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Christopher J. Rhodes

TitleEmeritus/Emerita, Professor
InstitutionUniversity of Chicago
DepartmentMedicine-Endocrinology
AddressChicago IL 60637
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    Collapse Research 
    Collapse research activities and funding
    R01DK099359     (RHODES, CHRISTOPHER J)Jul 1, 2015 - May 31, 2019
    NIH
    Central Control of Pancreatic Islet Function
    Role: Principal Investigator
    T32DK087703     (RHODES, CHRISTOPHER J)Jul 1, 2010 - Jun 30, 2016
    NIH
    An Interdisciplinary Molecular Metabolism Training Program
    Role: Principal Investigator
    R13DK060582     (HUTTON, JOHN C)Sep 20, 2001 - Aug 31, 2008
    NIH
    Western Region Islet Study Group
    Role: Co-Principal Investigator
    R01DK055267     (RHODES, CHRISTOPHER J)Sep 30, 1998 - Jun 30, 2015
    NIH
    Mitogenic Signal Transduction in Pancreatic Beta-Cells
    Role: Principal Investigator
    R01DK050610     (RHODES, CHRISTOPHER J)Feb 15, 1996 - May 31, 2015
    NIH
    Metabolic Control of Proinsulin Biosynthesis Translation
    Role: Principal Investigator
    R56DK050610     (RHODES, CHRISTOPHER J)Feb 15, 1996 - May 31, 2010
    NIH
    Metabolic Control of Proinsulin Biosynthesis Translation
    Role: Principal Investigator
    R01DK047919     (RHODES, CHRISTOPHER J)May 1, 1994 - Apr 30, 2007
    NIH
    Metabolic Control of Insulin Exocytosis
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Finlay D, Patel S, Dickson LM, Shpiro N, Marquez R, Rhodes CJ, Sutherland C. Correction: Glycogen Synthase Kinase-3 regulates IGFBP-1 gene transcription through the Thymine-rich Insulin Response Element. BMC Mol Cell Biol. 2024 Dec 03; 25(1):25. PMID: 39627717; PMCID: PMC11613617.
      Citations:    Fields:    
    2. La Merrill MA, Smith MT, McHale CM, Heindel JJ, Atlas E, Cave MC, Collier D, Guyton KZ, Koliwad S, Nadal A, Rhodes CJ, Sargis RM, Zeise L, Blumberg B. Consensus on the key characteristics of metabolism disruptors. Nat Rev Endocrinol. 2024 Nov 29. PMID: 39613954.
      Citations:    Fields:    
    3. Wean J, Kowalsky AH, Laker R, Will S, Drucker DJ, Rhodes CJ, Seeley RJ. Specific loss of GIPR signaling in GABAergic neurons enhances GLP-1R agonist-induced body weight loss. Mol Metab. 2024 Nov 26; 102074. PMID: 39612941.
      Citations:    Fields:    
    4. Kazmirczak F, Vogel NT, Prisco SZ, Patterson MT, Annis J, Moon RT, Hartweck LM, Mendelson JB, Kim M, Calixto Mancipe N, Markowski T, Higgins L, Guerrero C, Kremer B, Blake ML, Rhodes CJ, Williams JW, Brittain EL, Prins KW, Vogel NT, Prisco SZ, Patterson MT, Annis J, Moon RT, Hartweck LM, Mendelson JB, Kim M, Calixto Mancipe N, Markowski T, Higgins L, Guerrero C, Kremer B, Blake ML, Williams JW, Brittain EL, Prins KW. Ferroptosis-Mediated Inflammation Promotes Pulmonary Hypertension. Circ Res. 2024 Nov 08; 135(11):1067-1083. PMID: 39421926; PMCID: PMC11560515.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    5. Harbaum L, Hennigs JK, Pott J, Ostermann J, Sinning CR, Sau A, Sieliwonczyk E, Ng FS, Rhodes CJ, Tello K, Klose H, Gräf S, Wilkins MR. Sex-specific Genetic Determinants of Right Ventricular Structure and Function. Am J Respir Crit Care Med. 2024 Oct 07. PMID: 39374572.
      Citations:    Fields:    
    6. Kazmirczak F, Vogel NT, Prisco SZ, Patterson MT, Annis J, Moon RT, Hartweck LM, Mendelson JB, Kim M, Mancipe NC, Markowski T, Higgins L, Guerrero C, Kremer B, Blake ML, Rhodes CJ, Williams JW, Brittain EL, Prins KW. Ferroptosis Integrates Mitochondrial Derangements and Pathological Inflammation to Promote Pulmonary Hypertension. bioRxiv. 2024 Sep 23. PMID: 36712076; PMCID: PMC9882268.
      Citations:    
    7. Gomez-Arroyo J, Houweling AC, Bogaard HJ, Aman J, Kitzmiller JA, Porollo A, Dooijes D, Meijboom LJ, Hale P, Pauciulo MW, Hong J, Zhu N, Welch C, Shen Y, Zacharias WJ, McCormack FX, Aldred MA, Weirauch MT, Graf S, Rhodes C, Chung WK, Whitsett JA, Martin LJ, Kalinichenko VV, Nichols WC. Role of Forkhead box F1 in the Pathobiology of Pulmonary Arterial Hypertension. bioRxiv. 2024 Sep 22. PMID: 39345371; PMCID: PMC11429893.
      Citations:    
    8. Hong J, Medzikovic L, Sun W, Wong B, Ruffenach G, Rhodes CJ, Brownstein A, Liang LL, Aryan L, Li M, Vadgama A, Kurt Z, Schwantes-An TH, Mickler EA, Gräf S, Eyries M, Lutz KA, Pauciulo MW, Trembath RC, Perros F, Montani D, Morrell NW, Soubrier F, Wilkins MR, Nichols WC, Aldred MA, Desai AA, Trégouët DA, Umar S, Saggar R, Channick R, Tuder RM, Geraci MW, Stearman RS, Yang X, Eghbali M, Hong J, Medzikovic L, Sun W, Wong B, Ruffenach G, Brownstein A, Liang LL, Aryan L, Li M, Vadgama A, Umar S, Saggar R, Channick R, Yang X, Eghbali M. Integrative Multiomics in the Lung Reveals a Protective Role of Asporin in Pulmonary Arterial Hypertension. Circulation. 2024 Oct 15; 150(16):1268-1287. PMID: 39167456; PMCID: PMC11473243.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    9. Liley J, Newnham M, Bleda M, Bunclark K, Auger W, Barbera JA, Bogaard H, Delcroix M, Fernandes TM, Howard L, Jenkins D, Lang I, Mayer E, Rhodes C, Simpson M, Southgate L, Trembath R, Wharton J, Wilkins MR, Gräf S, Morrell N, Zaba JP, Toshner M. Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism. Am J Respir Crit Care Med. 2024 06 15; 209(12):1477-1485. PMID: 38470220; PMCID: PMC11208965.
      Citations: 2     Fields:    Translation:Humans
    10. Woolf B, Wilkins MR, Toshner M, Gill D, Burgess S, Rhodes CJ, Perry JA, Hong CC. Multi-biobank summary data Mendelian randomisation does not support a causal effect of IL-6 signalling on risk of pulmonary arterial hypertension. Eur Respir J. 2024 Apr; 63(4). PMID: 38453257; PMCID: PMC10991834.
      Citations: 1     Fields:    Translation:Humans
    11. Alhathli E, Julian T, Girach ZUA, Thompson AAR, Rhodes C, Gräf S, Errington N, Wilkins MR, Lawrie A, Wang D, Cooper-Knock J. Mendelian Randomization Study With Clinical Follow-Up Links Metabolites to Risk and Severity of Pulmonary Arterial Hypertension. J Am Heart Assoc. 2024 Mar 19; 13(6):e032256. PMID: 38456412; PMCID: PMC11010003.
      Citations: 6     Fields:    Translation:Humans
    12. Ratkova E, Kajani S, Laker RC, Will S, Rhodes CJ. Hepatic glucagon action: beyond glucose mobilization. Physiol Rev. 2024 Jul 01; 104(3):1021-1060. PMID: 38300523.
      Citations: 2     Fields:    Translation:HumansAnimals
    13. Tai YY, Yu Q, Tang Y, Sun W, Kelly NJ, Okawa S, Zhao J, Schwantes-An TH, Lacoux C, Torrino S, Al Aaraj Y, El Khoury W, Negi V, Liu M, Corey CG, Belmonte F, Vargas SO, Schwartz B, Bhat B, Chau BN, Karnes JH, Satoh T, Barndt RJ, Wu H, Parikh VN, Wang J, Zhang Y, McNamara D, Li G, Speyer G, Wang B, Shiva S, Kaufman B, Kim S, Gomez D, Mari B, Cho MH, Boueiz A, Pauciulo MW, Southgate L, Trembath RC, Sitbon O, Humbert M, Graf S, Morrell NW, Rhodes CJ, Wilkins MR, Nouraie M, Nichols WC, Desai AA, Bertero T, Chan SY. Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension. Sci Transl Med. 2024 01 10; 16(729):eadd2029. PMID: 38198571; PMCID: PMC10947529.
      Citations: 2     Fields:    Translation:HumansAnimals
    14. Ulrich A, Wu Y, Draisma H, Wharton J, Swietlik EM, Cebola I, Vasilaki E, Balkhiyarova Z, Jarvelin MR, Auvinen J, Herzig KH, Coghlan JG, Lordan J, Church C, Howard LS, Pepke-Zaba J, Toshner M, Wort SJ, Kiely DG, Condliffe R, Lawrie A, Gräf S, Morrell NW, Wilkins MR, Prokopenko I, Rhodes CJ. Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension. Nat Commun. 2024 Jan 06; 15(1):330. PMID: 38184627; PMCID: PMC10771427.
      Citations: 1     Fields:    Translation:HumansCells
    15. Kariotis S, Tan PF, Lu H, Rhodes CJ, Wilkins MR, Lawrie A, Wang D. Omada: robust clustering of transcriptomes through multiple testing. Gigascience. 2024 01 02; 13. PMID: 38991852; PMCID: PMC11238428.
      Citations: 1     Fields:    Translation:HumansCells
    16. Walters R, Vasilaki E, Wilkins MR, Zhao L, Rhodes CJ. Response by Walters et al to Letter Regarding Article, "SOX17 Enhancer Variants Disrupt Transcription Factor Binding and Enhancer Inactivity Drives Pulmonary Hypertension". Circulation. 2023 11 28; 148(22):1825-1826. PMID: 38011243.
      Citations:    Fields:    Translation:HumansCells
    17. Merz JJ, Barnard P, Rees WE, Smith D, Maroni M, Rhodes CJ, Dederer JH, Bajaj N, Joy MK, Wiedmann T, Sutherland R. World scientists' warning: The behavioural crisis driving ecological overshoot. Sci Prog. 2023 Jul-Sep; 106(3):368504231201372. PMID: 37728669; PMCID: PMC10515534.
      Citations: 5     Fields:    Translation:Humans
    18. Jomova K, Cvik M, Lauro P, Valko M, Cizmar E, Alomar SY, Alwasel SH, Oleksak P, Chrienova Z, Nepovimova E, Kuca K, Rhodes CJ. The role of redox active copper(II) on antioxidant properties of the flavonoid baicalein: DNA protection under Cu(II)-Fenton reaction and Cu(II)-ascorbate system conditions. J Inorg Biochem. 2023 08; 245:112244. PMID: 37178556.
      Citations: 3     Fields:    Translation:Cells
    19. Andersen MK, Bork-Jensen J, Jonsson AE, Stinson SE, Sandholt CH, Thodberg M, Pikkupeura LM, Ongstad EL, Grarup N, Astrup A, Pedersen O, Williams K, Linneberg A, Grimsby J, Rhodes CJ, Hansen T, Ängquist L, Barrès R, Sørensen TIA. Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity. Diabetes Care. 2023 05 01; 46(5):985-992. PMID: 36809463.
      Citations: 1     Fields:    Translation:Humans
    20. Rhodes CJ, Howard LS, Wilkins MR, Guignabert C, Savale L, Boucly A, Thuillet R, Tu L, Ottaviani M, De Groote P, Prévot G, Bergot E, Bourdin A, Fadel E, Beurnier A, Roche A, Jevnikar M, Jaïs X, Montani D, Sitbon O, Humbert M. Serum and Pulmonary Expression Profiles of the Activin Signaling System in Pulmonary Arterial Hypertension. Circulation. 2023 06 13; 147(24):1809-1822. PMID: 37096577.
      Citations: 20     Fields:    Translation:Humans
    21. Walters R, Vasilaki E, Aman J, Chen CN, Wu Y, Ashek A, Dubois O, Zhao L, Sabrin F, Ferrer J, Morrell NW, Wilkins MR, Zhao L, Rhodes CJ, Cebola I, Liang OD, Klinger JR. SOX17 Enhancer Variants Disrupt Transcription Factor Binding And Enhancer Inactivity Drives Pulmonary Hypertension. Circulation. 2023 05 23; 147(21):1606-1621. PMID: 37066790; PMCID: PMC7614572.
      Citations: 6     Fields:    Translation:AnimalsCells
    22. Szydlowska M, Lasky G, Oldham S, Rivera C, Ford M, Sellman BR, Rhodes CJ, Cohen TS. Restoring polyamine levels by supplementation of spermidine modulates hepatic immune landscape in murine model of NASH. Biochim Biophys Acta Mol Basis Dis. 2023 08; 1869(6):166697. PMID: 37054999.
      Citations: 1     Fields:    Translation:HumansAnimals
    23. Bourdin A, Rhodes C, Wilkins MR, Boucly A, Tu L, Guignabert C, De Groote P, Prévot G, Bergot E, Beurnier A, Roche A, Jevnikar M, Jaïs X, Montani D, Humbert M, Sitbon O, Savale L. Cytokines as prognostic biomarkers in pulmonary arterial hypertension. Eur Respir J. 2023 03; 61(3). PMID: 36549710.
      Citations: 11     Fields:    Translation:Humans
    24. Stinson SE, Jonsson AE, Andersen MK, Holm LA, Fonvig CE, Huang Y, Stankevic E, Ongstad EL, Gaddipati R, Grimsby J, Rhodes CJ, Pedersen O, Holm JC, Hansen T, Lund MAV, Juel HB, Ängquist L, Sørensen TIA, Christiansen M. High Plasma Levels of Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 Are Associated With Inflammation and Cardiometabolic Risk Profiles in Pediatric Overweight and Obesity. J Am Heart Assoc. 2023 02 07; 12(3):e8145. PMID: 36695299; PMCID: PMC9973661.
      Citations: 5     Fields:    Translation:Humans
    25. Hong J, Wong B, Rhodes CJ, Kurt Z, Schwantes-An TH, Mickler EA, Lutz KA, Pauciulo MW, Trembath RC, Montani D, Morrell NW, Wilkins MR, Nichols WC, Aldred MA, Desai AA, Tuder RM, Geraci MW, Eghbali M, Stearman RS, Yang X, Gräf S, Eyries M, Trégouët DA. Integrative Multiomics to Dissect the Lung Transcriptional Landscape of Pulmonary Arterial Hypertension. bioRxiv. 2023 Jan 16. PMID: 36712057; PMCID: PMC9882207.
      Citations: 2     
    26. Ali MK, Tian X, Zhao L, Schimmel K, Rhodes CJ, Wilkins MR, Nicolls MR, Spiekerkoetter EF. PTPN1 Deficiency Modulates BMPR2 Signaling and Induces Endothelial Dysfunction in Pulmonary Arterial Hypertension. Cells. 2023 01 14; 12(2). PMID: 36672250; PMCID: PMC9857213.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    27. Aman J, Morrell NW, Rhodes CJ, Wilkins MR, Bogaard HJ. The SOX17 phenotype in pulmonary arterial hypertension: lessons for pathobiology and clinical management. Eur Respir J. 2022 12; 60(6). PMID: 37651375.
      Citations:    Fields:    Translation:Humans
    28. Kariotis S, Jammeh E, Swietlik EM, Pickworth JA, Rhodes CJ, Otero P, Wharton J, Iremonger J, Dunning MJ, Pandya D, Mascarenhas TS, Errington N, Thompson AAR, Romanoski CE, Rischard F, Garcia JGN, Yuan JX, An TS, Desai AA, Coghlan G, Lordan J, Corris PA, Howard LS, Condliffe R, Kiely DG, Church C, Pepke-Zaba J, Toshner M, Wort S, Morrell NW, Wilkins MR, Lawrie A, Wang D, UK National PAH Cohort Study Consortium, Gräf S. Author Correction: Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood. Nat Commun. 2022 Nov 25; 13(1):7276. PMID: 36433938; PMCID: PMC9700755.
      Citations:    Fields:    
    29. Hirsch K, Nolley S, Ralph DD, Zheng Y, Altemeier WA, Rhodes CJ, Morrell NW, Wilkins MR, Leary PJ, Rayner SG. Circulating markers of inflammation and angiogenesis and clinical outcomes across subtypes of pulmonary arterial hypertension. J Heart Lung Transplant. 2023 02; 42(2):173-182. PMID: 36470771; PMCID: PMC9840657.
      Citations: 9     Fields:    Translation:Humans
    30. Ainscough AJ, Smith TJ, Haensel M, Rhodes CJ, Fellows A, Whitwell HJ, Vasilaki E, Gray K, Freeman A, Howard LS, Wharton J, Dunmore B, Upton PD, Wilkins MR, Edel JB, Wojciak-Stothard B. An organ-on-chip model of pulmonary arterial hypertension identifies a BMPR2-SOX17-prostacyclin signalling axis. Commun Biol. 2022 11 07; 5(1):1192. PMID: 36344664; PMCID: PMC9640600.
      Citations: 6     Translation:Humans
    31. Jomova K, Makova M, Alomar SY, Alwasel SH, Nepovimova E, Kuca K, Rhodes CJ, Valko M. Essential metals in health and disease. Chem Biol Interact. 2022 Nov 01; 367:110173. PMID: 36152810.
