CD4-Positive T-Lymphocytes
"CD4-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes.
| Descriptor ID |
D015496
|
| MeSH Number(s) |
A11.118.637.555.567.569.200 A15.145.229.637.555.567.569.200 A15.382.490.555.567.569.200
|
| Concept/Terms |
CD4-Positive T-Lymphocytes- CD4-Positive T-Lymphocytes
- CD4 Positive T Lymphocytes
- CD4-Positive T-Lymphocyte
- T-Lymphocyte, CD4-Positive
- T-Lymphocytes, CD4-Positive
- CD4-Positive Lymphocytes
- CD4-Positive Lymphocyte
- Lymphocyte, CD4-Positive
- Lymphocytes, CD4-Positive
- T4 Cells
- T4 Cell
- T4 Lymphocytes
- T4 Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "CD4-Positive T-Lymphocytes".
Below are MeSH descriptors whose meaning is more specific than "CD4-Positive T-Lymphocytes".
This graph shows the total number of publications written about "CD4-Positive T-Lymphocytes" by people in this website by year, and whether "CD4-Positive T-Lymphocytes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1997 | 1 | 3 | 4 |
| 1998 | 1 | 4 | 5 |
| 1999 | 6 | 4 | 10 |
| 2000 | 2 | 7 | 9 |
| 2001 | 5 | 6 | 11 |
| 2002 | 5 | 2 | 7 |
| 2003 | 6 | 11 | 17 |
| 2004 | 5 | 5 | 10 |
| 2005 | 5 | 7 | 12 |
| 2006 | 7 | 7 | 14 |
| 2007 | 5 | 3 | 8 |
| 2008 | 7 | 7 | 14 |
| 2009 | 6 | 8 | 14 |
| 2010 | 9 | 10 | 19 |
| 2011 | 8 | 6 | 14 |
| 2012 | 11 | 13 | 24 |
| 2013 | 15 | 7 | 22 |
| 2014 | 12 | 6 | 18 |
| 2015 | 5 | 1 | 6 |
| 2016 | 8 | 11 | 19 |
| 2017 | 6 | 8 | 14 |
| 2018 | 5 | 2 | 7 |
| 2019 | 11 | 6 | 17 |
| 2020 | 6 | 11 | 17 |
| 2021 | 6 | 5 | 11 |
| 2022 | 2 | 4 | 6 |
| 2023 | 7 | 4 | 11 |
| 2024 | 4 | 5 | 9 |
| 2025 | 8 | 1 | 9 |
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Below are the most recent publications written about "CD4-Positive T-Lymphocytes" by people in Profiles.
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Prediction and characterization of genetically regulated expression of asthma tissues from African-ancestry populations. J Allergy Clin Immunol. 2026 Jan; 157(1):253-261.
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Cell-intrinsic CD4 T cell tolerance: a new frontier in therapy? Trends Immunol. 2025 Sep; 46(9):624-634.
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Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation. Nature. 2025 Jul; 643(8071):509-518.
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Mutant p53-specific CD8TCR-therapy combined with a CD4TCR prevents relapse of cancer and outgrowth of micrometastases. Oncoimmunology. 2025 Dec; 14(1):2514041.
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Mitochondrial fatty acid synthesis and MECR regulate CD4+ T cell function and oxidative metabolism. J Immunol. 2025 May 01; 214(5):958-976.
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Deconvoluting TCR-dependent and -independent activation is vital for reliable Ag-specific CD4+ T cell characterization by AIM assay. Sci Adv. 2025 Apr 25; 11(17):eadv3491.
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Prevention of tuberculosis in cynomolgus macaques by an attenuated Mycobacterium tuberculosis vaccine candidate. Nat Commun. 2025 Feb 25; 16(1):1957.
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Cutting to the chase: Pruning alloreactive T cells. Immunity. 2025 Feb 11; 58(2):270-272.
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Enrichment of CD4+ and CD8+ T lymphocytes with a column-free flow-based device for clinical cell manufacturing. Cytotherapy. 2025 Apr; 27(4):534-543.
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Central control of dynamic gene circuits governs T cell rest and activation. Nature. 2025 Jan; 637(8047):930-939.