng Z, Zhang R, Yan S, Wu T, Wu X, Shu Y, Li Y, Zhang W, Reid RR, Lee MJ, Wolf JM, Tirrell M, He TC, de Pablo JJ, Deng ZL. Gelatin-Derived Graphene-Silicate Hybrid Materials Are Biocompatible and Synergistically Promote BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells. ACS Appl Mater Interfaces. 2017 May 17; 9(19):15922-15932. PMID: 28406027.
      Citations: 20     Fields:    Translation:AnimalsCells
    185. Song D, Zhang F, Reid RR, Ye J, Wei Q, Liao J, Zou Y, Fan J, Ma C, Hu X, Qu X, Chen L, Li L, Yu Y, Yu X, Zhang Z, Zhao C, Zeng Z, Zhang R, Yan S, Wu T, Wu X, Shu Y, Lei J, Li Y, Zhang W, Wang J, Lee MJ, Wolf JM, Huang D, He TC. BMP9 induces osteogenesis and adipogenesis in the immortalized human cranial suture progenitors from the patent sutures of craniosynostosis patients. J Cell Mol Med. 2017 Nov; 21(11):2782-2795. PMID: 28470873; PMCID: PMC5661262.
      Citations: 34     Fields:    Translation:HumansCells
    186. Wei Q, Fan J, Liao J, Zou Y, Song D, Liu J, Cui J, Liu F, Ma C, Hu X, Li L, Yu Y, Qu X, Chen L, Yu X, Zhang Z, Zhao C, Zeng Z, Zhang R, Yan S, Wu X, Shu Y, Reid RR, Lee MJ, Wolf JM, He TC. Engineering the Rapid Adenovirus Production and Amplification (RAPA) Cell Line to Expedite the Generation of Recombinant Adenoviruses. Cell Physiol Biochem. 2017; 41(6):2383-2398. PMID: 28463838.
      Citations: 41     Fields:    Translation:HumansCells
    187. Lee CS, Bishop ES, Zhang R, Yu X, Farina EM, Yan S, Zhao C, Zheng Z, Shu Y, Wu X, Lei J, Li Y, Zhang W, Yang C, Wu K, Wu Y, Ho S, Athiviraham A, Lee MJ, Wolf JM, Reid RR, He TC. Adenovirus-Mediated Gene Delivery: Potential Applications for Gene and Cell-Based Therapies in the New Era of Personalized Medicine. Genes Dis. 2017 Jun; 4(2):43-63. PMID: 28944281; PMCID: PMC5609467.
      Citations: 290     
    188. Xue Q, Yang JF, Li B, He TC, Zhang BQ. [Regulatory effect of faciogenital dysplasia 6 gene on hepatic stem cell differentiation]. Zhonghua Gan Zang Bing Za Zhi. 2017 Apr 20; 25(4):268-272. PMID: 28494545.
      Citations:    Fields:    Translation:HumansAnimalsCells
    189. Fan J, Wei Q, Liao J, Zou Y, Song D, Xiong D, Ma C, Hu X, Qu X, Chen L, Li L, Yu Y, Yu X, Zhang Z, Zhao C, Zeng Z, Zhang R, Yan S, Wu T, Wu X, Shu Y, Lei J, Li Y, Zhang W, Haydon RC, Luu HH, Huang A, He TC, Tang H. Noncanonical Wnt signaling plays an important role in modulating canonical Wnt-regulated stemness, proliferation and terminal differentiation of hepatic progenitors. Oncotarget. 2017 Apr 18; 8(16):27105-27119. PMID: 28404920; PMCID: PMC5432321.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    190. Liu JX, Zhang ZC, Shao ZW, Pu FF, Wang BC, Zhang YK, Zeng XL, Guo XD, Yang SH, He TC. TRAIL-R1 as a novel surface marker for circulating giant cell tumor of bone. Oncotarget. 2017 Aug 01; 8(31):50724-50730. PMID: 28881598; PMCID: PMC5584197.
      Citations: 1     Fields:    
    191. Liao J, Wei Q, Zou Y, Fan J, Song D, Cui J, Zhang W, Zhu Y, Ma C, Hu X, Qu X, Chen L, Yu X, Zhang Z, Wang C, Zhao C, Zeng Z, Zhang R, Yan S, Wu T, Wu X, Shu Y, Lei J, Li Y, Luu HH, Lee MJ, Reid RR, Ameer GA, Wolf JM, He TC, Huang W. Notch Signaling Augments BMP9-Induced Bone Formation by Promoting the Osteogenesis-Angiogenesis Coupling Process in Mesenchymal Stem Cells (MSCs). Cell Physiol Biochem. 2017; 41(5):1905-1923. PMID: 28384643.
      Citations: 57     Fields:    Translation:AnimalsCells
    192. Li F, Hu J, He TC. iPSC-based treatment of age-related macular degeneration (AMD): The path to success requires more than blind faith. Genes Dis. 2017 Jun; 4(2):41-42. PMID: 30258908; PMCID: PMC6136587.
      Citations: 4     
    193. Dumanian ZP, Tollemar V, Ye J, Lu M, Zhu Y, Liao J, Ameer GA, He TC, Reid RR. Repair of critical sized cranial defects with BMP9-transduced calvarial cells delivered in a thermoresponsive scaffold. PLoS One. 2017; 12(3):e0172327. PMID: 28249039; PMCID: PMC5332017.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    194. Zhu P, Wu F, Mosenson J, Zhang H, He TC, Wu WS. CRISPR/Cas9-Mediated Genome Editing Corrects Dystrophin Mutation in Skeletal Muscle Stem Cells in a Mouse Model of Muscle Dystrophy. Mol Ther Nucleic Acids. 2017 Jun 16; 7:31-41. PMID: 28624206; PMCID: PMC5363682.
      Citations: 39     
    195. Zhang F, Li Y, Zhang H, Huang E, Gao L, Luo W, Wei Q, Fan J, Song D, Liao J, Zou Y, Liu F, Liu J, Huang J, Guo D, Ma C, Hu X, Li L, Qu X, Chen L, Yu X, Zhang Z, Wu T, Luu HH, Haydon RC, Song J, He TC, Ji P. Anthelmintic mebendazole enhances cisplatin's effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC). Oncotarget. 2017 Feb 21; 8(8):12968-12982. PMID: 28099902; PMCID: PMC5355070.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    196. Wang J, Liao J, Zhang F, Song D, Lu M, Liu J, Wei Q, Tang S, Liu H, Fan J, Zou Y, Guo D, Huang J, Liu F, Ma C, Hu X, Li L, Qu X, Chen L, Weng Y, Lee MJ, He TC, Reid RR, Zhang J. NEL-Like Molecule-1 (Nell1) Is Regulated by Bone Morphogenetic Protein 9 (BMP9) and Potentiates BMP9-Induced Osteogenic Differentiation at the Expense of Adipogenesis in Mesenchymal Stem Cells. Cell Physiol Biochem. 2017; 41(2):484-500. PMID: 28214873.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    197. Lu M, Liao J, Dong J, Wu J, Qiu H, Zhou X, Li J, Jiang D, He TC, Quan Z. An effective treatment of experimental osteomyelitis using the antimicrobial titanium/silver-containing nHP66 (nano-hydroxyapatite/polyamide-66) nanoscaffold biomaterials. Sci Rep. 2016 12 16; 6:39174. PMID: 27982110; PMCID: PMC5159876.
      Citations: 13     Fields:    Translation:AnimalsCells
    198. Gao JL, Shui YM, Jiang W, Huang EY, Shou QY, Ji X, He BC, Lv GY, He TC. Hypoxia pathway and hypoxia-mediated extensive extramedullary hematopoiesis are involved in ursolic acid's anti-metastatic effect in 4T1 tumor bearing mice. Oncotarget. 2016 Nov 01; 7(44):71802-71816. PMID: 27708244; PMCID: PMC5342124.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    199. Zhang F, Song J, Zhang H, Huang E, Song D, Tollemar V, Wang J, Wang J, Mohammed M, Wei Q, Fan J, Liao J, Zou Y, Liu F, Hu X, Qu X, Chen L, Yu X, Luu HH, Lee MJ, He TC, Ji P. Wnt and BMP Signaling Crosstalk in Regulating Dental Stem Cells: Implications in Dental Tissue Engineering. Genes Dis. 2016 Dec; 3(4):263-276. PMID: 28491933; PMCID: PMC5421560.
      Citations: 33     
    200. Lyon SM, Mayampurath A, Rogers MR, Wolfgeher DJ, Fisher SM, Volchenboum SL, He TC, Reid RR. A method for whole protein isolation from human cranial bone. Anal Biochem. 2016 Dec 15; 515:33-39. PMID: 27677936; PMCID: PMC5584578.
      Citations: 7     Fields:    Translation:HumansAnimals
    201. Lu S, Wang J, Ye J, Zou Y, Zhu Y, Wei Q, Wang X, Tang S, Liu H, Fan J, Zhang F, Farina EM, Mohammed MM, Song D, Liao J, Huang J, Guo D, Lu M, Liu F, Liu J, Li L, Ma C, Hu X, Lee MJ, Reid RR, Ameer GA, Zhou D, He T. Bone morphogenetic protein 9 (BMP9) induces effective bone formation from reversibly immortalized multipotent adipose-derived (iMAD) mesenchymal stem cells. Am J Transl Res. 2016; 8(9):3710-3730. PMID: 27725853; PMCID: PMC5040671.
      Citations: 34     
    202. Uchiyama K, Sakiyama T, Hasebe T, Musch MW, Miyoshi H, Nakagawa Y, He TC, Lichtenstein L, Naito Y, Itoh Y, Yoshikawa T, Jabri B, Stappenbeck T, Chang EB. Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development. Sci Rep. 2016 08 26; 6:32094. PMID: 27561676; PMCID: PMC4999796.
      Citations: 17     Fields:    Translation:AnimalsCells
    203. Zhao B, Shah P, Qiang L, He TC, Budanov A, He YY. Distinct Role of Sesn2 in Response to UVB-Induced DNA Damage and UVA-Induced Oxidative Stress in Melanocytes. Photochem Photobiol. 2017 01; 93(1):375-381. PMID: 27463837; PMCID: PMC5272907.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    204. Deng Y, Wang Z, Zhang F, Qiao M, Yan Z, Wei Q, Wang J, Liu H, Fan J, Zou Y, Liao J, Hu X, Chen L, Yu X, Haydon RC, Luu HH, Qi H, He TC, Zhang J. A Blockade of IGF Signaling Sensitizes Human Ovarian Cancer Cells to the Anthelmintic Niclosamide-Induced Anti-Proliferative and Anticancer Activities. Cell Physiol Biochem. 2016; 39(3):871-88. PMID: 27497986.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    205. Li H, Yuan SM, Yang M, Zha H, Li XR, Sun H, Duan L, Gu Y, Li AF, Weng YG, Luo JY, He TC, Wang Y, Li CY, Li FQ, Wang ZB, Zhou L. High intensity focused ultrasound inhibits melanoma cell migration and metastasis through attenuating microRNA-21-mediated PTEN suppression. Oncotarget. 2016 Aug 02; 7(31):50450-50460. PMID: 27391071; PMCID: PMC5226595.
      Citations: 8     Fields:    Translation:AnimalsCells
    206. Wei Q, Liao J, Yu X, Wang EJ, Wang C, Luu HH, Haydon RC, Lee MJ, He TC. An NgAgo tool for genome editing: did CRISPR/Cas9 just find a competitor? Genes Dis. 2016 Sep; 3(3):169-170. PMID: 28066798; PMCID: PMC5215798.
      Citations: 2     
    207. Ren X, Weisgerber DW, Bischoff D, Lewis MS, Reid RR, He TC, Yamaguchi DT, Miller TA, Harley BA, Lee JC. Nanoparticulate Mineralized Collagen Scaffolds and BMP-9 Induce a Long-Term Bone Cartilage Construct in Human Mesenchymal Stem Cells. Adv Healthc Mater. 2016 07; 5(14):1821-30. PMID: 27275929; PMCID: PMC5404742.
      Citations: 26     Fields:    Translation:HumansCells
    208. Xiang LB, Tu YX, He TC, Pei X, Shen XX, Yang WT, Wu XH, Yang HJ. [Clinical observation of partial pancreatectomy as part of primary cytoreductive surgery in advanced epithelial ovarian cancer]. Zhonghua Fu Chan Ke Za Zhi. 2016 May 25; 51(5):361-5. PMID: 27256444.