      Citations: 135     Fields:    Translation:Humans
    32. Seeley RJ, Rhodes CJ. Who knew? PPARs may act in the brain too. Nat Metab. 2022 08; 4(8):965-966. PMID: 35995998.
      Citations:    Fields:    
    33. Selle J, Dinger K, Jentgen V, Zanetti D, Will J, Georgomanolis T, Vohlen C, Wilke R, Mohr J, V Koningsbruggen-Rietschel S, Rhodes CJ, Ulrich A, Hirani D, Nestler T, Odenthal M, Mahabir E, Nayakanti S, Dabral S, Wunderlich T, Priest J, Alejandre Alcazar MA, Kojonazarov B, Klymenko O, Seeger W, Dötsch J, Pullamsetti SS. Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life. Nat Commun. 2022 07 27; 13(1):4352. PMID: 35896539; PMCID: PMC9329333.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    34. Jones RJ, De Bie EMDD, Groves E, Zalewska KI, Swietlik EM, Treacy CM, Martin JM, Polwarth G, Li W, Guo J, Baxendale HE, Coleman S, Savinykh N, Coghlan JG, Corris PA, Howard LS, Johnson MK, Church C, Kiely DG, Lawrie A, Lordan JL, Mackenzie Ross RV, Pepke Zaba J, Wilkins MR, Wort SJ, Fiorillo E, Cucca F, Rhodes CJ, Morrell NW, McKinney EF, Wallace C, Toshner M, UK National Cohort Study of Idiopathic and Heritable PAH Consortium, Orrù V, Gräf S. Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2022 07 01; 206(1):81-93. PMID: 35316153; PMCID: PMC7613913.
      Citations: 7     Fields:    Translation:Humans
    35. Tang X, Wong M, Tena J, Zhu C, Rhodes C, Zhou Q, Vinjamuri A, Oloumi A, Boddu S, Luxardi G, Maverakis E, Lebrilla CB, Zivkovic AM. Quantitative glycoproteomics of high-density lipoproteins. RSC Adv. 2022 Jun 22; 12(29):18450-18456. PMID: 35799915; PMCID: PMC9218963.
      Citations: 1     
    36. Harbaum L, Rhodes CJ, Wharton J, Lawrie A, Karnes JH, Desai AA, Nichols WC, Boehm M, Novoyatleva T, Schermuly RT, Ghofrani HA, Toshner M, Kiely DG, Howard LS, Swietlik EM, Morrell NW, Wilkins MR, U.K. National Institute for Health Research BioResource Rare Diseases Consortium, U.K. Pulmonary Art, Humbert M, Montani D, Girerd B, Sitbon O, Gräf S, Pietzner M. Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2022 06 15; 205(12):1449-1460. PMID: 35394406; PMCID: PMC9875902.
      Citations: 18     Fields:    Translation:Humans
    37. Rhodes CJ, Wharton J, Swietlik EM, Harbaum L, Coghlan JG, Lordan J, Church C, Pepke-Zaba J, Toshner M, Wort SJ, Kiely DG, Condliffe R, Lawrie A, Howard LS, Morrell NW, Wilkins MR, Girerd B, Gräf S, Montani D, Boucly A, Sitbon O, Humbert M. Using the Plasma Proteome for Risk Stratifying Patients with Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2022 05 01; 205(9):1102-1111. PMID: 35081018; PMCID: PMC9851485.
      Citations: 21     Fields:    Translation:Humans
    38. Rhodes CJ, Sweatt AJ, Maron BA. Harnessing Big Data to Advance Treatment and Understanding of Pulmonary Hypertension. Circ Res. 2022 04 29; 130(9):1423-1444. PMID: 35482840; PMCID: PMC9070103.
      Citations: 14     Fields:    Translation:Humans
    39. Darden CM, Vasu S, Mattke J, Liu Y, Rhodes CJ, Naziruddin B, Lawrence MC. Calcineurin/NFATc2 and PI3K/AKT signaling maintains ß-cell identity and function during metabolic and inflammatory stress. iScience. 2022 Apr 15; 25(4):104125. PMID: 35402865; PMCID: PMC8983383.
      Citations: 2     
    40. Toshner M, Church C, Harbaum L, Rhodes C, Villar Moreschi SS, Liley J, Jones R, Arora A, Batai K, Desai AA, Coghlan JG, Gibbs JSR, Gor D, Harlow L, Hernandez-Sanchez J, Howard LS, Karnes J, Kiely DG, Kittles R, Knightbridge E, Lam B, Lutz KA, Nichols WC, Pauciulo MW, Pepke-Zaba J, Suntharalingam J, Trembath RC, Schwantes-An TL, Wort SJ, Wilkins MR, Gaine S, Morrell NW, Corris PA, Uniphy Clinical Trials Network, Gräf S, Humbert M, Soubrier F. Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension. Eur Respir J. 2022 03; 59(3). PMID: 34588193; PMCID: PMC8907935.
      Citations: 27     Fields:    Translation:Humans
    41. Lee DR, Rhodes C, Mitra A, Zhang Y, Maric D, Dale RK, Petros TJ. Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain. Elife. 2022 02 17; 11. PMID: 35175194; PMCID: PMC8887903.
      Citations: 11     Fields:    Translation:AnimalsCells
    42. Kariotis S, Jammeh E, Swietlik EM, Pickworth JA, Rhodes CJ, Otero P, Wharton J, Iremonger J, Dunning MJ, Pandya D, Mascarenhas TS, Errington N, Thompson AAR, Romanoski CE, Rischard F, Garcia JGN, Yuan JX, An TS, Desai AA, Coghlan G, Lordan J, Corris PA, Howard LS, Condliffe R, Kiely DG, Church C, Pepke-Zaba J, Toshner M, Wort S, Morrell NW, Wilkins MR, Lawrie A, Wang D, UK National PAH Cohort Study Consortium, Gräf S. Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood. Nat Commun. 2021 12 07; 12(1):7104. PMID: 34876579; PMCID: PMC8651638.
      Citations: 21     Fields:    Translation:HumansCells
    43. Boland BB, Laker RC, O'Brien S, Sitaula S, Sermadiras I, Nielsen JC, Barkholt P, Roostalu U, Sejthen SR, Thorbek DD, Suckow A, Burmeister N, Oldham S, Will S, Howard VG, Gill BM, Newton P, Naylor J, Hornigold DC, Austin J, Lantier L, McGuinness OP, Trevaskis JL, Grimsby JS, Rhodes CJ, Hecksher-Sørensen J. Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic ß-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries. Mol Metab. 2022 01; 55:101392. PMID: 34781035; PMCID: PMC8717237.
      Citations: 8     Fields:    Translation:AnimalsCells
    44. Romanelli SM, Lewis KT, Nishii A, Rupp AC, Li Z, Mori H, Schill RL, Learman BS, Rhodes CJ, MacDougald OA. BAd-CRISPR: Inducible gene knockout in interscapular brown adipose tissue of adult mice. J Biol Chem. 2021 12; 297(6):101402. PMID: 34774798; PMCID: PMC8661024.
      Citations: 4     Fields:    Translation:Animals
    45. Jomova K, Hudecova L, Lauro P, Barbierikova Z, Malcek M, Alwasel SH, Alhazza IM, Rhodes CJ, Valko M, Simunková M. The effect of Luteolin on DNA damage mediated by a copper catalyzed Fenton reaction. J Inorg Biochem. 2022 01; 226:111635. PMID: 34717250.
      Citations: 10     Fields:    Translation:HumansCells
    46. Barnard P, Moomaw WR, Fioramonti L, Laurance WF, Mahmoud MI, O'Sullivan J, Rapley CG, Rees WE, Rhodes CJ, Ripple WJ, Semiletov IP, Talberth J, Tucker C, Wysham D, Ziervogel G. World scientists' warnings into action, local to global. Sci Prog. 2021 10; 104(4):368504211056290. PMID: 34763547; PMCID: PMC10450599.
      Citations: 4     Fields:    Translation:Humans
    47. Wu Y, Wharton J, Walters R, Vasilaki E, Aman J, Zhao L, Wilkins MR, Rhodes CJ. The pathophysiological role of novel pulmonary arterial hypertension gene SOX17. Eur Respir J. 2021 09; 58(3). PMID: 33632800.
      Citations: 10     Fields:    Translation:Humans
    48. Mahadevan V, Mitra A, Zhang Y, Yuan X, Peltekian A, Chittajallu R, Esnault C, Maric D, Rhodes C, Pelkey KA, Dale R, Petros TJ, McBain CJ. NMDARs Drive the Expression of Neuropsychiatric Disorder Risk Genes Within GABAergic Interneuron Subtypes in the Juvenile Brain. Front Mol Neurosci. 2021; 14:712609. PMID: 34630033; PMCID: PMC8500094.
      Citations: 7     
    49. Cheng W, Ndoka E, Maung JN, Pan W, Rupp AC, Rhodes CJ, Olson DP, Myers MG. NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity. Nat Commun. 2021 08 30; 12(1):5175. PMID: 34462445; PMCID: PMC8405610.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    50. Sweatt AJ, Miyagawa K, Rhodes CJ, Taylor S, Del Rosario PA, Hsi A, Haddad F, Spiekerkoetter E, Bental-Roof M, Bland RD, Swietlik EM, Wilkins MR, Morrell NW, Nicolls MR, Rabinovitch M, Zamanian RT, Gräf S. Severe Pulmonary Arterial Hypertension Is Characterized by Increased Neutrophil Elastase and Relative Elafin Deficiency. Chest. 2021 10; 160(4):1442-1458. PMID: 34181952; PMCID: PMC8546243.
      Citations: 11     Fields:    Translation:HumansCells
    51. Errington N, Iremonger J, Pickworth JA, Kariotis S, Rhodes CJ, Rothman AM, Condliffe R, Elliot CA, Kiely DG, Howard LS, Wharton J, Thompson AAR, Morrell NW, Wilkins MR, Wang D, Lawrie A. A diagnostic miRNA signature for pulmonary arterial hypertension using a consensus machine learning approach. EBioMedicine. 2021 Jul; 69:103444. PMID: 34186489; PMCID: PMC8243351.
      Citations: 24     Fields:    Translation:HumansCells
    52. Howard LSGE, He J, Watson GMJ, Huang L, Wharton J, Luo Q, Kiely DG, Condliffe R, Pepke-Zaba J, Morrell NW, Sheares KK, Ulrich A, Quan R, Zhao Z, Jing X, An C, Liu Z, Xiong C, Robbins PA, Dawes T, de Marvao A, Rhodes CJ, Ghofrani HA, Zhao L, Huson L, Wilkins MR, Richter MJ, Gall H. Supplementation with Iron in Pulmonary Arterial Hypertension. Two Randomized Crossover Trials. Ann Am Thorac Soc. 2021 06; 18(6):981-988. PMID: 33735594; PMCID: PMC8456720.
      Citations: 18     Fields:    Translation:Humans
    53. Oldham WM, Hemnes AR, Aldred MA, Barnard J, Brittain EL, Chan SY, Cheng F, Cho MH, Desai AA, Garcia JGN, Geraci MW, Ghiassian SD, Hall KT, Horn EM, Jain M, Kelly RS, Leopold JA, Lindstrom S, Modena BD, Nichols WC, Rhodes CJ, Sun W, Sweatt AJ, Vanderpool RR, Wilkins MR, Wilmot B, Zamanian RT, Fessel JP, Aggarwal NR, Loscalzo J, Xiao L. NHLBI-CMREF Workshop Report on Pulmonary Vascular Disease Classification: JACC State-of-the-Art Review. J Am Coll Cardiol. 2021 04 27; 77(16):2040-2052. PMID: 33888254; PMCID: PMC8065203.
      Citations: 10     Fields:    Translation:Humans
    54. Le Lay JE, Du Q, Mehta MB, Bhagroo N, Hummer BT, Falloon J, Carlson G, Rosenbaum AI, Jin C, Kimko H, Tsai LF, Novick S, Cook B, Han D, Han CY, Vaisar T, Chait A, Karathanasis SK, Rhodes CJ, Hirshberg B, Damschroder MM, Hsia J, Grimsby JS. Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial. Sci Transl Med. 2021 04 21; 13(590). PMID: 33883272.
      Citations: 7     Fields:    Translation:AnimalsCTClinical Trials
    55. Swietlik EM, Ghataorhe P, Zalewska KI, Wharton J, Howard LS, Taboada D, Cannon JE, UK National Cohort Study of PAH, Morrell NW, Wilkins MR, Toshner M, Pepke-Zaba J, Rhodes CJ. Plasma metabolomics exhibit response to therapy in chronic thromboembolic pulmonary hypertension. Eur Respir J. 2021 04; 57(4). PMID: 33060150; PMCID: PMC8012591.
      Citations: 18     Fields:    Translation:Humans
    56. Ludwig MQ, Cheng W, Gordian D, Lee J, Egerod KL, Rhodes CJ, Myers MG, Pers TH, Paulsen SJ, Hansen SN, Barkholt P, Secher A, Knudsen LB, Pyke C. A genetic map of the mouse dorsal vagal complex and its role in obesity. Nat Metab. 2021 04; 3(4):530-545. PMID: 33767443.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    57. Simunkova M, Barbierikova Z, Jomova K, Hudecova L, Lauro P, Alwasel SH, Alhazza I, Rhodes CJ, Valko M. Antioxidant vs. Prooxidant Properties of the Flavonoid, Kaempferol, in the Presence of Cu(II) Ions: A ROS-Scavenging Activity, Fenton Reaction and DNA Damage Study. Int J Mol Sci. 2021 Feb 05; 22(4). PMID: 33562744; PMCID: PMC7915082.
      Citations: 28     Fields:    Translation:HumansCells
    58. Swietlik EM, Greene D, Zhu N, Megy K, Cogliano M, Rajaram S, Pandya D, Tilly T, Lutz KA, Welch CCL, Pauciulo MW, Southgate L, Martin JM, Treacy CM, Penkett CJ, Stephens JC, Bogaard HJ, Church C, Coghlan G, Coleman AW, Condliffe R, Eichstaedt CA, Gall H, Ghio S, Holden S, Howard L, Kiely DG, Kovacs G, Lordan J, Machado RD, Mackenzie Ross RV, McCabe C, Moledina S, Olschewski H, Pepke-Zaba J, Price L, Rhodes CJ, Seeger W, Suntharalingam J, Toshner MR, Vonk Noordegraaf A, Wharton J, Wild JM, Wort SJ, Lawrie A, Wilkins MR, Trembath RC, Shen Y, Chung WK, Swift AJ, Nichols WC, Morrell NW, Eyries M, Girerd B, Grünig E, Humbert M, Montani D, Soubrier F, Gräf S. Bayesian Inference Associates Rare KDR Variants with Specific Phenotypes in Pulmonary Arterial Hypertension. Circ Genom Precis Med. 2020 Dec 15. PMID: 33320693; PMCID: PMC7892262.
      Citations: 18     Fields:    
    59. Kang T, Boland BB, Jensen P, Alarcon C, Nawrocki A, Grimsby JS, Rhodes CJ, Larsen MR. Characterization of Signaling Pathways Associated with Pancreatic ß-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice. Mol Cell Proteomics. 2020 Jun; 19(6):971-993. PMID: 33451716.
      Citations:    
    60. Rhodes CJ. The cancer hypothesis of pulmonary arterial hypertension: are polyamines the new Warburg? Eur Respir J. 2020 11; 56(5). PMID: 33154079.
      Citations: 5     Fields:    Translation:Humans
    61. Ulrich A, Wharton J, Swietlik EM, Morrell NW, Wang D, Lawrie A, Wilkins MR, Prokopenko I, Rhodes CJ, Consortium OBOTNBD, Consortium UPCS, Otero-Núñez P, Gräf S. Expression Quantitative Trait Locus Mapping in Pulmonary Arterial Hypertension. Genes (Basel). 2020 10 22; 11(11). PMID: 33105808; PMCID: PMC7690609.
      Citations: 3     Fields:    Translation:HumansCells
    62. Rhodes CJ, Wharton J, Swietlik EM, Kariotis S, Harbaum L, Dunning MJ, Elinoff JM, Errington N, Thompson AAR, Iremonger J, Coghlan JG, Corris PA, Howard LS, Kiely DG, Church C, Pepke-Zaba J, Toshner M, Wort SJ, Desai AA, Nichols WC, Southgate L, Trembath RC, Prokopenko I, Morrell NW, Wang D, Lawrie A, Wilkins MR, Otero-Núñez P, Humbert M, Trégouët DA, Gräf S. Whole-Blood RNA Profiles Associated with Pulmonary Arterial Hypertension and Clinical Outcome. Am J Respir Crit Care Med. 2020 08 15; 202(4):586-594. PMID: 32352834; PMCID: PMC7427383.
      Citations: 36     Fields:    Translation:Humans
    63. Yau B, Hays L, Liang C, Laybutt DR, Thomas HE, Gunton JE, Williams L, Hawthorne WJ, Thorn P, Rhodes CJ, Kebede MA. A fluorescent timer reporter enables sorting of insulin secretory granules by age. J Biol Chem. 2020 Jul 03; 295(27):8901-8911. PMID: 33516488.
      Citations:    
    64. Sindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Bogaard HJ, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Wilkins MR, Wojciak-Stothard B, Grünig E. Author Correction: Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension. Nat Commun. 2020 06 30; 11(1):3300. PMID: 32606313; PMCID: PMC7327042.
      Citations: 4     Fields:    
    65. Boland ML, Laker RC, Mather K, Nawrocki A, Oldham S, Boland BB, Lewis H, Conway J, Naylor J, Guionaud S, Lantier L, McGuinness OP, Grimsby J, Rondinone CM, Jermutus L, Larsen MR, Trevaskis JL, Rhodes CJ, Feigh M, Veidal SS. Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis. Nat Metab. 2020 05; 2(5):413-431. PMID: 32478287; PMCID: PMC7258337.
