 Microsomes
"Microsomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Artifactual vesicles formed from the endoplasmic reticulum when cells are disrupted. They are isolated by differential centrifugation and are composed of three structural features: rough vesicles, smooth vesicles, and ribosomes. Numerous enzyme activities are associated with the microsomal fraction. (Glick, Glossary of Biochemistry and Molecular Biology, 1990; from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
| Descriptor ID |
D008861
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| MeSH Number(s) |
A11.284.835.540
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Microsomes".
Below are MeSH descriptors whose meaning is more specific than "Microsomes".
This graph shows the total number of publications written about "Microsomes" by people in this website by year, and whether "Microsomes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 2 | 2 | | 1982 | 0 | 1 | 1 | | 1984 | 0 | 1 | 1 | | 1988 | 2 | 0 | 2 | | 1989 | 0 | 1 | 1 | | 1992 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1994 | 0 | 3 | 3 | | 1995 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Microsomes" by people in Profiles.
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RamÃrez J, Mirkov S, House LK, Ratain MJ. Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10. Drug Metab Dispos. 2015 Jul; 43(7):928-35.
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Lecomte JT, Mukhopadhyay K, Pond MP. Structural and thermodynamic encoding in the sequence of rat microsomal cytochrome b(5). Biopolymers. 2008 May; 89(5):428-42.
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Musch MW, Puffer AB, Goldstein L. Volume expansion stimulates monoubiquitination and endocytosis of surface-expressed skate anion-exchanger isoform. Am J Physiol Regul Integr Comp Physiol. 2008 May; 294(5):R1657-65.
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Sontag TJ, Parker RS. Influence of major structural features of tocopherols and tocotrienols on their omega-oxidation by tocopherol-omega-hydroxylase. J Lipid Res. 2007 May; 48(5):1090-8.
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Allikian MJ, Hack AA, Mewborn S, Mayer U, McNally EM. Genetic compensation for sarcoglycan loss by integrin alpha7beta1 in muscle. J Cell Sci. 2004 Aug 01; 117(Pt 17):3821-30.
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Heydemann A, Huber JM, Kakkar R, Wheeler MT, McNally EM. Functional nitric oxide synthase mislocalization in cardiomyopathy. J Mol Cell Cardiol. 2004 Feb; 36(2):213-23.
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Krishnaswamy S, Duan SX, Von Moltke LL, Greenblatt DJ, Court MH. Validation of serotonin (5-hydroxtryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6. Drug Metab Dispos. 2003 Jan; 31(1):133-9.
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Li C, Fox CJ, Master SR, Bindokas VP, Chodosh LA, Thompson CB. Bcl-X(L) affects Ca(2+) homeostasis by altering expression of inositol 1,4,5-trisphosphate receptors. Proc Natl Acad Sci U S A. 2002 Jul 23; 99(15):9830-5.
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Jeyakumar LH, Ballester L, Cheng DS, McIntyre JO, Chang P, Olivey HE, Rollins-Smith L, Barnett JV, Murray K, Xin HB, Fleischer S. FKBP binding characteristics of cardiac microsomes from diverse vertebrates. Biochem Biophys Res Commun. 2001 Mar 09; 281(4):979-86.
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Musch MW, Goldstein L. Modulation of erythrocyte band 4.1 binding by volume expansion. J Exp Zool. 2001 Feb 15; 289(3):177-83.
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