      Citations:    Fields:    Translation:HumansAnimals
    209. Ye J, Wang J, Zhu Y, Wei Q, Wang X, Yang J, Tang S, Liu H, Fan J, Zhang F, Farina EM, Mohammed MK, Zou Y, Song D, Liao J, Huang J, Guo D, Lu M, Liu F, Liu J, Li L, Ma C, Hu X, Haydon RC, Lee MJ, Reid RR, Ameer GA, Yang L, He TC. A thermoresponsive polydiolcitrate-gelatin scaffold and delivery system mediates effective bone formation from BMP9-transduced mesenchymal stem cells. Biomed Mater. 2016 Apr 21; 11(2):025021. PMID: 27097687.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    210. Lu S, Wu J, Xu S, Fu B, Dong J, Yang Y, Wang G, Xin M, Li Q, He TC, Wang F, Zhou D. Medial approach to treat humeral mid-shaft fractures: a retrospective study. J Orthop Surg Res. 2016 Mar 17; 11:32. PMID: 26988227; PMCID: PMC4797333.
      Citations: 6     Fields:    Translation:Humans
    211. Lu S, Wu J, Fu B, Dong J, Yang Y, Xin M, Wang G, He TC, Zhou D. Transiliac Osteotomy in Surgical Management of Pelvic Post-Traumatic Malunions: A Retrospective Study. Medicine (Baltimore). 2016 Mar; 95(13):e3144. PMID: 27043674; PMCID: PMC4998535.
      Citations: 4     Fields:    Translation:Humans
    212. Denduluri SK, Scott B, Lamplot JD, Yin L, Yan Z, Wang Z, Ye J, Wang J, Wei Q, Mohammed MK, Haydon RC, Kang RW, He TC, Athiviraham A, Ho SH, Shi LL. Immortalized Mouse Achilles Tenocytes Demonstrate Long-Term Proliferative Capacity While Retaining Tenogenic Properties. Tissue Eng Part C Methods. 2016 Mar; 22(3):280-9. PMID: 26959762; PMCID: PMC4782028.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    213. Wang J, Wei Q, Wang X, Tang S, Liu H, Zhang F, Mohammed MK, Huang J, Guo D, Lu M, Liu F, Liu J, Ma C, Hu X, Haydon RC, He TC, Luu HH. Transition to resistance: An unexpected role of the EMT in cancer chemoresistance. Genes Dis. 2016 Mar; 3(1):3-6. PMID: 28491932; PMCID: PMC5421998.
      Citations: 25     
    214. Mohammed MK, Shao C, Wang J, Wei Q, Wang X, Collier Z, Tang S, Liu H, Zhang F, Huang J, Guo D, Lu M, Liu F, Liu J, Ma C, Shi LL, Athiviraham A, He TC, Lee MJ. Wnt/ß-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance. Genes Dis. 2016 Mar; 3(1):11-40. PMID: 27077077; PMCID: PMC4827448.
      Citations: 141     
    215. Li R, Yan Z, Ye J, Huang H, Wang Z, Wei Q, Wang J, Zhao L, Lu S, Wang X, Tang S, Fan J, Zhang F, Zou Y, Song D, Liao J, Lu M, Liu F, Shi LL, Athiviraham A, Lee MJ, He TC, Zhang Z. The Prodomain-Containing BMP9 Produced from a Stable Line Effectively Regulates the Differentiation of Mesenchymal Stem Cells. Int J Med Sci. 2016; 13(1):8-18. PMID: 26816490; PMCID: PMC4716815.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    216. Wang CZ, Anderson S, DU W, He TC, Yuan CS. Red ginseng and cancer treatment. Chin J Nat Med. 2016 Jan; 14(1):7-16. PMID: 26850342.
      Citations: 68     Fields:    Translation:HumansAnimals
    217. Xie Y, Huang S, He T, Su Y. Coffee consumption and risk of gastric cancer: an updated meta-analysis. Asia Pac J Clin Nutr. 2016; 25(3):578-88. PMID: 27440694.
      Citations: 12     Fields:    Translation:Humans
    218. Li Y, Wagner ER, Yan Z, Wang Z, Luther G, Jiang W, Ye J, Wei Q, Wang J, Zhao L, Lu S, Wang X, Mohammed MK, Tang S, Liu H, Fan J, Zhang F, Zou Y, Song D, Liao J, Haydon RC, Luu HH, He TC. The Calcium-Binding Protein S100A6 Accelerates Human Osteosarcoma Growth by Promoting Cell Proliferation and Inhibiting Osteogenic Differentiation. Cell Physiol Biochem. 2015; 37(6):2375-92. PMID: 26646427.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    219. Deng Y, Zhang J, Wang Z, Yan Z, Qiao M, Ye J, Wei Q, Wang J, Wang X, Zhao L, Lu S, Tang S, Mohammed MK, Liu H, Fan J, Zhang F, Zou Y, Liao J, Qi H, Haydon RC, Luu HH, He TC, Tang L. Antibiotic monensin synergizes with EGFR inhibitors and oxaliplatin to suppress the proliferation of human ovarian cancer cells. Sci Rep. 2015 Dec 07; 5:17523. PMID: 26639992; PMCID: PMC4671000.
      Citations: 41     Fields:    Translation:HumansCells
    220. Yang K, Wang X, Zhang H, Wang Z, Nan G, Li Y, Zhang F, Mohammed MK, Haydon RC, Luu HH, Bi Y, He TC. The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies. Lab Invest. 2016 Feb; 96(2):116-36. PMID: 26618721; PMCID: PMC4731283.
      Citations: 121     Fields:    Translation:HumansAnimalsCells
    221. Yuan SM, Li H, Yang M, Zha H, Sun H, Li XR, Li AF, Gu Y, Duan L, Luo JY, Li CY, Wang Y, Wang ZB, He TC, Zhou L. High intensity focused ultrasound enhances anti-tumor immunity by inhibiting the negative regulatory effect of miR-134 on CD86 in a murine melanoma model. Oncotarget. 2015 Nov 10; 6(35):37626-37. PMID: 26485753; PMCID: PMC4741953.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    222. Green JD, Tollemar V, Dougherty M, Yan Z, Yin L, Ye J, Collier Z, Mohammed MK, Haydon RC, Luu HH, Kang R, Lee MJ, Ho SH, He TC, Shi LL, Athiviraham A. Multifaceted signaling regulators of chondrogenesis: Implications in cartilage regeneration and tissue engineering. Genes Dis. 2015 Dec; 2(4):307-327. PMID: 26835506; PMCID: PMC4730920.
      Citations: 51     
    223. Cui J, Gong M, He Y, Li Q, He T, Bi Y. All-trans retinoic acid inhibits proliferation, migration, invasion and induces differentiation of hepa1-6 cells through reversing EMT in vitro. Int J Oncol. 2016 Jan; 48(1):349-57. PMID: 26548461.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    224. Yin L, Wang Z, Ye J, Zhang Z, Li R, Denduluri SK, Wang J, Wei Q, Zhao L, Lu S, Wang X, Tang S, Shi LL, Lee MJ, He TC, Deng ZL, Yan Z. A Novel Organ Culture Model of Mouse Intervertebral Disc Tissues. Cells Tissues Organs. 2016; 201(1):38-50. PMID: 26447649; PMCID: PMC4710565.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    225. Ding X, Li M, Cao Y, Yang Q, He T, Luo C, Li H, Bi Y. [Effects of Plasmid Fibroblast Growth Factor-2 Magnetic Chitosan Gelatin Microspheres on Proliferation and Differentiation of Mesenchymal Stem Cells]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2015 Oct; 32(5):1083-9. PMID: 26964316.
      Citations:    Fields:    Translation:AnimalsCells
    226. Shao C, Shen C, Lu E, Haydon RC, Luu HH, Athiviraham A, He TC, Lee MJ. Damage control: Harnessing prostaglandin E2 as a potential healing factor of tissue injuries. Genes Dis. 2015 Dec; 2(4):295-298. PMID: 26819965; PMCID: PMC4725599.
      Citations: 1     
    227. Wang W, Weng Y, Ren W, Zhang Z, Wang T, Wang J, Jiang Y, Chen Y, Zhou L, He T, Zhang Y. Biological roles of human bone morphogenetic protein 9 in the bone microenvironment of human breast cancer MDA-MB-231 cells. Am J Transl Res. 2015; 7(9):1660-74. PMID: 26550465; PMCID: PMC4626427.
      Citations: 7     
    228. Denduluri SK, Wang Z, Yan Z, Wang J, Wei Q, Mohammed MK, Haydon RC, Luu HH, He TC. Molecular pathogenesis and therapeutic strategies of human osteosarcoma. J Biomed Res. 2015 Aug 30; 30. PMID: 26496981.
      Citations: 28     
    229. Rong S, Zhu H, Liu D, Qian J, Zhou K, Zhu Q, Jiang Y, Yang G, Deng C, Zhang D, Zhou Q, Lei H, He TC, Wang Z, Huang J. Noninvasive renal denervation for resistant hypertension using high-intensity focused ultrasound. Hypertension. 2015 Oct; 66(4):e22-5. PMID: 26238444.
      Citations: 5     Fields:    Translation:Humans
    230. Hu J, He TC, Li F. For your eyes only: Harnessing human embryonic stem cell-derived retinal pigment epithelial cells to improve impaired vision. Genes Dis. 2015 Dec; 2(4):293-294. PMID: 26819964; PMCID: PMC4725060.
      Citations: 1     
    231. Zhang Q, Wang J, Deng F, Yan Z, Xia Y, Wang Z, Ye J, Deng Y, Zhang Z, Qiao M, Li R, Denduluri SK, Wei Q, Zhao L, Lu S, Wang X, Tang S, Liu H, Luu HH, Haydon RC, He TC, Jiang L. TqPCR: A Touchdown qPCR Assay with Significantly Improved Detection Sensitivity and Amplification Efficiency of SYBR Green qPCR. PLoS One. 2015; 10(7):e0132666. PMID: 26172450; PMCID: PMC4501803.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    232. Li F, Hu J, Xie K, He TC. Authentication of experimental materials: A remedy for the reproducibility crisis? Genes Dis. 2015 Dec; 2(4):283. PMID: 26900588; PMCID: PMC4758512.
      Citations: 3     
    233. Zhang Y, Chee A, Shi P, Wang R, Moss I, Chen EY, He TC, An HS. Allogeneic Articular Chondrocyte Transplantation Downregulates Interleukin 8 Gene Expression in the Degenerating Rabbit Intervertebral Disk In Vivo. Am J Phys Med Rehabil. 2015 Jul; 94(7):530-8. PMID: 25133623; PMCID: PMC4329109.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    234. Wang J, Wei Q, Ye J, Denduluri SK, Wang X, Mohammed MK, Luu HH, Haydon RC, He TC. Insider information: Testing cancer drug sensitivity for personalized therapy. Genes Dis. 2015 Sep; 2(3):219-221. PMID: 26491709; PMCID: PMC4610196.
      Citations: 1     
    235. Zhong L, Gou J, Deng N, Shen H, He T, Zhang BQ. Three-dimensional co-culture of hepatic progenitor cells and mesenchymal stem cells in vitro and in vivo. Microsc Res Tech. 2015 Aug; 78(8):688-96. PMID: 26031767.
      Citations: 3     Fields:    Translation:AnimalsCells
    236. Beederman M, Kim SH, Rogers MR, Lyon SM, He TC, Reid RR. Osteoprotegerin deficiency results in disruption of posterofrontal suture closure in mice: implications in nonsyndromic craniosynostosis. Plast Reconstr Surg. 2015 Jun; 135(6):990e-999e. PMID: 26017615; PMCID: PMC4602410.
      Citations: 2     Fields:    Translation:AnimalsCells
    237. Teven CM, Seitz IA, Rastegar F, Greives MR, He TC, Reid RR, Shenaq DS. Characterization of Reversibly Immortalized Calvarial Mesenchymal Progenitor Cells. J Craniofac Surg. 2015 Jun; 26(4):1207-13. PMID: 26080159; PMCID: PMC4470299.
      Citations: 11     Fields:    Translation:AnimalsCells
    238. He Y, Cui J, He T, Bi Y. 5-azacytidine promotes terminal differentiation of hepatic progenitor cells. Mol Med Rep. 2015 Aug; 12(2):2872-8. PMID: 25975647.
      Citations: 6     Fields:    Translation:AnimalsCells
    239. Li L, Dong Q, Wang Y, Feng Q, Zhou P, Ou X, Meng Q, He T, Luo J. Hedgehog signaling is involved in the BMP9-induced osteogenic differentiation of mesenchymal stem cells. Int J Mol Med. 2015 Jun; 35(6):1641-50. PMID: 25872645.
