Vitamin D-Binding Protein
"Vitamin D-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alpha-globulin found in the plasma of man and other vertebrates. It is apparently synthesized in the liver and carries vitamin D and its metabolites through the circulation and mediates the response of tissue. It is also known as group-specific component (Gc). Gc subtypes are used to determine specific phenotypes and gene frequencies. These data are employed in the classification of population groups, paternity investigations, and in forensic medicine.
Descriptor ID |
D014809
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MeSH Number(s) |
D12.776.157.920
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Concept/Terms |
Vitamin D-Binding Protein- Vitamin D-Binding Protein
- Vitamin D Binding Protein
- 25-Hydroxycholecalciferol-Binding Protein
- 25 Hydroxycholecalciferol Binding Protein
- 25-Hydroxyvitamin D-Binding Protein
- 25 Hydroxyvitamin D Binding Protein
- Vitamin D-Binding Globulin
- Globulin, Vitamin D-Binding
- Vitamin D Binding Globulin
- Gc Globulin
- Globulin, Gc
- Group-Specific Component Globulin
- Component Globulin, Group-Specific
- Globulin, Group-Specific Component
- Group Specific Component Globulin
- Transcalciferin
- 25-HCC-Binding Protein
- 25 HCC Binding Protein
- Calciferol-Binding Protein
- Calciferol Binding Protein
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Below are MeSH descriptors whose meaning is more general than "Vitamin D-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "Vitamin D-Binding Protein".
This graph shows the total number of publications written about "Vitamin D-Binding Protein" by people in this website by year, and whether "Vitamin D-Binding Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1986 | 0 | 1 | 1 | 1991 | 1 | 0 | 1 | 2006 | 0 | 1 | 1 | 2010 | 1 | 0 | 1 | 2014 | 0 | 1 | 1 | 2015 | 0 | 1 | 1 | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Vitamin D-Binding Protein" by people in Profiles.
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Eckard AR, Thierry-Palmer M, Silvestrov N, Rosebush JC, O'Riordan MA, Daniels JE, Uribe-Leitz M, Labbato D, Ruff JH, Singh RJ, Tangpricha V, McComsey GA. Effects of cholecalciferol supplementation on serum and urinary vitamin D metabolites and binding protein in HIV-infected youth. J Steroid Biochem Mol Biol. 2017 04; 168:38-48.
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Fitzgerald KC, Munger KL, Köchert K, Arnason BG, Comi G, Cook S, Goodin DS, Filippi M, Hartung HP, Jeffery DR, O'Connor P, Suarez G, Sandbrink R, Kappos L, Pohl C, Ascherio A. Association of Vitamin D Levels With Multiple Sclerosis Activity and Progression in Patients Receiving Interferon Beta-1b. JAMA Neurol. 2015 Dec; 72(12):1458-65.
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Liong S, Di Quinzio MK, Fleming G, Permezel M, Rice GE, Georgiou HM. New biomarkers for the prediction of spontaneous preterm labour in symptomatic pregnant women: a comparison with fetal fibronectin. BJOG. 2015 Feb; 122(3):370-9.
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Powe CE, Seely EW, Rana S, Bhan I, Ecker J, Karumanchi SA, Thadhani R. First trimester vitamin D, vitamin D binding protein, and subsequent preeclampsia. Hypertension. 2010 Oct; 56(4):758-63.
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Wang Y, Zhou J, Minto AW, Hack BK, Alexander JJ, Haas M, Li YC, Heilig CW, Quigg RJ. Altered vitamin D metabolism in type II diabetic mouse glomeruli may provide protection from diabetic nephropathy. Kidney Int. 2006 Sep; 70(5):882-91.
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Yu HM, Li XJ, Kadam AL, Cheng CY, Koide SS. Human testis vitamin D binding protein involved in infertility. Arch Androl. 1994 Sep-Oct; 33(2):119-28.
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Teegarden D, Meredith SC, Sitrin MD. Determination of the affinity of vitamin D metabolites to serum vitamin D binding protein using assay employing lipid-coated polystyrene beads. Anal Biochem. 1991 Dec; 199(2):293-9.
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Cooke NE, Willard HF, David EV, George DL. Direct regional assignment of the gene for vitamin D binding protein (Gc-globulin) to human chromosome 4q11-q13 and identification of an associated DNA polymorphism. Hum Genet. 1986 Jul; 73(3):225-9.
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Gusella JA, Gilliam TC, MacDonald ME, Cheng SV, Tanzi RE. Molecular genetics of human chromosome 4. J Med Genet. 1986 Jun; 23(3):193-9.
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