Loading...
The University of Chicago Header Logo
Keywords
Last Name
Institution

Jessica Kandel

TitleProfessor
InstitutionUniversity of Chicago
DepartmentSurgery-Pediatric
AddressChicago IL 60637
vCardDownload vCard

    Collapse Overview 

    Collapse Biography 
    Collapse education and training
    Yale University, New Haven, CTBA05/1981Medieval Studies
    Columbia University, New York, NYMD5/1985Medicine
    Massachusetts General Hospital, Boston, MA06/1989Surgical residency (PGY 1-3)
    Boston Children's Hospital, Boston, MA06/1991Surgical research
    Massachusetts General Hospital, Boston, MA06/1993Surgical residency (PGY 4-5)
    Johns Hopkins Hospital, Baltimore, MD06/1995Pediatric Surgery Fellowship
    Collapse awards and honors
    1977Presidential Scholar, United States Presidential Scholars Program
    1981Phi Beta Kappa, Yale University
    1985NIH Training Grant, National Institutes of Health
    1985Upjohn Award for Excellence in Research, Columbia University
    1989 - 1991Marshal K. Bartlett Fellowship Award, Massachusetts General Hospital
    1999Peter Paul Rickham Prize, British Association of Paediatric Surgeons
    2001Irving Scholar Award, Columbia University
    2002Kyushu University Visiting Professorship, Kyushu University, Japan
    2003Doctor Harold and Golden Lamport Award for Excellence in Basic Science Research, Columbia University
    2003Schullinger Lectureship in Pediatric Cancer, Columbia University
    2004Institute for Cancer Genetics, Associate Professorship, Columbia University
    2008Elected, American Surgical Association
    2009R. Peter Altman Chair in Surgery, Columbia University
    2013Mary Campau Ryerson Chair in Surgery, University of Chicago
    2013Master Clinician, Bucksbaum Institute for Clinical Excellence, University of Chicago
    2014 - 2019Faculty Teaching Award, Department of Surgery, University of Chicago

    Collapse Research 
    Collapse research activities and funding
         (Jessica Kandel)Jul 1, 1997 - Dec 31, 2022
    Pediatric Cancer Foundation
    Studies in pediatric tumor angiogenesis
    Role Description: Our goal is to understand the role that abnormal functions and development of vasculature play in promoting tumor growth and metastasis.
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Mak GZ, Kandel JJ. Editorial: Changing paradigms in pediatric surgery. Curr Opin Pediatr. 2019 Jun; 31(3):367. PMID: 31090578.
      View in: PubMed
    2. Hernandez SL, Nelson M, Sampedro GR, Bagrodia N, Defnet AM, Lec B, Emolo J, Kirschner R, Wu L, Biermann H, Shen S, Bubeck Wardenburg J, Kandel JJ. Staphylococcus aureus alpha toxin activates Notch in vascular cells. Angiogenesis. 2019 02; 22(1):197-209. PMID: 30324336.
      View in: PubMed
    3. Linden AF, Raiji MT, Kohler JE, Carlisle EM, Pelayo JC, Feinstein K, Kandel JJ, Mak GZ. Evaluation of a water-soluble contrast protocol for nonoperative management of pediatric adhesive small bowel obstruction. J Pediatr Surg. 2019 Jan; 54(1):184-188. PMID: 30414689.
      View in: PubMed
    4. Boboila S, Lopez G, Yu J, Banerjee D, Kadenhe-Chiweshe A, Connolly EP, Kandel JJ, Rajbhandari P, Silva JM, Califano A, Yamashiro DJ. Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma. Oncogene. 2018 10; 37(40):5451-5465. PMID: 29880876.
      View in: PubMed
    5. Shakhsheer BA, Lec B, Zaborin A, Guyton K, Defnet AM, Bagrodia N, Kandel JJ, Zaborina O, Hernandez SL, Alverdy J. Lack of evidence for tissue hypoxia as a contributing factor in anastomotic leak following colon anastomosis and segmental devascularization in rats. Int J Colorectal Dis. 2017 Apr; 32(4):539-547. PMID: 27999936.