      Citations: 21     Fields:    Translation:AnimalsCells
    240. Chen X, Cui J, Yan Z, Zhang H, Chen X, Wang N, Shah P, Deng F, Zhao C, Geng N, Li M, Denduluri SK, Haydon RC, Luu HH, Reid RR, He TC. Sustained high level transgene expression in mammalian cells mediated by the optimized piggyBac transposon system. Genes Dis. 2015 Mar; 2(1):96-105. PMID: 25815368; PMCID: PMC4372205.
      Citations: 22     
    241. Li H, Yuan S, Yang M, Duan L, Wang H, Zha H, Li X, Sun H, Weng Y, Luo J, He T, Li C, Wang Y, Li F, Wang Z, Zhou L. [High-intensity focused ultrasound inhibits tumor metastasis in a melanoma-bearing mouse model]. Nan Fang Yi Ke Da Xue Xue Bao. 2015 Feb; 35(2):223-8. PMID: 25736117.
      Citations:    Fields:    Translation:Animals
    242. Wang CZ, Zhang Z, Wan JY, Zhang CF, Anderson S, He X, Yu C, He TC, Qi LW, Yuan CS. Protopanaxadiol, an active ginseng metabolite, significantly enhances the effects of fluorouracil on colon cancer. Nutrients. 2015 Jan 23; 7(2):799-814. PMID: 25625815; PMCID: PMC4344561.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    243. Yu C, Wen XD, Zhang Z, Zhang CF, Wu X, He X, Liao Y, Wu N, Wang CZ, Du W, He TC, Yuan CS. American ginseng significantly reduced the progression of high-fat-diet-enhanced colon carcinogenesis in Apc (Min/+) mice. J Ginseng Res. 2015 Jul; 39(3):230-7. PMID: 26199554; PMCID: PMC4506368.
      Citations: 9     
    244. Teven CM, Fisher S, Ameer GA, He TC, Reid RR. Biomimetic approaches to complex craniofacial defects. Ann Maxillofac Surg. 2015 Jan-Jun; 5(1):4-13. PMID: 26389027; PMCID: PMC4555947.
      Citations: 15     
    245. Liao Z, Nan G, Yan Z, Zeng L, Deng Y, Ye J, Zhang Z, Qiao M, Li R, Denduluri S, Wang J, Wei Q, Geng N, Zhao L, Lu S, Wang X, Zhou G, Luu HH, Haydon RC, He TC, Wang Z. The Anthelmintic Drug Niclosamide Inhibits the Proliferative Activity of Human Osteosarcoma Cells by Targeting Multiple Signal Pathways. Curr Cancer Drug Targets. 2015; 15(8):726-38. PMID: 26118906.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    246. Zhang H, Li L, Dong Q, Wang Y, Feng Q, Ou X, Zhou P, He T, Luo J. Activation of PKA/CREB Signaling is Involved in BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells. Cell Physiol Biochem. 2015; 37(2):548-62. PMID: 26328889.
      Citations: 18     Fields:    Translation:AnimalsCells
    247. Wang Z, Ye J, Deng Y, Yan Z, Denduluri S, He TC. Wnt versus Hippo: A balanced act or dynamic duo? Genes Dis. 2014 Dec 01; 1(2):127-128. PMID: 25679015; PMCID: PMC4323082.
      Citations: 4     
    248. Zhang H, Wang J, Deng F, Huang E, Yan Z, Wang Z, Deng Y, Zhang Q, Zhang Z, Ye J, Qiao M, Li R, Wang J, Wei Q, Zhou G, Luu HH, Haydon RC, He TC, Deng F. Canonical Wnt signaling acts synergistically on BMP9-induced osteo/odontoblastic differentiation of stem cells of dental apical papilla (SCAPs). Biomaterials. 2015 Jan; 39:145-54. PMID: 25468367; PMCID: PMC4258144.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    249. Zhang Z, Li Z, Wu X, Zhang CF, Calway T, He TC, Du W, Chen J, Wang CZ, Yuan CS. TRAIL pathway is associated with inhibition of colon cancer by protopanaxadiol. J Pharmacol Sci. 2015 Jan; 127(1):83-91. PMID: 25704023; PMCID: PMC5053100.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    250. Deng F, Chen X, Liao Z, Yan Z, Wang Z, Deng Y, Zhang Q, Zhang Z, Ye J, Qiao M, Li R, Denduluri S, Wang J, Wei Q, Li M, Geng N, Zhao L, Zhou G, Zhang P, Luu HH, Haydon RC, Reid RR, Yang T, He TC. A simplified and versatile system for the simultaneous expression of multiple siRNAs in mammalian cells using Gibson DNA Assembly. PLoS One. 2014; 9(11):e113064. PMID: 25398142; PMCID: PMC4232585.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    251. Bi Y, He Y, Huang J, Su Y, Zhu GH, Wang Y, Qiao M, Zhang BQ, Zhang H, Wang Z, Liu W, Cui J, Kang Q, Zhang Z, Deng Y, Li R, Zhang Q, Yang K, Luu HH, Haydon RC, He TC, Tang N. Functional characteristics of reversibly immortalized hepatic progenitor cells derived from mouse embryonic liver. Cell Physiol Biochem. 2014; 34(4):1318-38. PMID: 25301359.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    252. Wan S, Liu Y, Weng Y, Wang W, Ren W, Fei C, Chen Y, Zhang Z, Wang T, Wang J, Jiang Y, Zhou L, He T, Zhang Y. BMP9 regulates cross-talk between breast cancer cells and bone marrow-derived mesenchymal stem cells. Cell Oncol (Dordr). 2014 Oct; 37(5):363-75. PMID: 25209393.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    253. Zhang H, Yan Z, Li M, Peabody M, He TC. CRISPR clear? Dimeric Cas9-Fok1 nucleases improve genome-editing specificity. Genes Dis. 2014 Sep; 1(1):6-7. PMID: 25374931; PMCID: PMC4217641.
      Citations: 4     
    254. Huang A, He TC. Genes & Diseases: Moving molecular and translational medicine forward. Genes Dis. 2014 Sep; 1(1):1-3. PMID: 25374930; PMCID: PMC4217640.
      Citations:    
    255. Yu C, Wen XD, Zhang Z, Zhang CF, Wu XH, Martin A, Du W, He TC, Wang CZ, Yuan CS. American ginseng attenuates azoxymethane/dextran sodium sulfate-induced colon carcinogenesis in mice. J Ginseng Res. 2015 Jan; 39(1):14-21. PMID: 25535472; PMCID: PMC4268560.
      Citations: 20     
    256. Zhang Y, Chen X, Qiao M, Zhang BQ, Wang N, Zhang Z, Liao Z, Zeng L, Deng Y, Deng F, Zhang J, Yin L, Liu W, Zhang Q, Ya Z, Ye J, Wang Z, Zhou L, Luu HH, Haydon RC, He TC, Zhang H. Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells. Oncol Rep. 2014 Sep; 32(3):1013-20. PMID: 24993644; PMCID: PMC4121423.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    257. Qiang L, Zhao B, Ming M, Wang N, He TC, Hwang S, Thorburn A, He YY. Regulation of cell proliferation and migration by p62 through stabilization of Twist1. Proc Natl Acad Sci U S A. 2014 Jun 24; 111(25):9241-6. PMID: 24927592; PMCID: PMC4078859.
      Citations: 134     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    258. Wang N, Zhang W, Cui J, Zhang H, Chen X, Li R, Wu N, Chen X, Wen S, Zhang J, Yin L, Deng F, Liao Z, Zhang Z, Zhang Q, Yan Z, Liu W, Ye J, Deng Y, Wang Z, Qiao M, Luu HH, Haydon RC, Shi LL, Liang H, He TC. The piggyBac transposon-mediated expression of SV40 T antigen efficiently immortalizes mouse embryonic fibroblasts (MEFs). PLoS One. 2014; 9(5):e97316. PMID: 24845466; PMCID: PMC4028212.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    259. Ren W, Liu Y, Wan S, Fei C, Wang W, Chen Y, Zhang Z, Wang T, Wang J, Zhou L, Weng Y, He T, Zhang Y. BMP9 inhibits proliferation and metastasis of HER2-positive SK-BR-3 breast cancer cells through ERK1/2 and PI3K/AKT pathways. PLoS One. 2014; 9(5):e96816. PMID: 24805814; PMCID: PMC4013047.
      Citations: 36     Fields:    Translation:HumansCells
    260. Lamplot JD, Liu B, Yin L, Zhang W, Wang Z, Luther G, Wagner E, Li R, Nan G, Shui W, Yan Z, Rames R, Deng F, Zhang H, Liao Z, Liu W, Zhang J, Zhang Z, Zhang Q, Ye J, Deng Y, Qiao M, Haydon RC, Luu HH, Angeles J, Shi LL, He TC, Ho SH. Reversibly Immortalized Mouse Articular Chondrocytes Acquire Long-Term Proliferative Capability While Retaining Chondrogenic Phenotype. Cell Transplant. 2015; 24(6):1053-66. PMID: 24800751.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    261. Wu N, Zhang H, Deng F, Li R, Zhang W, Chen X, Wen S, Wang N, Zhang J, Yin L, Liao Z, Zhang Z, Zhang Q, Yan Z, Liu W, Wu D, Ye J, Deng Y, Yang K, Luu HH, Haydon RC, He TC. Overexpression of Ad5 precursor terminal protein accelerates recombinant adenovirus packaging and amplification in HEK-293 packaging cells. Gene Ther. 2014 Jul; 21(7):629-37. PMID: 24784448.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    262. Wen S, Zhang H, Li Y, Wang N, Zhang W, Yang K, Wu N, Chen X, Deng F, Liao Z, Zhang J, Zhang Q, Yan Z, Liu W, Zhang Z, Ye J, Deng Y, Zhou G, Luu HH, Haydon RC, Shi LL, He TC, Wei G. Characterization of constitutive promoters for piggyBac transposon-mediated stable transgene expression in mesenchymal stem cells (MSCs). PLoS One. 2014; 9(4):e94397. PMID: 24714676; PMCID: PMC3979777.
      Citations: 29     Fields:    Translation:HumansCells
    263. Wang N, Zhang H, Zhang BQ, Liu W, Zhang Z, Qiao M, Zhang H, Deng F, Wu N, Chen X, Wen S, Zhang J, Liao Z, Zhang Q, Yan Z, Yin L, Ye J, Deng Y, Luu HH, Haydon RC, Liang H, He TC. Adenovirus-mediated efficient gene transfer into cultured three-dimensional organoids. PLoS One. 2014; 9(4):e93608. PMID: 24695466; PMCID: PMC3973564.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    264. Wang J, Shi Q, Yuan TX, Song QL, Zhang Y, Wei Q, Zhou L, Luo J, Zuo G, Tang M, He TC, Weng Y. Matrix metalloproteinase 9 (MMP-9) in osteosarcoma: review and meta-analysis. Clin Chim Acta. 2014 Jun 10; 433:225-31. PMID: 24704305.
      Citations: 34     Fields:    Translation:HumansAnimals
    265. Zhao C, Wu N, Deng F, Zhang H, Wang N, Zhang W, Chen X, Wen S, Zhang J, Yin L, Liao Z, Zhang Z, Zhang Q, Yan Z, Liu W, Wu D, Ye J, Deng Y, Zhou G, Luu HH, Haydon RC, Si W, He TC. Adenovirus-mediated gene transfer in mesenchymal stem cells can be significantly enhanced by the cationic polymer polybrene. PLoS One. 2014; 9(3):e92908. PMID: 24658746; PMCID: PMC3962475.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    266. Wang J, Zhang H, Zhang W, Huang E, Wang N, Wu N, Wen S, Chen X, Liao Z, Deng F, Yin L, Zhang J, Zhang Q, Yan Z, Liu W, Zhang Z, Ye J, Deng Y, Luu HH, Haydon RC, He TC, Deng F. Bone morphogenetic protein-9 effectively induces osteo/odontoblastic differentiation of the reversibly immortalized stem cells of dental apical papilla. Stem Cells Dev. 2014 Jun 15; 23(12):1405-16. PMID: 24517722; PMCID: PMC4046201.
      Citations: 64     Fields:    Translation:AnimalsCells
    267. Wang Y, Ta VD, Gao Y, He TC, Chen R, Mutlugun E, Demir HV, Sun HD. Stimulated emission and lasing from CdSe/CdS/ZnS core-multi-shell quantum dots by simultaneous three-photon absorption. Adv Mater. 2014 May; 26(18):2954-61. PMID: 24504537.
      Citations: 12     Fields:    Translation:Cells
    268. Ren W, Sun X, Wang K, Feng H, Liu Y, Fei C, Wan S, Wang W, Luo J, Shi Q, Tang M, Zuo G, Weng Y, He T, Zhang Y. BMP9 inhibits the bone metastasis of breast cancer cells by downregulating CCN2 (connective tissue growth factor, CTGF) expression. Mol Biol Rep. 2014 Mar; 41(3):1373-83. PMID: 24413988.
