Theca Cells
"Theca Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The flattened stroma cells forming a sheath or theca outside the basal lamina lining the mature OVARIAN FOLLICLE. Thecal interstitial or stromal cells are steroidogenic, and produce primarily ANDROGENS which serve as precusors of ESTROGENS in the GRANULOSA CELLS.
Descriptor ID |
D013799
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MeSH Number(s) |
A05.360.319.114.630.535.400 A06.407.312.497.535.600 A11.329.850
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Concept/Terms |
Theca Cells- Theca Cells
- Cell, Theca
- Cells, Theca
- Theca Cell
- Ovarian Interstitial Cells
- Cell, Ovarian Interstitial
- Cells, Ovarian Interstitial
- Interstitial Cell, Ovarian
- Interstitial Cells, Ovarian
- Ovarian Interstitial Cell
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Below are MeSH descriptors whose meaning is more general than "Theca Cells".
Below are MeSH descriptors whose meaning is more specific than "Theca Cells".
This graph shows the total number of publications written about "Theca Cells" by people in this website by year, and whether "Theca Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1988 | 1 | 1 | 2 | 1990 | 1 | 1 | 2 | 1997 | 0 | 1 | 1 | 1998 | 0 | 1 | 1 | 2001 | 1 | 0 | 1 | 2009 | 0 | 1 | 1 | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Theca Cells" by people in Profiles.
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Chugh RM, Park HS, Esfandyari S, Elsharoud A, Ulin M, Al-Hendy A. Mesenchymal Stem Cell-Conditioned Media Regulate Steroidogenesis and Inhibit Androgen Secretion in a PCOS Cell Model via BMP-2. Int J Mol Sci. 2021 Aug 25; 22(17).
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Hirshfeld-Cytron J, Barnes RB, Ehrmann DA, Caruso A, Mortensen MM, Rosenfield RL. Characterization of functionally typical and atypical types of polycystic ovary syndrome. J Clin Endocrinol Metab. 2009 May; 94(5):1587-94.
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Nelson VL, Qin KN, Rosenfield RL, Wood JR, Penning TM, Legro RS, Strauss JF, McAllister JM. The biochemical basis for increased testosterone production in theca cells propagated from patients with polycystic ovary syndrome. J Clin Endocrinol Metab. 2001 Dec; 86(12):5925-33.
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Barnes RB. The pathogenesis of polycystic ovary syndrome: lessons from ovarian stimulation studies. J Endocrinol Invest. 1998 Oct; 21(9):567-79.
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Rosenfield RL. Current concepts of polycystic ovary syndrome. Baillieres Clin Obstet Gynaecol. 1997 Jun; 11(2):307-33.
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Cara JF, Fan J, Azzarello J, Rosenfield RL. Insulin-like growth factor-I enhances luteinizing hormone binding to rat ovarian theca-interstitial cells. J Clin Invest. 1990 Aug; 86(2):560-5.
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Rosenfield RL, Barnes RB, Cara JF, Lucky AW. Dysregulation of cytochrome P450c 17 alpha as the cause of polycystic ovarian syndrome. Fertil Steril. 1990 May; 53(5):785-91.
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Cara JF, Rosenfield RL. Insulin-like growth factor I and insulin potentiate luteinizing hormone-induced androgen synthesis by rat ovarian thecal-interstitial cells. Endocrinology. 1988 Aug; 123(2):733-9.
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Stamp GW, Krausz T. Fine needle aspiration cytology of a recurrent juvenile granulosa cell tumor. Acta Cytol. 1988 Jul-Aug; 32(4):533-9.
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