"Rats, Sprague-Dawley" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A strain of albino rat used widely for experimental purposes because of its calmness and ease of handling. It was developed by the Sprague-Dawley Animal Company.
| Descriptor ID |
D017207
|
| MeSH Number(s) |
B01.050.150.900.649.313.992.635.505.700.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Rats, Sprague-Dawley".
Below are MeSH descriptors whose meaning is more specific than "Rats, Sprague-Dawley".
This graph shows the total number of publications written about "Rats, Sprague-Dawley" by people in this website by year, and whether "Rats, Sprague-Dawley" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 32 | 32 |
| 1997 | 1 | 45 | 46 |
| 1998 | 1 | 44 | 45 |
| 1999 | 0 | 37 | 37 |
| 2000 | 0 | 31 | 31 |
| 2001 | 0 | 40 | 40 |
| 2002 | 0 | 33 | 33 |
| 2003 | 0 | 40 | 40 |
| 2004 | 0 | 34 | 34 |
| 2005 | 0 | 44 | 44 |
| 2006 | 0 | 38 | 38 |
| 2007 | 0 | 45 | 45 |
| 2008 | 0 | 38 | 38 |
| 2009 | 0 | 44 | 44 |
| 2010 | 0 | 39 | 39 |
| 2011 | 0 | 36 | 36 |
| 2012 | 0 | 34 | 34 |
| 2013 | 0 | 22 | 22 |
| 2014 | 0 | 35 | 35 |
| 2015 | 0 | 18 | 18 |
| 2016 | 0 | 28 | 28 |
| 2017 | 0 | 23 | 23 |
| 2018 | 0 | 21 | 21 |
| 2019 | 0 | 21 | 21 |
| 2020 | 0 | 15 | 15 |
| 2021 | 0 | 18 | 18 |
| 2022 | 0 | 5 | 5 |
| 2023 | 0 | 5 | 5 |
| 2024 | 2 | 9 | 11 |
| 2025 | 0 | 7 | 7 |
| 2026 | 0 | 7 | 7 |
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Below are the most recent publications written about "Rats, Sprague-Dawley" by people in Profiles.
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Amphetamine produces enhanced behavioral responding in sensitized male rats: Parallel changes in AMPA receptor surface expression and PKC signaling in the NAcc. Prog Neuropsychopharmacol Biol Psychiatry. 2026 Aug 30; 149:111837.
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Luteolin decreases sFlt-1 and mean arterial pressure in the RUPP animal model of placental ischemia. Placenta. 2026 Aug; 182:150-157.
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Genetic Architecture of Addiction-Relevant Behaviors in Outbred Sprague-Dawley Rats Reveals Loci for Anxiety-Like and Nociceptive Traits. Genes Brain Behav. 2026 Jun; 25(3):e70053.
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Controlled release of rhBMP-2 from nanoparticle-loaded biomimetic graft promotes bone regeneration in a rat spinal fusion model. Biomater Adv. 2026 Nov; 188:214989.
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Dynamin 2 Regulates Mitochondrial Mitotic Fission in Pulmonary Hypertension. Circ Res. 2026 May 22; 138(11):e327028.
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Injectable hydrogel-based localized delivery of IDO-galectin-3 mitigates neuroinflammation and promotes neuronal sparing after spinal cord contusion in rats. J Mater Chem B. 2026 Mar 18; 14(11):3464-3479.
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A single intra-articular injection of IDO-Gal3 shifts synovial fluid metabolic profiles for up to six weeks in male rats with knee instability. Biochimie. 2026 Sep; 248:107-120.
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Intracellular calcium release activates carotid body afferents by fentanyl. Function (Oxf). 2026 02 01; 7(1):e0782025.
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Studies in rats of a target specific and reversible general anesthetic with a favorable safety profile. PLoS One. 2025; 20(11):e0335589.
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Activation of the Carotid Body by Kappa Opioid Receptors Mitigates Fentanyl-Induced Respiratory Depression. Function (Oxf). 2025 05 19; 6(3).