 Myelin Sheath
"Myelin Sheath" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The lipid-rich sheath surrounding AXONS in both the central and peripheral nervous systems. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.
| Descriptor ID |
D009186
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| MeSH Number(s) |
A08.637.600.500 A08.637.800.500 A08.663.542.512.560 A08.800.800.690.500 A10.755.503 A11.284.149.165.600 A11.650.600.500 A11.650.800.500 A11.671.514.553
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| Concept/Terms |
Myelin Sheath- Myelin Sheath
- Myelin Sheaths
- Sheath, Myelin
- Sheaths, Myelin
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Below are MeSH descriptors whose meaning is more general than "Myelin Sheath".
Below are MeSH descriptors whose meaning is more specific than "Myelin Sheath".
This graph shows the total number of publications written about "Myelin Sheath" by people in this website by year, and whether "Myelin Sheath" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1982 | 0 | 2 | 2 | | 1983 | 1 | 3 | 4 | | 1984 | 0 | 2 | 2 | | 1985 | 1 | 0 | 1 | | 1986 | 2 | 0 | 2 | | 1988 | 2 | 0 | 2 | | 1989 | 1 | 0 | 1 | | 1990 | 2 | 1 | 3 | | 1991 | 1 | 0 | 1 | | 1992 | 3 | 1 | 4 | | 1993 | 1 | 2 | 3 | | 1996 | 2 | 1 | 3 | | 1998 | 7 | 1 | 8 | | 1999 | 3 | 3 | 6 | | 2000 | 3 | 1 | 4 | | 2002 | 5 | 1 | 6 | | 2003 | 1 | 0 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 4 | 1 | 5 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 2 | 1 | 3 | | 2009 | 2 | 1 | 3 | | 2010 | 5 | 0 | 5 | | 2011 | 0 | 3 | 3 | | 2013 | 3 | 0 | 3 | | 2014 | 4 | 0 | 4 | | 2015 | 3 | 1 | 4 | | 2016 | 3 | 1 | 4 | | 2017 | 2 | 1 | 3 | | 2018 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Myelin Sheath" by people in Profiles.
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Elitt MS, Shick HE, Madhavan M, Allan KC, Clayton BLL, Weng C, Miller TE, Factor DC, Barbar L, Nawash BS, Nevin ZS, Lager AM, Li Y, Jin F, Adams DJ, Tesar PJ. Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease. Stem Cell Reports. 2018 09 11; 11(3):711-726.
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Lu J, Synowiec S, Lu L, Yu Y, Bretherick T, Takada S, Yarnykh V, Caplan J, Caplan M, Claud EC, Drobyshevsky A. Microbiota influence the development of the brain and behaviors in C57BL/6J mice. PLoS One. 2018; 13(8):e0201829.
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McKenzie AT, Moyon S, Wang M, Katsyv I, Song WM, Zhou X, Dammer EB, Duong DM, Aaker J, Zhao Y, Beckmann N, Wang P, Zhu J, Lah JJ, Seyfried NT, Levey AI, Katsel P, Haroutunian V, Schadt EE, Popko B, Casaccia P, Zhang B. Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease. Mol Neurodegener. 2017 11 06; 12(1):82.
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Dyer EL, Gray Roncal W, Prasad JA, Fernandes HL, Gürsoy D, De Andrade V, Fezzaa K, Xiao X, Vogelstein JT, Jacobsen C, Körding KP, Kasthuri N. Quantifying Mesoscale Neuroanatomy Using X-Ray Microtomography. eNeuro. 2017 Sep-Oct; 4(5).
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Clayton BL, Huang A, Dukala D, Soliven B, Popko B. Neonatal Hypoxia Results in Peripheral Nerve Abnormalities. Am J Pathol. 2017 Feb; 187(2):245-251.
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Elbaz B. Activity-Dependent Myelination Shapes Conduction Velocity. J Neurosci. 2016 11 16; 36(46):11585-11586.
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Elbaz B, Traka M, Kunjamma RB, Dukala D, Brosius Lutz A, Anton ES, Barres BA, Soliven B, Popko B. Adenomatous polyposis coli regulates radial axonal sorting and myelination in the PNS. Development. 2016 07 01; 143(13):2356-66.
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Pusic KM, Pusic AD, Kraig RP. Environmental Enrichment Stimulates Immune Cell Secretion of Exosomes that Promote CNS Myelination and May Regulate Inflammation. Cell Mol Neurobiol. 2016 Apr; 36(3):313-325.
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Hunter SF, Bowen JD, Reder AT. The Direct Effects of Fingolimod in the Central Nervous System: Implications for Relapsing Multiple Sclerosis. CNS Drugs. 2016 Feb; 30(2):135-47.
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Traka M, Podojil JR, McCarthy DP, Miller SD, Popko B. Oligodendrocyte death results in immune-mediated CNS demyelination. Nat Neurosci. 2016 Jan; 19(1):65-74.
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