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Maneesh Misra

TitleAssistant Professor
InstitutionUniversity of Chicago
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    Dr. Maneesh Kumar Misra, MS, PhD, F(ACHI) is an Associate Medical Director of Transplant Immunology and Immunogenetics Section, and the Assistant Professor of Clinical Pathology. He is certified by the American College of Histocompatibility and Immunogenetics. His research and scholarly interests include allogeneic transplantation, autoimmunity, hematopoietic stem cell transplantation, immunogenetics, and solid organ transplantation. His research mainly focuses on the detection and functional characterization of alloantibodies in the setting of clinical allogenic transplantation. He has identified and characterized several novel HLA alleles, authored more than 20 peer-reviewed publications, and coauthored a book. Maneesh received his PhD from Banaras Hindu University Institute of Medical Sciences in India, and subsequently held research positions at the Sanjay Gandhi Postgraduate Institute of Medical Sciences. He then completed a postdoctoral fellowship at the University of California, San Francisco School of Medicine, and an American Society for Histocompatibility and Immunogenetics approved Director-in-training clinical fellowship in transplant immunology and immunogenetics at the University of Chicago Pritzker School of Medicine.

    Collapse Biography 
    Collapse education and training
    The University of Chicago Medicine, Chicago, IL, USAClinical Fellowship08/2020Transplant Immunology and Immunogenetics
    University of California San Francisco School of Medicine, San Francisco, CA, USAPostdoctoral Fellowship09/2018Immunology and Immunogenetics
    Banaras Hindu University, Institute of Medical Sciences, Varanasi, UP, IndiaPh.D.05/2015Transplant Immunology and Immunogenetics
    Collapse awards and honors
    2017Best Poster Award in Most Innovative Research Category, American Society for Histocompatibility and Immunogenetics
    2018Readers' Choice: The Best Paper of Genes and Immunity, Genes and Immunity Journal
    2018Immunology Review Honorarium, British Society for Immunology
    2019CAP/BSD Travel Award, University of Chicago

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Misra MK, Brown NK, Marino SG. Next-generation sequencing identifies two novel HLA-DPB1 alleles: HLA-DPB1*1069:01 and DPB1*1072:01. HLA. 2024 Feb; 103(2):e15368. PMID: 38342772.
      Citations:    Fields:    Translation:Humans
    2. Mishra AK, Mumtaz N, Misra MK. Identification of Candidate mRNA Genes and Their Potential MicroRNA Targets in Lung Cancer Induced by Smoking Tobacco. Front Biosci (Schol Ed). 2023 11 27; 15(4):13. PMID: 38163953.
      Citations:    Fields:    Translation:Humans
    3. Montero-Martin G, Kichula KM, Misra MK, de Brito Vargas L, Marin WM, Hollenbach JA, Fernández-Viña MA, Elfishawi S, Norman PJ. Exceptional diversity of KIR and HLA class I in Egypt. HLA. 2024 Jan; 103(1):e15177. PMID: 37528739; PMCID: PMC11068459.
      Citations:    Fields:    Translation:Humans
    4. Misra MK, Weidner JG, Upchurch RL, Mankey AM, Marino SG, Fernandez-Viña MA. Spherotech-EDTA combined serum treatment reduces background more effectively as compared to One Lambda Adsorb Out™ and LIFECODES Serum Cleaner in Luminex-based solid-phase immunoassays for HLA antibody detection. HLA. 2023 Aug; 102(2):147-156. PMID: 36961354.
      Citations:    Fields:    
    5. Didonna A, Damotte V, Shams H, Matsunaga A, Caillier SJ, Dandekar R, Misra MK, Mofrad MRK, Oksenberg JR, Hollenbach JA. A splice acceptor variant in HLA-DRA affects the conformation and cellular localization of the class II DR alpha-chain. Immunology. 2021 02; 162(2):194-207. PMID: 32986852; PMCID: PMC7808164.