      View in: PubMed
    6. Wu JK, Hooper ED, Laifer-Narin SL, Simpson LL, Kandel J, Shawber CJ. Initial Experience With Propranolol Treatment of Lymphatic Anomalies: A Case Series. Pediatrics. 2016 09; 138(3). PMID: 27561730.
      View in: PubMed
    7. Ehrlich PF, Hamilton TE, Gow K, Barnhart D, Ferrer F, Kandel J, Glick R, Dasgupta R, Naranjo A, He Y, Perlman EJ, Kalapurakal JA, Khanna G, Dome JS, Geller J, Mullen E. Surgical protocol violations in children with renal tumors provides an opportunity to improve pediatric cancer care: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2016 11; 63(11):1905-10. PMID: 27229358.
      View in: PubMed
    8. Defnet AM, Bagrodia N, Hernandez SL, Gwilliam N, Kandel JJ. Pediatric lymphatic malformations: evolving understanding and therapeutic options. Pediatr Surg Int. 2016 May; 32(5):425-33. PMID: 26815877.
      View in: PubMed
    9. Geyer MB, Radhakrishnan K, Giller R, Umegaki N, Harel S, Kiuru M, Morel KD, LeBoeuf N, Kandel J, Bruckner A, Fabricatore S, Chen M, Woodley D, McGrath J, Baxter-Lowe L, Uitto J, Christiano AM, Cairo MS. Reduced Toxicity Conditioning and Allogeneic Hematopoietic Progenitor Cell Transplantation for Recessive Dystrophic Epidermolysis Bullosa. J Pediatr. 2015 Sep; 167(3):765-9.e1. PMID: 26148662.
      View in: PubMed
    10. Bagrodia N, Defnet AM, Kandel JJ. Management of lymphatic malformations in children. Curr Opin Pediatr. 2015 Jun; 27(3):356-63. PMID: 25888145.
      View in: PubMed
    11. Nolan TL, Kandel JJ, Nakayama DK. Quality and extent of locum tenens coverage in pediatric surgical practices. Am Surg. 2015 Apr; 81(4):377-80. PMID: 25831184.
      View in: PubMed
    12. Banerjee D, Hernandez SL, Garcia A, Kangsamaksin T, Sbiroli E, Andrews J, Forrester LA, Wei N, Kadenhe-Chiweshe A, Shawber CJ, Kitajewski JK, Kandel JJ, Yamashiro DJ. Notch suppresses angiogenesis and progression of hepatic metastases. Cancer Res. 2015 Apr 15; 75(8):1592-602. PMID: 25744722.
      View in: PubMed
    13. Wu JK, Kitajewski C, Reiley M, Keung CH, Monteagudo J, Andrews JP, Liou P, Thirumoorthi A, Wong A, Kandel JJ, Shawber CJ. Aberrant lymphatic endothelial progenitors in lymphatic malformation development. PLoS One. 2015; 10(2):e0117352. PMID: 25719418.
      View in: PubMed
    14. Rothstein DH, Kandel JJ. Pediatric surgical transitional care. Preface. Semin Pediatr Surg. 2015 Apr; 24(2):59-60. PMID: 25770363.
      View in: PubMed
    15. Weitz NA, Lauren CT, Behr GG, Wu JK, Kandel JJ, Meyers PM, Sultan S, Anyane-Yeboa K, Morel KD, Garzon MC. Clinical spectrum of capillary malformation-arteriovenous malformation syndrome presenting to a pediatric dermatology practice: a retrospective study. Pediatr Dermatol. 2015 Jan-Feb; 32(1):76-84. PMID: 25040287.
      View in: PubMed
    16. Aspelund G, Fingeret A, Gross E, Kessler D, Keung C, Thirumoorthi A, Oh PS, Behr G, Chen S, Lampl B, Middlesworth W, Kandel J, Ruzal-Shapiro C. Ultrasonography/MRI versus CT for diagnosing appendicitis. Pediatrics. 2014 Apr; 133(4):586-93. PMID: 24590746.
