CD4-Positive T-Lymphocytes
"CD4-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
| Descriptor ID |
D015496
|
| MeSH Number(s) |
A11.118.637.555.567.569.200 A15.145.229.637.555.567.569.200 A15.382.490.555.567.569.200
|
| Concept/Terms |
CD4-Positive T-Lymphocytes- CD4-Positive T-Lymphocytes
- CD4 Positive T Lymphocytes
- CD4-Positive T-Lymphocyte
- T-Lymphocyte, CD4-Positive
- T-Lymphocytes, CD4-Positive
- CD4-Positive Lymphocytes
- CD4-Positive Lymphocyte
- Lymphocyte, CD4-Positive
- Lymphocytes, CD4-Positive
- T4 Cells
- T4 Cell
- T4 Lymphocytes
- T4 Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "CD4-Positive T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "CD4-Positive T-Lymphocytes".
This graph shows the total number of publications written about "CD4-Positive T-Lymphocytes" by people in this website by year, and whether "CD4-Positive T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 4 | 2 | 6 |
| 1994 | 3 | 2 | 5 |
| 1995 | 1 | 3 | 4 |
| 1996 | 1 | 2 | 3 |
| 1997 | 1 | 2 | 3 |
| 1998 | 1 | 4 | 5 |
| 1999 | 6 | 4 | 10 |
| 2000 | 3 | 7 | 10 |
| 2001 | 4 | 6 | 10 |
| 2002 | 4 | 2 | 6 |
| 2003 | 6 | 12 | 18 |
| 2004 | 5 | 4 | 9 |
| 2005 | 6 | 7 | 13 |
| 2006 | 7 | 6 | 13 |
| 2007 | 5 | 3 | 8 |
| 2008 | 6 | 5 | 11 |
| 2009 | 4 | 7 | 11 |
| 2010 | 8 | 9 | 17 |
| 2011 | 8 | 6 | 14 |
| 2012 | 10 | 13 | 23 |
| 2013 | 13 | 6 | 19 |
| 2014 | 7 | 4 | 11 |
| 2015 | 2 | 1 | 3 |
| 2016 | 7 | 7 | 14 |
| 2017 | 6 | 7 | 13 |
| 2018 | 4 | 1 | 5 |
| 2019 | 10 | 6 | 16 |
| 2020 | 5 | 6 | 11 |
| 2021 | 2 | 4 | 6 |
| 2022 | 2 | 2 | 4 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "CD4-Positive T-Lymphocytes" by people in Profiles.
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The endogenous repertoire harbors self-reactive CD4+ T cell clones that adopt a follicular helper T cell-like phenotype at steady state. Nat Immunol. 2023 Mar; 24(3):487-500.
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Longitudinal analysis reveals age-related changes in the T cell receptor repertoire of human T cell subsets. J Clin Invest. 2022 09 01; 132(17).
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A conserved Bacteroidetes antigen induces anti-inflammatory intestinal T lymphocytes. Science. 2022 08 05; 377(6606):660-666.
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Innate riddle of CD4+ T?cells and the control of enteric infections. Immunity. 2022 07 12; 55(7):1145-1147.
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Linked sensitization by memory CD4+ T cells prevents costimulation blockade-induced transplantation tolerance. JCI Insight. 2022 06 08; 7(11).
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Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T?cells influence effector potential. Cell Rep. 2021 11 30; 37(9):110064.
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Lung Epithelial Signaling Mediates Early Vaccine-Induced CD4+ T Cell Activation and Mycobacterium tuberculosis Control. mBio. 2021 08 31; 12(4):e0146821.
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A local regulatory T?cell feedback circuit maintains immune homeostasis by pruning self-activated T?cells. Cell. 2021 07 22; 184(15):3981-3997.e22.
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All-trans retinoic acid overcomes solid tumor radioresistance by inducing inflammatory macrophages. Sci Immunol. 2021 06 15; 6(60).
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Altered selection on a single self-ligand promotes susceptibility to organ-specific T cell infiltration. J Exp Med. 2021 06 07; 218(6).