      Citations: 3     Fields:    Translation:HumansCells
    6. Holzhauser L, Misra MK, Miller T, Kalantari S, Smith B, Nguyen A, Chung B, Sarswat N, Kim G, Marino S, Grinstein J. HLA Matching in Cardiac Transplantation - Impact on Cardiac Allograft Vasculopathy, Rejection and Donor Specific Antibodies. Journal of Cardiac Failure. 2020; 26(10):S157. View Publication.
    7. Misra MK, Xin JJ, Brown NK, Weidner JG, Upchurch RL, Bishop MR, Wool GD, Artz AS, Marino SR. Effective desensitization for a strong donor-specific HLA antibody in a case of HLA-mismatched allogeneic hematopoietic cell transplantation. HLA. 2019 09; 94(3):307-311. PMID: 31314169.
      Citations: 1     Fields:    Translation:Humans
    8. Hollenbach JA, Norman PJ, Creary LE, Damotte V, Montero-Martin G, Caillier S, Anderson KM, Misra MK, Nemat-Gorgani N, Osoegawa K, Santaniello A, Renschen A, Marin WM, Dandekar R, Parham P, Tanner CM, Hauser SL, Oksenberg JR, Fernandez-Viña M. A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson's disease. Proc Natl Acad Sci U S A. 2019 04 09; 116(15):7419-7424. PMID: 30910980; PMCID: PMC6462083.
      Citations: 32     Fields:    Translation:HumansCellsCTClinical Trials
    9. Misra MK, Martin GM, Nemat-Gorgani N, Traherne JA, Bultitude WP, Marin W, Vierra-Green C, Anderson KM, Caro-Oleas JL, Colucci F, Dandekar R, Elfishawi SM, Fouda M, Herrero-Mata MJ, Hollenbach SQ, Marsh SGE, Mentzer A, Middleton D, Moffett A, Mossallam GI, Nakimuli A, Oksenberg JR, Oppenheimer SJ, Parham P, Trowsdale J, Vilches C, Norman PJ, Hollenbach JA, Augusto DG, Sauter J, Hofmann JA, González-Quezada B, Gorodezky C, Balas A, Cisneros E, Fernández-Viña MA, González-Fernández R, Große A, Moreno-Hidalgo MA, Petzl-Erler ML, Planelles D, Sánchez-García F, Sánchez-Gordo F, Schmidt AH, Vargas LB, Vicario JL. Report from the Killer-cell Immunoglobulin-like Receptors (KIR) component of the 17th International HLA and Immunogenetics Workshop. Hum Immunol. 2018 Dec; 79(12):825-833. PMID: 30321631; PMCID: PMC6322681.
      Citations: 13     Fields:    Translation:Humans
    10. Misra MK, Damotte V, Hollenbach JA. Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis. Genes Immun. 2019 01; 20(1):46-55. PMID: 29362509; PMCID: PMC6054566.
      Citations: 3     Fields:    Translation:HumansCells
    11. Misra MK, Damotte V, Hollenbach JA. The immunogenetics of neurological disease. Immunology. 2018 04; 153(4):399-414. PMID: 29159928; PMCID: PMC5838423.
      Citations: 29     Fields:    Translation:HumansAnimals
    12. Prakash S, Misra MK, Agrawal S. Non-Classical Human Leukocyte Antigen-G Allelic Diversity Among North Indians. Anthropology Journal. 2016; 2(1):27-35. View Publication.
    13. Misra MK, Singh B, Mishra A, Agrawal S. Co-stimulatory CD28 and transcription factor NFKB1 gene variants affect idiopathic recurrent miscarriages. J Hum Genet. 2016 Dec; 61(12):1035-1041. PMID: 27488439.
      Citations: 2     Fields:    Translation:Humans
    14. Misra MK, Mishra A, Phadke SR, Agrawal S. Association of functional genetic variants of CTLA4 with reduced serum CTLA4 protein levels and increased risk of idiopathic recurrent miscarriages. Fertil Steril. 2016 Oct; 106(5):1115-1123.e6. PMID: 27351445.
