"Microglia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The third type of glial cell, along with astrocytes and oligodendrocytes (which together form the macroglia). Microglia vary in appearance depending on developmental stage, functional state, and anatomical location; subtype terms include ramified, perivascular, ameboid, resting, and activated. Microglia clearly are capable of phagocytosis and play an important role in a wide spectrum of neuropathologies. They have also been suggested to act in several other roles including in secretion (e.g., of cytokines and neural growth factors), in immunological processing (e.g., antigen presentation), and in central nervous system development and remodeling.
| Descriptor ID |
D017628
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| MeSH Number(s) |
A08.637.400 A11.650.400
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Microglia".
Below are MeSH descriptors whose meaning is more specific than "Microglia".
This graph shows the total number of publications written about "Microglia" by people in this website by year, and whether "Microglia" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1998 | 2 | 1 | 3 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2007 | 2 | 0 | 2 |
| 2008 | 4 | 1 | 5 |
| 2009 | 2 | 2 | 4 |
| 2010 | 2 | 3 | 5 |
| 2011 | 2 | 2 | 4 |
| 2012 | 2 | 6 | 8 |
| 2013 | 2 | 1 | 3 |
| 2014 | 2 | 1 | 3 |
| 2015 | 0 | 2 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 4 | 3 | 7 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 3 | 5 |
| 2020 | 1 | 4 | 5 |
| 2021 | 1 | 6 | 7 |
| 2022 | 2 | 1 | 3 |
| 2023 | 1 | 4 | 5 |
| 2024 | 4 | 7 | 11 |
| 2025 | 5 | 2 | 7 |
| 2026 | 3 | 1 | 4 |
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Below are the most recent publications written about "Microglia" by people in Profiles.
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Human neural organoid modeling of diffuse midline glioma captures the complexity of patient tumors. J Neurooncol. 2026 May 07; 177(3).
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Microglial fructose metabolism is essential for glioblastoma growth. Proc Natl Acad Sci U S A. 2026 Mar 24; 123(12):e2521256123.
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Amyloid precursor protein is a subunit of microglial Hv1 channels. Curr Opin Immunol. 2026 Jun; 100:102751.
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Microglial TBK1 Signaling Promotes Breast Cancer Brain Metastasis. Cancer Res. 2026 01 02; 86(1):12-21.
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Ethanol induces neuroimmune dysregulation and soluble TREM2 generation in a human iPSC neuron, astrocyte, microglia triculture model. Alcohol. 2026 02; 130:57-72.
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PICALM Alzheimer's risk allele causes aberrant lipid droplets in microglia. Nature. 2025 10; 646(8087):1178-1186.
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The knockout of Moesin leads to excess microglia-mediated synaptic pruning and impairs social novelty in a mouse model. Cell Rep. 2025 Aug 26; 44(8):116012.
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Glycoprotein NMB mediates bidirectional GSC-TAM interactions to promote tumor progression. JCI Insight. 2025 07 08; 10(13).
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Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation. Nature. 2025 07; 643(8071):509-518.
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Targeting C1q prevents microglia-mediated synaptic removal in neuropathic pain. Nat Commun. 2025 May 17; 16(1):4590.