      View in: PubMed
    17. Kandel JJ. Serendipity: translational research, high quality care, and the children's hospital. Jay and Margie Grosfeld Lecture. J Pediatr Surg. 2014 Jan; 49(1):19-24. PMID: 24439574.
      View in: PubMed
    18. Hamilton TE, Barnhart D, Gow K, Ferrer F, Kandel J, Glick R, Dasgupta R, Naranjo A, He Y, Gratias E, Geller J, Mullen E, Ehrlich P. Inter-rater reliability of surgical reviews for AREN03B2: a COG renal tumor committee study. J Pediatr Surg. 2014 Jan; 49(1):154-8; discussion 158. PMID: 24439601.
      View in: PubMed
    19. Hernandez SL, Banerjee D, Garcia A, Kangsamaksin T, Cheng WY, Anastassiou D, Funahashi Y, Kadenhe-Chiweshe A, Shawber CJ, Kitajewski JK, Kandel JJ, Yamashiro DJ. Notch and VEGF pathways play distinct but complementary roles in tumor angiogenesis. Vasc Cell. 2013 Sep 25; 5(1):17. PMID: 24066611.
      View in: PubMed
    20. Liou P, Bader L, Wang A, Yamashiro D, Kandel JJ. Correlation of tumor-associated macrophages and clinicopathological factors in Wilms tumor. Vasc Cell. 2013 Mar 21; 5(1):5. PMID: 23514200.
      View in: PubMed
    21. Gow KW, Barnhart DC, Hamilton TE, Kandel JJ, Chen MK, Ferrer FA, Price MR, Mullen EA, Geller JI, Gratias EJ, Rosen N, Khanna G, Naranjo A, Ritchey ML, Grundy PE, Dome JS, Ehrlich PF. Primary nephrectomy and intraoperative tumor spill: report from the Children's Oncology Group (COG) renal tumors committee. J Pediatr Surg. 2013 Jan; 48(1):34-8. PMID: 23331790.
      View in: PubMed
    22. Uh MK, Kandel J, Kitajewski J. Evaluating tumor angiogenesis. Methods Mol Biol. 2013; 980:341-51. PMID: 23359165.
      View in: PubMed
    23. Behr GG, Liberman L, Compton J, Garzon MC, Morel KD, Lauren CT, Starc TJ, Kovacs SJ, Beltroni V, Landres R, Anyane-Yeboa K, Meyers PM, Bacha E, Kandel JJ. CM-AVM syndrome in a neonate: case report and treatment with a novel flow reduction strategy. Vasc Cell. 2012 Nov 20; 4(1):19. PMID: 23164092.
      View in: PubMed
    24. Weitz NA, Lauren CT, Starc TJ, Kandel JJ, Bateman DA, Morel KD, Meyers PM, Kadenhe-Chiweshe A, Wu JK, Garzon MC. Congenital cutaneous hemangioma causing cardiac failure: a case report and review of the literature. Pediatr Dermatol. 2013 Nov-Dec; 30(6):e180-90. PMID: 23025620.
      View in: PubMed
    25. Garcia AV, Thirumoorthi AS, Traina JM, Schlossberg P, Sheynzon V, Kandel JJ. Image-guided esophageal anastomosis in esophageal atresia. J Pediatr Surg. 2012 Oct; 47(10):1959-61. PMID: 23084217.
      View in: PubMed
    26. Cheng WY, Kandel JJ, Yamashiro DJ, Canoll P, Anastassiou D. A multi-cancer mesenchymal transition gene expression signature is associated with prolonged time to recurrence in glioblastoma. PLoS One. 2012; 7(4):e34705. PMID: 22493711.
      View in: PubMed
    27. Garcia AV, Fingeret AL, Thirumoorthi AS, Kadenhe-Chiweshe A, Kandel JJ. Severe Mycoplasma pneumoniae infection requiring extracorporeal membrane oxygenation with concomitant ischemic stroke in a child. Pediatr Pulmonol. 2013 Jan; 48(1):98-101. PMID: 22467515.