      Citations: 85     Fields:    Translation:AnimalsCells
    66. Harbaum L, Rhodes CJ, Wharton J, Wilkins MR, Otero-Núñez P. The application of 'omics' to pulmonary arterial hypertension. Br J Pharmacol. 2021 01; 178(1):108-120. PMID: 32201940.
      Citations: 13     Fields:    Translation:Humans
    67. Yau B, Hays L, Liang C, Laybutt DR, Thomas HE, Gunton JE, Williams L, Hawthorne WJ, Thorn P, Rhodes CJ, Kebede MA. A fluorescent timer reporter enables sorting of insulin secretory granules by age. J Biol Chem. 2020 07 03; 295(27):8901-8911. PMID: 32341128; PMCID: PMC7335792.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    68. Cheng W, Ndoka E, Hutch C, Roelofs K, MacKinnon A, Khoury B, Magrisso J, Kim KS, Rhodes CJ, Olson DP, Seeley RJ, Sandoval D, Myers MG. Leptin receptor-expressing nucleus tractus solitarius neurons suppress food intake independently of GLP1 in mice. JCI Insight. 2020 04 09; 5(7). PMID: 32182221; PMCID: PMC7205255.
      Citations: 30     Fields:    Translation:AnimalsCells
    69. Kang T, Boland BB, Jensen P, Alarcon C, Nawrocki A, Grimsby JS, Rhodes CJ, Larsen MR. Characterization of Signaling Pathways Associated with Pancreatic ß-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice. Mol Cell Proteomics. 2020 06; 19(6):971-993. PMID: 32265294; PMCID: PMC7261816.
      Citations: 13     Fields:    Translation:AnimalsCells
    70. Rhodes CJ. Targeting Vessel Formation in Pulmonary Arterial Hypertension: Is the Endostatin-Id1-Thrombospondin 1 Pathway a New Hope? Am J Respir Cell Mol Biol. 2020 04; 62(4):411-412. PMID: 32049569; PMCID: PMC7110980.
      Citations: 1     Fields:    Translation:Humans
    71. Sindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Jan Bogaard H, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Wilkins MR, Wojciak-Stothard B, Grünig E. Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension. Nat Commun. 2020 03 04; 11(1):1185. PMID: 32132543; PMCID: PMC7055281.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    72. Hodgson J, Swietlik EM, Salmon RM, Hadinnapola C, Nikolic I, Wharton J, Guo J, Liley J, Haimel M, Bleda M, Southgate L, Machado RD, Martin JM, Treacy CM, Yates K, Daugherty LC, Shamardina O, Whitehorn D, Holden S, Church C, Coghlan G, Condliffe R, Corris PA, Danesino C, Gall H, Ghio S, Ghofrani HA, Gibbs JSR, Houweling AC, Howard L, Kiely DG, Kovacs G, Lawrie A, MacKenzie Ross RV, Moledina S, Olschewski A, Olschewski H, Ouwehand WH, Peacock AJ, Pepke-Zaba J, Prokopenko I, Rhodes CJ, Scelsi L, Seeger W, Suntharalingam J, Toshner MR, Trembath RC, Wort SJ, Wilkins MR, Yu PB, Li W, Upton PD, Morrell NW, Bogaard HJ, Eyries M, Girerd B, Humbert M, Montani D, Soubrier F, Vonk Noordegraaf A, Gräf S. Characterization of GDF2 Mutations and Levels of BMP9 and BMP10 in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2020 03 01; 201(5):575-585. PMID: 31661308; PMCID: PMC7047445.
      Citations: 63     Fields:    Translation:Humans
    73. Ulrich A, Wharton J, Thayer TE, Swietlik EM, Assad TR, Desai AA, Harbaum L, Morrell NW, Nichols WC, Southgate L, Trembath RC, Brittain EL, Wilkins MR, Prokopenko I, Rhodes CJ, UK PAH Cohort Study Consortium, US PAH Biobank Consortium, Gräf S, Humbert M, Soubrier F, Trégouët DA, NIHR BioResource – Rare Diseases Consortium. Mendelian randomisation analysis of red cell distribution width in pulmonary arterial hypertension. Eur Respir J. 2020 02; 55(2). PMID: 31744833; PMCID: PMC7015630.
      Citations: 22     Fields:    Translation:Humans
    74. Cheng W, Gonzalez I, Pan W, Tsang AH, Adams J, Ndoka E, Gordian D, Khoury B, Roelofs K, Evers SS, MacKinnon A, Wu S, Frikke-Schmidt H, Flak JN, Trevaskis JL, Rhodes CJ, Fukada SI, Seeley RJ, Sandoval DA, Olson DP, Blouet C, Myers MG. Calcitonin Receptor Neurons in the Mouse Nucleus Tractus Solitarius Control Energy Balance via the Non-aversive Suppression of Feeding. Cell Metab. 2020 02 04; 31(2):301-312.e5. PMID: 31955990; PMCID: PMC7104375.
      Citations: 40     Fields:    Translation:AnimalsCells
    75. Frid MG, McKeon BA, Thurman JM, Maron BA, Li M, Zhang H, Kumar S, Sullivan T, Laskowsky J, Fini MA, Hu S, Tuder RM, Gandjeva A, Wilkins MR, Rhodes CJ, Ghataorhe P, Leopold JA, Wang RS, Holers VM, Stenmark KR. Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension. Am J Respir Crit Care Med. 2020 01 15; 201(2):224-239. PMID: 31545648; PMCID: PMC6961733.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    76. Rhodes CJ. Endangered elements, critical raw materials and conflict minerals. Sci Prog. 2019 12; 102(4):304-350. PMID: 31818204; PMCID: PMC10424516.
      Citations: 11     Fields:    
    77. Rhodes CJ. Solving the plastic problem: From cradle to grave, to reincarnation. Sci Prog. 2019 09; 102(3):218-248. PMID: 31829850; PMCID: PMC10424522.
      Citations: 19     Fields:    
    78. Kang T, Boland BB, Alarcon C, Grimsby JS, Rhodes CJ, Larsen MR. Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets Following Euglycemia. J Proteome Res. 2019 09 06; 18(9):3245-3258. PMID: 31317746.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    79. Attard MI, Dawes TJW, de Marvao A, Biffi C, Shi W, Wharton J, Rhodes CJ, Ghataorhe P, Gibbs JSR, Howard LSGE, Rueckert D, Wilkins MR, O'Regan DP. Metabolic pathways associated with right ventricular adaptation to pulmonary hypertension: 3D analysis of cardiac magnetic resonance imaging. Eur Heart J Cardiovasc Imaging. 2019 Jun 01; 20(6):668-676. PMID: 30535300; PMCID: PMC6529902.
      Citations: 12     Fields:    Translation:Humans
    80. Rhodes CJ. Are insect species imperilled? Critical factors and prevailing evidence for a potential global loss of the entomofauna: A current commentary. Sci Prog. 2019 06; 102(2):181-196. PMID: 31829843; PMCID: PMC10424532.
      Citations: 7     Fields:    Translation:Animals
    81. Sofianopoulou E, Kaptoge S, Hadinnapola C, Treacy CM, Church C, Coghlan G, Gibbs JSR, Haimel M, Howard LS, Johnson M, Kiely DG, Lawrie A, Lordan J, MacKenzie Ross RV, Martin JM, Moledina S, Newnham M, Peacock AJ, Price LC, Rhodes CJ, Suntharalingam J, Swietlik EM, Toshner MR, Wharton J, Wilkins MR, Wort SJ, Pepke-Zaba J, Condliffe R, Corris PA, Di Angelantonio E, Morrell NW, Gräf S, Provencher S. Traffic exposures, air pollution and outcomes in pulmonary arterial hypertension: a UK cohort study analysis. Eur Respir J. 2019 05; 53(5). PMID: 30923185.
      Citations: 13     Fields:    Translation:HumansPHPublic Health
    82. Boland BB, Mumphrey MB, Hao Z, Townsend RL, Gill B, Oldham S, Will S, Morrison CD, Yu S, Rhodes CJ, Trevaskis JL, Berthoud HR, Münzberg H. Combined loss of GLP-1R and Y2R does not alter progression of high-fat diet-induced obesity or response to RYGB surgery in mice. Mol Metab. 2019 07; 25:64-72. PMID: 31126840; PMCID: PMC6600699.
      Citations: 21     Fields:    Translation:AnimalsCells
    83. Newnham M, South K, Bleda M, Auger WR, Bogaard H, Bunclark K, Cannon JE, Delcroix M, Hadinnapola C, Howard LS, Jenkins D, Mayer E, Ng C, Rhodes CJ, Screaton N, Sheares K, Simpson MA, Southwood M, Su L, Taboada D, Traylor M, Trembath RC, Villar SS, Wilkins MR, Wharton J, Pepke-Zaba J, Laffan M, Lane DA, Morrell NW, Toshner M, Barberà JA, Gräf S. The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension. Eur Respir J. 2019 03; 53(3). PMID: 30655285; PMCID: PMC6437602.
      Citations: 16     Fields:    Translation:Humans
    84. Waise TMZ, Rasti M, Duca FA, Zhang SY, Bauer PV, Rhodes CJ, Lam TKT. Inhibition of upper small intestinal mTOR lowers plasma glucose levels by inhibiting glucose production. Nat Commun. 2019 02 12; 10(1):714. PMID: 30755615; PMCID: PMC6372624.
      Citations: 9     Fields:    Translation:AnimalsCells
    85. Hemnes AR, Luther JM, Rhodes CJ, Burgess JP, Carlson J, Fan R, Fessel JP, Fortune N, Gerszten RE, Halliday SJ, Hekmat R, Howard L, Newman JH, Niswender KD, Pugh ME, Robbins IM, Sheng Q, Shibao CA, Shyr Y, Sumner S, Talati M, Wharton J, Wilkins MR, Ye F, Yu C, West J, Brittain EL. Human PAH is characterized by a pattern of lipid-related insulin resistance. JCI Insight. 2019 Jan 10; 4(1). PMID: 30626738; PMCID: PMC6485674.
      Citations: 53     Fields:    
    86. Rhodes CJ. Only 12 years left to readjust for the 1.5-degree climate change option - Says International Panel on Climate Change report: Current commentary. Sci Prog. 2019 03; 102(1):73-87. PMID: 31829787; PMCID: PMC10424552.
      Citations: 4     Fields:    
    87. Rhodes CJ, Batai K, Bleda M, Haimel M, Southgate L, Pauciulo MW, Hadinnapola C, Aman J, Arora A, Knight J, Hanscombe KB, Karnes JH, Kaakinen M, Gall H, Ulrich A, Harbaum L, Ferrer J, Lutz K, Swietlik EM, Ahmad F, Amouyel P, Archer SL, Argula R, Austin ED, Badesch D, Bakshi S, Barnett C, Benza R, Bhatt N, Bogaard HJ, Burger CD, Chakinala M, Church C, Coghlan JG, Condliffe R, Corris PA, Danesino C, Elliott CG, Elwing J, Fortin T, Franke A, Frantz RP, Frost A, Garcia JGN, Ghio S, Ghofrani HA, Gibbs JSR, Harley J, He H, Hill NS, Hirsch R, Houweling AC, Howard LS, Ivy D, Kiely DG, Klinger J, Kovacs G, Lahm T, Laudes M, Machado RD, MacKenzie Ross RV, Marsolo K, Martin LJ, Moledina S, Nathan SD, Newnham M, Olschewski A, Olschewski H, Oudiz RJ, Ouwehand WH, Peacock AJ, Pepke-Zaba J, Rehman Z, Robbins I, Roden DM, Rosenzweig EB, Saydain G, Scelsi L, Schilz R, Seeger W, Shaffer CM, Simms RW, Simon M, Suntharalingam J, Tang H, Tchourbanov AY, Thenappan T, Torres F, Toshner MR, Treacy CM, Vonk Noordegraaf A, Waisfisz Q, Walsworth AK, Walter RE, Wharton J, White RJ, Wilt J, Wort SJ, Yung D, Lawrie A, Prokopenko I, Kittles R, Nichols WC, Trembath RC, Desai AA, Morrell NW, Wilkins MR, UK NIHR BioResource Rare Diseases Consortium, UK PAH Cohort Study Consortium, US PAH Biobank Consortium, Germain M, Girerd B, Cebola I, Debette S, Eyries M, Montani D, Sitbon O, Humbert M, Soubrier F, Trégouët DA, Gräf S. Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis. Lancet Respir Med. 2019 03; 7(3):227-238. PMID: 30527956; PMCID: PMC6391516.
      Citations: 96     Fields:    Translation:HumansCells
    88. Harbaum L, Ghataorhe P, Wharton J, Howard LSG, Gibbs JSR, Nicholson JK, Rhodes CJ, Wilkins MR, Jiménez B. Reduced plasma levels of small HDL particles transporting fibrinolytic proteins in pulmonary arterial hypertension. Thorax. 2019 04; 74(4):380-389. PMID: 30478197; PMCID: PMC6475111.
      Citations: 20     Fields:    Translation:Humans
    89. He B, Chiba Y, Li H, de Vega S, Tanaka K, Yoshizaki K, Ishijima M, Yuasa K, Ishikawa M, Rhodes C, Sakai K, Zhang P, Fukumoto S, Zhou X, Yamada Y. Identification of the Novel Tooth-Specific Transcription Factor AmeloD. J Dent Res. 2019 02; 98(2):234-241. PMID: 30426815; PMCID: PMC6761735.
      Citations: 13     Fields:    Translation:AnimalsCells
    90. Boland BB, Brown C, Boland ML, Cann J, Sulikowski M, King W, Rondinone C, Trevaskis J, Rhodes CJ, Grimsby JS, Hansen G, Grønlund RV. Pancreatic ß-Cell Rest Replenishes Insulin Secretory Capacity and Attenuates Diabetes in an Extreme Model of Obese Type 2 Diabetes. Diabetes. 2019 01; 68(1):131-140. PMID: 30305366.
      Citations: 24     Fields:    Translation:AnimalsCells
    91. Rhodes CJ. Perovskites - some snapshots of recent developments. Sci Prog. 2018 Oct 01; 101(4):384-396. PMID: 30376446; PMCID: PMC10365158.
      Citations: 1     Fields:    
    92. Rhodes CJ. Rising sea levels - by how much, and why? Sci Prog. 2018 Oct 01; 101(4):397-410. PMID: 30376447; PMCID: PMC10365174.
      Citations: 1     Fields:    
    93. Wilkins MR, Aman J, Harbaum L, Ulrich A, Wharton J, Rhodes CJ. Recent advances in pulmonary arterial hypertension. F1000Res. 2018; 7. PMID: 30079232; PMCID: PMC6058465.
      Citations: 14     Fields:    
    94. Rhodes CJ. Plastic pollution and potential solutions. Sci Prog. 2018 Sep 01; 101(3):207-260. PMID: 30025551; PMCID: PMC10365157.
      Citations: 62     Fields:    Translation:HumansAnimalsPHPublic Health
    95. Rhodes CJ. Photonics. Sci Prog. 2018 Jun 01; 101(2):192-204. PMID: 29898805; PMCID: PMC10365181.
      Citations: 1     Fields:    
    96. Boland ML, Oldham S, Boland BB, Will S, Lapointe JM, Guionaud S, Rhodes CJ, Trevaskis JL. Nonalcoholic steatohepatitis severity is defined by a failure in compensatory antioxidant capacity in the setting of mitochondrial dysfunction. World J Gastroenterol. 2018 Apr 28; 24(16):1748-1765. PMID: 29713129; PMCID: PMC5922994.
      Citations: 24     Fields:    Translation:AnimalsCells
    97. Rhodes CJ. Pollinator decline - an ecological calamity in the making? Sci Prog. 2018 Jun 01; 101(2):121-160. PMID: 29669627; PMCID: PMC10365189.
      Citations: 23     Fields:    Translation:Animals
    98. Haimel M, Bleda M, Hadinnapola C, Southgate L, Li W, Hodgson J, Liu B, Salmon RM, Southwood M, Machado RD, Martin JM, Treacy CM, Yates K, Daugherty LC, Shamardina O, Whitehorn D, Holden S, Aldred M, Bogaard HJ, Church C, Coghlan G, Condliffe R, Corris PA, Danesino C, Gall H, Ghio S, Ghofrani HA, Gibbs JSR, Houweling AC, Howard L, Kiely DG, Kovacs G, MacKenzie Ross RV, Moledina S, Newnham M, Olschewski A, Olschewski H, Peacock AJ, Pepke-Zaba J, Prokopenko I, Rhodes CJ, Scelsi L, Seeger W, Stein DF, Suntharalingam J, Swietlik EM, Toshner MR, van Heel DA, Vonk Noordegraaf A, Waisfisz Q, Wharton J, Wort SJ, Ouwehand WH, Soranzo N, Lawrie A, Upton PD, Wilkins MR, Trembath RC, Morrell NW, Gräf S, Eyries M, Girerd B, Humbert M, Montani D, Soubrier F. Identification of rare sequence variation underlying heritable pulmonary arterial hypertension. Nat Commun. 2018 04 12; 9(1):1416. PMID: 29650961; PMCID: PMC5897357.
      Citations: 183     Fields:    Translation:HumansCells
    99. Pan W, Adams JM, Allison MB, Patterson C, Flak JN, Jones J, Strohbehn G, Trevaskis J, Rhodes CJ, Olson DP, Myers MG. Essential Role for Hypothalamic Calcitonin Receptor?Expressing Neurons in the Control of Food Intake by Leptin. Endocrinology. 2018 04 01; 159(4):1860-1872. PMID: 29522093; PMCID: PMC5888224.
      Citations: 15     Fields:    Translation:AnimalsCells
    100. Rhodes CJ. Roman concrete for durable, eco-friendly construction - applications for tidal power generation, and protection against sea level rise. Sci Prog. 2018 Mar 01; 101(1):83-91. PMID: 29467060; PMCID: PMC10365161.