      Citations: 27     Fields:    Translation:HumansCells
    269. Li R, Zhang W, Cui J, Shui W, Yin L, Wang Y, Zhang H, Wang N, Wu N, Nan G, Chen X, Wen S, Deng F, Zhang H, Zhou G, Liao Z, Zhang J, Zhang Q, Yan Z, Liu W, Zhang Z, Ye J, Deng Y, Luu HH, Haydon RC, He TC, Deng ZL. Targeting BMP9-promoted human osteosarcoma growth by inactivation of notch signaling. Curr Cancer Drug Targets. 2014; 14(3):274-85. PMID: 24605944.
      Citations: 52     Fields:    Translation:HumansCells
    270. Gao Y, Huang E, Zhang H, Wang J, Wu N, Chen X, Wang N, Wen S, Nan G, Deng F, Liao Z, Wu D, Zhang B, Zhang J, Haydon RC, Luu HH, Shi LL, He TC. Crosstalk between Wnt/ß-catenin and estrogen receptor signaling synergistically promotes osteogenic differentiation of mesenchymal progenitor cells. PLoS One. 2013; 8(12):e82436. PMID: 24340027; PMCID: PMC3855436.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    271. Zhang W, Zhang H, Wang N, Zhao C, Zhang H, Deng F, Wu N, He Y, Chen X, Zhang J, Wen S, Liao Z, Zhang Q, Zhang Z, Liu W, Yan Z, Luu HH, Haydon RC, Zhou L, He TC. Modulation of ß-catenin signaling by the inhibitors of MAP kinase, tyrosine kinase, and PI3-kinase pathways. Int J Med Sci. 2013; 10(13):1888-98. PMID: 24324366; PMCID: PMC3856380.
      Citations: 15     Fields:    Translation:HumansCells
    272. Kong Y, Zhang H, Chen X, Zhang W, Zhao C, Wang N, Wu N, He Y, Nan G, Zhang H, Wen S, Deng F, Liao Z, Wu D, Zhang J, Qin X, Haydon RC, Luu HH, He TC, Zhou L. Destabilization of heterologous proteins mediated by the GSK3ß phosphorylation domain of the ß-catenin protein. Cell Physiol Biochem. 2013; 32(5):1187-99. PMID: 24335169; PMCID: PMC4064945.
      Citations: 19     Fields:    Translation:HumansCells
    273. Joseph CG, Hwang H, Jiao Y, Wood LD, Kinde I, Wu J, Mandahl N, Luo J, Hruban RH, Diaz LA, He TC, Vogelstein B, Kinzler KW, Mertens F, Papadopoulos N. Exomic analysis of myxoid liposarcomas, synovial sarcomas, and osteosarcomas. Genes Chromosomes Cancer. 2014 Jan; 53(1):15-24. PMID: 24190505; PMCID: PMC4007004.
      Citations: 54     Fields:    Translation:Humans
    274. Chen X, Luther G, Zhang W, Nan G, Wagner ER, Liao Z, Wu N, Zhang H, Wang N, Wen S, He Y, Deng F, Zhang J, Wu D, Zhang B, Haydon RC, Zhou L, Luu HH, He TC. The E-F hand calcium-binding protein S100A4 regulates the proliferation, survival and differentiation potential of human osteosarcoma cells. Cell Physiol Biochem. 2013; 32(4):1083-96. PMID: 24217649.
      Citations: 28     Fields:    Translation:HumansCells
    275. Shui W, Zhang W, Yin L, Nan G, Liao Z, Zhang H, Wang N, Wu N, Chen X, Wen S, He Y, Deng F, Zhang J, Luu HH, Shi LL, Hu Z, Haydon RC, Mok JM, He TC. Characterization of scaffold carriers for BMP9-transduced osteoblastic progenitor cells in bone regeneration. J Biomed Mater Res A. 2014 Oct; 102(10):3429-38. PMID: 24133046; PMCID: PMC4476251.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    276. Wen XD, Wang CZ, Yu C, Zhao L, Zhang Z, Matin A, Wang Y, Li P, Xiao SY, Du W, He TC, Yuan CS. Panax notoginseng attenuates experimental colitis in the azoxymethane/dextran sulfate sodium mouse model. Phytother Res. 2014 Jun; 28(6):892-8. PMID: 24142591; PMCID: PMC3994185.
      Citations: 16     Fields:    Translation:Animals
    277. Zhang J, Weng Y, Liu X, Wang J, Zhang W, Kim SH, Zhang H, Li R, Kong Y, Chen X, Shui W, Wang N, Zhao C, Wu N, He Y, Nan G, Chen X, Wen S, Zhang H, Deng F, Wan L, Luu HH, Haydon RC, Shi LL, He TC, Shi Q. Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells. PLoS One. 2013; 8(9):e73086. PMID: 24019898; PMCID: PMC3760886.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    278. Bharadwaj S, Liu G, Shi Y, Wu R, Yang B, He T, Fan Y, Lu X, Zhou X, Liu H, Atala A, Rohozinski J, Zhang Y. Multipotential differentiation of human urine-derived stem cells: potential for therapeutic applications in urology. Stem Cells. 2013 Sep; 31(9):1840-56. PMID: 23666768.
      Citations: 168     Fields:    Translation:HumansAnimalsCells
    279. Hu N, Wang C, Liang X, Yin L, Luo X, Liu B, Zhang H, Shui W, Nan G, Wang N, Wu N, Chen X, He Y, Wen S, Deng F, Zhang H, Liao Z, Luu HH, Haydon RC, He TC, Huang W. Inhibition of histone deacetylases potentiates BMP9-induced osteogenic signaling in mouse mesenchymal stem cells. Cell Physiol Biochem. 2013; 32(2):486-98. PMID: 23988723.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    280. Wang W, Xu J, Li L, Dong Q, Shi Q, Zuo G, Zhou L, Weng Y, Tang M, He T, Luo J, Liu Y. Dihydroartemisinin inhibits tumor growth of human osteosarcoma cells by suppressing Wnt/ß-catenin signaling. Oncol Rep. 2013 Oct; 30(4):1723-30. PMID: 23917613.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    281. Beederman M, Lamplot JD, Nan G, Wang J, Liu X, Yin L, Li R, Shui W, Zhang H, Kim SH, Zhang W, Zhang J, Kong Y, Denduluri S, Rogers MR, Pratt A, Haydon RC, Luu HH, Angeles J, Shi LL, He TC. BMP signaling in mesenchymal stem cell differentiation and bone formation. J Biomed Sci Eng. 2013 Aug; 6(8A):32-52. PMID: 26819651; PMCID: PMC4725591.
      Citations: 134     
    282. Bi Y, He Y, Huang JY, Xu L, Tang N, He TC, Feng T. Induced maturation of hepatic progenitor cells in vitro. Braz J Med Biol Res. 2013 Jul; 46(7):559-66. PMID: 23903683; PMCID: PMC3859339.
      Citations: 9     Fields:    Translation:AnimalsCells
    283. Wang Y, Hong S, Li M, Zhang J, Bi Y, He Y, Liu X, Nan G, Su Y, Zhu G, Li R, Zhang W, Wang J, Zhang H, Kong Y, Shui W, Wu N, He Y, Chen X, Luu HH, Haydon RC, Shi LL, He TC, Qin J. Noggin resistance contributes to the potent osteogenic capability of BMP9 in mesenchymal stem cells. J Orthop Res. 2013 Nov; 31(11):1796-803. PMID: 23861103.
      Citations: 60     Fields:    Translation:HumansCells
    284. Liu X, Qin J, Luo Q, Bi Y, Zhu G, Jiang W, Kim SH, Li M, Su Y, Nan G, Cui J, Zhang W, Li R, Chen X, Kong Y, Zhang J, Wang J, Rogers MR, Zhang H, Shui W, Zhao C, Wang N, Liang X, Wu N, He Y, Luu HH, Haydon RC, Shi LL, Li T, He TC, Li M. Cross-talk between EGF and BMP9 signalling pathways regulates the osteogenic differentiation of mesenchymal stem cells. J Cell Mol Med. 2013 Sep; 17(9):1160-72. PMID: 23844832; PMCID: PMC4118175.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    285. Zhou J, He T, Bi Y, Liu C, Su YX. [Effect of BMP-2 and -3 overexpression on osteogenic and chondrogenic differentiation of prenatal mouse intervertebral disc cells in vitro]. Nan Fang Yi Ke Da Xue Xue Bao. 2013 Jul; 33(7):977-82. PMID: 23895836.
      Citations:    Fields:    Translation:AnimalsCells
    286. Li M, Chen Y, Bi Y, Jiang W, Luo Q, He Y, Su Y, Liu X, Cui J, Zhang W, Li R, Kong Y, Zhang J, Wang J, Zhang H, Shui W, Wu N, Zhu J, Tian J, Yi QJ, Luu HH, Haydon RC, He TC, Zhu GH. Establishment and characterization of the reversibly immortalized mouse fetal heart progenitors. Int J Med Sci. 2013; 10(8):1035-46. PMID: 23801891; PMCID: PMC3691803.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    287. He Y, Zhou JW, Xu L, Gong MJ, He TC, Bi Y. Comparison of proliferation and differentiation potential between mouse primary hepatocytes and embryonic hepatic progenitor cells in vitro. Int J Mol Med. 2013 Aug; 32(2):476-84. PMID: 23756629.
      Citations: 7     Fields:    Translation:AnimalsCells
    288. Wang X, Cui J, Zhang BQ, Zhang H, Bi Y, Kang Q, Wang N, Bie P, Yang Z, Wang H, Liu X, Haydon RC, Luu HH, Tang N, Dong J, He TC. Decellularized liver scaffolds effectively support the proliferation and differentiation of mouse fetal hepatic progenitors. J Biomed Mater Res A. 2014 Apr; 102(4):1017-25. PMID: 23625886; PMCID: PMC4056447.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    289. Gao JL, Ji X, He TC, Zhang Q, He K, Zhao Y, Chen SH, Lv GY. Tetrandrine Suppresses Cancer Angiogenesis and Metastasis in 4T1 Tumor Bearing Mice. Evid Based Complement Alternat Med. 2013; 2013:265061. PMID: 23762115; PMCID: PMC3677646.
      Citations: 21     
    290. Zhang Z, Wang CZ, Du GJ, Qi LW, Calway T, He TC, Du W, Yuan CS. Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells. Int J Oncol. 2013 Jul; 43(1):289-96. PMID: 23686257; PMCID: PMC3742162.
      Citations: 71     Fields:    Translation:HumansAnimalsCells
    291. Luther GA, Lamplot J, Chen X, Rames R, Wagner ER, Liu X, Parekh A, Huang E, Kim SH, Shen J, Haydon RC, He TC, Luu HH. IGFBP5 domains exert distinct inhibitory effects on the tumorigenicity and metastasis of human osteosarcoma. Cancer Lett. 2013 Aug 09; 336(1):222-30. PMID: 23665505; PMCID: PMC3704951.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    292. Gao JL, Lv GY, He BC, Zhang BQ, Zhang H, Wang N, Wang CZ, Du W, Yuan CS, He TC. Ginseng saponin metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting multiple cancer signaling pathways. Oncol Rep. 2013 Jul; 30(1):292-8. PMID: 23633038; PMCID: PMC3729206.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    293. Shui W, Yin L, Luo J, Li R, Zhang W, Zhang J, Huang W, Hu N, Liang X, Deng ZL, Hu Z, Shi LL, Luu HH, Haydon RC, He TC, Ho SH. Characterization of chondrocyte scaffold carriers for cell-based gene therapy in articular cartilage repair. J Biomed Mater Res A. 2013 Dec; 101(12):3542-50. PMID: 23629940; PMCID: PMC4056444.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    294. Duan L, Wu R, Ye L, Wang H, Yang X, Zhang Y, Chen X, Zuo G, Zhang Y, Weng Y, Luo J, Tang M, Shi Q, He T, Zhou L. S100A8 and S100A9 are associated with colorectal carcinoma progression and contribute to colorectal carcinoma cell survival and migration via Wnt/ß-catenin pathway. PLoS One. 2013; 8(4):e62092. PMID: 23637971; PMCID: PMC3637369.
      Citations: 60     Fields:    Translation:HumansCells
    295. Wang Q, Guo R, Rong S, Yang G, Zhu Q, Jiang Y, Deng C, Liu D, Zhou Q, Wu Q, Wang S, Qian J, Wang Q, Lei H, He TC, Wang Z, Huang J. Noninvasive renal sympathetic denervation by extracorporeal high-intensity focused ultrasound in a pre-clinical canine model. J Am Coll Cardiol. 2013 May 28; 61(21):2185-92. PMID: 23541964.
