 Lupus Erythematosus, Systemic
"Lupus Erythematosus, Systemic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
| Descriptor ID |
D008180
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| MeSH Number(s) |
C17.300.480 C20.111.590
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lupus Erythematosus, Systemic".
Below are MeSH descriptors whose meaning is more specific than "Lupus Erythematosus, Systemic".
This graph shows the total number of publications written about "Lupus Erythematosus, Systemic" by people in this website by year, and whether "Lupus Erythematosus, Systemic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 | | 1981 | 1 | 2 | 3 | | 1982 | 3 | 0 | 3 | | 1983 | 3 | 0 | 3 | | 1984 | 2 | 2 | 4 | | 1985 | 0 | 1 | 1 | | 1986 | 2 | 0 | 2 | | 1987 | 1 | 0 | 1 | | 1988 | 1 | 1 | 2 | | 1989 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1992 | 1 | 1 | 2 | | 1994 | 1 | 1 | 2 | | 1995 | 0 | 1 | 1 | | 1996 | 1 | 2 | 3 | | 1998 | 1 | 0 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 2 | 0 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 1 | 2 | | 2004 | 4 | 3 | 7 | | 2005 | 7 | 0 | 7 | | 2006 | 3 | 0 | 3 | | 2007 | 6 | 1 | 7 | | 2008 | 7 | 2 | 9 | | 2009 | 9 | 0 | 9 | | 2010 | 12 | 0 | 12 | | 2011 | 9 | 0 | 9 | | 2012 | 13 | 0 | 13 | | 2013 | 8 | 0 | 8 | | 2014 | 3 | 1 | 4 | | 2015 | 6 | 2 | 8 | | 2016 | 2 | 0 | 2 | | 2017 | 4 | 1 | 5 | | 2018 | 4 | 2 | 6 | | 2020 | 1 | 2 | 3 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lupus Erythematosus, Systemic" by people in Profiles.
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Reder AT, Centonze D, Naylor ML, Nagpal A, Rajbhandari R, Altincatal A, Kim M, Berdofe A, Radhakrishnan M, Jung E, Sandrock AW, Smirnakis K, Popescu C, de Moor C. COVID-19 in Patients with Multiple Sclerosis: Associations with Disease-Modifying Therapies. CNS Drugs. 2021 03; 35(3):317-330.
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Chen PM, Wilson PC, Shyer JA, Veselits M, Steach HR, Cui C, Moeckel G, Clark MR, Craft J. Kidney tissue hypoxia dictates T cell-mediated injury in murine lupus nephritis. Sci Transl Med. 2020 04 08; 12(538).
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Kinloch AJ, Cascino MD, Dai J, Bermea RS, Ko K, Vesselits M, Dragone LL, Mor Vaknin N, Legendre M, Markovitz DM, Okoreeh MK, Townsend MJ, Clark MR. Anti-vimentin antibodies: a unique antibody class associated with therapy-resistant lupus nephritis. Lupus. 2020 May; 29(6):569-577.
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Cohen RD, Bhayat F, Blake A, Travis S. The Safety Profile of Vedolizumab in Ulcerative Colitis and Crohn's Disease: 4 Years of Global Post-marketing Data. J Crohns Colitis. 2020 Feb 10; 14(2):192-204.
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Hanscombe KB, Morris DL, Noble JA, Dilthey AT, Tombleson P, Kaufman KM, Comeau M, Langefeld CD, Alarcon-Riquelme ME, Gaffney PM, Jacob CO, Sivils KL, Tsao BP, Alarcon GS, Brown EE, Croker J, Edberg J, Gilkeson G, James JA, Kamen DL, Kelly JA, McCune J, Merrill JT, Petri M, Ramsey-Goldman R, Reveille JD, Salmon JE, Scofield H, Utset T, Wallace DJ, Weisman MH, Kimberly RP, Harley JB, Lewis CM, Criswell LA, Vyse TJ. Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans. Hum Mol Genet. 2018 11 01; 27(21):3813-3824.
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Shipman WD, Chyou S, Ramanathan A, Izmirly PM, Sharma S, Pannellini T, Dasoveanu DC, Qing X, Magro CM, Granstein RD, Lowes MA, Pamer EG, Kaplan DH, Salmon JE, Mehrara BJ, Young JW, Clancy RM, Blobel CP, Lu TT. A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity. Sci Transl Med. 2018 08 15; 10(454).
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Edens C, Rodrigues BC, Lacerda MI, Dos Santos FC, De Jesús GR, De Jesús NR, Levy RA, Leatherwood C, Mandel J, Bermas B. Challenging cases in rheumatic pregnancies. Rheumatology (Oxford). 2018 07 01; 57(suppl_5):v18-v25.
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Bhattacharya J, Pappas K, Toz B, Aranow C, Mackay M, Gregersen PK, Doumbo O, Traore AK, Lesser ML, McMahon M, Utset T, Silverman E, Levy D, McCune WJ, Jolly M, Wallace D, Weisman M, Romero-Diaz J, Diamond B. Serologic features of cohorts with variable genetic risk for systemic lupus erythematosus. Mol Med. 2018 06 01; 24(1):24.
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Tu E, Chia CPZ, Chen W, Zhang D, Park SA, Jin W, Wang D, Alegre ML, Zhang YE, Sun L, Chen W. T Cell Receptor-Regulated TGF-ß Type I Receptor Expression Determines T Cell Quiescence and Activation. Immunity. 2018 04 17; 48(4):745-759.e6.
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Kalinina O, Louzoun Y, Wang Y, Utset T, Weigert M. Origins and specificity of auto-antibodies in Sm+ SLE patients. J Autoimmun. 2018 06; 90:94-104.
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