      Citations: 2     Fields:    
    101. Boland BB, Brown C, Alarcon C, Demozay D, Grimsby JS, Rhodes CJ. ß-Cell Control of Insulin Production During Starvation-Refeeding in Male Rats. Endocrinology. 2018 Feb 01; 159(2):895-906. PMID: 29244064; PMCID: PMC5776497.
      Citations: 15     Fields:    Translation:AnimalsCells
    102. Kailemia MJ, Wei W, Nguyen K, Beals E, Sawrey-Kubicek L, Rhodes C, Zhu C, Sacchi R, Zivkovic AM, Lebrilla CB. Targeted Measurements of O- and N-Glycopeptides Show That Proteins in High Density Lipoprotein Particles Are Enriched with Specific Glycosylation Compared to Plasma. J Proteome Res. 2018 02 02; 17(2):834-845. PMID: 29212317; PMCID: PMC6343480.
      Citations: 13     Fields:    Translation:HumansCells
    103. Rhodes CJ. US withdrawal from the COP21 Paris Climate Change Agreement, and its possible implications. Sci Prog. 2017 Nov 17; 100(4):411-419. PMID: 29122059; PMCID: PMC10365218.
      Citations: 2     Fields:    
    104. Rhodes CJ. Photocatalysts based on graphitic carbon nitride: some prospects for artificial photosynthesis and the remediation of environmental pollution. Sci Prog. 2017 Nov 17; 100(4):400-410. PMID: 29122060; PMCID: PMC10365196.
      Citations:    Fields:    
    105. Coats BR, Schoenfelt KQ, Peris E, Cui C, Hoffman A, Zhou G, Fernandez S, Zhai L, Hall BA, Haka AS, Shah AM, Reardon CA, Brady MJ, Rhodes CJ, Maxfield FR, Becker L, Barbosa-Lorenzi VC. Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity. Cell Rep. 2017 Sep 26; 20(13):3149-3161. PMID: 28954231; PMCID: PMC5646237.
      Citations: 145     Fields:    Translation:HumansAnimalsCells
    106. Wasserfall C, Nick HS, Campbell-Thompson M, Beachy D, Haataja L, Kusmartseva I, Posgai A, Beery M, Rhodes C, Bonifacio E, Arvan P, Atkinson M. Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata. Cell Metab. 2017 Sep 05; 26(3):568-575.e3. PMID: 28877460; PMCID: PMC5679224.
      Citations: 59     Fields:    Translation:Humans
    107. Rhodes CJ. Magnetic resonance spectroscopy. Sci Prog. 2017 Sep 01; 100(3):241-292. PMID: 28779760; PMCID: PMC10365211.
      Citations: 16     Fields:    
    108. Rhodes CJ. The whispering world of plants: 'The Wood Wide Web'. Sci Prog. 2017 Sep 01; 100(3):331-337. PMID: 28779763; PMCID: PMC10365201.
      Citations: 6     Fields:    
    109. Tojais NF, Cao A, Lai YJ, Wang L, Chen PI, Alcazar MAA, de Jesus Perez VA, Hopper RK, Rhodes CJ, Bill MA, Sakai LY, Rabinovitch M. Codependence of Bone Morphogenetic Protein Receptor 2 and Transforming Growth Factor-ß in Elastic Fiber Assembly and Its Perturbation in Pulmonary Arterial Hypertension. Arterioscler Thromb Vasc Biol. 2017 08; 37(8):1559-1569. PMID: 28619995; PMCID: PMC5593082.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    110. Rhodes CJ, Wharton J, Ghataorhe P, Watson G, Howard LS, Gibbs JSR, Condliffe R, Elliot CA, Kiely DG, Gall H, Schermuly RT, Ghofrani HA, Lawrie A, Wilkins MR, Girerd B, Simonneau G, Montani D, Sitbon O, Humbert M. Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study. Lancet Respir Med. 2017 09; 5(9):717-726. PMID: 28624389; PMCID: PMC5573768.
      Citations: 71     Fields:    Translation:Humans
    111. Poprac P, Jomova K, Simunkova M, Kollar V, Rhodes CJ, Valko M. Targeting Free Radicals in Oxidative Stress-Related Human Diseases. Trends Pharmacol Sci. 2017 07; 38(7):592-607. PMID: 28551354.
      Citations: 342     Fields:    Translation:Humans
    112. Ghataorhe P, Rhodes CJ, Harbaum L, Attard M, Wharton J, Wilkins MR. Pulmonary arterial hypertension - progress in understanding the disease and prioritizing strategies for drug development. J Intern Med. 2017 08; 282(2):129-141. PMID: 28524624.
      Citations: 9     Fields:    Translation:Humans
    113. Boland BB, Rhodes CJ, Grimsby JS. The dynamic plasticity of insulin production in ß-cells. Mol Metab. 2017 09; 6(9):958-973. PMID: 28951821; PMCID: PMC5605729.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    114. Rhodes CJ. The global oil supply - prevailing situation and prognosis. Sci Prog. 2017 May 01; 100(2):231-240. PMID: 28693680; PMCID: PMC10365221.
      Citations: 2     Fields:    
    115. Trevaskis JL, Sacramento CB, Jouihan H, Ali S, Le Lay J, Oldham S, Bhagroo N, Boland BB, Cann J, Chang Y, O'Day T, Howard V, Winzell MS, Smith DM, Feigh M, Barkholt P, Thompson S, Jermutus L, Coghlan MP, Grimsby J, Rhodes CJ, Rondinone CM, Sharma A, Reers C, Schreiter K, Austen M, Andag U, Dohrmann C. Neurturin and a GLP-1 Analogue Act Synergistically to Alleviate Diabetes in Zucker Diabetic Fatty Rats. Diabetes. 2017 07; 66(7):2007-2018. PMID: 28408435.
      Citations: 7     Fields:    Translation:AnimalsCells
    116. Lee J, Luria A, Rhodes C, Raghu H, Lingampalli N, Sharpe O, Rada B, Sohn DH, Robinson WH, Sokolove J. Nicotine drives neutrophil extracellular traps formation and accelerates collagen-induced arthritis. Rheumatology (Oxford). 2017 04 01; 56(4):644-653. PMID: 28013195; PMCID: PMC5850711.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    117. Rhodes CJ. The imperative for regenerative agriculture. Sci Prog. 2017 Mar 01; 100(1):80-129. PMID: 28693674; PMCID: PMC10365184.
      Citations: 28     Fields:    
    118. Dawes TJW, de Marvao A, Shi W, Fletcher T, Watson GMJ, Wharton J, Rhodes CJ, Howard LSGE, Gibbs JSR, Rueckert D, Cook SA, Wilkins MR, O'Regan DP. Machine Learning of Three-dimensional Right Ventricular Motion Enables Outcome Prediction in Pulmonary Hypertension: A Cardiac MR Imaging Study. Radiology. 2017 05; 283(2):381-390. PMID: 28092203; PMCID: PMC5398374.
      Citations: 86     Fields:    Translation:Humans
    119. Rhodes CJ. Plasmonic nanoparticles and solar cells. Sci Prog. 2016 Dec 01; 99(4):438-449. PMID: 28742482; PMCID: PMC10365415.
      Citations:    Fields:    
    120. Rhodes CJ. Genetically modified algae produce hydrogen biofuel at five times their normal yield. Sci Prog. 2016 Dec 01; 99(4):450-451. PMID: 28742483; PMCID: PMC10365491.
      Citations:    Fields:    Translation:AnimalsCells
    121. Rhodes CJ. The 2016 Nobel Prize for Chemistry, awarded for: "The Design and Synthesis of Molecular Machines". Sci Prog. 2016 Dec 01; 99(4):452-454. PMID: 28742484; PMCID: PMC10365511.
      Citations: 1     Fields:    
    122. Rhodes CJ, Ghataorhe P, Wharton J, Rue-Albrecht KC, Hadinnapola C, Watson G, Bleda M, Haimel M, Coghlan G, Corris PA, Howard LS, Kiely DG, Peacock AJ, Pepke-Zaba J, Toshner MR, Wort SJ, Gibbs JS, Lawrie A, Morrell NW, Wilkins MR, Gräf S. Plasma Metabolomics Implicates Modified Transfer RNAs and Altered Bioenergetics in the Outcomes of Pulmonary Arterial Hypertension. Circulation. 2017 01 31; 135(5):460-475. PMID: 27881557; PMCID: PMC5287439.
      Citations: 112     Fields:    Translation:Humans
    123. Rhodes CJ. Current Commentary Recent Developments in Solar Energy Applications based on Perovskites: A Current Commentary. Sci Prog. 2016 09 01; 99(3):335-345. PMID: 28742493; PMCID: PMC10365420.
      Citations: 2     Fields:    
    124. Bowles VM, Yoon KS, Barker SC, Tran C, Rhodes C, Clark MJ. Ovicidal Efficacy of Abametapir Against Eggs of Human Head and Body Lice (Anoplura: Pediculidae). J Med Entomol. 2017 01; 54(1):167-172. PMID: 28082644; PMCID: PMC5853637.
      Citations: 3     Fields:    Translation:AnimalsCellsPHPublic Health
    125. Lythgoe MP, Rhodes CJ, Ghataorhe P, Attard M, Wharton J, Wilkins MR. Why drugs fail in clinical trials in pulmonary arterial hypertension, and strategies to succeed in the future. Pharmacol Ther. 2016 08; 164:195-203. PMID: 27133570.
      Citations: 22     Fields:    Translation:HumansAnimals
    126. Rosario W, Singh I, Wautlet A, Patterson C, Flak J, Becker TC, Ali A, Tamarina N, Philipson LH, Enquist LW, Myers MG, Rhodes CJ. The Brain-to-Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions. Diabetes. 2016 09; 65(9):2711-23. PMID: 27207534; PMCID: PMC5001176.
      Citations: 56     Fields:    Translation:Animals
    127. Hopper RK, Moonen JR, Diebold I, Cao A, Rhodes CJ, Tojais NF, Hennigs JK, Gu M, Wang L, Rabinovitch M. In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target Slug. Circulation. 2016 May 03; 133(18):1783-94. PMID: 27045138; PMCID: PMC4856565.
      Citations: 125     Fields:    Translation:HumansAnimalsCells
    128. Gellatly KJ, Krim S, Palenchar DJ, Shepherd K, Yoon KS, Rhodes CJ, Lee SH, Marshall Clark J. Expansion of the Knockdown Resistance Frequency Map for Human Head Lice (Phthiraptera: Pediculidae) in the United States Using Quantitative Sequencing. J Med Entomol. 2016 05; 53(3):653-659. PMID: 27032417; PMCID: PMC4892812.
      Citations: 17     Fields:    Translation:HumansAnimals
    129. Abrams GD, Luria A, Carr RA, Rhodes C, Robinson WH, Sokolove J. Association of synovial inflammation and inflammatory mediators with glenohumeral rotator cuff pathology. J Shoulder Elbow Surg. 2016 Jun; 25(6):989-97. PMID: 26775747.
      Citations: 25     Fields:    Translation:HumansCells
    130. Rhodes CJ. The 2015 Paris Climate Change Conference: COP21. Sci Prog. 2016; 99(Pt 1):97-104. PMID: 27120818; PMCID: PMC10365518.
      Citations: 24     Fields:    
    131. Sohn DH, Rhodes C, Onuma K, Zhao X, Sharpe O, Gazitt T, Shiao R, Fert-Bober J, Cheng D, Lahey LJ, Wong HH, Van Eyk J, Robinson WH, Sokolove J. Local Joint inflammation and histone citrullination in a murine model of the transition from preclinical autoimmunity to inflammatory arthritis. Arthritis Rheumatol. 2015 Nov; 67(11):2877-87. PMID: 26227989; PMCID: PMC4626401.
      Citations: 55     Fields:    Translation:HumansAnimals
    132. Boland BB, Ali A, Rhodes CJ, Alarcón C. Monomethylated-adenines potentiate glucose-induced insulin production and secretion via inhibition of phosphodiesterase activity in rat pancreatic islets. Islets. 2015; 7(2):e1073435. PMID: 26404841; PMCID: PMC4878263.
      Citations: 6     Fields:    Translation:AnimalsCells
    133. Valko M, Jomova K, Rhodes CJ, Kuca K, Musílek K. Redox- and non-redox-metal-induced formation of free radicals and their role in human disease. Arch Toxicol. 2016 Jan; 90(1):1-37. PMID: 26343967.
      Citations: 285     Fields:    Translation:HumansAnimalsCells
    134. Alarcon C, Boland BB, Uchizono Y, Moore PC, Peterson B, Rajan S, Rhodes OS, Noske AB, Haataja L, Arvan P, Marsh BJ, Austin J, Rhodes CJ. Pancreatic ß-Cell Adaptive Plasticity in Obesity Increases Insulin Production but Adversely Affects Secretory Function. Diabetes. 2016 Feb; 65(2):438-50. PMID: 26307586; PMCID: PMC4747460.
      Citations: 64     Fields:    Translation:AnimalsCells
    135. Rhodes CJ, Im H, Cao A, Hennigs JK, Wang L, Sa S, Chen PI, Nickel NP, Miyagawa K, Hopper RK, Tojais NF, Li CG, Gu M, Spiekerkoetter E, Xian Z, Chen R, Zhao M, Kaschwich M, Del Rosario PA, Bernstein D, Zamanian RT, Wu JC, Snyder MP, Rabinovitch M. RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2015 Aug 01; 192(3):356-66. PMID: 26030479; PMCID: PMC4584250.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    136. Laque A, Yu S, Qualls-Creekmore E, Gettys S, Schwartzenburg C, Bui K, Rhodes C, Berthoud HR, Morrison CD, Richards BK, Münzberg H. Leptin modulates nutrient reward via inhibitory galanin action on orexin neurons. Mol Metab. 2015 Oct; 4(10):706-17. PMID: 26500842; PMCID: PMC4588437.
      Citations: 35     Fields:    
    137. Rhodes CJ. Permaculture: regenerative--not merely sustainable. Sci Prog. 2015; 98(Pt 4):403-12. PMID: 26790178; PMCID: PMC10365330.
      Citations: 8     Fields:    Translation:PHPublic Health
    138. Rhodes CJ. The Diamond Light Source. Sci Prog. 2015; 98(Pt 2):192-200. PMID: 26288921; PMCID: PMC10365351.
      Citations:    Fields:    
    139. Rhodes CJ. Muon tomography: looking inside dangerous places. Sci Prog. 2015; 98(Pt 3):291-9. PMID: 26601343; PMCID: PMC10365387.
      Citations:    Fields:    
    140. Rhodes CJ, Macrae RM. "Vibrational bonding": a new type of chemical bond is discovered. Sci Prog. 2015; 98(Pt 1):12-33. PMID: 25942773; PMCID: PMC10365500.
      Citations: 2     Fields:    
    141. Rhodes CJ. Sustainable nanotechnology. Sci Prog. 2015; 98(Pt 1):63-72. PMID: 25942775; PMCID: PMC10365357.
      Citations: 1     Fields:    
    142. Rhodes CJ. Fossil fuel use is limited by climate, if not by resources, and "peak soil".. Sci Prog. 2015; 98(Pt 1):73-82. PMID: 25942776; PMCID: PMC10365461.
      Citations: 1     Fields:    
    143. Sutton AK, Pei H, Burnett KH, Myers MG, Rhodes CJ, Olson DP. Control of food intake and energy expenditure by Nos1 neurons of the paraventricular hypothalamus. J Neurosci. 2014 Nov 12; 34(46):15306-18. PMID: 25392498; PMCID: PMC4228133.
      Citations: 77     Fields:    Translation:AnimalsCells
    144. Flak JN, Patterson CM, Garfield AS, D'Agostino G, Goforth PB, Sutton AK, Malec PA, Wong JT, Germani M, Jones JC, Rajala M, Satin L, Rhodes CJ, Olson DP, Kennedy RT, Heisler LK, Myers MG. Leptin-inhibited PBN neurons enhance responses to hypoglycemia in negative energy balance. Nat Neurosci. 2014 Dec; 17(12):1744-1750. PMID: 25383904; PMCID: PMC4255234.
      Citations: 70     Fields:    Translation:AnimalsCells
    145. Wilkins MR, Aldashev AA, Wharton J, Rhodes CJ, Vandrovcova J, Kasperaviciute D, Bhosle SG, Mueller M, Geschka S, Rison S, Kojonazarov B, Morrell NW, Neidhardt I, Surmeli NB, Surmeli NB, Aitman TJ, Stasch JP, Behrends S, Marletta MA. a1-A680T variant in GUCY1A3 as a candidate conferring protection from pulmonary hypertension among Kyrgyz highlanders. Circ Cardiovasc Genet. 2014 Dec; 7(6):920-9. PMID: 25373139.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    146. Kebede MA, Oler AT, Gregg T, Balloon AJ, Johnson A, Mitok K, Rabaglia M, Schueler K, Stapleton D, Thorstenson C, Wrighton L, Floyd BJ, Richards O, Raines S, Eliceiri K, Seidah NG, Rhodes C, Keller MP, Coon JL, Audhya A, Attie AD. SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed ß cells. J Clin Invest. 2014 Oct; 124(10):4240-56. PMID: 25157818; PMCID: PMC4191024.
      Citations: 32     Fields:    Translation:AnimalsCells
    147. Iannone L, Zhao L, Dubois O, Duluc L, Rhodes CJ, Wharton J, Wilkins MR, Wojciak-Stothard B, Leiper J. miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia. Biochem J. 2014 Aug 15; 462(1):103-12. PMID: 24895913.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    148. Greene AC, Lord SJ, Tian A, Rhodes C, Kai H, Groves JT. Spatial organization of EphA2 at the cell-cell interface modulates trans-endocytosis of ephrinA1. Biophys J. 2014 May 20; 106(10):2196-205. PMID: 24853748; PMCID: PMC4052362.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    149. Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC. ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. Diabetes Care. 2014 Jun; 37(6):1751-8. PMID: 24812433; PMCID: PMC4179518.