      Citations: 20     Fields:    Translation:Animals
    296. Killela PJ, Reitman ZJ, Jiao Y, Bettegowda C, Agrawal N, Diaz LA, Friedman AH, Friedman H, Gallia GL, Giovanella BC, Grollman AP, He TC, He Y, Hruban RH, Jallo GI, Mandahl N, Meeker AK, Mertens F, Netto GJ, Rasheed BA, Riggins GJ, Rosenquist TA, Schiffman M, Shih IeM, Theodorescu D, Torbenson MS, Velculescu VE, Wang TL, Wentzensen N, Wood LD, Zhang M, McLendon RE, Bigner DD, Kinzler KW, Vogelstein B, Papadopoulos N, Yan H. TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proc Natl Acad Sci U S A. 2013 Apr 09; 110(15):6021-6. PMID: 23530248; PMCID: PMC3625331.
      Citations: 745     Fields:    Translation:HumansCells
    297. Lamplot JD, Qin J, Nan G, Wang J, Liu X, Yin L, Tomal J, Li R, Shui W, Zhang H, Kim SH, Zhang W, Zhang J, Kong Y, Denduluri S, Rogers MR, Pratt A, Haydon RC, Luu HH, Angeles J, Shi LL, He TC. BMP9 signaling in stem cell differentiation and osteogenesis. Am J Stem Cells. 2013; 2(1):1-21. PMID: 23671813; PMCID: PMC3636726.
      Citations: 98     
    298. Wu Q, Zhou Q, Zhu Q, Rong S, Wang Q, Guo R, Deng C, Liu D, Yang G, Jiang Y, Wang Z, Lei H, He TC, Wang Z, Huang J. Noninvasive cardiac arrhythmia therapy using High-Intensity Focused Ultrasound (HIFU) ablation. Int J Cardiol. 2013 Jun 20; 166(2):e28-30. PMID: 23484737.
      Citations: 7     Fields:    Translation:Animals
    299. Kim JH, Liu X, Wang J, Chen X, Zhang H, Kim SH, Cui J, Li R, Zhang W, Kong Y, Zhang J, Shui W, Lamplot J, Rogers MR, Zhao C, Wang N, Rajan P, Tomal J, Statz J, Wu N, Luu HH, Haydon RC, He TC. Wnt signaling in bone formation and its therapeutic potential for bone diseases. Ther Adv Musculoskelet Dis. 2013 Feb; 5(1):13-31. PMID: 23514963; PMCID: PMC3582304.
      Citations: 164     
    300. Lamplot JD, Denduluri S, Qin J, Li R, Liu X, Zhang H, Chen X, Wang N, Pratt A, Shui W, Luo X, Nan G, Deng ZL, Luo J, Haydon RC, He TC, Luu HH. The Current and Future Therapies for Human Osteosarcoma. Curr Cancer Ther Rev. 2013 Feb; 9(1):55-77. PMID: 26834515; PMCID: PMC4730918.
      Citations: 33     
    301. Zhang Z, Du GJ, Wang CZ, Wen XD, Calway T, Li Z, He TC, Du W, Bissonnette M, Musch MW, Chang EB, Yuan CS. Compound K, a Ginsenoside Metabolite, Inhibits Colon Cancer Growth via Multiple Pathways Including p53-p21 Interactions. Int J Mol Sci. 2013 Jan 31; 14(2):2980-95. PMID: 23434653; PMCID: PMC3588026.
      Citations: 38     Fields:    
    302. Wu R, Duan L, Ye L, Wang H, Yang X, Zhang Y, Chen X, Zhang Y, Weng Y, Luo J, Tang M, Shi Q, He T, Zhou L. S100A9 promotes the proliferation and invasion of HepG2 hepatocellular carcinoma cells via the activation of the MAPK signaling pathway. Int J Oncol. 2013 Mar; 42(3):1001-10. PMID: 23354417.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    303. Wang CZ, Li B, Wen XD, Zhang Z, Yu C, Calway TD, He TC, Du W, Yuan CS. Paraptosis and NF-?B activation are associated with protopanaxadiol-induced cancer chemoprevention. BMC Complement Altern Med. 2013 Jan 03; 13:2. PMID: 23281928; PMCID: PMC3575249.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    304. Odessey EA, Waggoner DJ, Shenaq DS, Aradhya S, Mitchell A, Whitcomb E, Warshawsky N, He TC, Reid RR, Greives MR. RUNX2 quadruplication: additional evidence toward a new form of syndromic craniosynostosis. J Craniofac Surg. 2013 Jan; 24(1):126-9. PMID: 23348268.
      Citations: 8     Fields:    Translation:Humans
    305. Hu N, Jiang D, Huang E, Liu X, Li R, Liang X, Kim SH, Chen X, Gao JL, Zhang H, Zhang W, Kong YH, Zhang J, Wang J, Shui W, Luo X, Liu B, Cui J, Rogers MR, Shen J, Zhao C, Wang N, Wu N, Luu HH, Haydon RC, He TC, Huang W. BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells. J Cell Sci. 2013 Jan 15; 126(Pt 2):532-41. PMID: 23203800; PMCID: PMC3613181.
      Citations: 71     Fields:    Translation:HumansAnimalsCells
    306. Chenard KE, Teven CM, He TC, Reid RR. Bone morphogenetic proteins in craniofacial surgery: current techniques, clinical experiences, and the future of personalized stem cell therapy. J Biomed Biotechnol. 2012; 2012:601549. PMID: 23226941; PMCID: PMC3511855.
      Citations: 24     Fields:    Translation:HumansAnimals
    307. Li RD, Deng ZL, Hu N, Liang X, Liu B, Luo J, Chen L, Yin L, Luo X, Shui W, He TC, Huang W. Biphasic effects of TGFß1 on BMP9-induced osteogenic differentiation of mesenchymal stem cells. BMB Rep. 2012 Sep; 45(9):509-14. PMID: 23010171.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    308. Huang E, Zhu G, Jiang W, Yang K, Gao Y, Luo Q, Gao JL, Kim SH, Liu X, Li M, Shi Q, Hu N, Wang L, Liu H, Cui J, Zhang W, Li R, Chen X, Kong YH, Zhang J, Wang J, Shen J, Bi Y, Statz J, He BC, Luo J, Wang H, Xiong F, Luu HH, Haydon RC, Yang L, He TC. Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells. J Bone Miner Res. 2012 Jul; 27(7):1566-75. PMID: 22467218.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    309. Yang K, Chen J, Jiang W, Huang E, Cui J, Kim SH, Hu N, Liu H, Zhang W, Li R, Chen X, Kong Y, Zhang J, Wang J, Wang L, Shen J, Luu HH, Haydon RC, Lian X, Yang T, He TC. Conditional immortalization establishes a repertoire of mouse melanocyte progenitors with distinct melanogenic differentiation potential. J Invest Dermatol. 2012 Oct; 132(10):2479-2483. PMID: 22592154; PMCID: PMC4083699.
      Citations: 29     Fields:    Translation:AnimalsCells
    310. Du GJ, Wang CZ, Qi LW, Zhang ZY, Calway T, He TC, Du W, Yuan CS. The synergistic apoptotic interaction of panaxadiol and epigallocatechin gallate in human colorectal cancer cells. Phytother Res. 2013 Feb; 27(2):272-7. PMID: 22566066; PMCID: PMC3416950.
      Citations: 16     Fields:    Translation:HumansCells
    311. Zou W, Zheng H, He TC, Chang J, Fu YX, Fan W. LIGHT delivery to tumors by mesenchymal stem cells mobilizes an effective antitumor immune response. Cancer Res. 2012 Jun 15; 72(12):2980-9. PMID: 22511579.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    312. Yang QJ, Zhou LY, Mu YQ, Zhou QX, Luo JY, Cheng L, Deng ZL, He TC, Haydon RC, He BC. All-trans retinoic acid inhibits tumor growth of human osteosarcoma by activating Smad signaling-induced osteogenic differentiation. Int J Oncol. 2012 Jul; 41(1):153-60. PMID: 22485251.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    313. Teven CM, Greives M, Natale RB, Su Y, Luo Q, He BC, Shenaq D, He TC, Reid RR. Differentiation of osteoprogenitor cells is induced by high-frequency pulsed electromagnetic fields. J Craniofac Surg. 2012 Mar; 23(2):586-93. PMID: 22446422.
      Citations: 17     Fields:    Translation:AnimalsCells
    314. Huang E, Bi Y, Jiang W, Luo X, Yang K, Gao JL, Gao Y, Luo Q, Shi Q, Kim SH, Liu X, Li M, Hu N, Liu H, Cui J, Zhang W, Li R, Chen X, Shen J, Kong Y, Zhang J, Wang J, Luo J, He BC, Wang H, Reid RR, Luu HH, Haydon RC, Yang L, He TC. Conditionally immortalized mouse embryonic fibroblasts retain proliferative activity without compromising multipotent differentiation potential. PLoS One. 2012; 7(2):e32428. PMID: 22384246; PMCID: PMC3285668.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    315. Du GJ, Wang CZ, Zhang ZY, Wen XD, Somogyi J, Calway T, He TC, Du W, Yuan CS. Caspase-mediated pro-apoptotic interaction of panaxadiol and irinotecan in human colorectal cancer cells. J Pharm Pharmacol. 2012 May; 64(5):727-34. PMID: 22471369; PMCID: PMC3349342.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    316. Townsend KL, Suzuki R, Huang TL, Jing E, Schulz TJ, Lee K, Taniguchi CM, Espinoza DO, McDougall LE, Zhang H, He TC, Kokkotou E, Tseng YH. Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway. FASEB J. 2012 May; 26(5):2187-96. PMID: 22331196; PMCID: PMC3336788.
      Citations: 55     Fields:    Translation:AnimalsCells
    317. He T, Katusic ZS. Brain-derived neurotrophic factor increases expression of MnSOD in human circulating angiogenic cells. Microvasc Res. 2012 May; 83(3):366-71. PMID: 22261313; PMCID: PMC3323708.
      Citations: 12     Fields:    Translation:HumansCells
    318. Liu J, Ding X, Tang J, Cao Y, Hu P, Zhou F, Shan X, Cai X, Chen Q, Ling N, Zhang B, Bi Y, Chen K, Ren H, Huang A, He TC, Tang N. Enhancement of canonical Wnt/ß-catenin signaling activity by HCV core protein promotes cell growth of hepatocellular carcinoma cells. PLoS One. 2011; 6(11):e27496. PMID: 22110662; PMCID: PMC3216985.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    319. Peng C, Lu Z, Xie Z, Cheng Z, Chen Y, Tan M, Luo H, Zhang Y, He W, Yang K, Zwaans BM, Tishkoff D, Ho L, Lombard D, He TC, Dai J, Verdin E, Ye Y, Zhao Y. The first identification of lysine malonylation substrates and its regulatory enzyme. Mol Cell Proteomics. 2011 Dec; 10(12):M111.012658. PMID: 21908771; PMCID: PMC3237090.
      Citations: 351     Fields:    Translation:HumansCells
    320. Wang K, Feng H, Ren W, Sun X, Luo J, Tang M, Zhou L, Weng Y, He TC, Zhang Y. BMP9 inhibits the proliferation and invasiveness of breast cancer cells MDA-MB-231. J Cancer Res Clin Oncol. 2011 Nov; 137(11):1687-96. PMID: 21892652.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    321. Teven CM, Liu X, Hu N, Tang N, Kim SH, Huang E, Yang K, Li M, Gao JL, Liu H, Natale RB, Luther G, Luo Q, Wang L, Rames R, Bi Y, Luo J, Luu HH, Haydon RC, Reid RR, He TC. Epigenetic regulation of mesenchymal stem cells: a focus on osteogenic and adipogenic differentiation. Stem Cells Int. 2011; 2011:201371. PMID: 21772852; PMCID: PMC3137957.
      Citations: 58     
    322. Luther G, Wagner ER, Zhu G, Kang Q, Luo Q, Lamplot J, Bi Y, Luo X, Luo J, Teven C, Shi Q, Kim SH, Gao JL, Huang E, Yang K, Rames R, Liu X, Li M, Hu N, Liu H, Su Y, Chen L, He BC, Zuo GW, Deng ZL, Reid RR, Luu HH, Haydon RC, He TC. BMP-9 induced osteogenic differentiation of mesenchymal stem cells: molecular mechanism and therapeutic potential. Curr Gene Ther. 2011 Jun; 11(3):229-40. PMID: 21453282.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    323. Lee JC, Spiguel L, Shenaq DS, Zhong M, Wietholt C, He TC, Reid RR. Role of RANK-RANKL-OPG axis in cranial suture homeostasis. J Craniofac Surg. 2011 Mar; 22(2):699-705. PMID: 21415639.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    324. Wagner ER, Luther G, Zhu G, Luo Q, Shi Q, Kim SH, Gao JL, Huang E, Gao Y, Yang K, Wang L, Teven C, Luo X, Liu X, Li M, Hu N, Su Y, Bi Y, He BC, Tang N, Luo J, Chen L, Zuo G, Rames R, Haydon RC, Luu HH, He TC. Defective osteogenic differentiation in the development of osteosarcoma. Sarcoma. 2011; 2011:325238. PMID: 21437219; PMCID: PMC3061279.
