"Lipase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. It is produced by glands on the tongue and by the pancreas and initiates the digestion of dietary fats. (From Dorland, 27th ed) EC 3.1.1.3.
| Descriptor ID |
D008049
|
| MeSH Number(s) |
D08.811.277.352.100.400
|
| Concept/Terms |
Lipase- Lipase
- Triacylglycerol Lipase
- Triolean Hydrolase
- Hydrolase, Triolean
- Triglyceridase
- Triglyceride Lipase
- Lipase, Triglyceride
- Triacylglycerol Hydrolase
- Hydrolase, Triacylglycerol
- Tributyrinase
|
Below are MeSH descriptors whose meaning is more general than "Lipase".
Below are MeSH descriptors whose meaning is more specific than "Lipase".
This graph shows the total number of publications written about "Lipase" by people in this website by year, and whether "Lipase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 2 | 3 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 2 | 2 |
| 2021 | 1 | 1 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lipase" by people in Profiles.
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Machine learning to predict pediatric choledocholithiasis: A Western Pediatric Surgery Research Consortium retrospective study. Surgery. 2023 10; 174(4):934-939.
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Structural and functional insights into ABHD5, a ligand-regulated lipase co-activator. Sci Rep. 2022 02 16; 12(1):2565.
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Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial. Sci Transl Med. 2021 04 21; 13(590).
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Loss of ephrin B2 receptor (EPHB2) sets lipid rheostat by regulating proteins DGAT1 and ATGL inducing lipid droplet storage in prostate cancer cells. Lab Invest. 2021 07; 101(7):921-934.
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Phenome-wide association studies across large population cohorts support drug target validation. Nat Commun. 2018 10 16; 9(1):4285.
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PEDF regulates plasticity of a novel lipid-MTOC axis in prostate cancer-associated fibroblasts. J Cell Sci. 2018 07 11; 131(13).
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Monobody-Mediated Alteration of Lipase Substrate Specificity. ACS Chem Biol. 2018 06 15; 13(6):1487-1492.
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Molecular Basis of ABHD5 Lipolysis Activation. Sci Rep. 2017 02 17; 7:42589.
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The gastrin-releasing peptide analog bombesin preserves exocrine and endocrine pancreas morphology and function during parenteral nutrition. Am J Physiol Gastrointest Liver Physiol. 2015 Sep 15; 309(6):G431-42.
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Atenolol induced HDL-C change in the pharmacogenomic evaluation of antihypertensive responses (PEAR) study. PLoS One. 2013; 8(10):e76984.