"Vinca Alkaloids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.
| Descriptor ID |
D014748
|
| MeSH Number(s) |
D03.132.436.681.827 D03.633.100.473.402.681.827
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Vinca Alkaloids".
Below are MeSH descriptors whose meaning is more specific than "Vinca Alkaloids".
This graph shows the total number of publications written about "Vinca Alkaloids" by people in this website by year, and whether "Vinca Alkaloids" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Vinca Alkaloids" by people in Profiles.
-
Cancer pharmacoethnicity: ethnic differences in susceptibility to the effects of chemotherapy. Clin Cancer Res. 2009 Aug 01; 15(15):4806-14.
-
Determination of vinca alkaloids in human plasma by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry. Cancer Chemother Pharmacol. 1997; 39(4):286-90.
-
The alpha 1-adrenergic photoaffinity probe [125I]arylazidoprazosin binds to a specific peptide of P-glycoprotein in multidrug-resistant cells. Biochem Biophys Res Commun. 1990 Jan 15; 166(1):259-66.