      Citations: 47     
    325. He Y, Zhang WY, Gong M, Huang JY, Tang N, Feng T, Wei GH, He TC, Bi Y. Low serum concentration facilitates the differentiation of hepatic progenitor cells. Saudi Med J. 2011 Feb; 32(2):128-34. PMID: 21301757.
      Citations: 5     Fields:    Translation:AnimalsCells
    326. Wagner ER, Zhu G, Zhang BQ, Luo Q, Shi Q, Huang E, Gao Y, Gao JL, Kim SH, Rastegar F, Yang K, He BC, Chen L, Zuo GW, Bi Y, Su Y, Luo J, Luo X, Huang J, Deng ZL, Reid RR, Luu HH, Haydon RC, He TC. The therapeutic potential of the Wnt signaling pathway in bone disorders. Curr Mol Pharmacol. 2011 Jan; 4(1):14-25. PMID: 20825362.
      Citations: 35     Fields:    Translation:HumansCells
    327. Li B, Zhao J, Wang CZ, Searle J, He TC, Yuan CS, Du W. Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53. Cancer Lett. 2011 Feb 28; 301(2):185-92. PMID: 21194832; PMCID: PMC3022099.
      Citations: 110     Fields:    Translation:HumansCells
    328. Shenaq DS, Rastegar F, Petkovic D, Zhang BQ, He BC, Chen L, Zuo GW, Luo Q, Shi Q, Wagner ER, Huang E, Gao Y, Gao JL, Kim SH, Yang K, Bi Y, Su Y, Zhu G, Luo J, Luo X, Qin J, Reid RR, Luu HH, Haydon RC, He TC. Mesenchymal Progenitor Cells and Their Orthopedic Applications: Forging a Path towards Clinical Trials. Stem Cells Int. 2010 Dec 16; 2010:519028. PMID: 21234334; PMCID: PMC3017936.
      Citations: 34     
    329. He BC, Gao JL, Luo X, Luo J, Shen J, Wang L, Zhou Q, Wang YT, Luu HH, Haydon RC, Wang CZ, Du W, Yuan CS, He TC, Zhang BQ. Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/ß-catenin signaling. Int J Oncol. 2011 Feb; 38(2):437-45. PMID: 21152855.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    330. Rastegar F, Gao JL, Shenaq D, Luo Q, Shi Q, Kim SH, Jiang W, Wagner ER, Huang E, Gao Y, Shen J, Yang K, He BC, Chen L, Zuo GW, Luo J, Luo X, Bi Y, Liu X, Li M, Hu N, Wang L, Luther G, Luu HH, Haydon RC, He TC. Lysophosphatidic acid acyltransferase ß (LPAATß) promotes the tumor growth of human osteosarcoma. PLoS One. 2010 Dec 01; 5(12):e14182. PMID: 21152068; PMCID: PMC2995727.
      Citations: 26     Fields:    Translation:HumansCells
    331. Chen L, Jiang W, Huang J, He BC, Zuo GW, Zhang W, Luo Q, Shi Q, Zhang BQ, Wagner ER, Luo J, Tang M, Wietholt C, Luo X, Bi Y, Su Y, Liu B, Kim SH, He CJ, Hu Y, Shen J, Rastegar F, Huang E, Gao Y, Gao JL, Zhou JZ, Reid RR, Luu HH, Haydon RC, He TC, Deng ZL. Insulin-like growth factor 2 (IGF-2) potentiates BMP-9-induced osteogenic differentiation and bone formation. J Bone Miner Res. 2010 Nov; 25(11):2447-59. PMID: 20499340; PMCID: PMC3179288.
      Citations: 133     Fields:    Translation:HumansAnimalsCells
    332. He BC, Gao JL, Zhang BQ, Luo Q, Shi Q, Kim SH, Huang E, Gao Y, Yang K, Wagner ER, Wang L, Tang N, Luo J, Liu X, Li M, Bi Y, Shen J, Luther G, Hu N, Zhou Q, Luu HH, Haydon RC, Zhao Y, He TC. Tetrandrine inhibits Wnt/ß-catenin signaling and suppresses tumor growth of human colorectal cancer. Mol Pharmacol. 2011 Feb; 79(2):211-9. PMID: 20978119; PMCID: PMC3033706.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    333. Rastegar F, Shenaq D, Huang J, Zhang W, Zhang BQ, He BC, Chen L, Zuo GW, Luo Q, Shi Q, Wagner ER, Huang E, Gao Y, Gao JL, Kim SH, Zhou JZ, Bi Y, Su Y, Zhu G, Luo J, Luo X, Qin J, Reid RR, Luu HH, Haydon RC, Deng ZL, He TC. Mesenchymal stem cells: Molecular characteristics and clinical applications. World J Stem Cells. 2010 Aug 26; 2(4):67-80. PMID: 21607123; PMCID: PMC3097925.
      Citations: 99     
    334. Zhang W, Deng ZL, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Wagner ER, Rastegar F, Kim SH, Jiang W, Shen J, Huang E, Gao Y, Gao JL, Zhou JZ, Luo J, Huang J, Luo X, Bi Y, Su Y, Yang K, Liu H, Luu HH, Haydon RC, He TC, He BC. Retinoic acids potentiate BMP9-induced osteogenic differentiation of mesenchymal progenitor cells. PLoS One. 2010 Jul 30; 5(7):e11917. PMID: 20689834; PMCID: PMC2912873.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    335. Luo J, Tang M, Huang J, He BC, Gao JL, Chen L, Zuo GW, Zhang W, Luo Q, Shi Q, Zhang BQ, Bi Y, Luo X, Jiang W, Su Y, Shen J, Kim SH, Huang E, Gao Y, Zhou JZ, Yang K, Luu HH, Pan X, Haydon RC, Deng ZL, He TC. TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells. J Biol Chem. 2010 Sep 17; 285(38):29588-98. PMID: 20628059; PMCID: PMC2937990.
      Citations: 96     Fields:    Translation:HumansAnimalsCells
    336. Zuo GW, Kohls CD, He BC, Chen L, Zhang W, Shi Q, Zhang BQ, Kang Q, Luo J, Luo X, Wagner ER, Kim SH, Restegar F, Haydon RC, Deng ZL, Luu HH, He TC, Luo Q. The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis. Histol Histopathol. 2010 06; 25(6):795-806. PMID: 20376786; PMCID: PMC2922104.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    337. Bi Y, Gong M, Zhang X, Zhang X, Jiang W, Zhang Y, Chen J, Liu Y, He TC, Li T. Pre-activation of retinoid signaling facilitates neuronal differentiation of mesenchymal stem cells. Dev Growth Differ. 2010 Jun; 52(5):419-31. PMID: 20507357.
      Citations: 26     Fields:    Translation:AnimalsCells
    338. He BC, Chen L, Zuo GW, Zhang W, Bi Y, Huang J, Wang Y, Jiang W, Luo Q, Shi Q, Zhang BQ, Liu B, Lei X, Luo J, Luo X, Wagner ER, Kim SH, He CJ, Hu Y, Shen J, Zhou Q, Rastegar F, Deng ZL, Luu HH, He TC, Haydon RC. Synergistic antitumor effect of the activated PPARgamma and retinoid receptors on human osteosarcoma. Clin Cancer Res. 2010 Apr 15; 16(8):2235-45. PMID: 20371684.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    339. Wagner ER, He BC, Chen L, Zuo GW, Zhang W, Shi Q, Luo Q, Luo X, Liu B, Luo J, Rastegar F, He CJ, Hu Y, Boody B, Luu HH, He TC, Deng ZL, Haydon RC. Therapeutic Implications of PPARgamma in Human Osteosarcoma. PPAR Res. 2010; 2010:956427. PMID: 20182546; PMCID: PMC2825651.
      Citations: 21     
    340. Han W, Ming M, He TC, He YY. Immunosuppressive cyclosporin A activates AKT in keratinocytes through PTEN suppression: implications in skin carcinogenesis. J Biol Chem. 2010 Apr 09; 285(15):11369-77. PMID: 20154081; PMCID: PMC2857015.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    341. Luther G, Rames R, Wagner ER, Zhu G, Luo Q, Bi Y, Kim SH, Gao JL, Huang E, Yang K, Wang L, Liu X, Li M, Hu N, Su Y, Luo X, Chen L, Luo J, Haydon RC, Luu HH, Zhou L, He TC. Molecular basis of differentiation therapy for soft tissue sarcomas. Trends Cancer Res. 2010; 6:69-90. PMID: 26912947; PMCID: PMC4762605.
      Citations: 3     
    342. Gao JL, He TC, Li YB, Wang YT. A traditional Chinese medicine formulation consisting of Rhizoma Corydalis and Rhizoma Curcumae exerts synergistic anti-tumor activity. Oncol Rep. 2009 Nov; 22(5):1077-83. PMID: 19787224.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    343. Li XL, Wang CZ, Sun S, Mehendale SR, Du W, He TC, Yuan CS. American ginseng berry enhances chemopreventive effect of 5-FU on human colorectal cancer cells. Oncol Rep. 2009 Oct; 22(4):943-52. PMID: 19724877.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    344. Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N. Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov; 29(10):1569-81. PMID: 19737349.
      Citations: 52     Fields:    Translation:AnimalsCells
    345. Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N. Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Sep 01; 108(1):295-303. PMID: 19562671.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    346. Xie JT, Wang CZ, Zhang B, Mehendale SR, Li XL, Sun S, Han AH, Du W, He TC, Yuan CS. In vitro and in vivo anticancer effects of American ginseng berry: exploring representative compounds. Biol Pharm Bull. 2009 Sep; 32(9):1552-8. PMID: 19721231.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    347. Li B, Wang CZ, He TC, Yuan CS, Du W. Antioxidants potentiate American ginseng-induced killing of colorectal cancer cells. Cancer Lett. 2010 Mar 01; 289(1):62-70. PMID: 19716228; PMCID: PMC2824022.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    348. Zhu GH, Huang J, Bi Y, Su Y, Tang Y, He BC, He Y, Luo J, Wang Y, Chen L, Zuo GW, Jiang W, Luo Q, Shen J, Liu B, Zhang WL, Shi Q, Zhang BQ, Kang Q, Zhu J, Tian J, Luu HH, Haydon RC, Chen Y, He TC. Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells. Differentiation. 2009 Nov; 78(4):195-204. PMID: 19560855; PMCID: PMC2829657.
      Citations: 54     Fields:    Translation:AnimalsCells
    349. Zhang Y, Markova D, Im HJ, Hu W, Thonar EJ, He TC, An HS, Phillips FM, Anderson DG. Primary bovine intervertebral disc cells transduced with adenovirus overexpressing 12 BMPs and Sox9 maintain appropriate phenotype. Am J Phys Med Rehabil. 2009 Jun; 88(6):455-63. PMID: 19454853; PMCID: PMC2894691.
      Citations: 5     Fields:    Translation:AnimalsCells
    350. Freeman-Anderson NE, Zheng Y, McCalla-Martin AC, Treanor LM, Zhao YD, Garfin PM, He TC, Mary MN, Thornton JD, Anderson C, Gibbons M, Saab R, Baumer SH, Cunningham JM, Skapek SX. Expression of the Arf tumor suppressor gene is controlled by Tgfbeta2 during development. Development. 2009 Jun; 136(12):2081-9. PMID: 19465598; PMCID: PMC2685726.
      Citations: 24     Fields:    Translation:AnimalsCells
    351. Kang Q, Song WX, Luo Q, Tang N, Luo J, Luo X, Chen J, Bi Y, He BC, Park JK, Jiang W, Tang Y, Huang J, Su Y, Zhu GH, He Y, Yin H, Hu Z, Wang Y, Chen L, Zuo GW, Pan X, Shen J, Vokes T, Reid RR, Haydon RC, Luu HH, He TC. A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells. Stem Cells Dev. 2009 May; 18(4):545-59. PMID: 18616389; PMCID: PMC3132950.
