CD4-Positive T-Lymphocytes
"CD4-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
| Descriptor ID |
D015496
|
| MeSH Number(s) |
A11.118.637.555.567.569.200 A15.145.229.637.555.567.569.200 A15.382.490.555.567.569.200
|
| Concept/Terms |
CD4-Positive T-Lymphocytes- CD4-Positive T-Lymphocytes
- CD4 Positive T Lymphocytes
- CD4-Positive T-Lymphocyte
- T-Lymphocyte, CD4-Positive
- T-Lymphocytes, CD4-Positive
- CD4-Positive Lymphocytes
- CD4-Positive Lymphocyte
- Lymphocyte, CD4-Positive
- Lymphocytes, CD4-Positive
- T4 Cells
- T4 Cell
- T4 Lymphocytes
- T4 Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "CD4-Positive T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "CD4-Positive T-Lymphocytes".
This graph shows the total number of publications written about "CD4-Positive T-Lymphocytes" by people in this website by year, and whether "CD4-Positive T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 2 | 4 |
| 1995 | 1 | 3 | 4 |
| 1996 | 1 | 1 | 2 |
| 1997 | 1 | 2 | 3 |
| 1998 | 1 | 4 | 5 |
| 1999 | 6 | 4 | 10 |
| 2000 | 3 | 7 | 10 |
| 2001 | 5 | 6 | 11 |
| 2002 | 4 | 2 | 6 |
| 2003 | 6 | 11 | 17 |
| 2004 | 5 | 4 | 9 |
| 2005 | 5 | 7 | 12 |
| 2006 | 7 | 7 | 14 |
| 2007 | 5 | 3 | 8 |
| 2008 | 7 | 6 | 13 |
| 2009 | 6 | 8 | 14 |
| 2010 | 9 | 10 | 19 |
| 2011 | 8 | 6 | 14 |
| 2012 | 11 | 13 | 24 |
| 2013 | 13 | 7 | 20 |
| 2014 | 8 | 6 | 14 |
| 2015 | 2 | 1 | 3 |
| 2016 | 7 | 8 | 15 |
| 2017 | 6 | 8 | 14 |
| 2018 | 4 | 1 | 5 |
| 2019 | 10 | 6 | 16 |
| 2020 | 5 | 7 | 12 |
| 2021 | 5 | 4 | 9 |
| 2022 | 2 | 3 | 5 |
| 2023 | 7 | 4 | 11 |
| 2024 | 3 | 4 | 7 |
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Below are the most recent publications written about "CD4-Positive T-Lymphocytes" by people in Profiles.
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Intranasal immunization with CPAF combined with ADU-S100 induces an effector CD4 T cell response and reduces bacterial burden following intravaginal infection with Chlamydia muridarum. Vaccine. 2025 Jan 01; 43(Pt 1):126526.
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Gene regulatory network inference from CRISPR perturbations in primary CD4+ T cells elucidates the genomic basis of immune disease. Cell Genom. 2024 Nov 13; 4(11):100671.
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CD4+ T cells with convergent TCR recombination reprogram stroma and halt tumor progression in adoptive therapy. Sci Immunol. 2024 Sep 13; 9(99):eadp6529.
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Characterization of double-negative T cells in colorectal cancers and their corresponding lymph nodes. Oncoimmunology. 2024; 13(1):2373530.
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Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity. Nat Commun. 2024 May 16; 15(1):4177.
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New Insights on Genes, Gluten, and Immunopathogenesis of Celiac Disease. Gastroenterology. 2024 Jun; 167(1):4-22.
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One CD4+TCR and One CD8+TCR Targeting Autochthonous Neoantigens Are Essential and Sufficient for Tumor Eradication. Clin Cancer Res. 2024 Apr 15; 30(8):1642-1654.
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Epithelial IFN? signalling and compartmentalized antigen presentation orchestrate gut immunity. Nature. 2023 Nov; 623(7989):1044-1052.
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Heterogeneity in allospecific T cell function in transplant-tolerant hosts determines susceptibility to rejection following infection. J Clin Invest. 2023 11 01; 133(21).
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Metabolic modulation of mitochondrial mass during CD4+ T cell activation. Cell Chem Biol. 2023 09 21; 30(9):1064-1075.e8.