      Citations: 12     Fields:    Translation:HumansCells
    15. Misra MK, Mishra A, Pandey SK, Kapoor R, Sharma RK, Agrawal S. Association of functional genetic variants of transcription factor Forkhead Box P3 and Nuclear Factor-?B with end-stage renal disease and renal allograft outcome. Gene. 2016 Apr 25; 581(1):57-65. PMID: 26794449.
      Citations: 12     Fields:    Translation:Humans
    16. Misra MK, Prakash S, Moulik NR, Kumar A, Agrawal S. Genetic associations of killer immunoglobulin like receptors and class I human leukocyte antigens on childhood acute lymphoblastic leukemia among north Indians. Hum Immunol. 2016 Jan; 77(1):41-46. PMID: 26472014.
      Citations: 12     Fields:    Translation:HumansCells
    17. Misra MK, Mishra A, Pandey SK, Kapoor R, Sharma RK, Agrawal S. Genetic variation in Micro-RNA genes of host genome affects clinical manifestation of symptomatic Human Cytomegalovirus infection. Hum Immunol. 2015 Oct; 76(10):765-9. PMID: 26429309.
      Citations: 6     Fields:    Translation:HumansCells
    18. Misra MK, Pandey SK, Kapoor R, Sharma RK, Agrawal S. Cytotoxic T-lymphocyte antigen 4 gene polymorphism influences the incidence of symptomatic human cytomegalovirus infection after renal transplantation. Pharmacogenet Genomics. 2015 Jan; 25(1):19-29. PMID: 25356901.
      Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
    19. Misra MK, Mishra A. Wireless Technology in Health prospective. Lap Lambert Academic Publishing, Germany. 2014; 1-68. View Publication.
    20. Saxena D, Misra MK, Parveen F, Phadke SR, Agrawal S. The transcription factor Forkhead Box P3 gene variants affect idiopathic recurrent pregnancy loss. Placenta. 2015 Feb; 36(2):226-31. PMID: 25499308.
      Citations: 18     Fields:    Translation:Humans
    21. Agrawal D, Prakash S, Misra MK, Phadke SR, Agrawal S. Implication of HLA-G 5' upstream regulatory region polymorphisms in idiopathic recurrent spontaneous abortions. Reprod Biomed Online. 2015 Jan; 30(1):82-91. PMID: 25457193.
      Citations: 6     Fields:    Translation:Humans
    22. Misra MK, Pandey SK, Kapoor R, Sharma RK, Agrawal S. Genetic variants of MicroRNA-related genes in susceptibility and prognosis of end-stage renal disease and renal allograft outcome among north Indians. Pharmacogenet Genomics. 2014 Sep; 24(9):442-50. PMID: 24978643.
      Citations: 8     Fields:    Translation:Humans
    23. Siddesh A, Parveen F, Misra MK, Phadke SR, Agrawal S. Platelet-specific collagen receptor glycoprotein VI gene variants affect recurrent pregnancy loss. Fertil Steril. 2014 Oct; 102(4):1078-1084.e3. PMID: 25086789.
      Citations: 3     Fields:    Translation:Humans
    24. Misra MK, Pandey SK, Kapoor R, Sharma RK, Kapoor R, Prakash S, Agrawal S. HLA-G gene expression influenced at allelic level in association with end stage renal disease and acute allograft rejection. Hum Immunol. 2014 Aug; 75(8):833-9. PMID: 24929145.
      Citations: 8     Fields:    Translation:HumansCells
    25. Misra MK, Kapoor R, Pandey SK, Sharma RK, Agrawal S. Association of CTLA-4 gene polymorphism with end-stage renal disease and renal allograft outcome. J Interferon Cytokine Res. 2014 Mar; 34(3):148-61. PMID: 24313821.
      Citations: 12     Fields:    Translation:HumansCells
    26. Misra MK, Prakash S, Kapoor R, Pandey SK, Sharma RK, Agrawal S. Association of HLA-G promoter and 14-bp insertion-deletion variants with acute allograft rejection and end-stage renal disease. Tissue Antigens. 2013 Nov; 82(5):317-26. PMID: 24131018.
      Citations: 12     Fields:    Translation:HumansCells
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