      Citations: 190     Fields:    Translation:HumansAnimalsCells
    352. Su Y, Luo X, He BC, Wang Y, Chen L, Zuo GW, Liu B, Bi Y, Huang J, Zhu GH, He Y, Kang Q, Luo J, Shen J, Chen J, Jin X, Haydon RC, He TC, Luu HH. Establishment and characterization of a new highly metastatic human osteosarcoma cell line. Clin Exp Metastasis. 2009; 26(7):599-610. PMID: 19363654.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    353. Ulasov IV, Tyler MA, Zhu ZB, Han Y, He TC, Lesniak MS. Oncolytic adenoviral vectors which employ the survivin promoter induce glioma oncolysis via a process of beclin-dependent autophagy. Int J Oncol. 2009 Mar; 34(3):729-42. PMID: 19212678; PMCID: PMC2790828.
      Citations: 22     Fields:    Translation:HumansCells
    354. Zhu D, Kang Q, Huang PY, He TC, Xie P. Neurogenesis-related genes expression profiling of mouse fibroblastic stem cells induced by Wnt signaling. Neurol Res. 2009 Mar; 31(2):200-3. PMID: 19298762.
      Citations: 6     Fields:    Translation:AnimalsCells
    355. Wang CZ, Xie JT, Fishbein A, Aung HH, He H, Mehendale SR, He TC, Du W, Yuan CS. Antiproliferative effects of different plant parts of Panax notoginseng on SW480 human colorectal cancer cells. Phytother Res. 2009 Jan; 23(1):6-13. PMID: 19048608; PMCID: PMC2676878.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    356. Sharff KA, Song WX, Luo X, Tang N, Luo J, Chen J, Bi Y, He BC, Huang J, Li X, Jiang W, Zhu GH, Su Y, He Y, Shen J, Wang Y, Chen L, Zuo GW, Liu B, Pan X, Reid RR, Luu HH, Haydon RC, He TC. Hey1 basic helix-loop-helix protein plays an important role in mediating BMP9-induced osteogenic differentiation of mesenchymal progenitor cells. J Biol Chem. 2009 Jan 02; 284(1):649-659. PMID: 18986983; PMCID: PMC2610517.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    357. Tang N, Song WX, Luo J, Luo X, Chen J, Sharff KA, Bi Y, He BC, Huang JY, Zhu GH, Su YX, Jiang W, Tang M, He Y, Wang Y, Chen L, Zuo GW, Shen J, Pan X, Reid RR, Luu HH, Haydon RC, He TC. BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signalling. J Cell Mol Med. 2009 Aug; 13(8B):2448-2464. PMID: 19175684; PMCID: PMC4940786.
      Citations: 132     Fields:    Translation:HumansAnimalsCells
    358. Luo X, Chen J, Song WX, Tang N, Luo J, Deng ZL, Sharff KA, He G, Bi Y, He BC, Bennett E, Huang J, Kang Q, Jiang W, Su Y, Zhu GH, Yin H, He Y, Wang Y, Souris JS, Chen L, Zuo GW, Montag AG, Reid RR, Haydon RC, Luu HH, He TC. Osteogenic BMPs promote tumor growth of human osteosarcomas that harbor differentiation defects. Lab Invest. 2008 Dec; 88(12):1264-77. PMID: 18838962; PMCID: PMC9901484.
      Citations: 104     Fields:    Translation:HumansAnimalsCells
    359. Wang CZ, Aung HH, Zhang B, Sun S, Li XL, He H, Xie JT, He TC, Du W, Yuan CS. Chemopreventive effects of heat-processed Panax quinquefolius root on human breast cancer cells. Anticancer Res. 2008 Sep-Oct; 28(5A):2545-51. PMID: 19035277; PMCID: PMC2676904.
      Citations: 38     Fields:    Translation:HumansAnimals
    360. Luo X, Sharff KA, Chen J, He TC, Luu HH. S100A6 expression and function in human osteosarcoma. Clin Orthop Relat Res. 2008 Sep; 466(9):2060-70. PMID: 18612712; PMCID: PMC2493010.
      Citations: 23     Fields:    Translation:HumansCells
    361. Tang N, Song WX, Luo J, Haydon RC, He TC. Osteosarcoma development and stem cell differentiation. Clin Orthop Relat Res. 2008 Sep; 466(9):2114-30. PMID: 18563507; PMCID: PMC2492997.
      Citations: 179     Fields:    Translation:HumansCells
    362. Luo X, Wang CZ, Chen J, Song WX, Luo J, Tang N, He BC, Kang Q, Wang Y, Du W, He TC, Yuan CS. Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells. Int J Oncol. 2008 May; 32(5):975-83. PMID: 18425323; PMCID: PMC2677725.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    363. Zhang Y, Phillips FM, Thonar EJ, Oegema T, An HS, Roman-Blas JA, He TC, Anderson DG. Cell therapy using articular chondrocytes overexpressing BMP-7 or BMP-10 in a rabbit disc organ culture model. Spine (Phila Pa 1976). 2008 Apr 15; 33(8):831-8. PMID: 18404100.
      Citations: 13     Fields:    Translation:AnimalsCells
    364. Deng ZL, Sharff KA, Tang N, Song WX, Luo J, Luo X, Chen J, Bennett E, Reid R, Manning D, Xue A, Montag AG, Luu HH, Haydon RC, He TC. Regulation of osteogenic differentiation during skeletal development. Front Biosci. 2008 Jan 01; 13:2001-21. PMID: 17981687.
      Citations: 160     Fields:    Translation:HumansAnimalsCells
    365. Cho S, Bian J, Pelizzari CA, Chen CT, He TC, Pan X. Region-of-interest image reconstruction in circular cone-beam microCT. Med Phys. 2007 Dec; 34(12):4923-33. PMID: 18196817.
      Citations: 13     Fields:    Translation:HumansAnimals
    366. Wang CZ, Xie JT, Zhang B, Ni M, Fishbein A, Aung HH, Mehendale SR, Du W, He TC, Yuan CS. Chemopreventive effects of Panax notoginseng and its major constituents on SW480 human colorectal cancer cells. Int J Oncol. 2007 Nov; 31(5):1149-56. PMID: 17912442; PMCID: PMC2676859.
      Citations: 29     Fields:    Translation:HumansCells
    367. Zhang Y, Anderson DG, Phillips FM, Thonar EJ, He TC, Pietryla D, An HS. Comparative effects of bone morphogenetic proteins and Sox9 overexpression on matrix accumulation by bovine anulus fibrosus cells: implications for anular repair. Spine (Phila Pa 1976). 2007 Nov 01; 32(23):2515-20. PMID: 17978648.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    368. Li TJ, Song JN, Kang K, Tong SS, Hu ZL, He TC, Zhang BQ, Zhang CQ. RNA interference-mediated gene silencing of vascular endothelial growth factor in colon cancer cells. World J Gastroenterol. 2007 Oct 28; 13(40):5312-6. PMID: 17879399; PMCID: PMC4171319.
      Citations: 2     Fields:    Translation:HumansCells
    369. Bolt P, Clerk AN, Luu HH, Kang Q, Kummer JL, Deng ZL, Olson K, Primus F, Montag AG, He TC, Haydon RC, Toolan BC. BMP-14 gene therapy increases tendon tensile strength in a rat model of Achilles tendon injury. J Bone Joint Surg Am. 2007 Jun; 89(6):1315-20. PMID: 17545436.
      Citations: 49     Fields:    Translation:AnimalsCells
    370. Wang CZ, Aung HH, Ni M, Wu JA, Tong R, Wicks S, He TC, Yuan CS. Red American ginseng: ginsenoside constituents and antiproliferative activities of heat-processed Panax quinquefolius roots. Planta Med. 2007 Jun; 73(7):669-74. PMID: 17538869; PMCID: PMC2657361.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    371. Luu HH, Song WX, Luo X, Manning D, Luo J, Deng ZL, Sharff KA, Montag AG, Haydon RC, He TC. Distinct roles of bone morphogenetic proteins in osteogenic differentiation of mesenchymal stem cells. J Orthop Res. 2007 May; 25(5):665-77. PMID: 17290432.
      Citations: 241     Fields:    Translation:HumansAnimalsCells
    372. Luo Q, Kang Q, Song WX, Luu HH, Luo X, An N, Luo J, Deng ZL, Jiang W, Yin H, Chen J, Sharff KA, Tang N, Bennett E, Haydon RC, He TC. Selection and validation of optimal siRNA target sites for RNAi-mediated gene silencing. Gene. 2007 Jun 15; 395(1-2):160-9. PMID: 17449199.
      Citations: 36     Fields:    Translation:HumansCells
    373. Luo J, Chen J, Deng ZL, Luo X, Song WX, Sharff KA, Tang N, Haydon RC, Luu HH, He TC. Wnt signaling and human diseases: what are the therapeutic implications? Lab Invest. 2007 Feb; 87(2):97-103. PMID: 17211410.
      Citations: 79     Fields:    Translation:HumansCells
    374. Haydon RC, Luu HH, He TC. Osteosarcoma and osteoblastic differentiation: a new perspective on oncogenesis. Clin Orthop Relat Res. 2007 Jan; 454:237-46. PMID: 17075380.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    375. Luo J, Deng ZL, Luo X, Tang N, Song WX, Chen J, Sharff KA, Luu HH, Haydon RC, Kinzler KW, Vogelstein B, He TC. A protocol for rapid generation of recombinant adenoviruses using the AdEasy system. Nat Protoc. 2007; 2(5):1236-47. PMID: 17546019.
      Citations: 445     Fields:    Translation:HumansCells
    376. Wang CZ, Zhang B, Song WX, Wang A, Ni M, Luo X, Aung HH, Xie JT, Tong R, He TC, Yuan CS. Steamed American ginseng berry: ginsenoside analyses and anticancer activities. J Agric Food Chem. 2006 Dec 27; 54(26):9936-42. PMID: 17177524.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    377. Wang CZ, Luo X, Zhang B, Song WX, Ni M, Mehendale S, Xie JT, Aung HH, He TC, Yuan CS. Notoginseng enhances anti-cancer effect of 5-fluorouracil on human colorectal cancer cells. Cancer Chemother Pharmacol. 2007 Jun; 60(1):69-79. PMID: 17009031; PMCID: PMC2657471.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    378. Zhang BQ, Huang Y, Tang N, Wu Y, Zhang J, Chen WX, He TC, Huang AL. [Inhibition of HBV replication and antigen expression by RNA interference against different targets]. Zhonghua Gan Zang Bing Za Zhi. 2006 Sep; 14(9):662-5. PMID: 16995979.
      Citations:    Fields:    Translation:HumansCells
    379. Zhang Y, An HS, Thonar EJ, Chubinskaya S, He TC, Phillips FM. Comparative effects of bone morphogenetic proteins and sox9 overexpression on extracellular matrix metabolism of bovine nucleus pulposus cells. Spine (Phila Pa 1976). 2006 Sep 01; 31(19):2173-9. PMID: 16946650.
      Citations: 14     Fields:    Translation:AnimalsCells
    380. Si W, Kang Q, Luu HH, Park JK, Luo Q, Song WX, Jiang W, Luo X, Li X, Yin H, Montag AG, Haydon RC, He TC. CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells. Mol Cell Biol. 2006 Apr; 26(8):2955-64. PMID: 16581771; PMCID: PMC1446962.
      Citations: 142     Fields:    Translation:HumansCells
    381. Zhang Y, Li Z, Thonar EJ, An HS, He TC, Pietryla D, Phillips FM. Transduced bovine articular chondrocytes affect the metabolism of cocultured nucleus pulposus cells in vitro: implications for chondrocyte transplantation into the intervertebral disc. Spine (Phila Pa 1976). 2005 Dec 01; 30(23):2601-7. PMID: 16319745.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    382. Luu HH, Zhou L, Haydon RC, Deyrup AT, Montag AG, Huo D, Heck R, Heizmann CW, Peabody TD, Simon MA, He TC. Increased expression of S100A6 is associated with decreased metastasis and inhibition of cell migration and anchorage independent growth in human osteosarcoma. Cancer Lett. 2005 Nov 08; 229(1):135-48. PMID: 16157226.
      Citations: 43     Fields:    Translation:HumansCells
    383. Phillips FM, Bolt PM, He TC, Haydon RC. Gene therapy for spinal fusion. Spine J. 2005 Nov-Dec; 5(6 Suppl):250S-258S. PMID: 16291120.
      Citations: 3     Fields:    Translation:HumansAnimals
    384. He TC. Distinct osteogenic activity of BMPs and their orthopaedic applications. J Musculoskelet Neuronal Interact. 2005 Oct-Dec; 5(4):363-6. PMID: 16340140.
      Citations: 15     Fields:    Translation:AnimalsCells
    385. Tao P, Zhang J, Tang N, Zhang BQ, He TC, Huang AL. Potent and specific inhibition of SARS-CoV antigen expression by RNA interference. Chin Med J (Engl). 2005 May 05; 118(9):714-9. PMID: 15899131.