      View in: PubMed
    28. Sirsi SR, Flexman ML, Vlachos F, Huang J, Hernandez SL, Kim HK, Johung TB, Gander JW, Reichstein AR, Lampl BS, Wang A, Hielscher AH, Kandel JJ, Yamashiro DJ, Borden MA. Contrast ultrasound imaging for identification of early responder tumor models to anti-angiogenic therapy. Ultrasound Med Biol. 2012 Jun; 38(6):1019-29. PMID: 22425376.
      View in: PubMed
    29. Garcia A, Kandel JJ. Notch: a key regulator of tumor angiogenesis and metastasis. Histol Histopathol. 2012 02; 27(2):151-6. PMID: 22207549.
      View in: PubMed
    30. Flexman ML, Vlachos F, Kim HK, Sirsi SR, Huang J, Hernandez SL, Johung TB, Gander JW, Reichstein AR, Lampl BS, Wang A, Borden MA, Yamashiro DJ, Kandel JJ, Hielscher AH. Monitoring early tumor response to drug therapy with diffuse optical tomography. J Biomed Opt. 2012 Jan; 17(1):016014. PMID: 22352664.
      View in: PubMed
    31. Anastassiou D, Rumjantseva V, Cheng W, Huang J, Canoll PD, Yamashiro DJ, Kandel JJ. Human cancer cells express Slug-based epithelial-mesenchymal transition gene expression signature obtained in vivo. BMC Cancer. 2011 Dec 30; 11:529. PMID: 22208948.
      View in: PubMed
    32. Fisher JC, Gander JW, Haley MJ, Hernandez SL, Huang J, Chang YJ, Johung TB, Guarnieri P, O'Toole K, Yamashiro DJ, Kandel JJ. Inhibition of cyclo-oxygenase 2 reduces tumor metastasis and inflammatory signaling during blockade of vascular endothelial growth factor. Vasc Cell. 2011 Oct 06; 3:22. PMID: 21978392.
      View in: PubMed
    33. Sirsi SR, Hernandez SL, Zielinski L, Blomback H, Koubaa A, Synder M, Homma S, Kandel JJ, Yamashiro DJ, Borden MA. Polyplex-microbubble hybrids for ultrasound-guided plasmid DNA delivery to solid tumors. J Control Release. 2012 Jan 30; 157(2):224-34. PMID: 21945680.
      View in: PubMed
    34. Oe Y, Orr L, Laifer-Narin S, Hyodo E, Koczo A, Homma S, Kandel J, Meyers P. Contrast-enhanced sonography as a novel tool for assessment of vascular malformations. J Angiogenes Res. 2010 Nov 22; 2:25. PMID: 21092206.
      View in: PubMed
    35. Kim HK, Flexman M, Yamashiro DJ, Kandel JJ, Hielscher AH. PDE-constrained multispectral imaging of tissue chromophores with the equation of radiative transfer. Biomed Opt Express. 2010 Sep 08; 1(3):812-824. PMID: 21258511.
      View in: PubMed
    36. Boo YJ, Fisher JC, Haley MJ, Cowles RA, Kandel JJ, Yamashiro DJ. Vascular characterization of clear cell sarcoma of the kidney in a child: a case report and review. J Pediatr Surg. 2009 Oct; 44(10):2031-6. PMID: 19853769.
      View in: PubMed
    37. Wan P, Susman J, Kandel J, Jan D, Jerome EH, Parravicini E. Neonatal hepatic mesenchymal hamartoma causing cardiac failure and disseminated intravascular coagulopathy. Am J Perinatol. 2009 Sep; 26(8):601-4. PMID: 19370509.
      View in: PubMed
    38. Zaghloul N, Hernandez SL, Bae JO, Huang J, Fisher JC, Lee A, Kadenhe-Chiweshe A, Kandel JJ, Yamashiro DJ. Vascular endothelial growth factor blockade rapidly elicits alternative proangiogenic pathways in neuroblastoma. Int J Oncol. 2009 Feb; 34(2):401-7. PMID: 19148474.
