 Leukemia, Lymphocytic, Chronic, B-Cell
"Leukemia, Lymphocytic, Chronic, B-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.
| Descriptor ID |
D015451
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| MeSH Number(s) |
C04.557.337.428.080.125 C15.604.515.560.080.125 C20.683.515.528.080.125
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| Concept/Terms |
Leukemia, Lymphocytic, Chronic, B-Cell- Leukemia, Lymphocytic, Chronic, B-Cell
- Lymphocytic Lymphoma, Diffuse, Well-Differentiated
- Lymphocytic Lymphoma, Well Differentiated
- Lymphocytic Lymphoma, Well-Differentiated
- Lymphocytic Lymphomas, Well-Differentiated
- Lymphoma, Well-Differentiated Lymphocytic
- Lymphomas, Well-Differentiated Lymphocytic
- Well-Differentiated Lymphocytic Lymphoma
- Well-Differentiated Lymphocytic Lymphomas
- Lymphoma, Lymphocytic
- Lymphoma, Lymphocytic, Diffuse, Well Differentiated
- Lymphoma, Lymphocytic, Diffuse, Well-Differentiated
- Lymphoma, Lymphocytic, Well Differentiated
- Chronic Lymphocytic Leukemia
- Chronic Lymphocytic Leukemias
- Leukemia, Chronic Lymphocytic
- Leukemias, Chronic Lymphocytic
- Lymphocytic Leukemias, Chronic
- Diffuse Well-Differentiated Lymphocytic Lymphoma
- Diffuse Well Differentiated Lymphocytic Lymphoma
- Leukemia, B Cell, Chronic
- Leukemia, B-Cell, Chronic
- Leukemia, Lymphoblastic, Chronic
- Leukemia, Lymphocytic, Chronic
- Leukemia, Lymphocytic, Chronic, B Cell
- Lymphoblastic Leukemia, Chronic
- Chronic Lymphoblastic Leukemia
- Chronic Lymphoblastic Leukemias
- Leukemia, Chronic Lymphoblastic
- Leukemias, Chronic Lymphoblastic
- Lymphoblastic Leukemias, Chronic
- Lymphocytic Leukemia, Chronic
- Lymphocytic Leukemia, Chronic, B Cell
- Lymphocytic Leukemia, Chronic, B-Cell
- Lymphocytic Lymphoma
- Lymphocytic Lymphomas
- Lymphomas, Lymphocytic
- Lymphocytic Lymphoma, Diffuse, Well Differentiated
- Lymphoma, Small Lymphocytic
- Lymphocytic Lymphoma, Small
- Lymphocytic Lymphomas, Small
- Lymphomas, Small Lymphocytic
- Small Lymphocytic Lymphoma
- Small Lymphocytic Lymphomas
- Lymphoma, Small Lymphocytic, Plasmacytoid
- Lymphoma, Small-Cell
- Lymphoma, Small Cell
- Lymphomas, Small-Cell
- Small-Cell Lymphomas
- Lymphoplasmacytoid Lymphoma, CLL
- CLL Lymphoplasmacytoid Lymphoma
- CLL Lymphoplasmacytoid Lymphomas
- Lymphoma, CLL Lymphoplasmacytoid
- Lymphomas, CLL Lymphoplasmacytoid
- Lymphoplasmacytoid Lymphomas, CLL
- Small-Cell Lymphoma
- Small Cell Lymphoma
- B-Cell Chronic Lymphocytic Leukemia
- B Cell Chronic Lymphocytic Leukemia
- B-Cell Leukemia, Chronic
- B Cell Leukemia, Chronic
- B-Cell Leukemias, Chronic
- Chronic B-Cell Leukemia
- Chronic B-Cell Leukemias
- Leukemia, Chronic B-Cell
- Leukemias, Chronic B-Cell
- B-Lymphocytic Leukemia, Chronic
- B Lymphocytic Leukemia, Chronic
- B-Lymphocytic Leukemias, Chronic
- Chronic B-Lymphocytic Leukemia
- Chronic B-Lymphocytic Leukemias
- Leukemia, Chronic B-Lymphocytic
- Leukemias, Chronic B-Lymphocytic
- Lymphoma, Lymphocytic, Well-Differentiated
- Lymphoma, Lymphoplasmacytoid, CLL
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Below are MeSH descriptors whose meaning is more general than "Leukemia, Lymphocytic, Chronic, B-Cell".
- Diseases [C]
- Neoplasms [C04]
- Neoplasms by Histologic Type [C04.557]
- Leukemia [C04.557.337]
- Leukemia, Lymphoid [C04.557.337.428]
- Leukemia, B-Cell [C04.557.337.428.080]
- Leukemia, Lymphocytic, Chronic, B-Cell [C04.557.337.428.080.125]
- Hemic and Lymphatic Diseases [C15]
- Lymphatic Diseases [C15.604]
- Lymphoproliferative Disorders [C15.604.515]
- Leukemia, Lymphoid [C15.604.515.560]
- Leukemia, B-Cell [C15.604.515.560.080]
- Leukemia, Lymphocytic, Chronic, B-Cell [C15.604.515.560.080.125]
- Immune System Diseases [C20]
- Immunoproliferative Disorders [C20.683]
- Lymphoproliferative Disorders [C20.683.515]
- Leukemia, Lymphoid [C20.683.515.528]
- Leukemia, B-Cell [C20.683.515.528.080]
- Leukemia, Lymphocytic, Chronic, B-Cell [C20.683.515.528.080.125]
Below are MeSH descriptors whose meaning is more specific than "Leukemia, Lymphocytic, Chronic, B-Cell".