      Citations: 6     Fields:    Translation:HumansCells
    386. Luo J, Sun MH, Kang Q, Peng Y, Jiang W, Luu HH, Luo Q, Park JY, Li Y, Haydon RC, He TC. Gene therapy for bone regeneration. Curr Gene Ther. 2005 Apr; 5(2):167-79. PMID: 15853725.
      Citations: 49     Fields:    Translation:HumansAnimals
    387. Sun J, Hobert ME, Duan Y, Rao AS, He TC, Chang EB, Madara JL. Crosstalk between NF-kappaB and beta-catenin pathways in bacterial-colonized intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2005 Jul; 289(1):G129-37. PMID: 15790758.
      Citations: 71     Fields:    Translation:HumansCells
    388. Akintola-Ogunremi O, Luo Q, He TC, Wang HL. Is cytomegalovirus associated with human colorectal tumorigenesis? Am J Clin Pathol. 2005 Feb; 123(2):244-9. PMID: 15842049.
      Citations: 17     Fields:    Translation:HumansCells
    389. Luu HH, Kang Q, Park JK, Si W, Luo Q, Jiang W, Yin H, Montag AG, Simon MA, Peabody TD, Haydon RC, Rinker-Schaeffer CW, He TC. An orthotopic model of human osteosarcoma growth and spontaneous pulmonary metastasis. Clin Exp Metastasis. 2005; 22(4):319-29. PMID: 16170668.
      Citations: 106     Fields:    Translation:HumansAnimalsCells
    390. Mehta V, Kang Q, Luo J, He TC, Haydon RC, Mass DP. Characterization of adenovirus-mediated gene transfer in rabbit flexor tendons. J Hand Surg Am. 2005 Jan; 30(1):136-41. PMID: 15680569.
      Citations: 9     Fields:    Translation:AnimalsCells
    391. Luu HH, Zhang R, Haydon RC, Rayburn E, Kang Q, Si W, Park JK, Wang H, Peng Y, Jiang W, He TC. Wnt/beta-catenin signaling pathway as a novel cancer drug target. Curr Cancer Drug Targets. 2004 Dec; 4(8):653-71. PMID: 15578921.
      Citations: 106     Fields:    Translation:HumansAnimalsCells
    392. Luo Q, Kang Q, Si W, Jiang W, Park JK, Peng Y, Li X, Luu HH, Luo J, Montag AG, Haydon RC, He TC. Connective tissue growth factor (CTGF) is regulated by Wnt and bone morphogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells. J Biol Chem. 2004 Dec 31; 279(53):55958-68. PMID: 15496414.
      Citations: 156     Fields:    Translation:HumansAnimalsCells
    393. Peng Y, Kang Q, Luo Q, Jiang W, Si W, Liu BA, Luu HH, Park JK, Li X, Luo J, Montag AG, Haydon RC, He TC. Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells. J Biol Chem. 2004 Jul 30; 279(31):32941-9. PMID: 15161906.
      Citations: 115     Fields:    Translation:AnimalsCells
    394. He TC. Adenoviral vectors. Curr Protoc Hum Genet. 2004 May; Chapter 12:Unit 12.4. PMID: 18428355.
      Citations: 13     Fields:    Translation:HumansCells
    395. Haydon RC, Zhou L, He TC. Tyrosine kinase inhibitor STI-571: the new wonder drug of cancer therapy. Cancer Biol Ther. 2004 Apr; 3(4):393-4. PMID: 15004535.
      Citations: 1     Fields:    Translation:Humans
    396. Park JY, Luo Q, Jiang W, Kang Q, Peng Y, Strom C, Luu HH, Haydon RC, He TC. Dual regulation of gene expression mediated by tetracycline and Cre recombinase. Biotechniques. 2004 Mar; 36(3):390-2, 394, 396. PMID: 15038152.
      Citations: 3     Fields:    Translation:HumansCells
    397. Peng Y, Kang Q, Cheng H, Li X, Sun MH, Jiang W, Luu HH, Park JY, Haydon RC, He TC. Transcriptional characterization of bone morphogenetic proteins (BMPs)-mediated osteogenic signaling. J Cell Biochem. 2003 Dec 15; 90(6):1149-65. PMID: 14635189.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    398. Deyrup AT, Haydon RC, Huo D, Ishikawa A, Peabody TD, He TC, Montag AG. Myoid differentiation and prognosis in adult pleomorphic sarcomas of the extremity: an analysis of 92 cases. Cancer. 2003 Aug 15; 98(4):805-13. PMID: 12910526.
      Citations: 10     Fields:    Translation:Humans
    399. Tang N, Huang AL, Zhang BQ, Yan G, He TC. [Potent and specific inhibition of hepatitis B virus antigen expression by RNA interference]. Zhonghua Yi Xue Za Zhi. 2003 Aug 10; 83(15):1309-12. PMID: 12930684.
      Citations: 4     Fields:    Translation:HumansCells
    400. Cheng H, Jiang W, Phillips FM, Haydon RC, Peng Y, Zhou L, Luu HH, An N, Breyer B, Vanichakarn P, Szatkowski JP, Park JY, He TC. Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs). J Bone Joint Surg Am. 2003 Aug; 85(8):1544-52. PMID: 12925636.
      Citations: 325     Fields:    Translation:HumansAnimalsCells
    401. Xiang MQ, Huang AL, Tang N, Xiao YJ, Yan G, He TC. [The expression of Recombinant adenovirus IkappaBalphaM in human hepatocarcinoma HepG2 and it's inhibitive effect to the activity of NF-kappaB]. Zhonghua Yi Xue Za Zhi. 2003 Jul 10; 83(13):1156-60. PMID: 12921635.
      Citations:    Fields:    Translation:HumansCells
    402. Zhou L, An N, Haydon RC, Zhou Q, Cheng H, Peng Y, Jiang W, Luu HH, Vanichakarn P, Szatkowski JP, Park JY, Breyer B, He TC. Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the beta-catenin signaling activity. Cancer Lett. 2003 Apr 25; 193(2):161-70. PMID: 12706873; PMCID: PMC4527752.
      Citations: 26     Fields:    Translation:HumansCells
    403. Paul R, Haydon RC, Cheng H, Ishikawa A, Nenadovich N, Jiang W, Zhou L, Breyer B, Feng T, Gupta P, He TC, Phillips FM. Potential use of Sox9 gene therapy for intervertebral degenerative disc disease. Spine (Phila Pa 1976). 2003 Apr 15; 28(8):755-63. PMID: 12698117; PMCID: PMC4123440.
      Citations: 75     Fields:    Translation:HumansAnimalsCells
    404. Haydon RC, Deyrup A, Ishikawa A, Heck R, Jiang W, Zhou L, Feng T, King D, Cheng H, Breyer B, Peabody T, Simon MA, Montag AG, He TC. Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma. Int J Cancer. 2002 Dec 01; 102(4):338-42. PMID: 12402302; PMCID: PMC4122310.
      Citations: 78     Fields:    Translation:HumansCells
    405. Wang HL, Wang J, Xiao SY, Haydon R, Stoiber D, He TC, Bissonnette M, Hart J. Elevated protein expression of cyclin D1 and Fra-1 but decreased expression of c-Myc in human colorectal adenocarcinomas overexpressing beta-catenin. Int J Cancer. 2002 Oct 01; 101(4):301-10. PMID: 12209953.
      Citations: 18     Fields:    Translation:HumansCells
    406. Haydon RC, Zhou L, Feng T, Breyer B, Cheng H, Jiang W, Ishikawa A, Peabody T, Montag A, Simon MA, He TC. Nuclear receptor agonists as potential differentiation therapy agents for human osteosarcoma. Clin Cancer Res. 2002 May; 8(5):1288-94. PMID: 12006550; PMCID: PMC4527755.
      Citations: 44     Fields:    Translation:HumansCells
    407. Shih IM, Yu J, He TC, Vogelstein B, Kinzler KW. The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression. Cancer Res. 2000 Mar 15; 60(6):1671-6. PMID: 10749138.
      Citations: 33     Fields:    Translation:HumansCells
    408. He TC, Chan TA, Vogelstein B, Kinzler KW. PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell. 1999 Oct 29; 99(3):335-45. PMID: 10555149; PMCID: PMC3779681.
      Citations: 305     Fields:    Translation:HumansCells
    409. da Costa LT, He TC, Yu J, Sparks AB, Morin PJ, Polyak K, Laken S, Vogelstein B, Kinzler KW. CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling. Oncogene. 1999 Sep 02; 18(35):5010-4. PMID: 10490837.
      Citations: 48     Fields:    Translation:HumansCells
    410. He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, Morin PJ, Vogelstein B, Kinzler KW. Identification of c-MYC as a target of the APC pathway. Science. 1998 Sep 04; 281(5382):1509-12. PMID: 9727977.
      Citations: 1703     Fields:    Translation:HumansCells
    411. He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, Vogelstein B. A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci U S A. 1998 Mar 03; 95(5):2509-14. PMID: 9482916; PMCID: PMC19394.
      Citations: 1277     Fields:    Translation:HumansAnimalsCells
    412. Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, Thiagalingam S, Kinzler KW, Vogelstein B. 14-3-3sigma is a p53-regulated inhibitor of G2/M progression. Mol Cell. 1997 Dec; 1(1):3-11. PMID: 9659898.
      Citations: 349     Fields:    Translation:HumansCells
    413. Polyak K, Waldman T, He TC, Kinzler KW, Vogelstein B. Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev. 1996 Aug 01; 10(15):1945-52. PMID: 8756351.
      Citations: 120     Fields:    Translation:HumansCells
    414. Jiang N, He TC, Miyajima A, Wojchowski DM. The box1 domain of the erythropoietin receptor specifies Janus kinase 2 activation and functions mitogenically within an interleukin 2 beta-receptor chimera. J Biol Chem. 1996 Jul 12; 271(28):16472-6. PMID: 8663338.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    415. Da Costa LT, Jen J, He TC, Chan TA, Kinzler KW, Vogelstein B. Converting cancer genes into killer genes. Proc Natl Acad Sci U S A. 1996 Apr 30; 93(9):4192-6. PMID: 8633039; PMCID: PMC39510.
      Citations: 4     Fields:    Translation:HumansCells
    416. Zhuang H, Niu Z, He TC, Patel SV, Wojchowski DM. Erythropoietin-dependent inhibition of apoptosis is supported by carboxyl-truncated receptor forms and blocked by dominant-negative forms of Jak2. J Biol Chem. 1995 Jun 16; 270(24):14500-4. PMID: 7782312.
      Citations: 10     Fields:    Translation:AnimalsCells
    417. He TC, Jiang N, Zhuang H, Wojchowski DM. Erythropoietin-induced recruitment of Shc via a receptor phosphotyrosine-independent, Jak2-associated pathway. J Biol Chem. 1995 May 12; 270(19):11055-61. PMID: 7538110.
      Citations: 11     Fields:    Translation:AnimalsCells
    418. Zhuang H, Patel SV, He TC, Niu Z, Wojchowski DM. Dominant negative effects of a carboxy-truncated Jak2 mutant on Epo-induced proliferation and Jak2 activation. Biochem Biophys Res Commun. 1994 Oct 14; 204(1):278-83. PMID: 7945371.
      Citations: 3     Fields:    Translation:AnimalsCells
    419. Zhuang H, Patel SV, He TC, Sonsteby SK, Niu Z, Wojchowski DM. Inhibition of erythropoietin-induced mitogenesis by a kinase-deficient form of Jak2. J Biol Chem. 1994 Aug 26; 269(34):21411-4. PMID: 8063772.
      Citations: 18     Fields:    Translation:AnimalsCells
    420. He TC, Jiang N, Zhuang H, Quelle DE, Wojchowski DM. The extended box 2 subdomain of erythropoietin receptor is nonessential for Jak2 activation yet critical for efficient mitogenesis in FDC-ER cells. J Biol Chem. 1994 Jul 15; 269(28):18291-4. PMID: 8034573.
      Citations: 9     Fields:    Translation:AnimalsCells
    421. He TC, Zhuang H, Jiang N, Waterfield MD, Wojchowski DM. Association of the p85 regulatory subunit of phosphatidylinositol 3-kinase with an essential erythropoietin receptor subdomain. Blood. 1993 Dec 15; 82(12):3530-8. PMID: 7505116.
      Citations: 23     Fields:    Translation:AnimalsCells
    422. Wojchowski DM, He TC. Signal transduction in the erythropoietin receptor system. Stem Cells. 1993 Sep; 11(5):381-92. PMID: 8241949.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
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