      View in: PubMed
    39. Huang J, Bae JO, Tsai JP, Kadenhe-Chiweshe A, Papa J, Lee A, Zeng S, Kornfeld ZN, Ullner P, Zaghloul N, Ioffe E, Nandor S, Burova E, Holash J, Thurston G, Rudge J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. Angiopoietin-1/Tie-2 activation contributes to vascular survival and tumor growth during VEGF blockade. Int J Oncol. 2009 Jan; 34(1):79-87. PMID: 19082480.
      View in: PubMed
    40. Funahashi Y, Hernandez SL, Das I, Ahn A, Huang J, Vorontchikhina M, Sharma A, Kanamaru E, Borisenko V, Desilva DM, Suzuki A, Wang X, Shawber CJ, Kandel JJ, Yamashiro DJ, Kitajewski J. A notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis. Cancer Res. 2008 Jun 15; 68(12):4727-35. PMID: 18559519.
      View in: PubMed
    41. Glade Bender JL, Adamson PC, Reid JM, Xu L, Baruchel S, Shaked Y, Kerbel RS, Cooney-Qualter EM, Stempak D, Chen HX, Nelson MD, Krailo MD, Ingle AM, Blaney SM, Kandel JJ, Yamashiro DJ. Phase I trial and pharmacokinetic study of bevacizumab in pediatric patients with refractory solid tumors: a Children's Oncology Group Study. J Clin Oncol. 2008 Jan 20; 26(3):399-405. PMID: 18202416.
      View in: PubMed
    42. Kadenhe-Chiweshe A, Papa J, McCrudden KW, Frischer J, Bae JO, Huang J, Fisher J, Lefkowitch JH, Feirt N, Rudge J, Holash J, Yancopoulos GD, Kandel JJ, Yamashiro DJ. Sustained VEGF blockade results in microenvironmental sequestration of VEGF by tumors and persistent VEGF receptor-2 activation. Mol Cancer Res. 2008 Jan; 6(1):1-9. PMID: 18234958.
      View in: PubMed
    43. Cowles RA, Gewanter RM, Kandel JJ. Ovarian repositioning in pediatric cancer patients: Flexible techniques accommodate pelvic radiation fields. Pediatr Blood Cancer. 2007 Sep; 49(3):339-41. PMID: 16261563.
      View in: PubMed
    44. Nord KM, Kandel J, Lefkowitch JH, Lobritto SJ, Morel KD, North PE, Garzon MC. Multiple cutaneous infantile hemangiomas associated with hepatic angiosarcoma: case report and review of the literature. Pediatrics. 2006 Sep; 118(3):e907-13. PMID: 16880251.
      View in: PubMed
    45. Lee A, Frischer J, Serur A, Huang J, Bae JO, Kornfield ZN, Eljuga L, Shawber CJ, Feirt N, Mansukhani M, Stempak D, Baruchel S, Glade Bender J, Kandel JJ, Yamashiro DJ. Inhibition of cyclooxygenase-2 disrupts tumor vascular mural cell recruitment and survival signaling. Cancer Res. 2006 Apr 15; 66(8):4378-84. PMID: 16618763.
      View in: PubMed
    46. Cowles RA, Stolar CJ, Kandel JJ, Weintraub JL, Susman J, Spigland NA. Preoperative angiography with embolization and radiofrequency ablation as novel adjuncts to safe surgical resection of a large, vascular sacrococcygeal teratoma. Pediatr Surg Int. 2006 Jun; 22(6):554-6. PMID: 16479404.
      View in: PubMed
    47. Yuan E, Li CM, Yamashiro DJ, Kandel J, Thaker H, Murty VV, Tycko B. Genomic profiling maps loss of heterozygosity and defines the timing and stage dependence of epigenetic and genetic events in Wilms' tumors. Mol Cancer Res. 2005 Sep; 3(9):493-502. PMID: 16179496.
