"Clavulanic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Clavulanic acid and its salts and esters. The acid is a suicide inhibitor of bacterial beta-lactamase enzymes from Streptomyces clavuligerus. Administered alone, it has only weak antibacterial activity against most organisms, but given in combination with other beta-lactam antibiotics it prevents antibiotic inactivation by microbial lactamase.
| Descriptor ID |
D019818
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| MeSH Number(s) |
D02.065.589.099.374.160 D03.633.100.300.374.160
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| Concept/Terms |
Clavulanate Potassium- Clavulanate Potassium
- Potassium, Clavulanate
- Potassium Clavulanate
- Clavulanate, Potassium
- Clavulanic Acid, Monopotassium Salt
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Below are MeSH descriptors whose meaning is more general than "Clavulanic Acid".
Below are MeSH descriptors whose meaning is more specific than "Clavulanic Acid".
This graph shows the total number of publications written about "Clavulanic Acid" by people in this website by year, and whether "Clavulanic Acid" was a major or minor topic of these publications.
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Below are the most recent publications written about "Clavulanic Acid" by people in Profiles.
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Selection and characterization of beta-lactam-beta-lactamase inactivator-resistant mutants following PCR mutagenesis of the TEM-1 beta-lactamase gene. Antimicrob Agents Chemother. 1998 Jul; 42(7):1542-8.
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Reversal of clavulanate resistance conferred by a Ser-244 mutant of TEM-1 beta-lactamase as a result of a second mutation (Arg to Ser at position 164) that enhances activity against ceftazidime. Antimicrob Agents Chemother. 1994 May; 38(5):1134-9.