      Citations: 221     Fields:    Translation:HumansCells
    150. Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC. ß-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. J Clin Endocrinol Metab. 2014 Jun; 99(6):1983-92. PMID: 24712577; PMCID: PMC5393482.
      Citations: 94     Fields:    Translation:HumansCells
    151. Wojciak-Stothard B, Abdul-Salam VB, Lao KH, Tsang H, Irwin DC, Lisk C, Loomis Z, Stenmark KR, Edwards JC, Yuspa SH, Howard LS, Edwards RJ, Rhodes CJ, Gibbs JS, Wharton J, Zhao L, Wilkins MR. Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension. Circulation. 2014 Apr 29; 129(17):1770-80. PMID: 24503951; PMCID: PMC4033409.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    152. Rhodes CJ. Unpaired electrons as probes of catalytic systems. Sci Prog. 2014; 97(Pt 4):303-70. PMID: 25642491; PMCID: PMC10365416.
      Citations: 1     Fields:    
    153. Rhodes CJ. Perovskites and their potential use in solar energy applications. Sci Prog. 2014; 97(Pt 3):279-87. PMID: 25551167; PMCID: PMC10365389.
      Citations: 2     Fields:    
    154. Rhodes CJ. The Fukushima Daiichi nuclear accident. Sci Prog. 2014; 97(Pt 1):72-86. PMID: 24800471; PMCID: PMC10365386.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    155. Rhodes CJ. Eating small: applications and implications for nano-technology in agriculture and the food industry. Sci Prog. 2014; 97(Pt 2):173-82. PMID: 25110799; PMCID: PMC10365522.
      Citations: 3     Fields:    Translation:Humans
    156. Rhodes CJ. Soil erosion, climate change and global food security: challenges and strategies. Sci Prog. 2014; 97(Pt 2):97-153. PMID: 25108995; PMCID: PMC10365490.
      Citations: 11     Fields:    Translation:HumansAnimalsPHPublic Health
    157. Opland D, Sutton A, Woodworth H, Brown J, Bugescu R, Garcia A, Christensen L, Rhodes C, Myers M, Leinninger G. Loss of neurotensin receptor-1 disrupts the control of the mesolimbic dopamine system by leptin and promotes hedonic feeding and obesity. Mol Metab. 2013; 2(4):423-34. PMID: 24327958; PMCID: PMC3857883.
      Citations: 61     Fields:    
    158. Diaferia GR, Jimenez-Caliani AJ, Ranjitkar P, Yang W, Hardiman G, Rhodes CJ, Crisa L, Cirulli V. ß1 integrin is a crucial regulator of pancreatic ß-cell expansion. Development. 2013 Aug; 140(16):3360-72. PMID: 23863477; PMCID: PMC3737718.
      Citations: 43     Fields:    Translation:AnimalsCells
    159. Rhodes CJ, White MF, Leahy JL, Kahn SE. Direct autocrine action of insulin on ß-cells: does it make physiological sense? Diabetes. 2013 Jul; 62(7):2157-63. PMID: 23801714; PMCID: PMC3712043.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    160. Nouvellet P, Donnelly CA, De Nardi M, Rhodes CJ, De Benedictis P, Citterio C, Obber F, Lorenzetto M, Pozza MD, Cauchemez S, Cattoli G. Rabies and canine distemper virus epidemics in the red fox population of northern Italy (2006-2010). PLoS One. 2013; 8(4):e61588. PMID: 23630599; PMCID: PMC3632604.
      Citations: 22     Fields:    Translation:AnimalsCellsPHPublic Health
    161. Rhodes CJ. Applications of bioremediation and phytoremediation. Sci Prog. 2013; 96(Pt 4):417-27. PMID: 24547671; PMCID: PMC10365495.
      Citations: 2     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    162. Rhodes CJ. Peak phosphorus - peak food? The need to close the phosphorus cycle. Sci Prog. 2013; 96(Pt 2):109-52. PMID: 23901632; PMCID: PMC10365480.
      Citations: 4     Fields:    
    163. Rhodes CJ. Current commentary: thorium-based nuclear power. Sci Prog. 2013; 96(Pt 2):200-9. PMID: 23901636; PMCID: PMC10365414.
      Citations: 1     Fields:    
    164. Rhodes CJ, Wharton J, Wilkins MR. Pulmonary hypertension: biomarkers. Handb Exp Pharmacol. 2013; 218:77-103. PMID: 24092337.
      Citations: 3     Fields:    Translation:HumansAnimals
    165. Rhodes CJ. Large Hadron Collider (LHC). Sci Prog. 2013; 96(Pt 1):95-109. PMID: 23738440; PMCID: PMC10365347.
      Citations:    Fields:    
    166. Rhodes CJ. Novel catalysts for water splitting and green chemistry applications. Sci Prog. 2013; 96(Pt 3):309-16. PMID: 24244973; PMCID: PMC10365427.
      Citations: 3     Fields:    Translation:Cells
    167. Howard LS, Watson GM, Wharton J, Rhodes CJ, Chan K, Khengar R, Robbins PA, Kiely DG, Condliffe R, Elliott CA, Pepke-Zaba J, Sheares K, Morrell NW, Davies R, Ashby D, Gibbs JS, Wilkins MR. Supplementation of iron in pulmonary hypertension: Rationale and design of a phase II clinical trial in idiopathic pulmonary arterial hypertension. Pulm Circ. 2013 Jan; 3(1):100-7. PMID: 23662181; PMCID: PMC3641712.
      Citations: 19     
    168. Rhodes CJ, Wharton J, Boon RA, Roexe T, Tsang H, Wojciak-Stothard B, Chakrabarti A, Howard LS, Gibbs JS, Lawrie A, Condliffe R, Elliot CA, Kiely DG, Huson L, Ghofrani HA, Tiede H, Schermuly R, Zeiher AM, Dimmeler S, Wilkins MR. Reduced microRNA-150 is associated with poor survival in pulmonary arterial hypertension. Am J Respir Crit Care Med. 2013 Feb 01; 187(3):294-302. PMID: 23220912.
      Citations: 84     Fields:    Translation:HumansAnimalsCells
    169. Guan H, Chow KM, Shah R, Rhodes CJ, Hersh LB. Degradation of islet amyloid polypeptide by neprilysin. Diabetologia. 2012 Nov; 55(11):2989-98. PMID: 22898766; PMCID: PMC3660010.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    170. Arvan P, Pietropaolo M, Ostrov D, Rhodes CJ. Islet autoantigens: structure, function, localization, and regulation. Cold Spring Harb Perspect Med. 2012 Aug 01; 2(8). PMID: 22908193; PMCID: PMC3405822.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    171. Gregg BE, Moore PC, Demozay D, Hall BA, Li M, Husain A, Wright AJ, Atkinson MA, Rhodes CJ. Formation of a human ß-cell population within pancreatic islets is set early in life. J Clin Endocrinol Metab. 2012 Sep; 97(9):3197-206. PMID: 22745242; PMCID: PMC3431572.
      Citations: 195     Fields:    Translation:HumansCells
    172. Manku G, Wang Y, Thuillier R, Rhodes C, Culty M. Developmental expression of the translocator protein 18 kDa (TSPO) in testicular germ cells. Curr Mol Med. 2012 May; 12(4):467-75. PMID: 22348614.
      Citations: 9     Fields:    Translation:AnimalsCells
    173. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bourquin JP, Boya P, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, Garcia-Manero G, Garcia-Marcos M, Garmyn M, Gartel AL, Gatti E, Gautel M, Gawriluk TR, Gegg ME, Geng J, Germain M, Gestwicki JE, Gewirtz DA, Ghavami S, Ghosh P, Giammarioli AM, Giatromanolaki AN, Gibson SB, Gilkerson RW, Ginger ML, Ginsberg HN, Golab J, Goligorsky MS, Golstein P, Gomez-Manzano C, Goncu E, Gonzalez CD, Gonzalez R, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. PMID: 22966490; PMCID: PMC3404883.
      Citations: 1819     Fields:    Translation:HumansAnimals
    174. Alarcon C, Verchere CB, Rhodes CJ. Translational control of glucose-induced islet amyloid polypeptide production in pancreatic islets. Endocrinology. 2012 May; 153(5):2082-7. PMID: 22408171; PMCID: PMC3339648.
      Citations: 14     Fields:    Translation:Animals
    175. Ogo T, Chowdhury HM, Zhao L, Chen CN, Rhodes C, Trembath RC, Nasim MT. BMPR-II deficiency elicits pro-proliferative and anti-apoptotic responses through the activation of TGFß-TAK1-MAPK pathways in PAH. Hum Mol Genet. 2012 Jun 01; 21(11):2548-58. PMID: 22388934.
      Citations: 38     Fields:    Translation:AnimalsCells
    176. Iversen L, Schmidt M, Rhodes C, Tu HL, Lin WC, Groves JT, Lohmüller T. Single molecule tracking on supported membranes with arrays of optical nanoantennas. Nano Lett. 2012 Mar 14; 12(3):1717-21. PMID: 22352856; PMCID: PMC3626319.
      Citations: 10     Fields:    
    177. Schley D, Tanaka RJ, Leungchavaphongse K, Shahrezaei V, Ward J, Grant C, Charleston B, Rhodes CJ. Modelling the influence of foot-and-mouth disease vaccine antigen stability and dose on the bovine immune response. PLoS One. 2012; 7(2):e30435. PMID: 22363437; PMCID: PMC3281838.
      Citations: 2     Fields:    Translation:AnimalsCellsPHPublic Health
    178. Rhodes CJ. Energy from nuclear fusion--realities, prospects and fantasies? Sci Prog. 2012; 95(Pt 1):89-98. PMID: 22574387; PMCID: PMC10365448.
      Citations: 1     Fields:    
    179. Rhodes CJ. Muonium--the second radioisotope of hydrogen: a remarkable and unique radiotracer in the chemical, materials, biological and environmental sciences. Sci Prog. 2012; 95(Pt 2):101-74. PMID: 22893978; PMCID: PMC10365539.
      Citations: 3     Fields:    
    180. Rhodes CJ. Can solar fuels avert an imminent petroleum fuel crisis? Sci Prog. 2012; 95(Pt 2):206-23. PMID: 22893981; PMCID: PMC10365447.
      Citations: 4     Fields:    
    181. Rhodes CJ. Feeding and healing the world: through regenerative agriculture and permaculture. Sci Prog. 2012; 95(Pt 4):345-446. PMID: 23469709; PMCID: PMC10365435.
      Citations: 17     Fields:    Translation:AnimalsCellsPHPublic Health
    182. Rhodes CJ. Carbon capture and storage. Sci Prog. 2012; 95(Pt 4):473-83. PMID: 23469712; PMCID: PMC10365325.
      Citations: 2     Fields:    Translation:PHPublic Health
    183. Rhodes CJ. Biochar, and its potential contribution to improving soil quality and carbon capture. Sci Prog. 2012; 95(Pt 3):330-40. PMID: 23094328; PMCID: PMC10365328.
      Citations: 3     Fields:    
    184. Owen DR, Yeo AJ, Gunn RN, Song K, Wadsworth G, Lewis A, Rhodes C, Pulford DJ, Bennacef I, Parker CA, StJean PL, Cardon LR, Mooser VE, Matthews PM, Rabiner EA, Rubio JP. An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28. J Cereb Blood Flow Metab. 2012 Jan; 32(1):1-5. PMID: 22008728; PMCID: PMC3323305.
      Citations: 391     Fields:    Translation:HumansCells
    185. Demozay D, Tsunekawa S, Briaud I, Shah R, Rhodes CJ. Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet ß-cells. Diabetes. 2011 Nov; 60(11):2892-902. PMID: 21940781; PMCID: PMC3198104.
      Citations: 37     Fields:    Translation:AnimalsCells
    186. Tsunekawa S, Demozay D, Briaud I, McCuaig J, Accili D, Stein R, Rhodes CJ. FoxO feedback control of basal IRS-2 expression in pancreatic ß-cells is distinct from that in hepatocytes. Diabetes. 2011 Nov; 60(11):2883-91. PMID: 21933986; PMCID: PMC3198101.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    187. Syed I, Kyathanahalli CN, Jayaram B, Govind S, Rhodes CJ, Kowluru RA, Kowluru A. Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet. Diabetes. 2011 Nov; 60(11):2843-52. PMID: 21911753; PMCID: PMC3198065.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    188. Leinninger GM, Opland DM, Jo YH, Faouzi M, Christensen L, Cappellucci LA, Rhodes CJ, Gnegy ME, Becker JB, Pothos EN, Seasholtz AF, Thompson RC, Myers MG. Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance. Cell Metab. 2011 Sep 07; 14(3):313-23. PMID: 21907138; PMCID: PMC3183584.
      Citations: 184     Fields:    Translation:AnimalsCells
    189. Wang S, Ota S, Guo B, Ryu J, Rhodes C, Xiong Y, Kalim S, Zeng L, Chen Y, Teitell MA, Zhang X. Subcellular resolution mapping of endogenous cytokine secretion by nano-plasmonic-resonator sensor array. Nano Lett. 2011 Aug 10; 11(8):3431-4. PMID: 21780816; PMCID: PMC3163910.
      Citations: 8     Fields:    Translation:HumansCells
    190. Rhodes CJ, Howard LS, Busbridge M, Ashby D, Kondili E, Gibbs JS, Wharton J, Wilkins MR. Iron deficiency and raised hepcidin in idiopathic pulmonary arterial hypertension: clinical prevalence, outcomes, and mechanistic insights. J Am Coll Cardiol. 2011 Jul 12; 58(3):300-9. PMID: 21737024.
      Citations: 115     Fields:    Translation:HumansCells
    191. Rhodes CJ, Wharton J, Howard LS, Gibbs JS, Wilkins MR. Red cell distribution width outperforms other potential circulating biomarkers in predicting survival in idiopathic pulmonary arterial hypertension. Heart. 2011 Jul; 97(13):1054-60. PMID: 21558476.
      Citations: 72     Fields:    Translation:HumansCells
    192. Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, Pietropaolo M, Arvan PR, Von Herrath M, Markel DS, Rhodes CJ. How does type 1 diabetes develop?: the notion of homicide or ß-cell suicide revisited. Diabetes. 2011 May; 60(5):1370-9. PMID: 21525508; PMCID: PMC3292309.
      Citations: 124     Fields:    Translation:HumansAnimalsCells
    193. Tanabe K, Liu Y, Hasan SD, Martinez SC, Welling CM, Bernal-Mizrachi E, Tanizawa Y, Rhodes CJ, Zmuda E, Hai T, Abumrad NA, Permutt MA, Cras-Méneur C. Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3ß independent of JNK activation. PLoS One. 2011 Apr 26; 6(4):e18146. PMID: 21541314; PMCID: PMC3082528.
      Citations: 21     Fields:    Translation:AnimalsCells
    194. Rhodes CJ, Wharton J, Howard L, Gibbs JS, Vonk-Noordegraaf A, Wilkins MR. Iron deficiency in pulmonary arterial hypertension: a potential therapeutic target. Eur Respir J. 2011 Dec; 38(6):1453-60. PMID: 21478213.
      Citations: 52     Fields:    Translation:HumansAnimals
    195. Jomova K, Jenisova Z, Feszterova M, Baros S, Liska J, Hudecova D, Rhodes CJ, Valko M. Arsenic: toxicity, oxidative stress and human disease. J Appl Toxicol. 2011 Mar; 31(2):95-107. PMID: 21321970.
      Citations: 337     Fields:    Translation:HumansAnimals
    196. Zhang Y, Kerman IA, Laque A, Nguyen P, Faouzi M, Louis GW, Jones JC, Rhodes C, Münzberg H. Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits. J Neurosci. 2011 Feb 02; 31(5):1873-84. PMID: 21289197; PMCID: PMC3069639.
      Citations: 139     Fields:    Translation:AnimalsCells
    197. Syed I, Kyathanahalli CN, Rhodes CJ, Kowluru A, Jayaram B. Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 ß-cells and rat islets. Biochem Pharmacol. 2011 Apr 15; 81(8):1016-27. PMID: 21276423; PMCID: PMC3073812.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    198. Rhodes CJ. The price of oil. Sci Prog. 2011; 94(Pt 1):1-9. PMID: 21548527; PMCID: PMC10365463.
      Citations: 3     Fields:    
    199. Rhodes CJ. Electron spin resonance. Part one: a diagnostic method in the biomedical sciences. Sci Prog. 2011; 94(Pt 1):16-96. PMID: 21548528; PMCID: PMC10365421.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    200. Rhodes CJ. Shortage of resources for renewable energy and food production. Sci Prog. 2011; 94(Pt 3):323-34. PMID: 22026151; PMCID: PMC10365380.
      Citations: 6     Fields:    Translation:PHPublic Health
    201. Rhodes CJ. Ionic liquids and green futures. Sci Prog. 2011; 94(Pt 2):211-9. PMID: 21805912; PMCID: PMC10365531.
      Citations: 3     Fields:    
    202. Rhodes CJ. Electron spin resonance. Part two: a diagnostic method in the environmental sciences. Sci Prog. 2011; 94(Pt 4):339-413. PMID: 22308901; PMCID: PMC10365504.
      Citations: 7     Fields:    
    203. Rhodes CJ. Current commentary: Can free radicals be good for you? Sci Prog. 2011; 94(Pt 4):451-62. PMID: 22308904; PMCID: PMC10365444.
      Citations: 3     Fields:    Translation:Humans
    204. Leen JL, Izzo A, Upadhyay C, Rowland KJ, Gu S, Heximer SP, Rhodes CJ, Storm DR, Lund PK, Brubaker PL, Dubé PE. Mechanism of action of glucagon-like peptide-2 to increase IGF-I mRNA in intestinal subepithelial fibroblasts. Endocrinology. 2011 Feb; 152(2):436-46. PMID: 21159855; PMCID: PMC3384785.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    205. Rhodes CJ, Demetrius L. Evolutionary entropy determines invasion success in emergent epidemics. PLoS One. 2010 Sep 23; 5(9):e12951. PMID: 20886082; PMCID: PMC2944876.
      Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
    206. Louis GW, Leinninger GM, Rhodes CJ, Myers MG. Direct innervation and modulation of orexin neurons by lateral hypothalamic LepRb neurons. J Neurosci. 2010 Aug 25; 30(34):11278-87. PMID: 20739548; PMCID: PMC2930259.
      Citations: 57     Fields:    Translation:AnimalsCells
    207. Zarrouki B, Hagman DK, Latour MG, Semache M, Roskens V, Moore PC, Prentki M, Rhodes CJ, Jetton TL, Poitout V, Fontés G. Glucolipotoxicity age-dependently impairs beta cell function in rats despite a marked increase in beta cell mass. Diabetologia. 2010 Nov; 53(11):2369-79. PMID: 20628728; PMCID: PMC2947580.
      Citations: 61     Fields:    Translation:AnimalsCells
    208. Wilkins MR, Ali O, Bradlow W, Wharton J, Taegtmeyer A, Rhodes CJ, Ghofrani HA, Howard L, Nihoyannopoulos P, Mohiaddin RH, Gibbs JS, Simvastatin Pulmonary Hypertension Trial (SiPHT) Study Group. Simvastatin as a treatment for pulmonary hypertension trial. Am J Respir Crit Care Med. 2010 May 15; 181(10):1106-13. PMID: 20460548; PMCID: PMC2874452.
      Citations: 47     Fields:    Translation:Humans
    209. Leng S, Zhang W, Zheng Y, Liberman Z, Rhodes CJ, Eldar-Finkelman H, Sun XJ. Glycogen synthase kinase 3 beta mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1. J Endocrinol. 2010 Aug; 206(2):171-81. PMID: 20466847; PMCID: PMC3072280.
      Citations: 42     Fields:    Translation:AnimalsCells
    210. Rhodes CJ, Martin AP. The influence of viral infection on a plankton ecosystem undergoing nutrient enrichment. J Theor Biol. 2010 Aug 07; 265(3):225-37. PMID: 20433852.
      Citations: 3     Fields:    
    211. Leshan RL, Opland DM, Louis GW, Leinninger GM, Patterson CM, Rhodes CJ, Myers MG, Münzberg H. Ventral tegmental area leptin receptor neurons specifically project to and regulate cocaine- and amphetamine-regulated transcript neurons of the extended central amygdala. J Neurosci. 2010 Apr 21; 30(16):5713-23. PMID: 20410123; PMCID: PMC2864009.
      Citations: 77     Fields:    Translation:AnimalsCells
    212. Zheng H, Patterson LM, Rhodes CJ, Louis GW, Skibicka KP, Grill HJ, Myers MG, Berthoud HR. A potential role for hypothalamomedullary POMC projections in leptin-induced suppression of food intake. Am J Physiol Regul Integr Comp Physiol. 2010 Mar; 298(3):R720-8. PMID: 20071607; PMCID: PMC2838656.
      Citations: 41     Fields:    Translation:AnimalsCells
    213. Kowluru A, Veluthakal R, Rhodes CJ, Kamath V, Syed I, Koch BJ. Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells. Diabetes. 2010 Apr; 59(4):967-77. PMID: 20071600; PMCID: PMC2844844.
      Citations: 33     Fields:    Translation:AnimalsCells
    214. Rhodes CJ. Properties and applications of zeolites. Sci Prog. 2010; 93(Pt 3):223-84. PMID: 21047018; PMCID: PMC10365492.
      Citations: 23     Fields:    Translation:CellsPHPublic Health
    215. Rhodes CJ. Solar energy: principles and possibilities. Sci Prog. 2010; 93(Pt 1):37-112. PMID: 20222355; PMCID: PMC10365508.
      Citations: 15     Fields:    
    216. Meares GP, Hughes KJ, Jaimes KF, Salvatori AS, Rhodes CJ, Corbett JA. AMP-activated protein kinase attenuates nitric oxide-induced beta-cell death. J Biol Chem. 2010 Jan 29; 285(5):3191-200. PMID: 19933272; PMCID: PMC2823419.
      Citations: 21     Fields:    Translation:AnimalsCells
    217. Leinninger GM, Jo YH, Leshan RL, Louis GW, Yang H, Barrera JG, Wilson H, Opland DM, Faouzi MA, Gong Y, Jones JC, Rhodes CJ, Chua S, Diano S, Horvath TL, Seeley RJ, Becker JB, Myers MG, Münzberg H. Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding. Cell Metab. 2009 Aug; 10(2):89-98. PMID: 19656487; PMCID: PMC2723060.
      Citations: 221     Fields:    Translation:AnimalsCells
    218. Bruun C, Heding PE, Rhodes CJ, Mandrup-Poulsen T, Billestrup N, Rønn SG, Frobøse H. Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells. Mol Cell Endocrinol. 2009 Nov 13; 311(1-2):32-8. PMID: 19643162.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    219. German J, Kim F, Schwartz GJ, Havel PJ, Rhodes CJ, Schwartz MW, Morton GJ. Hypothalamic leptin signaling regulates hepatic insulin sensitivity via a neurocircuit involving the vagus nerve. Endocrinology. 2009 Oct; 150(10):4502-11. PMID: 19574396; PMCID: PMC2754686.
      Citations: 89     Fields:    Translation:AnimalsCells
    220. Semache M, Hagman DK, Tremblay C, Shah R, Rhodes CJ, Rutter J, Poitout V, Fontés G. Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells. Diabetes. 2009 Sep; 58(9):2048-58. PMID: 19502418; PMCID: PMC2731539.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    221. Leshan RL, Louis GW, Jo YH, Rhodes CJ, Myers MG, Münzberg H. Direct innervation of GnRH neurons by metabolic- and sexual odorant-sensing leptin receptor neurons in the hypothalamic ventral premammillary nucleus. J Neurosci. 2009 Mar 11; 29(10):3138-47. PMID: 19279251; PMCID: PMC2675106.
      Citations: 89     Fields:    Translation:AnimalsCells
    222. Rhodes CJ, Hollingsworth TD. Variational data assimilation with epidemic models. J Theor Biol. 2009 Jun 21; 258(4):591-602. PMID: 19268475.
      Citations: 22     Fields:    Translation:HumansAnimalsPHPublic Health
    223. Rhodes CJ. Oil from algae; salvation from peak oil? Sci Prog. 2009; 92(Pt 1):39-90. PMID: 19544699; PMCID: PMC10361130.
      Citations: 10     Fields:    Translation:Animals
    224. Rhodes CJ, Anderson RM. Contact rate calculation for a basic epidemic model. Math Biosci. 2008 Nov; 216(1):56-62. PMID: 18783724.
      Citations: 11     Fields:    Translation:HumansAnimalsPHPublic Health
    225. Rhodes CJ, Davidson A, Gibbs JS, Wharton J, Wilkins MR. Therapeutic targets in pulmonary arterial hypertension. Pharmacol Ther. 2009 Jan; 121(1):69-88. PMID: 19010350.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    226. Lim GE, Huang GJ, Flora N, LeRoith D, Rhodes CJ, Brubaker PL. Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell. Endocrinology. 2009 Feb; 150(2):580-91. PMID: 18818290; PMCID: PMC5393261.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    227. Garske T, Rhodes CJ. The effect of superspreading on epidemic outbreak size distributions. J Theor Biol. 2008 Jul 21; 253(2):228-37. PMID: 18423673.
      Citations: 33     Fields:    Translation:HumansPHPublic Health
    228. Rhodes CJ. The oil question: nature and prognosis. Sci Prog. 2008; 91(Pt 4):317-75. PMID: 19192735; PMCID: PMC10367496.
      Citations: 12     Fields:    
    229. Uchizono Y, Wicksteed BL, Marsh BJ, Rhodes CJ, Alarcón C. The balance between proinsulin biosynthesis and insulin secretion: where can imbalance lead? Diabetes Obes Metab. 2007 Nov; 9 Suppl 2:56-66. PMID: 17919179.
      Citations: 45     Fields:    Translation:HumansCells
    230. Liu M, Hodish I, Rhodes CJ, Arvan P. Proinsulin maturation, misfolding, and proteotoxicity. Proc Natl Acad Sci U S A. 2007 Oct 02; 104(40):15841-6. PMID: 17898179; PMCID: PMC2000385.
      Citations: 96     Fields:    Translation:HumansCells
    231. Bjork A, Starmer WT, Higginson DM, Rhodes CJ, Pitnick S. Complex interactions with females and rival males limit the evolution of sperm offence and defence. Proc Biol Sci. 2007 Jul 22; 274(1619):1779-88. PMID: 17507332; PMCID: PMC2493577.
      Citations: 24     Fields:    Translation:AnimalsCells
    232. Marsh BJ, Soden C, Wicksteed BL, Yaekura K, Costin AJ, Morgan GP, Rhodes CJ, Alarcón C. Regulated autophagy controls hormone content in secretory-deficient pancreatic endocrine beta-cells. Mol Endocrinol. 2007 Sep; 21(9):2255-69. PMID: 17579214.
      Citations: 83     Fields:    Translation:AnimalsCells
    233. Wicksteed B, Uchizono Y, Alarcon C, McCuaig JF, Shalev A, Rhodes CJ. A cis-element in the 5' untranslated region of the preproinsulin mRNA (ppIGE) is required for glucose regulation of proinsulin translation. Cell Metab. 2007 Mar; 5(3):221-7. PMID: 17339029.
      Citations: 30     Fields:    Translation:AnimalsCells
    234. Churchill D, Beevers GD, Meher S, Rhodes C. Diuretics for preventing pre-eclampsia. Cochrane Database Syst Rev. 2007 Jan 24; (1):CD004451. PMID: 17253507; PMCID: PMC8826571.
      Citations: 19     Fields:    Translation:Humans
    235. Moss LG, Rhodes CJ. Beta-cell regeneration: epithelial mesenchymal transition pre-EMTpted by lineage tracing? Diabetes. 2007 Jan; 56(1):281-2. PMID: 17192494.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    236. Alarcon C, Wicksteed B, Rhodes CJ. Exendin 4 controls insulin production in rat islet beta cells predominantly by potentiation of glucose-stimulated proinsulin biosynthesis at the translational level. Diabetologia. 2006 Dec; 49(12):2920-9. PMID: 17053883.
      Citations: 35     Fields:    Translation:AnimalsCells
    237. Kaido T, Yebra M, Cirulli V, Rhodes C, Diaferia G, Montgomery AM. Impact of defined matrix interactions on insulin production by cultured human beta-cells: effect on insulin content, secretion, and gene transcription. Diabetes. 2006 Oct; 55(10):2723-9. PMID: 17003336.
      Citations: 55     Fields:    Translation:HumansCells
    238. Joseph JW, Jensen MV, Ilkayeva O, Palmieri F, Rhodes CJ, Newgard CB, Alárcon C. The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion. J Biol Chem. 2006 Nov 24; 281(47):35624-32. PMID: 17001083.
      Citations: 81     Fields:    Translation:AnimalsCells
    239. Marzban L, Rhodes CJ, Steiner DF, Haataja L, Halban PA, Verchere CB. Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death. Diabetes. 2006 Aug; 55(8):2192-201. PMID: 16873681.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    240. Wang L, Rhodes CJ, Lawrence JC. Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1. J Biol Chem. 2006 Aug 25; 281(34):24293-303. PMID: 16798736.
      Citations: 66     Fields:    Translation:AnimalsCells
    241. Sadagurski M, Yakar S, Weingarten G, Holzenberger M, Rhodes CJ, Breitkreutz D, Leroith D, Wertheimer E. Insulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiation. Mol Cell Biol. 2006 Apr; 26(7):2675-87. PMID: 16537911; PMCID: PMC1430337.
      Citations: 49     Fields:    Translation:AnimalsCells
    242. Lingohr MK, Briaud I, Dickson LM, McCuaig JF, Wicksteed BL, Rhodes CJ, Alárcon C. Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet beta-cells. J Biol Chem. 2006 Jun 09; 281(23):15884-92. PMID: 16574657.
      Citations: 37     Fields:    Translation:AnimalsCells
    243. Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact. 2006 Mar 10; 160(1):1-40. PMID: 16430879.
      Citations: 1547     Fields:    Translation:HumansAnimalsCells
    244. Gelling RW, Morton GJ, Morrison CD, Niswender KD, Myers MG, Rhodes CJ, Schwartz MW. Insulin action in the brain contributes to glucose lowering during insulin treatment of diabetes. Cell Metab. 2006 Jan; 3(1):67-73. PMID: 16399506.
      Citations: 79     Fields:    Translation:Animals
    245. Morton GJ, Gelling RW, Niswender KD, Morrison CD, Rhodes CJ, Schwartz MW. Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons. Cell Metab. 2005 Dec; 2(6):411-20. PMID: 16330326.
      Citations: 146     Fields:    Translation:AnimalsCells
    246. Schuit F, Halban P, Rhodes C. 10th EASD/JDRF Oxford Workshop. What is a beta-cell and can we improve it? Diabetologia. 2005 Nov; 48(11):R93-101. PMID: 16372395.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    247. Atkinson MA, Rhodes CJ. Pancreatic regeneration in type 1 diabetes: dreams on a deserted islet? Diabetologia. 2005 Nov; 48(11):2200-2. PMID: 16193285.
      Citations: 6     Fields:    Translation:Humans
    248. Tamarina NA, Kuznetsov A, Rhodes CJ, Bindokas VP, Philipson LH. Inositol (1,4,5)-trisphosphate dynamics and intracellular calcium oscillations in pancreatic beta-cells. Diabetes. 2005 Nov; 54(11):3073-81. PMID: 16249428.
      Citations: 27     Fields:    Translation:AnimalsCells
    249. Jerdeva GV, Wu K, Yarber FA, Rhodes CJ, Kalman D, Schechter JE, Hamm-Alvarez SF. Actin and non-muscle myosin II facilitate apical exocytosis of tear proteins in rabbit lacrimal acinar epithelial cells. J Cell Sci. 2005 Oct 15; 118(Pt 20):4797-812. PMID: 16219687; PMCID: PMC1482462.
      Citations: 50     Fields:    Translation:AnimalsCells
    250. Jerdeva GV, Yarber FA, Trousdale MD, Rhodes CJ, Okamoto CT, Dartt DA, Hamm-Alvarez SF. Dominant-negative PKC-epsilon impairs apical actin remodeling in parallel with inhibition of carbachol-stimulated secretion in rabbit lacrimal acini. Am J Physiol Cell Physiol. 2005 Oct; 289(4):C1052-68. PMID: 15930141; PMCID: PMC1414898.
      Citations: 13     Fields:    Translation:Animals
    251. Li L, El-Kholy W, Rhodes CJ, Brubaker PL. Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: role of protein kinase B. Diabetologia. 2005 Jul; 48(7):1339-49. PMID: 15902400.
      Citations: 70     Fields:    Translation:AnimalsCells
    252. Hays LB, Wicksteed B, Wang Y, McCuaig JF, Philipson LH, Edwardson JM, Rhodes CJ. Intragranular targeting of syncollin, but not a syncollinGFP chimera, inhibits regulated insulin exocytosis in pancreatic beta-cells. J Endocrinol. 2005 Apr; 185(1):57-67. PMID: 15817827.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    253. Morton GJ, Blevins JE, Williams DL, Niswender KD, Gelling RW, Rhodes CJ, Baskin DG, Schwartz MW. Leptin action in the forebrain regulates the hindbrain response to satiety signals. J Clin Invest. 2005 Mar; 115(3):703-10. PMID: 15711637; PMCID: PMC548313.
      Citations: 96     Fields:    Translation:HumansAnimalsCells
    254. Sadagurski M, Weingarten G, Rhodes CJ, White MF, Wertheimer E. Insulin receptor substrate 2 plays diverse cell-specific roles in the regulation of glucose transport. J Biol Chem. 2005 Apr 15; 280(15):14536-44. PMID: 15705592.
      Citations: 12     Fields:    Translation:AnimalsCells
    255. Rhodes CJ. Type 2 diabetes-a matter of beta-cell life and death? Science. 2005 Jan 21; 307(5708):380-4. PMID: 15662003.
      Citations: 343     Fields:    Translation:HumansAnimalsCells
    256. Lin Y, Berg AH, Iyengar P, Lam TK, Giacca A, Combs TP, Rajala MW, Du X, Rollman B, Li W, Hawkins M, Barzilai N, Rhodes CJ, Fantus IG, Brownlee M, Scherer PE. The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species. J Biol Chem. 2005 Feb 11; 280(6):4617-26. PMID: 15536073.
      Citations: 171     Fields:    Translation:AnimalsCells
    257. Briaud I, Dickson LM, Lingohr MK, McCuaig JF, Lawrence JC, Rhodes CJ. Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTOR)-induced negative feedback down-regulates protein kinase B-mediated signaling pathway in beta-cells. J Biol Chem. 2005 Jan 21; 280(3):2282-93. PMID: 15537654.
      Citations: 67     Fields:    Translation:AnimalsCells
    258. Valko M, Izakovic M, Mazur M, Rhodes CJ, Telser J. Role of oxygen radicals in DNA damage and cancer incidence. Mol Cell Biochem. 2004 Nov; 266(1-2):37-56. PMID: 15646026.
      Citations: 391     Fields:    Translation:HumansAnimalsCells
    259. Michael DJ, Geng X, Cawley NX, Loh YP, Rhodes CJ, Drain P, Chow RH. Fluorescent cargo proteins in pancreatic beta-cells: design determines secretion kinetics at exocytosis. Biophys J. 2004 Dec; 87(6):L03-5. PMID: 15516519; PMCID: PMC1304941.
      Citations: 29     Fields:    Translation:AnimalsCells
    260. Finlay D, Patel S, Dickson LM, Shpiro N, Marquez R, Rhodes CJ, Sutherland C. Glycogen synthase kinase-3 regulates IGFBP-1 gene transcription through the thymine-rich insulin response element. BMC Mol Biol. 2004 Sep 06; 5:15. PMID: 15350195; PMCID: PMC517930.
