"Carboxylesterase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Carboxylesterase is a serine-dependent esterase with wide substrate specificity. The enzyme is involved in the detoxification of XENOBIOTICS and the activation of ester and of amide PRODRUGS.
| Descriptor ID |
D043182
|
| MeSH Number(s) |
D08.811.277.352.100.100
|
| Concept/Terms |
Carboxylesterase- Carboxylesterase
- Isocarboxazid amidase
- amidase, Isocarboxazid
- Non-specific Esterase
- Esterase, Non-specific
- Non specific Esterase
- Nonspecific Esterase
- Esterase, Nonspecific
- Procaine Esterase
- Esterase, Procaine
- Ali-esterase
- Ali esterase
- B-esterase
- B esterase
- CAP-hydrolyzing Enzyme
- CAP hydrolyzing Enzyme
- Enzyme, CAP-hydrolyzing
- Capsaicin-Hydrolyzing Enzyme
- Capsaicin Hydrolyzing Enzyme
- Enzyme, Capsaicin-Hydrolyzing
- Carboxyesterase
- Carboxylate Esterase
- Esterase, Carboxylate
- Carboxylester Lipase
- Lipase, Carboxylester
- Carboxylesterase B
- Carboxylic Ester Hydrolase
- Ester Hydrolase, Carboxylic
- Hydrolase, Carboxylic Ester
- Naproxen Esterase
- Esterase, Naproxen
- Non-specific Carboxylesterase
- Carboxylesterase, Non-specific
- Non specific Carboxylesterase
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Below are MeSH descriptors whose meaning is more general than "Carboxylesterase".
Below are MeSH descriptors whose meaning is more specific than "Carboxylesterase".
This graph shows the total number of publications written about "Carboxylesterase" by people in this website by year, and whether "Carboxylesterase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Carboxylesterase" by people in Profiles.
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Determination and analysis of single nucleotide polymorphisms and haplotype structure of the human carboxylesterase 2 gene. Pharmacogenetics. 2004 Sep; 14(9):595-605.
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Characterization of multiple promoters in the human carboxylesterase 2 gene. Pharmacogenetics. 2003 Jul; 13(7):425-35.
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Characterization of a VNTR polymorphism in the coding region of the CEL gene. J Hum Genet. 2002; 47(4):213-5.
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Characterization of CPT-11 hydrolysis by human liver carboxylesterase isoforms hCE-1 and hCE-2. Cancer Res. 2000 Mar 01; 60(5):1189-92.
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Divergent and conserved features in the spatial expression of the Drosophila pseudoobscura esterase-5B gene and the esterase-6 gene of Drosophila melanogaster. Proc Natl Acad Sci U S A. 1997 Jul 22; 94(15):7735-41.
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Localization of sequences controlling the spatial, temporal, and sex-specific expression of the esterase 6 locus in Drosophila melanogaster adults. Proc Natl Acad Sci U S A. 1993 Jul 01; 90(13):6233-7.
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Cloning of the esterase D gene: a polymorphic gene probe closely linked to the retinoblastoma locus on chromosome 13. Proc Natl Acad Sci U S A. 1986 Sep; 83(17):6573-7.
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The cloning and expression of the gene encoding organ-specific esterase S from the genome of Drosophila virilis. EMBO J. 1983; 2(1):1-7.