      View in: PubMed
    48. Masciotti J, Abdoulaev G, Provenzano F, Hur J, Papa J, Bae J, Huang J, Yamashiro D, Kandel J, Hielscher A. Optical Tomographic and Magnetic Resonance Imaging of Tumor Growth and Regression in Mice treated with VEGF Blockade. Conf Proc IEEE Eng Med Biol Soc. 2005; 1:205-8. PMID: 17282148.
      View in: PubMed
    49. Frischer JS, Huang J, Serur A, Kadenhe-Chiweshe A, McCrudden KW, O'Toole K, Holash J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. Effects of potent VEGF blockade on experimental Wilms tumor and its persisting vasculature. Int J Oncol. 2004 Sep; 25(3):549-53. PMID: 15289855.
      View in: PubMed
    50. Glade Bender J, Cooney EM, Kandel JJ, Yamashiro DJ. Vascular remodeling and clinical resistance to antiangiogenic cancer therapy. Drug Resist Updat. 2004 Aug-Oct; 7(4-5):289-300. PMID: 15533766.
      View in: PubMed
    51. Huang J, Frischer JS, New T, Kim ES, Serur A, Lee A, Kadenhe-Chiwishe A, Pollyea DA, Yokoi A, Holash J, Yancopoulos GD, Kandel JJ, Yamashiro DJ. TNP-470 promotes initial vascular sprouting in xenograft tumors. Mol Cancer Ther. 2004 Mar; 3(3):335-43. PMID: 15026554.
      View in: PubMed
    52. Frischer JS, Huang J, Serur A, Kadenhe A, Yamashiro DJ, Kandel JJ. Biomolecular markers and involution of hemangiomas. J Pediatr Surg. 2004 Mar; 39(3):400-4. PMID: 15017560.
      View in: PubMed
    53. Davidoff AM, Kandel JJ. Antiangiogenic therapy for the treatment of pediatric solid malignancies. Semin Pediatr Surg. 2004 Feb; 13(1):53-60. PMID: 14765371.
      View in: PubMed
    54. Huang J, Soffer SZ, Kim ES, McCrudden KW, Huang J, New T, Manley CA, Middlesworth W, O'Toole K, Yamashiro DJ, Kandel JJ. Vascular remodeling marks tumors that recur during chronic suppression of angiogenesis. Mol Cancer Res. 2004 Jan; 2(1):36-42. PMID: 14757844.
      View in: PubMed
    55. Kaicker S, McCrudden KW, Beck L, New T, Huang J, Frischer JS, Serur A, Kadenhe-Chiweshe A, Yokoi A, Kandel JJ, Yamashiro DJ. Thalidomide is anti-angiogenic in a xenograft model of neuroblastoma. Int J Oncol. 2003 Dec; 23(6):1651-5. PMID: 14612937.
      View in: PubMed
    56. Yokoi A, McCrudden KW, Huang J, Kim ES, Soffer SZ, Frischer JS, Serur A, New T, Yuan J, Mansukhani M, O'toole K, Yamashiro DJ, Kandel JJ. Human epidermal growth factor receptor signaling contributes to tumor growth via angiogenesis in her2/neu-expressing experimental Wilms' tumor. J Pediatr Surg. 2003 Nov; 38(11):1569-73. PMID: 14614702.
      View in: PubMed
    57. Yokoi A, McCrudden KW, Huang J, Kim ES, Soffer SZ, Frischer JS, Serur A, New T, Yuan J, Mansukhani M, O'Toole K, Yamashiro DJ, Kandel JJ. Blockade of her2/neu decreases VEGF expression but does not alter HIF-1 distribution in experimental Wilms tumor. Oncol Rep. 2003 Sep-Oct; 10(5):1271-4. PMID: 12883692.
      View in: PubMed
    58. Huang J, Frischer JS, Serur A, Kadenhe A, Yokoi A, McCrudden KW, New T, O'Toole K, Zabski S, Rudge JS, Holash J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. Regression of established tumors and metastases by potent vascular endothelial growth factor blockade. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13):7785-90. PMID: 12805568.
