Macrophage Colony-Stimulating Factor
"Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).
| Descriptor ID |
D016173
|
| MeSH Number(s) |
D12.644.276.374.410.240.500 D12.776.395.240.500 D12.776.467.374.410.240.500 D23.529.374.410.240.500
|
| Concept/Terms |
Macrophage Colony-Stimulating Factor- Macrophage Colony-Stimulating Factor
- M-CSF
- CSF-1
- CSF-M
- Colony-Stimulating Factor 1
- Colony Stimulating Factor 1
- Colony-Stimulating Factor, Macrophage
- Colony Stimulating Factor, Macrophage
|
Below are MeSH descriptors whose meaning is more general than "Macrophage Colony-Stimulating Factor".
Below are MeSH descriptors whose meaning is more specific than "Macrophage Colony-Stimulating Factor".
This graph shows the total number of publications written about "Macrophage Colony-Stimulating Factor" by people in this website by year, and whether "Macrophage Colony-Stimulating Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 2000 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Macrophage Colony-Stimulating Factor" by people in Profiles.
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A spatially restricted fibrotic niche in pulmonary fibrosis is sustained by M-CSF/M-CSFR signalling in monocyte-derived alveolar macrophages. Eur Respir J. 2020 01; 55(1).
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Deficits in Enrichment-Dependent Neurogenesis and Enhanced Anxiety Behaviors Mediated by Expression of Alzheimer's Disease-Linked Ps1 Variants Are Rescued by Microglial Depletion. J Neurosci. 2019 08 21; 39(34):6766-6780.
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Genetic and pharmacological targeting of CSF-1/CSF-1R inhibits tumor-associated macrophages and impairs BRAF-induced thyroid cancer progression. PLoS One. 2013; 8(1):e54302.
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In vitro derivation of macrophage from guinea pig bone marrow with human M-CSF. J Immunol Methods. 2013 Mar 29; 389(1-2):88-94.
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Donor and recipient cell surface colony stimulating factor-1 promote neointimal formation in transplant-associated arteriosclerosis. Arterioscler Thromb Vasc Biol. 2013 Jan; 33(1):87-95.
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Macrophages require Skap2 and Sirpa for integrin-stimulated cytoskeletal rearrangement. J Cell Sci. 2012 Nov 15; 125(Pt 22):5535-45.
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Phase II study of dasatinib in patients with previously treated malignant mesothelioma (cancer and leukemia group B 30601): a brief report. J Thorac Oncol. 2012 Apr; 7(4):755-9.
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Coordinate regulation of tissue macrophage and dendritic cell population dynamics by CSF-1. J Exp Med. 2011 Aug 29; 208(9):1901-16.
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PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2. Nat Med. 2010 May; 16(5):580-5, 1p following 585.
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Colony-stimulating factor-1 increases osteoclast intracellular pH and promotes survival via the electroneutral Na/HCO3 cotransporter NBCn1. Endocrinology. 2007 Feb; 148(2):831-40.