"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Descriptor ID |
D000544
|
| MeSH Number(s) |
C10.228.140.380.100 C10.574.945.249 F03.615.400.100
|
| Concept/Terms |
Alzheimer Disease- Alzheimer Disease
- Alzheimer's Disease
- Dementia, Senile
- Senile Dementia
- Dementia, Alzheimer Type
- Alzheimer Type Dementia
- Alzheimer-Type Dementia (ATD)
- Alzheimer Type Dementia (ATD)
- Dementia, Alzheimer-Type (ATD)
- Alzheimer Type Senile Dementia
- Primary Senile Degenerative Dementia
- Dementia, Primary Senile Degenerative
- Alzheimer Sclerosis
- Sclerosis, Alzheimer
- Alzheimer Syndrome
- Alzheimer Dementia
- Alzheimer Dementias
- Dementia, Alzheimer
- Dementias, Alzheimer
- Senile Dementia, Alzheimer Type
Familial Alzheimer Disease (FAD)- Familial Alzheimer Disease (FAD)
- Alzheimer Disease, Familial (FAD)
- Alzheimer Diseases, Familial (FAD)
- Familial Alzheimer Diseases (FAD)
|
Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".
Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".
This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 13 | 1 | 14 |
| 1997 | 10 | 3 | 13 |
| 1998 | 8 | 8 | 16 |
| 1999 | 9 | 2 | 11 |
| 2000 | 6 | 5 | 11 |
| 2001 | 4 | 4 | 8 |
| 2002 | 9 | 3 | 12 |
| 2003 | 11 | 4 | 15 |
| 2004 | 15 | 0 | 15 |
| 2005 | 12 | 6 | 18 |
| 2006 | 12 | 3 | 15 |
| 2007 | 10 | 2 | 12 |
| 2008 | 8 | 8 | 16 |
| 2009 | 5 | 2 | 7 |
| 2010 | 10 | 6 | 16 |
| 2011 | 8 | 8 | 16 |
| 2012 | 8 | 1 | 9 |
| 2013 | 14 | 2 | 16 |
| 2014 | 7 | 1 | 8 |
| 2015 | 7 | 3 | 10 |
| 2016 | 11 | 4 | 15 |
| 2017 | 16 | 1 | 17 |
| 2018 | 18 | 4 | 22 |
| 2019 | 18 | 2 | 20 |
| 2020 | 12 | 2 | 14 |
| 2021 | 18 | 4 | 22 |
| 2022 | 22 | 0 | 22 |
| 2023 | 47 | 0 | 47 |
| 2024 | 34 | 4 | 38 |
| 2025 | 18 | 0 | 18 |
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Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.
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PICALM Alzheimer's risk allele causes aberrant lipid droplets in microglia. Nature. 2025 Oct; 646(8087):1178-1186.
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Is US residence a risk factor for Alzheimer's disease? J Alzheimers Dis. 2025 Sep; 107(2):496-498.
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Hyperphosphorylated Tau Induces Cortical Hypoexcitability in Transgenic Mouse Models: A Meta-Analysis. J Integr Neurosci. 2025 Aug 28; 24(8):39192.
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Identifying patients with mild cognitive impairment at high risk of transitioning to Alzheimer's disease using routinely collected data. J Alzheimers Dis. 2025 Nov; 108(1_suppl):S334-S343.
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Association of Alzheimer's disease concerns with amyloid burden and lifestyle behaviors in cognitively unimpaired older adults. Alzheimers Dement. 2025 Jun; 21(6):e70225.
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Large-scale plasma proteomic profiling unveils diagnostic biomarkers and pathways for Alzheimer's disease. Nat Aging. 2025 Jun; 5(6):1114-1131.
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The gut microbiome controls reactive astrocytosis during Aß amyloidosis via propionate-mediated regulation of IL-17. J Clin Invest. 2025 Jul 01; 135(13).
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Alzheimer's disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication. Mol Neurodegener. 2025 May 03; 20(1):51.
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Exploring novel therapeutic strategies: Could psychedelic perspectives offer promising solutions for Alzheimer's disease comorbidities? Dialogues Clin Neurosci. 2025 12; 27(1):1-12.
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Amyloid PET in Sporadic Early- Versus Late-Onset Alzheimer's Disease: Comparison of the LEADS and ADNI Cohorts. Ann Neurol. 2025 Aug; 98(2):236-248.