      View in: PubMed
    59. Glade-Bender J, Kandel JJ, Yamashiro DJ. VEGF blocking therapy in the treatment of cancer. Expert Opin Biol Ther. 2003 Apr; 3(2):263-76. PMID: 12662141.
      View in: PubMed
    60. McCrudden KW, Hopkins B, Frischer J, Novikov A, Huang J, Kadenhe A, New T, Yokoi A, Yamashiro DJ, Kandel JJ, Middlesworth W. Anti-VEGF antibody in experimental hepatoblastoma: suppression of tumor growth and altered angiogenesis. J Pediatr Surg. 2003 Mar; 38(3):308-14; discussion 308-14. PMID: 12632340.
      View in: PubMed
    61. Kim ES, Serur A, Huang J, Manley CA, McCrudden KW, Frischer JS, Soffer SZ, Ring L, New T, Zabski S, Rudge JS, Holash J, Yancopoulos GD, Kandel JJ, Yamashiro DJ. Potent VEGF blockade causes regression of coopted vessels in a model of neuroblastoma. Proc Natl Acad Sci U S A. 2002 Aug 20; 99(17):11399-404. PMID: 12177446.
      View in: PubMed
    62. McCrudden KW, Yokoi A, Thosani A, Soffer SZ, Kim ES, Huang J, Manley C, O'toole K, Yamashiro DJ, Kandel JJ, Middlesworth W. Topotecan is anti-angiogenic in experimental hepatoblastoma. J Pediatr Surg. 2002 Jun; 37(6):857-61. PMID: 12037749.
      View in: PubMed
    63. Soffer SZ, Kim E, Huang J, McCrudden K, Yokoi A, Moore JT, Manley C, O'Toole K, Middlesworth W, Stolar C, Yamashiro DJ, Kandel JJ. Resistance of a VEGF-producing tumor to anti-VEGF antibody: unimpeded growth of human rhabdoid tumor xenografts. J Pediatr Surg. 2002 Mar; 37(3):528-32. PMID: 11877682.
      View in: PubMed
    64. Huang J, Soffer SZ, Kim ES, Yokoi A, Moore JT, McCrudden KW, Manley C, Middlesworth W, O'Toole K, Stolar C, Yamashiro DJ, Kandel JJ. p53 accumulation in favorable-histology Wilms tumor is associated with angiogenesis and clinically aggressive disease. J Pediatr Surg. 2002 Mar; 37(3):523-7. PMID: 11877681.
      View in: PubMed
    65. Kim ES, Soffer SZ, Huang J, McCrudden KW, Yokoi A, Manley CA, Middlesworth W, Kandel JJ, Yamashiro DJ. Distinct response of experimental neuroblastoma to combination antiangiogenic strategies. J Pediatr Surg. 2002 Mar; 37(3):518-22. PMID: 11877680.
      View in: PubMed
    66. Soffer SZ, Kim E, Moore JT, Huang J, Yokoi A, Manley C, O'Toole K, Middlesworth W, Stolar C, Yamashiro D, Kandel J. Novel use of an established agent: Topotecan is anti-angiogenic in experimental Wilms tumor. J Pediatr Surg. 2001 Dec; 36(12):1781-4. PMID: 11733906.
      View in: PubMed
    67. Soffer SZ, Moore JT, Kim E, Huang J, Yokoi A, Manley C, O'Toole K, Stolar C, Middlesworth W, Yamashiro DJ, Kandel JJ. Combination antiangiogenic therapy: increased efficacy in a murine model of Wilms tumor. J Pediatr Surg. 2001 Aug; 36(8):1177-81. PMID: 11479851.
      View in: PubMed
    68. Moore J, Lee M, Garzon M, Soffer S, Kim E, Saouaf R, del Toro G, Yamashiro D, Kandel J. Effective therapy of a vascular tumor of infancy with vincristine. J Pediatr Surg. 2001 Aug; 36(8):1273-6. PMID: 11479875.
