 Nucleoside-Diphosphate Kinase
"Nucleoside-Diphosphate Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that is found in mitochondria and in the soluble cytoplasm of cells. It catalyzes reversible reactions of a nucleoside triphosphate, e.g., ATP, with a nucleoside diphosphate, e.g., UDP, to form ADP and UTP. Many nucleoside diphosphates can act as acceptor, while many ribo- and deoxyribonucleoside triphosphates can act as donor. EC 2.7.4.6.
| Descriptor ID |
D009701
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| MeSH Number(s) |
D08.811.913.696.650.550
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| Concept/Terms |
Nucleoside-Diphosphate Kinase- Nucleoside-Diphosphate Kinase
- Kinase, Nucleoside-Diphosphate
- Nucleoside Diphosphate Kinase
- Nucleoside Diphosphokinases
- Diphosphokinases, Nucleoside
- Deoxynucleoside Diphosphate Kinases
- Diphosphate Kinases, Deoxynucleoside
- Kinases, Deoxynucleoside Diphosphate
- Nucleoside-Diphosphate Kinases
- Kinases, Nucleoside-Diphosphate
- Nucleoside Diphosphate Kinases
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This graph shows the total number of publications written about "Nucleoside-Diphosphate Kinase" by people in this website by year, and whether "Nucleoside-Diphosphate Kinase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 | | 1996 | 1 | 1 | 2 | | 1998 | 1 | 0 | 1 | | 1999 | 2 | 1 | 3 | | 2000 | 2 | 1 | 3 | | 2007 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nucleoside-Diphosphate Kinase" by people in Profiles.
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Kolli BK, Kostal J, Zaborina O, Chakrabarty AM, Chang KP. Leishmania-released nucleoside diphosphate kinase prevents ATP-mediated cytolysis of macrophages. Mol Biochem Parasitol. 2008 Apr; 158(2):163-75.
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Welch DR, Steeg PS, Rinker-Schaeffer CW. Molecular biology of breast cancer metastasis. Genetic regulation of human breast carcinoma metastasis. Breast Cancer Res. 2000; 2(6):408-16.
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Melnikov A, Zaborina O, Dhiman N, Prabhakar BS, Chakrabarty AM, Hendrickson W. Clinical and environmental isolates of Burkholderia cepacia exhibit differential cytotoxicity towards macrophages and mast cells. Mol Microbiol. 2000 Jun; 36(6):1481-93.
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Heimann R, Lan F, McBride R, Hellman S. Separating favorable from unfavorable prognostic markers in breast cancer: the role of E-cadherin. Cancer Res. 2000 Jan 15; 60(2):298-304.
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Zhu J, Tseng YH, Kantor JD, Rhodes CJ, Zetter BR, Moyers JS, Kahn CR. Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation. Proc Natl Acad Sci U S A. 1999 Dec 21; 96(26):14911-8.
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Zaborina O, Misra N, Kostal J, Kamath S, Kapatral V, El-Idrissi ME, Prabhakar BS, Chakrabarty AM. P2Z-Independent and P2Z receptor-mediated macrophage killing by Pseudomonas aeruginosa isolated from cystic fibrosis patients. Infect Immun. 1999 Oct; 67(10):5231-42.
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Zaborina O, Li X, Cheng G, Kapatral V, Chakrabarty AM. Secretion of ATP-utilizing enzymes, nucleoside diphosphate kinase and ATPase, by Mycobacterium bovis BCG: sequestration of ATP from macrophage P2Z receptors? Mol Microbiol. 1999 Mar; 31(5):1333-43.
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Heimann R, Ferguson DJ, Hellman S. The relationship between nm23, angiogenesis, and the metastatic proclivity of node-negative breast cancer. Cancer Res. 1998 Jul 01; 58(13):2766-71.
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Yang LM, Lamppa GK. Rapid purification of a chloroplast nucleoside diphosphate kinase using CoA-affinity chromatography. Biochim Biophys Acta. 1996 May 23; 1294(2):99-102.
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Kowluru A, Seavey SE, Rhodes CJ, Metz SA. A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent beta cells. Biochem J. 1996 Jan 01; 313 ( Pt 1):97-107.
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