 Leukemia, Lymphocytic, Chronic, B-Cell
"Leukemia, Lymphocytic, Chronic, B-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.
| Descriptor ID |
D015451
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| MeSH Number(s) |
C04.557.337.428.080.125 C15.604.515.560.080.125 C20.683.515.528.080.125
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| Concept/Terms |
Leukemia, Lymphocytic, Chronic, B-Cell- Leukemia, Lymphocytic, Chronic, B-Cell
- Lymphocytic Lymphoma, Diffuse, Well-Differentiated
- Lymphocytic Lymphoma, Well Differentiated
- Lymphocytic Lymphoma, Well-Differentiated
- Lymphocytic Lymphomas, Well-Differentiated
- Lymphoma, Well-Differentiated Lymphocytic
- Lymphomas, Well-Differentiated Lymphocytic
- Well-Differentiated Lymphocytic Lymphoma
- Well-Differentiated Lymphocytic Lymphomas
- Lymphoma, Lymphocytic
- Lymphoma, Lymphocytic, Diffuse, Well Differentiated
- Lymphoma, Lymphocytic, Diffuse, Well-Differentiated
- Lymphoma, Lymphocytic, Well Differentiated
- Chronic Lymphocytic Leukemia
- Chronic Lymphocytic Leukemias
- Leukemia, Chronic Lymphocytic
- Leukemias, Chronic Lymphocytic
- Lymphocytic Leukemias, Chronic
- Diffuse Well-Differentiated Lymphocytic Lymphoma
- Diffuse Well Differentiated Lymphocytic Lymphoma
- Leukemia, B Cell, Chronic
- Leukemia, B-Cell, Chronic
- Leukemia, Lymphoblastic, Chronic
- Leukemia, Lymphocytic, Chronic
- Leukemia, Lymphocytic, Chronic, B Cell
- Lymphoblastic Leukemia, Chronic
- Chronic Lymphoblastic Leukemia
- Chronic Lymphoblastic Leukemias
- Leukemia, Chronic Lymphoblastic
- Leukemias, Chronic Lymphoblastic
- Lymphoblastic Leukemias, Chronic
- Lymphocytic Leukemia, Chronic
- Lymphocytic Leukemia, Chronic, B Cell
- Lymphocytic Leukemia, Chronic, B-Cell
- Lymphocytic Lymphoma
- Lymphocytic Lymphomas
- Lymphomas, Lymphocytic
- Lymphocytic Lymphoma, Diffuse, Well Differentiated
- Lymphoma, Small Lymphocytic
- Lymphocytic Lymphoma, Small
- Lymphocytic Lymphomas, Small
- Lymphomas, Small Lymphocytic
- Small Lymphocytic Lymphoma
- Small Lymphocytic Lymphomas
- Lymphoma, Small Lymphocytic, Plasmacytoid
- Lymphoma, Small-Cell
- Lymphoma, Small Cell
- Lymphomas, Small-Cell
- Small-Cell Lymphomas
- Lymphoplasmacytoid Lymphoma, CLL
- CLL Lymphoplasmacytoid Lymphoma
- CLL Lymphoplasmacytoid Lymphomas
- Lymphoma, CLL Lymphoplasmacytoid
- Lymphomas, CLL Lymphoplasmacytoid
- Lymphoplasmacytoid Lymphomas, CLL
- Small-Cell Lymphoma
- Small Cell Lymphoma
- B-Cell Chronic Lymphocytic Leukemia
- B Cell Chronic Lymphocytic Leukemia
- B-Cell Leukemia, Chronic
- B Cell Leukemia, Chronic
- B-Cell Leukemias, Chronic
- Chronic B-Cell Leukemia
- Chronic B-Cell Leukemias
- Leukemia, Chronic B-Cell
- Leukemias, Chronic B-Cell
- B-Lymphocytic Leukemia, Chronic
- B Lymphocytic Leukemia, Chronic
- B-Lymphocytic Leukemias, Chronic
- Chronic B-Lymphocytic Leukemia
- Chronic B-Lymphocytic Leukemias
- Leukemia, Chronic B-Lymphocytic
- Leukemias, Chronic B-Lymphocytic
- Lymphoma, Lymphocytic, Well-Differentiated
- Lymphoma, Lymphoplasmacytoid, CLL
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Below are MeSH descriptors whose meaning is more general than "Leukemia, Lymphocytic, Chronic, B-Cell".
- Diseases [C]
- Neoplasms [C04]
- Neoplasms by Histologic Type [C04.557]
- Leukemia [C04.557.337]
- Leukemia, Lymphoid [C04.557.337.428]
- Leukemia, B-Cell [C04.557.337.428.080]
- Leukemia, Lymphocytic, Chronic, B-Cell [C04.557.337.428.080.125]
- Hemic and Lymphatic Diseases [C15]
- Lymphatic Diseases [C15.604]
- Lymphoproliferative Disorders [C15.604.515]
- Leukemia, Lymphoid [C15.604.515.560]
- Leukemia, B-Cell [C15.604.515.560.080]
- Leukemia, Lymphocytic, Chronic, B-Cell [C15.604.515.560.080.125]
- Immune System Diseases [C20]
- Immunoproliferative Disorders [C20.683]
- Lymphoproliferative Disorders [C20.683.515]
- Leukemia, Lymphoid [C20.683.515.528]
- Leukemia, B-Cell [C20.683.515.528.080]
- Leukemia, Lymphocytic, Chronic, B-Cell [C20.683.515.528.080.125]
Below are MeSH descriptors whose meaning is more specific than "Leukemia, Lymphocytic, Chronic, B-Cell".