      Citations: 24     Fields:    Translation:AnimalsCells
    261. Dickson LM, Rhodes CJ. Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt? Am J Physiol Endocrinol Metab. 2004 Aug; 287(2):E192-8. PMID: 15271644.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    262. 40th EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004. Diabetologia. 2004 Aug; 47(Suppl 1):A1-A464. PMID: 27770180; PMCID: PMC7096100.
      Citations: 20     Fields:    
    263. Hays LB, Rhodes CJ, Edwardson JM, Wäsle B. Syncollin inhibits regulated corticotropin secretion from AtT-20 cells through a reduction in the secretory vesicle population. Biochem J. 2004 Jun 15; 380(Pt 3):897-905. PMID: 15040787; PMCID: PMC1224234.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    264. Ma L, Bindokas VP, Kuznetsov A, Rhodes C, Hays L, Edwardson JM, Ueda K, Steiner DF, Philipson LH. Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion. Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9266-71. PMID: 15197259; PMCID: PMC438965.
      Citations: 44     Fields:    Translation:AnimalsCells
    265. Rhodes CJ, Tran TT, Morris H. A determination of antioxidant efficiencies using ESR and computational methods. Spectrochim Acta A Mol Biomol Spectrosc. 2004 May; 60(6):1401-10. PMID: 15134741.
      Citations: 4     Fields:    
    266. El-Assaad W, Rhodes CJ, Rosenberg L, Joly E, Prentki M, Buteau J. Glucagon-like peptide-1 prevents beta cell glucolipotoxicity. Diabetologia. 2004 May; 47(5):806-15. PMID: 15095038.
      Citations: 106     Fields:    Translation:HumansCells
    267. Nolan C, Alarcon C, Moore P, Barbeau A, Delghingaro-Augusto V, Przybykowski E, Morin J, Massie B, Ruderman N, Rhodes C, Poitout V, Prentki M, Roduit R, Massé F. A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli. Diabetes. 2004 Apr; 53(4):1007-19. PMID: 15047616.
      Citations: 63     Fields:    Translation:AnimalsCells
    268. Wang Q, Li L, Xu E, Wong V, Rhodes C, Brubaker PL. Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells. Diabetologia. 2004 Mar; 47(3):478-487. PMID: 14762654.
      Citations: 62     Fields:    Translation:AnimalsCells
    269. Marzban L, Trigo-Gonzalez G, Zhu X, Rhodes CJ, Halban PA, Steiner DF, Verchere CB. Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide. Diabetes. 2004 Jan; 53(1):141-8. PMID: 14693708.
      Citations: 39     Fields:    Translation:AnimalsCells
    270. Lingohr MK, Dickson LM, Wrede CE, Briaud I, McCuaig JF, Myers MG, Rhodes CJ. Decreasing IRS-2 expression in pancreatic beta-cells (INS-1) promotes apoptosis, which can be compensated for by introduction of IRS-4 expression. Mol Cell Endocrinol. 2003 Nov 14; 209(1-2):17-31. PMID: 14604813.
      Citations: 22     Fields:    Translation:AnimalsCells
    271. Wicksteed B, Alarcon C, Briaud I, Lingohr MK, Rhodes CJ. Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin. J Biol Chem. 2003 Oct 24; 278(43):42080-90. PMID: 12928442.
      Citations: 53     Fields:    Translation:AnimalsCells
    272. Song SH, Rhodes CJ, Veldhuis JD, Butler PC. Diazoxide attenuates glucose-induced defects in first-phase insulin release and pulsatile insulin secretion in human islets. Endocrinology. 2003 Aug; 144(8):3399-405. PMID: 12865318.
      Citations: 20     Fields:    Translation:HumansCells
    273. Li X, Tupper JC, Bannerman DD, Winn RK, Rhodes CJ, Harlan JM. Phosphoinositide 3 kinase mediates Toll-like receptor 4-induced activation of NF-kappa B in endothelial cells. Infect Immun. 2003 Aug; 71(8):4414-20. PMID: 12874320; PMCID: PMC166052.
      Citations: 47     Fields:    Translation:HumansCells
    274. Lingohr MK, Dickson LM, Wrede CE, McCuaig JF, Myers MG, Rhodes CJ. IRS-3 inhibits IRS-2-mediated signaling in pancreatic beta-cells. Mol Cell Endocrinol. 2003 Jun 30; 204(1-2):85-99. PMID: 12850284.
      Citations: 9     Fields:    Translation:AnimalsCells
    275. Wrede CE, Dickson LM, Lingohr MK, Briaud I, Rhodes CJ. Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta-cells (INS-1). J Mol Endocrinol. 2003 Jun; 30(3):271-86. PMID: 12790799.
      Citations: 19     Fields:    Translation:HumansCells
    276. Kelpe CL, Moore PC, Parazzoli SD, Wicksteed B, Rhodes CJ, Poitout V. Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis. J Biol Chem. 2003 Aug 08; 278(32):30015-21. PMID: 12771145.
      Citations: 102     Fields:    Translation:AnimalsCells
    277. Morton GJ, Niswender KD, Rhodes CJ, Myers MG, Blevins JE, Baskin DG, Schwartz MW. Arcuate nucleus-specific leptin receptor gene therapy attenuates the obesity phenotype of Koletsky (fa(k)/fa(k)) rats. Endocrinology. 2003 May; 144(5):2016-24. PMID: 12697710.
      Citations: 74     Fields:    Translation:AnimalsCells
    278. Briaud I, Lingohr MK, Dickson LM, Wrede CE, Rhodes CJ. Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells. Diabetes. 2003 Apr; 52(4):974-83. PMID: 12663469.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    279. Friedrichsen BN, Richter HE, Hansen JA, Rhodes CJ, Nielsen JH, Billestrup N, Møldrup A. Signal transducer and activator of transcription 5 activation is sufficient to drive transcriptional induction of cyclin D2 gene and proliferation of rat pancreatic beta-cells. Mol Endocrinol. 2003 May; 17(5):945-58. PMID: 12586844.
      Citations: 37     Fields:    Translation:AnimalsCells
    280. Yaekura K, Julyan R, Wicksteed BL, Hays LB, Alarcon C, Sommers S, Poitout V, Baskin DG, Wang Y, Philipson LH, Rhodes CJ. Insulin secretory deficiency and glucose intolerance in Rab3A null mice. J Biol Chem. 2003 Mar 14; 278(11):9715-21. PMID: 12510060.
      Citations: 59     Fields:    Translation:Animals
    281. Wrede CE, Dickson LM, Lingohr MK, Briaud I, Rhodes CJ. Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1). J Biol Chem. 2002 Dec 20; 277(51):49676-84. PMID: 12393870.
      Citations: 94     Fields:    Translation:AnimalsCells
    282. Alarcon C, Wicksteed B, Prentki M, Corkey BE, Rhodes CJ. Succinate is a preferential metabolic stimulus-coupling signal for glucose-induced proinsulin biosynthesis translation. Diabetes. 2002 Aug; 51(8):2496-504. PMID: 12145163.
      Citations: 36     Fields:    Translation:AnimalsCells
    283. Lingohr MK, Buettner R, Rhodes CJ. Pancreatic beta-cell growth and survival--a role in obesity-linked type 2 diabetes? Trends Mol Med. 2002 Aug; 8(8):375-84. PMID: 12127723.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    284. Spinks TJ, Camici PG, Bloomfield PM, Rhodes CG, Law MP, Baker CS, Rimoldi O, Schäfers KP. Absolute quantification of myocardial blood flow with H(2)(15)O and 3-dimensional PET: an experimental validation. J Nucl Med. 2002 Aug; 43(8):1031-40. PMID: 12163628.
      Citations: 23     Fields:    Translation:Animals
    285. El-Sayed M, Ginski M, Rhodes C, Ghandehari H. Transepithelial transport of poly(amidoamine) dendrimers across Caco-2 cell monolayers. J Control Release. 2002 Jun 17; 81(3):355-65. PMID: 12044574.
      Citations: 54     Fields:    Translation:HumansCells
    286. Rhodes CJ, White MF. Molecular insights into insulin action and secretion. Eur J Clin Invest. 2002 Jun; 32 Suppl 3:3-13. PMID: 12028370.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    287. Rhodes CJ, Reid ID, Zimmermann U. Muonium addition to DMPO and PBN sorbed in silica-gel. Chem Commun (Camb). 2002 May 21; (10):1092-3. PMID: 12122680.
      Citations: 3     Fields:    
    288. Donelan MJ, Morfini G, Julyan R, Sommers S, Hays L, Kajio H, Briaud I, Easom RA, Molkentin JD, Brady ST, Rhodes CJ. Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis. J Biol Chem. 2002 Jul 05; 277(27):24232-42. PMID: 11978799.
      Citations: 41     Fields:    Translation:AnimalsCells
    289. Lingohr MK, Dickson LM, McCuaig JF, Hugl SR, Twardzik DR, Rhodes CJ. Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation. Diabetes. 2002 Apr; 51(4):966-76. PMID: 11916914.
      Citations: 50     Fields:    Translation:AnimalsCells
    290. Rhodes CJ, Reid ID. A radiolabelling study of radicals derived from benzene, toluene and benzaldehyde sorbed in model environmental carbon. Spectrochim Acta A Mol Biomol Spectrosc. 2002 Apr; 58(6):1209-17. PMID: 11993469.
      Citations: 2     Fields:    
    291. Niswender KD, Morton GJ, Stearns WH, Rhodes CJ, Myers MG, Schwartz MW. Intracellular signalling. Key enzyme in leptin-induced anorexia. Nature. 2001 Oct 25; 413(6858):794-5. PMID: 11677594.
      Citations: 213     Fields:    Translation:AnimalsCells
    292. Halban PA, Kahn SE, Rhodes CJ. Gene and cell-replacement therapy in the treatment of type 1 diabetes: how high must the standards be set? Diabetes. 2001 Oct; 50(10):2181-91. PMID: 11574396.
      Citations: 24     Fields:    Translation:HumansAnimals
    293. Buteau J, Foisy S, Rhodes CJ, Carpenter L, Biden TJ, Prentki M. Protein kinase Czeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation. Diabetes. 2001 Oct; 50(10):2237-43. PMID: 11574404.
      Citations: 85     Fields:    Translation:AnimalsCells
    294. Kajio H, Olszewski S, Rosner PJ, Donelan MJ, Geoghegan KF, Rhodes CJ. A low-affinity Ca2+-dependent association of calmodulin with the Rab3A effector domain inversely correlates with insulin exocytosis. Diabetes. 2001 Sep; 50(9):2029-39. PMID: 11522668.
      Citations: 9     Fields:    Translation:AnimalsCells
    295. Skelly RH, Wicksteed B, Antinozzi PA, Rhodes CJ. Glycerol-stimulated proinsulin biosynthesis in isolated pancreatic rat islets via adenoviral-induced expression of glycerol kinase is mediated via mitochondrial metabolism. Diabetes. 2001 Aug; 50(8):1791-8. PMID: 11473040.
      Citations: 9     Fields:    Translation:AnimalsCells
    296. Wicksteed B, Herbert TP, Alarcon C, Lingohr MK, Moss LG, Rhodes CJ. Cooperativity between the preproinsulin mRNA untranslated regions is necessary for glucose-stimulated translation. J Biol Chem. 2001 Jun 22; 276(25):22553-8. PMID: 11297542.
      Citations: 28     Fields:    Translation:AnimalsCells
    297. Dickson LM, Lingohr MK, McCuaig J, Hugl SR, Snow L, Kahn BB, Myers MG, Rhodes CJ. Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1). J Biol Chem. 2001 Jun 15; 276(24):21110-20. PMID: 11274216.
      Citations: 35     Fields:    Translation:AnimalsCells
    298. Tsai H, Hardisty RE, Rhodes C, Kiernan AE, Roby P, Tymowska-Lalanne Z, Mburu P, Rastan S, Hunter AJ, Brown SD, Steel KP. The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti. Hum Mol Genet. 2001 Mar 01; 10(5):507-12. PMID: 11181574.
      Citations: 42     Fields:    Translation:AnimalsCells
    299. Cousin SP, Wrede CE, Kajio H, Myers MG, Rhodes CJ, Hügl SR. Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1. Endocrinology. 2001 Jan; 142(1):229-40. PMID: 11145586.
      Citations: 115     Fields:    Translation:AnimalsCells
    300. Cousin SP, Hu Gl SR, Wrede CE, Kajio H, Myers MG, Rhodes CJ. Free Fatty Acid-Induced Inhibition of Glucose and Insulin-Like Growth Factor I-Induced Deoxyribonucleic Acid Synthesis in the Pancreatic ß-Cell Line INS-1* * This work was supported by grants from the NIH (GK-55267), the Juvenile Diabetes Foundation International, the German Research Society, and BetaGene, Inc. Endocrinology. 2001 Jan 01; 142(1):229-240. PMID: 28201086.
      Citations:    
    301. Rhodes CJ, Dintinger TC, Moynihan HA, Reid ID. "Spin-labelling" with the second hydrogen radioisotope: radicals formed from squalene by muonium addition. Free Radic Res. 2000 Jul; 33(1):75-9. PMID: 10826923.
      Citations: 1     Fields:    
    302. Park JY, Takahara N, Gabriele A, Chou E, Naruse K, Suzuma K, Yamauchi T, Ha SW, Meier M, Rhodes CJ, King GL. Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation. Diabetes. 2000 Jul; 49(7):1239-48. PMID: 10909984.
      Citations: 58     Fields:    Translation:AnimalsCells
    303. Rhodes CJ. IGF-I and GH post-receptor signaling mechanisms for pancreatic beta-cell replication. J Mol Endocrinol. 2000 Jun; 24(3):303-11. PMID: 10828823.
      Citations: 22     Fields:    Translation:HumansCells
    304. Deeney JT, Gromada J, Olsen HL, Rhodes CJ, Prentki M, Berggren PO, Corkey BE, Høy M. Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells). J Biol Chem. 2000 Mar 31; 275(13):9363-8. PMID: 10734079.
      Citations: 40     Fields:    Translation:AnimalsCells
    305. Brown H, Meister B, Deeney J, Corkey BE, Yang SN, Larsson O, Rhodes CJ, Seino S, Berggren PO, Fried G. Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis. Diabetes. 2000 Mar; 49(3):383-91. PMID: 10868959.
      Citations: 16     Fields:    Translation:AnimalsCells
    306. Buettner R, Newgard CB, Rhodes CJ, O'Doherty RM. Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia. Am J Physiol Endocrinol Metab. 2000 Mar; 278(3):E563-9. PMID: 10710512.
      Citations: 26     Fields:    Translation:Animals
    307. Kuboki K, Jiang ZY, Takahara N, Ha SW, Igarashi M, Yamauchi T, Feener EP, Herbert TP, Rhodes CJ, King GL. Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo : a specific vascular action of insulin. Circulation. 2000 Feb 15; 101(6):676-81. PMID: 10673261.
      Citations: 156     Fields:    Translation:AnimalsCells
    308. Zhu J, Tseng YH, Kantor JD, Rhodes CJ, Zetter BR, Moyers JS, Kahn CR. Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation. Proc Natl Acad Sci U S A. 1999 Dec 21; 96(26):14911-8. PMID: 10611312; PMCID: PMC24747.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    309. Cousin SP, Myers MG, White MF, Reifel-Miller A, Rhodes CJ, Hügl SR. Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling. Biochem J. 1999 Dec 15; 344 Pt 3:649-58. PMID: 10585851; PMCID: PMC1220686.
      Citations: 21     Fields:    Translation:AnimalsCells
    310. Igarashi M, Wakasaki H, Takahara N, Ishii H, Jiang ZY, Yamauchi T, Kuboki K, Meier M, Rhodes CJ, King GL. Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways. J Clin Invest. 1999 Jan; 103(2):185-95. PMID: 9916130; PMCID: PMC407875.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    311. Norgren S, Berggren PO, Fredholm BB, Larsson O, Rhodes CJ, Herbert TP, Luthman H, Köhler M. Changes in cytoplasmic ATP concentration parallels changes in ATP-regulated K+-channel activity in insulin-secreting cells. FEBS Lett. 1998 Dec 11; 441(1):97-102. PMID: 9877173.
      Citations: 6     Fields:    Translation:AnimalsCells
    312. Brown H, Larsson O, Yang SN, Leibiger B, Leibiger I, Fried G, Moede T, Deeney JT, Brown GR, Jacobsson G, Rhodes CJ, Braun JE, Scheller RH, Corkey BE, Berggren PO, Meister B, Bränström R. Cysteine string protein (CSP) is an insulin secretory granule-associated protein regulating beta-cell exocytosis. EMBO J. 1998 Sep 01; 17(17):5048-58. PMID: 9724640; PMCID: PMC1170832.
      Citations: 25     Fields:    Translation:AnimalsCells
    313. White MF, Rhodes CJ, Hügl SR. Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells. J Biol Chem. 1998 Jul 10; 273(28):17771-9. PMID: 9651378.
      Citations: 64     Fields:    Translation:Cells
    314. Leahy JL, Chen C, Rhodes CJ. How is the insulin content regulated in nondiabetic hyperinsulinaemic, insulin resistant states? Study of spontaneously hypertensive rats. Diabetologia. 1998 Jul; 41(7):855-9. PMID: 9686930.
      Citations:    Fields:    Translation:AnimalsCells
    315. Schuppin GT, Pons S, Aiello LP, King GL, White M, Rhodes CJ, Hügl S. A specific increased expression of insulin receptor substrate 2 in pancreatic beta-cell lines is involved in mediating serum-stimulated beta-cell growth. Diabetes. 1998 Jul; 47(7):1074-85. PMID: 9648831.
      Citations: 14     Fields:    Translation:AnimalsCells
    316. Skelly RH, Bollheimer LC, Wicksteed BL, Corkey BE, Rhodes CJ. A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties. Biochem J. 1998 Apr 15; 331 ( Pt 2):553-61. PMID: 9531497; PMCID: PMC1219388.
