 Neurotransmitter Uptake Inhibitors
"Neurotransmitter Uptake Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects.
| Descriptor ID |
D014179
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| MeSH Number(s) |
D27.505.519.625.600 D27.505.696.577.600
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| Concept/Terms |
Neurotransmitter Uptake Inhibitors- Neurotransmitter Uptake Inhibitors
- Uptake Inhibitors, Neurotransmitter
- Reuptake Inhibitors, Neurotransmitter
- Inhibitors, Neurotransmitter Reuptake
- Neurotransmitter Reuptake Inhibitors
- Transmitter Uptake Inhibitors, Neuronal
- Inhibitors, Neurotransmitter Uptake
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Below are MeSH descriptors whose meaning is more general than "Neurotransmitter Uptake Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Neurotransmitter Uptake Inhibitors".
This graph shows the total number of publications written about "Neurotransmitter Uptake Inhibitors" by people in this website by year, and whether "Neurotransmitter Uptake Inhibitors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2001 | 0 | 2 | 2 |
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Below are the most recent publications written about "Neurotransmitter Uptake Inhibitors" by people in Profiles.
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Lovinger DM. Presynaptic modulation by endocannabinoids. Handb Exp Pharmacol. 2008; (184):435-77.
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Savas A, Warnke PC, Ginap T, Feuerstein TJ, Ostertag CB. The effects of continuous and single-dose radiation on choline uptake in organotypic tissue slice cultures of rabbit hippocampus. Neurol Res. 2001 Sep; 23(6):669-75.
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Kim JH, Perugini M, Austin JD, Vezina P. Previous exposure to amphetamine enhances the subsequent locomotor response to a D1 dopamine receptor agonist when glutamate reuptake is inhibited. J Neurosci. 2001 Mar 01; 21(5):RC133.
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Kim JH, Vezina P. Blockade of glutamate reuptake in the rat nucleus accumbens increases locomotor activity. Brain Res. 1999 Feb 20; 819(1-2):165-9.
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Covert RF, Schreiber MD, Tebbett IR, Torgerson LJ. Hemodynamic and cerebral blood flow effects of cocaine, cocaethylene and benzoylecgonine in conscious and anesthetized fetal lambs. J Pharmacol Exp Ther. 1994 Jul; 270(1):118-26.
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