This graph shows the total number of publications written about "Leukemia, Lymphocytic, Chronic, B-Cell" by people in this website by year, and whether "Leukemia, Lymphocytic, Chronic, B-Cell" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 3 | 0 | 3 | | 1992 | 1 | 0 | 1 | | 1993 | 0 | 1 | 1 | | 1994 | 1 | 1 | 2 | | 1995 | 1 | 1 | 2 | | 1997 | 1 | 1 | 2 | | 1998 | 2 | 2 | 4 | | 1999 | 1 | 2 | 3 | | 2000 | 5 | 0 | 5 | | 2001 | 3 | 0 | 3 | | 2002 | 2 | 0 | 2 | | 2003 | 3 | 0 | 3 | | 2004 | 2 | 0 | 2 | | 2005 | 6 | 0 | 6 | | 2006 | 0 | 1 | 1 | | 2007 | 6 | 1 | 7 | | 2008 | 3 | 0 | 3 | | 2009 | 4 | 0 | 4 | | 2010 | 2 | 3 | 5 | | 2011 | 2 | 0 | 2 | | 2012 | 8 | 0 | 8 | | 2013 | 3 | 0 | 3 | | 2014 | 4 | 0 | 4 | | 2015 | 5 | 0 | 5 | | 2016 | 3 | 1 | 4 | | 2017 | 3 | 1 | 4 | | 2018 | 5 | 0 | 5 | | 2019 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Leukemia, Lymphocytic, Chronic, B-Cell" by people in Profiles.
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Lerner AM, Bennett JE, Pittaluga S, Khil PP, Youn JH, Fahle GA, Frank KM, Dekker JP, Jerussi TD, Sun C, Wiestner A, Gea-Banacloche J. Protracted course of disseminated adenovirus disease with necrotizing granulomas in the liver. Diagn Microbiol Infect Dis. 2019 Jun; 94(2):180-182.
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Woyach JA, Ruppert AS, Heerema NA, Zhao W, Booth AM, Ding W, Bartlett NL, Brander DM, Barr PM, Rogers KA, Parikh SA, Coutre S, Hurria A, Brown JR, Lozanski G, Blachly JS, Ozer HG, Major-Elechi B, Fruth B, Nattam S, Larson RA, Erba H, Litzow M, Owen C, Kuzma C, Abramson JS, Little RF, Smith SE, Stone RM, Mandrekar SJ, Byrd JC. Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL. N Engl J Med. 2018 12 27; 379(26):2517-2528.
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Manso BA, Zhang H, Mikkelson MG, Gwin KA, Secreto CR, Ding W, Parikh SA, Kay NE, Medina KL. Bone marrow hematopoietic dysfunction in untreated chronic lymphocytic leukemia patients. Leukemia. 2019 03; 33(3):638-652.
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Aue G, Sun C, Liu D, Park JH, Pittaluga S, Tian X, Lee E, Soto S, Valdez J, Maric I, Stetler-Stevenson M, Yuan C, Nakamura Y, Muranski P, Wiestner A. Activation of Th1 Immunity within the Tumor Microenvironment Is Associated with Clinical Response to Lenalidomide in Chronic Lymphocytic Leukemia. J Immunol. 2018 10 01; 201(7):1967-1974.
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Byrd JC, Ruppert AS, Heerema NA, Halvorson AE, Hoke E, Smith MR, Godwin JE, Couban S, Fehniger TA, Thirman MJ, Tallman MS, Appelbaum FR, Stone RM, Robinson S, Chang JE, Mandrekar SJ, Larson RA. Lenalidomide consolidation benefits patients with CLL receiving chemoimmunotherapy: results for CALGB 10404 (Alliance). Blood Adv. 2018 07 24; 2(14):1705-1718.
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Baron BW, Thirman MJ, Giurcanu MC, Baron JM. Quercetin Therapy for Selected Patients with PIM1 Kinase-Positive Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Pilot Study. Acta Haematol. 2018; 139(2):132-139.
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Mato A, Nabhan C, Kay NE, Lamanna N, Kipps TJ, Grinblatt DL, Flowers CR, Farber CM, Davids MS, Kiselev P, Swern AS, Bhushan S, Sullivan K, Flick ED, Sharman JP. Prognostic Testing Patterns and Outcomes of Chronic Lymphocytic Leukemia Patients Stratified by Fluorescence In Situ Hybridization/Cytogenetics: A Real-world Clinical Experience in the Connect CLL Registry. Clin Lymphoma Myeloma Leuk. 2018 02; 18(2):114-124.e2.
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Hsu J, Artz A, Mayer SA, Guarner D, Bishop MR, Reich-Slotky R, Smith SM, Greenberg J, Kline J, Ferrante R, Phillips AA, Gergis U, Liu H, Stock W, Cushing M, Shore TB, van Besien K. Combined Haploidentical and Umbilical Cord Blood Allogeneic Stem Cell Transplantation for High-Risk Lymphoma and Chronic Lymphoblastic Leukemia. Biol Blood Marrow Transplant. 2018 02; 24(2):359-365.
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Paley GL, Farooq AV, Lubniewski AJ. Conjunctival Lesion in a Patient With Ocular Graft-vs-Host Disease. JAMA Ophthalmol. 2017 08 01; 135(8):883-884.
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Nabhan C, Mato A, Flowers CR, Grinblatt DL, Lamanna N, Weiss MA, Davids MS, Swern AS, Bhushan S, Sullivan K, Flick ED, Kiselev P, Sharman JP. Characterizing and prognosticating chronic lymphocytic leukemia in the elderly: prospective evaluation on 455 patients treated in the United States. BMC Cancer. 2017 03 16; 17(1):198.
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