      Citations: 13     Fields:    Translation:AnimalsCells
    317. Bollheimer LC, Skelly RH, Chester MW, McGarry JD, Rhodes CJ. Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation. J Clin Invest. 1998 Mar 01; 101(5):1094-101. PMID: 9486980; PMCID: PMC508661.
      Citations: 57     Fields:    Translation:AnimalsCells
    318. Rhodes CJ, Butler AR, Anderson RM. Epidemiology of communicable disease in small populations. J Mol Med (Berl). 1998 Feb; 76(2):111-6. PMID: 9500676.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    319. Rhodes CJ, Jensen HJ, Anderson RM. On the critical behaviour of simple epidemics. Proc Biol Sci. 1997 Nov 22; 264(1388):1639-46. PMID: 9404027; PMCID: PMC1688722.
      Citations: 12     Fields:    Translation:HumansPHPublic Health
    320. Rhodes CJ, Hinds CS, Morris H, Reid ID. Muon spectroscopy applied to biological systems: a study of thiyl radicals, RS. Free Radic Res. 1997 Oct; 27(4):347-52. PMID: 9416462.
      Citations: 1     Fields:    Translation:HumansAnimals
    321. Rhodes CJ, Anderson RM. Epidemic thresholds and vaccination in a lattice model of disease spread. Theor Popul Biol. 1997 Oct; 52(2):101-18. PMID: 9356327.
      Citations: 15     Fields:    Translation:HumansAnimalsPHPublic Health
    322. Lynch E, Sheerin A, Claxson AW, Atherton MD, Rhodes CJ, Silwood CJ, Naughton DP, Grootveld M. Multicomponent spectroscopic investigations of salivary antioxidant consumption by an oral rinse preparation containing the stable free radical species chlorine dioxide (ClO2.). Free Radic Res. 1997 Mar; 26(3):209-34. PMID: 9161844.
      Citations: 10     Fields:    Translation:HumansCells
    323. Cheatham B, Volchuk A, Kahn CR, Wang L, Rhodes CJ, Klip A. Insulin-stimulated translocation of GLUT4 glucose transporters requires SNARE-complex proteins. Proc Natl Acad Sci U S A. 1996 Dec 24; 93(26):15169-73. PMID: 8986782; PMCID: PMC26375.
      Citations: 54     Fields:    Translation:AnimalsCells
    324. Lipes MA, Cooper EM, Skelly R, Rhodes CJ, Boschetti E, Weir GC, Davalli AM. Insulin-secreting non-islet cells are resistant to autoimmune destruction. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8595-600. PMID: 8710916; PMCID: PMC38718.
      Citations: 8     Fields:    Translation:AnimalsCells
    325. Nakata K, Miyamoto S, Bernier S, Tanaka M, Utani A, Krebsbach P, Rhodes C, Yamada Y. The c-propeptide of type II procollagen binds to the enhancer region of the type II procollagen gene and regulates its transcription. Ann N Y Acad Sci. 1996 Jun 08; 785:307-8. PMID: 8702163.
      Citations: 1     Fields:    Translation:AnimalsCells
    326. Berggren PO, Bertorello AM, Bokvist K, Chibalin A, Deeney JT, Flatt PR, Gromada J, Larsson O, Rhodes CJ, Rorsman P, Eliasson L, Renström E, Ammälä C, Gäbel J, Lindström P. PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic beta cells. Science. 1996 Feb 09; 271(5250):813-5. PMID: 8628999.
      Citations: 40     Fields:    Translation:AnimalsCells
    327. Schuppin GT, Rhodes CJ. Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing beta TC3 cells. Biochem J. 1996 Jan 01; 313 ( Pt 1):259-68. PMID: 8546693; PMCID: PMC1216892.
      Citations: 12     Fields:    Translation:AnimalsCells
    328. Skelly RH, Schuppin GT, Ishihara H, Oka Y, Rhodes CJ. Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line. Diabetes. 1996 Jan; 45(1):37-43. PMID: 8522057.
      Citations: 19     Fields:    Translation:AnimalsCells
    329. Kowluru A, Seavey SE, Rhodes CJ, Metz SA. A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent beta cells. Biochem J. 1996 Jan 01; 313 ( Pt 1):97-107. PMID: 8546716; PMCID: PMC1216915.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    330. Rhodes C, Yamada Y. Characterization of a glucocorticoid responsive element and identification of an AT-rich element that regulate the link protein gene. Nucleic Acids Res. 1995 Jun 25; 23(12):2305-13. PMID: 7610060; PMCID: PMC307022.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    331. Leahy JL, Schuppin GT, Rhodes CJ, Alarcón C. Increased secretory demand rather than a defect in the proinsulin conversion mechanism causes hyperproinsulinemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus. J Clin Invest. 1995 Mar; 95(3):1032-9. PMID: 7883951; PMCID: PMC441437.
      Citations: 26     Fields:    Translation:AnimalsCells
    332. Malizia A, Forse G, Haida A, Gunn R, Melichar J, Poole K, Bateman D, Fahy D, Schnorr L, Brown D, Rhodes C, Nutt DJ, Jones T. A new human (psycho)pharmacology tool: the multiple organs coincidences counter (MOCC). J Psychopharmacol. 1995 Jan; 9(4):294-306. PMID: 22298393.
      Citations: 2     Fields:    
    333. Olszewski S, Deeney JT, Schuppin GT, Williams KP, Corkey BE, Rhodes CJ. Rab3A effector domain peptides induce insulin exocytosis via a specific interaction with a cytosolic protein doublet. J Biol Chem. 1994 Nov 11; 269(45):27987-91. PMID: 7961732.
      Citations: 10     Fields:    Translation:AnimalsCells
    334. Cheatham B, Lincoln B, Kahn CR, Siddle K, Rhodes CJ, Alarcón C. A Kex2-related endopeptidase activity present in rat liver specifically processes the insulin proreceptor. Biochem J. 1994 Jul 01; 301 ( Pt 1):257-65. PMID: 8037679; PMCID: PMC1137170.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    335. Rhodes CJ, Alarcón C. What beta-cell defect could lead to hyperproinsulinemia in NIDDM? Some clues from recent advances made in understanding the proinsulin-processing mechanism. Diabetes. 1994 Apr; 43(4):511-7. PMID: 8138054.
      Citations: 43     Fields:    Translation:HumansCells
    336. Rehemtulla A, Barr PJ, Rhodes CJ, Kaufman RJ. PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE. Biochemistry. 1993 Nov 02; 32(43):11586-90. PMID: 8218226.
      Citations: 12     Fields:    Translation:AnimalsCells
    337. Lincoln B, Rhodes CJ, Alarcón C. The biosynthesis of the subtilisin-related proprotein convertase PC3, but no that of the PC2 convertase, is regulated by glucose in parallel to proinsulin biosynthesis in rat pancreatic islets. J Biol Chem. 1993 Feb 25; 268(6):4276-80. PMID: 8440711.
      Citations: 54     Fields:    Translation:Animals
    338. Rhodes CJ, Thorne BA, Lincoln B, Nielsen E, Hutton JC, Thomas G. Processing of proopiomelanocortin by insulin secretory granule proinsulin processing endopeptidases. J Biol Chem. 1993 Feb 25; 268(6):4267-75. PMID: 8382698; PMCID: PMC4295213.
      Citations: 7     Fields:    Translation:AnimalsCells
    339. Rhodes CJ, Lincoln B, Shoelson SE. Preferential cleavage of des-31,32-proinsulin over intact proinsulin by the insulin secretory granule type II endopeptidase. Implication of a favored route for prohormone processing. J Biol Chem. 1992 Nov 15; 267(32):22719-27. PMID: 1429623.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    340. Hecht JT, Blanton SH, Wang Y, Daiger SP, Horton WA, Rhodes C, Yamada Y, Francomano CA. Exclusion of human proteoglycan link protein (CRTL1) and type II collagen (COL2A1) genes in pseudoachondroplasia. Am J Med Genet. 1992 Nov 01; 44(4):420-4. PMID: 1442879.
      Citations: 4     Fields:    Translation:Humans
    341. Clawson GA, Norbeck LL, Hatem CL, Rhodes C, Amiri P, McKerrow JH, Patierno SR, Fiskum G. Ca(2+)-regulated serine protease associated with the nuclear scaffold. Cell Growth Differ. 1992 Nov; 3(11):827-38. PMID: 1467310.
      Citations: 6     Fields:    Translation:AnimalsCells
    342. Wentworth BM, Rhodes C, Schnetzler B, Gross DJ, Halban PA, Villa-Komaroff L. The ratio of mouse insulin I:insulin II does not reflect that of the corresponding preproinsulin mRNAs. Mol Cell Endocrinol. 1992 Aug; 86(3):177-86. PMID: 1511787.
      Citations: 6     Fields:    Translation:AnimalsCells
    343. Lindberg I, Lincoln B, Rhodes CJ. Fluorometric assay of a calcium-dependent, paired-basic processing endopeptidase present in insulinoma granules. Biochem Biophys Res Commun. 1992 Feb 28; 183(1):1-7. PMID: 1543479.
      Citations: 5     Fields:    Translation:AnimalsCells
    344. Hecht JT, Wang Y, Rhodes C, Yamada Y. TaqI and HaeIII RFLP polymorphisms in human proteoglycan link gene (CRTL1). Nucleic Acids Res. 1991 Dec 11; 19(23):6666. PMID: 1684430; PMCID: PMC329277.
      Citations: 1     Fields:    Translation:HumansCells
    345. Hecht JT, Wang Y, Rhodes C, Yamada Y. GT repeat polymorphism in the human proteoglycan link gene (CRTL1) promoter region. Nucleic Acids Res. 1991 Dec 11; 19(23):6666. PMID: 1754418; PMCID: PMC329278.
      Citations: 3     Fields:    Translation:HumansCells
    346. Hutton JC, Rhodes CJ. The enzymology of proinsulin conversion. Cell Biophys. 1991 Oct-Dec; 19(1-3):57-62. PMID: 1726888.
      Citations:    Fields:    Translation:HumansAnimals
    347. Rhodes C, Savagner P, Line S, Sasaki M, Chirigos M, Doege K, Yamada Y. Characterization of the promoter for the rat and human link protein gene. Nucleic Acids Res. 1991 Apr 25; 19(8):1933-9. PMID: 2030970; PMCID: PMC328126.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    348. Hutton JC, Bailyes EM, Rhodes CJ, Rutherford NG, Arden SD, Guest PC. Biosynthesis and storage of insulin. Biochem Soc Trans. 1990 Feb; 18(1):122-4. PMID: 2185075.
      Citations: 2     Fields:    Translation:HumansAnimals
    349. Rosenberg D, Rhodes C, Ferre C, Handler A. Ensuring quality in a computerized database system: a perinatal network. Indian J Pediatr. 1990 Jan-Feb; 57(1):63-71. PMID: 2361710.
      Citations:    Fields:    
    350. Guest PC, Pipeleers D, Rossier J, Rhodes CJ, Hutton JC. Co-secretion of carboxypeptidase H and insulin from isolated rat islets of Langerhans. Biochem J. 1989 Dec 01; 264(2):503-8. PMID: 2481446; PMCID: PMC1133608.
      Citations: 5     Fields:    Translation:Animals
    351. Docherty K, Rhodes CJ, Taylor NA, Shennan KI, Hutton JC. Proinsulin endopeptidase substrate specificities defined by site-directed mutagenesis of proinsulin. J Biol Chem. 1989 Nov 05; 264(31):18335-9. PMID: 2478543.
      Citations: 14     Fields:    Translation:AnimalsCells
    352. Larkin SW, Clarke JG, Keogh BE, Araujo L, Rhodes C, Davies GJ, Taylor KM, Maseri A. Intracoronary endothelin induces myocardial ischemia by small vessel constriction in the dog. Am J Cardiol. 1989 Oct 15; 64(14):956-8. PMID: 2679033.
      Citations: 7     Fields:    Translation:Animals
    353. Rhodes CJ, Brennan SO, Hutton JC. Proalbumin to albumin conversion by a proinsulin processing endopeptidase of insulin secretory granules. J Biol Chem. 1989 Aug 25; 264(24):14240-5. PMID: 2503514.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    354. Rhodes CJ, Zumbrunn A, Bailyes EM, Shaw E, Hutton JC. The inhibition of proinsulin-processing endopeptidase activities by active-site-directed peptides. Biochem J. 1989 Feb 15; 258(1):305-8. PMID: 2649090; PMCID: PMC1138356.
      Citations: 11     Fields:    Translation:AnimalsCells
    355. Segui-Real B, Rhodes C, Yamada Y. The human genome contains a pseudogene for the Mr=32,000 laminin binding protein. Nucleic Acids Res. 1989 Feb 11; 17(3):1257. PMID: 2522184; PMCID: PMC331757.
      Citations: 4     Fields:    Translation:HumansCells
    356. Guest PC, Rhodes CJ, Hutton JC. Regulation of the biosynthesis of insulin-secretory-granule proteins. Co-ordinate translational control is exerted on some, but not all, granule matrix constituents. Biochem J. 1989 Jan 15; 257(2):431-7. PMID: 2649074; PMCID: PMC1135598.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    357. Hutton JC, Guest PC, Rhodes CJ, Fricker LD, Grimaldi KA, Siddle K, Davidson W, Bailyes EM. [Biogenesis of the insulin secretion granule]. Journ Annu Diabetol Hotel Dieu. 1989; 13-28. PMID: 2548031.
      Citations:    Fields:    Translation:HumansAnimalsCells
    358. Davidson HW, Rhodes CJ, Hutton JC. Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic beta cell via two distinct site-specific endopeptidases. Nature. 1988 May 05; 333(6168):93-6. PMID: 3283564.
      Citations: 117     Fields:    Translation:AnimalsCells
    359. Rhodes C, Doege K, Sasaki M, Yamada Y. Alternative splicing generates two different mRNA species for rat link protein. J Biol Chem. 1988 May 05; 263(13):6063-7. PMID: 2452158.
      Citations: 11     Fields:    Translation:AnimalsCells
    360. Rhodes CJ, Halban PA. The intracellular handling of insulin-related peptides in isolated pancreatic islets. Evidence for differential rates of degradation of insulin and C-peptide. Biochem J. 1988 Apr 01; 251(1):23-30. PMID: 3291861; PMCID: PMC1148959.
      Citations: 5     Fields:    Translation:AnimalsCells
    361. Rhodes CJ, Lucas CA, Mutkoski RL, Orci L, Halban PA. Stimulation by ATP of proinsulin to insulin conversion in isolated rat pancreatic islet secretory granules. Association with the ATP-dependent proton pump. J Biol Chem. 1987 Aug 05; 262(22):10712-7. PMID: 2440873.
      Citations: 30     Fields:    Translation:AnimalsCells
    362. Rhodes CJ, Halban PA. Newly synthesized proinsulin/insulin and stored insulin are released from pancreatic B cells predominantly via a regulated, rather than a constitutive, pathway. J Cell Biol. 1987 Jul; 105(1):145-53. PMID: 3301864; PMCID: PMC2114904.
      Citations: 60     Fields:    Translation:AnimalsCells
    363. Rhodes CJ, Lucas CA, Halban PA. Glucose stimulates the biosynthesis of rat I and II insulin to an equal extent in isolated pancreatic islets. FEBS Lett. 1987 May 04; 215(1):179-82. PMID: 3552733.
      Citations: 8     Fields:    Translation:AnimalsCells
    364. Halban PA, Rhodes CJ, Shoelson SE. High-performance liquid chromatography (HPLC): a rapid, flexible and sensitive method for separating islet proinsulin and insulin. Diabetologia. 1986 Dec; 29(12):893-6. PMID: 3552815.
      Citations: 10     Fields:    Translation:Animals
    365. Rhodes CJ, Taylor KW. Effect of interferon and double-stranded RNA on B-cell function in mouse islets of Langerhans. Biochem J. 1985 May 15; 228(1):87-94. PMID: 2408612; PMCID: PMC1144956.
      Citations: 5     Fields:    Translation:AnimalsCells
    366. Rhodes CJ, Campbell IL, Szopa TM, Biden TJ, Reynolds PD, Fernando ON, Taylor KW. Effects of glucose and D-3-hydroxybutyrate on human pancreatic islet cell function. Clin Sci (Lond). 1985 May; 68(5):567-72. PMID: 3884239.
      Citations: 2     Fields:    Translation:HumansCells
    367. Rhodes CJ, Taylor KW. 2-5A-dependent endoribonuclease activity and effects of A2'p5'A2'p5'A (2-5A core) in mouse pancreatic islets. FEBS Lett. 1985 Jan 21; 180(1):69-73. PMID: 3881279.
      Citations: 1     Fields:    Translation:Animals
    368. Rhodes CJ, Taylor KW. Effect of human lymphoblastoid interferon on insulin synthesis and secretion in isolated human pancreatic islets. Diabetologia. 1984 Dec; 27(6):601-3. PMID: 6397387.
      Citations: 6     Fields:    Translation:Humans
    369. Hellqvist LN, Rhodes CJ, Taylor KW. Long-term biochemical changes in the islets of Langerhans in mice following infection with encephalomyocarditis virus. Diabetologia. 1984 May; 26(5):370-4. PMID: 6329865.
      Citations: 4     Fields:    Translation:AnimalsCells
    370. Rhodes C, Dodgson KS, Olavesen AH, Högberg B. Unsuitability of indoxyl acetate as a substrate for the assay of testicular hyaluronidase. Biochem J. 1971 May; 122(4):575-82. PMID: 5166330; PMCID: PMC1176816.
      Citations: 3     Fields:    Translation:Animals
    371. Rhodes C, Olavesen AH, Dodgson KS. Hydrolysis of indoxyl acetate by bovine testicular hyaluronidase preparations. Biochem J. 1970 Jun; 118(2):18P-19P. PMID: 5530186; PMCID: PMC1179151.
      Citations:    Fields:    Translation:Animals
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