This graph shows the total number of publications written about "Leukemia, Lymphocytic, Chronic, B-Cell" by people in this website by year, and whether "Leukemia, Lymphocytic, Chronic, B-Cell" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 3 | 0 | 3 | | 1992 | 1 | 0 | 1 | | 1993 | 0 | 1 | 1 | | 1994 | 1 | 1 | 2 | | 1995 | 1 | 1 | 2 | | 1997 | 1 | 1 | 2 | | 1998 | 2 | 2 | 4 | | 1999 | 1 | 2 | 3 | | 2000 | 5 | 0 | 5 | | 2001 | 3 | 0 | 3 | | 2002 | 2 | 0 | 2 | | 2003 | 3 | 0 | 3 | | 2004 | 2 | 0 | 2 | | 2005 | 6 | 0 | 6 | | 2006 | 0 | 1 | 1 | | 2007 | 6 | 1 | 7 | | 2008 | 3 | 0 | 3 | | 2009 | 4 | 0 | 4 | | 2010 | 2 | 3 | 5 | | 2011 | 2 | 0 | 2 | | 2012 | 8 | 0 | 8 | | 2013 | 3 | 0 | 3 | | 2014 | 4 | 0 | 4 | | 2015 | 5 | 0 | 5 | | 2016 | 3 | 1 | 4 | | 2017 | 3 | 1 | 4 | | 2018 | 6 | 0 | 6 | | 2019 | 1 | 1 | 2 | | 2020 | 3 | 1 | 4 | | 2021 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Leukemia, Lymphocytic, Chronic, B-Cell" by people in Profiles.
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Lu P, Wang S, Franzen CA, Venkataraman G, McClure R, Li L, Wu W, Niu N, Sukhanova M, Pei J, Baldwin DA, Nejati R, Wasik MA, Khan N, Tu Y, Gao J, Chen Y, Ma S, Larson RA, Wang YL. Ibrutinib and venetoclax target distinct subpopulations of CLL cells: implication for residual disease eradication. Blood Cancer J. 2021 02 18; 11(2):39.
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Stilgenbauer S, Morschhauser F, Wendtner CM, Cartron G, Hallek M, Eichhorst B, Kozloff MF, Giever T, Lozanski G, Jiang Y, Huang H, Pignataro DS, Schary W, Humphrey K, Mobasher M, Salles G. Venetoclax plus bendamustine-rituximab or bendamustine-obinutuzumab in chronic lymphocytic leukemia: final results of a phase 1b study (GO28440). Haematologica. 2020 10 29; Online ahead of print.
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Mato A, Nabhan C, Lamanna N, Kay NE, Grinblatt DL, Flowers CR, Farber CM, Davids MS, Swern AS, Sullivan K, Flick ED, Gressett Ussery SM, Gharibo M, Kiselev P, Sharman JP. The Connect CLL Registry: final analysis of 1494 patients with chronic lymphocytic leukemia across 199 US sites. Blood Adv. 2020 04 14; 4(7):1407-1418.
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Tian S, Xiong Y, Liu H, Niu L, Guo J, Liao M, Xiao SY. Pathological study of the 2019 novel coronavirus disease (COVID-19) through postmortem core biopsies. Mod Pathol. 2020 06; 33(6):1007-1014.
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Agius R, Brieghel C, Andersen MA, Pearson AT, Ledergerber B, Cozzi-Lepri A, Louzoun Y, Andersen CL, Bergstedt J, von Stemann JH, Jørgensen M, Tang ME, Fontes M, Bahlo J, Herling CD, Hallek M, Lundgren J, MacPherson CR, Larsen J, Niemann CU. Machine learning can identify newly diagnosed patients with CLL at high risk of infection. Nat Commun. 2020 01 17; 11(1):363.
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Awan FT, Thirman MJ, Patel-Donnelly D, Assouline S, Rao AV, Ye W, Hill B, Sharman JP. Entospletinib monotherapy in patients with relapsed or refractory chronic lymphocytic leukemia previously treated with B-cell receptor inhibitors: results of a phase 2 study. Leuk Lymphoma. 2019 08; 60(8):1972-1977.
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Lerner AM, Bennett JE, Pittaluga S, Khil PP, Youn JH, Fahle GA, Frank KM, Dekker JP, Jerussi TD, Sun C, Wiestner A, Gea-Banacloche J. Protracted course of disseminated adenovirus disease with necrotizing granulomas in the liver. Diagn Microbiol Infect Dis. 2019 Jun; 94(2):180-182.
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Woyach JA, Ruppert AS, Heerema NA, Zhao W, Booth AM, Ding W, Bartlett NL, Brander DM, Barr PM, Rogers KA, Parikh SA, Coutre S, Hurria A, Brown JR, Lozanski G, Blachly JS, Ozer HG, Major-Elechi B, Fruth B, Nattam S, Larson RA, Erba H, Litzow M, Owen C, Kuzma C, Abramson JS, Little RF, Smith SE, Stone RM, Mandrekar SJ, Byrd JC. Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL. N Engl J Med. 2018 12 27; 379(26):2517-2528.
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Manso BA, Zhang H, Mikkelson MG, Gwin KA, Secreto CR, Ding W, Parikh SA, Kay NE, Medina KL. Bone marrow hematopoietic dysfunction in untreated chronic lymphocytic leukemia patients. Leukemia. 2019 03; 33(3):638-652.
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Aue G, Sun C, Liu D, Park JH, Pittaluga S, Tian X, Lee E, Soto S, Valdez J, Maric I, Stetler-Stevenson M, Yuan C, Nakamura Y, Muranski P, Wiestner A. Activation of Th1 Immunity within the Tumor Microenvironment Is Associated with Clinical Response to Lenalidomide in Chronic Lymphocytic Leukemia. J Immunol. 2018 10 01; 201(7):1967-1974.
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