      View in: PubMed
    69. Huang J, Moore J, Soffer S, Kim E, Rowe D, Manley CA, O'Toole K, Middlesworth W, Stolar C, Yamashiro D, Kandel J. Highly specific antiangiogenic therapy is effective in suppressing growth of experimental Wilms tumors. J Pediatr Surg. 2001 Feb; 36(2):357-61. PMID: 11172434.
      View in: PubMed
    70. Kim E, Moore J, Huang J, Soffer S, Manley CA, O'Toole K, Middlesworth W, Stolar CJ, Kandel JJ, Yamashiro DJ. All angiogenesis is not the same: Distinct patterns of response to antiangiogenic therapy in experimental neuroblastoma and Wilms tumor. J Pediatr Surg. 2001 Feb; 36(2):287-90. PMID: 11172417.
      View in: PubMed
    71. Rowe DH, Huang J, Li J, Manley C, O'Toole KM, Stolar CJ, Yamashiro DJ, Kandel JJ. Suppression of primary tumor growth in a mouse model of human neuroblastoma. J Pediatr Surg. 2000 Jun; 35(6):977-81. PMID: 10873048.
      View in: PubMed
    72. Rowe DH, Huang J, Kayton ML, Thompson R, Troxel A, O'Toole KM, Yamashiro D, Stolar CJ, Kandel JJ. Anti-VEGF antibody suppresses primary tumor growth and metastasis in an experimental model of Wilms' tumor. J Pediatr Surg. 2000 Jan; 35(1):30-2; discussion 32-3. PMID: 10646769.
      View in: PubMed
    73. Schwarz MA, Kandel J, Brett J, Li J, Hayward J, Schwarz RE, Chappey O, Wautier JL, Chabot J, Lo Gerfo P, Stern D. Endothelial-monocyte activating polypeptide II, a novel antitumor cytokine that suppresses primary and metastatic tumor growth and induces apoptosis in growing endothelial cells. J Exp Med. 1999 Aug 02; 190(3):341-54. PMID: 10430623.
      View in: PubMed
    74. Kayton ML, Rowe DH, O'Toole KM, Thompson RB, Schwarz MA, Stolar CJ, Kandel JJ. Metastasis correlates with production of vascular endothelial growth factor in a murine model of human Wilms' tumor. J Pediatr Surg. 1999 May; 34(5):743-7; discussion 747-8. PMID: 10359175.
      View in: PubMed
    75. Rowe DH, Kayton ML, O'Toole KM, Ingram M, Stolar CJ, Kandel JJ. Pathological angiogenesis in a murine model of human Wilms' tumor. J Pediatr Surg. 1999 May; 34(5):676-9. PMID: 10359162.
      View in: PubMed
    76. Marvin MR, Kayton ML, O'Toole KM, Rowe DH, DeRosa C, Kindred A, Trokhan S, Chabot J, Kandel JJ. A metastasizing model of anaplastic human Wilms tumor in the nude mouse. Eur J Pediatr Surg. 1998 Oct; 8(5):295-8. PMID: 9825240.
      View in: PubMed
    77. Thurston GM, Hayden DL, Burrows P, Clark JI, Taret VG, Kandel J, Courogen M, Peetermans JA, Bowen MS, Miller D, Sullivan KM, Storb R, Stern H, Benedek GB. Quasielastic light scattering study of the living human lens as a function of age. Curr Eye Res. 1997 Mar; 16(3):197-207. PMID: 9088735.
      View in: PubMed
    78. Duffy FJ, Seiler JG, Hergrueter CA, Kandel J, Gelberman RH. Intrinsic mitogenic potential of canine flexor tendons. J Hand Surg Br. 1992 Jun; 17(3):275-7. PMID: 1624859.
      View in: PubMed
    79. Kandel J, Bossy-Wetzel E, Radvanyi F, Klagsbrun M, Folkman J, Hanahan D. Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma. Cell. 1991 Sep 20; 66(6):1095-104. PMID: 1717155.
      View in: PubMed
    Kandel's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description
    Physical Neighbors Expand Description
    _