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Increased expression of PS1 is sufficient to elevate the level and activity of ?-secretase in vivo.
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Increased expression of PS1 is sufficient to elevate the level and activity of ?-secretase in vivo.
Increased expression of PS1 is sufficient to elevate the level and activity of ?-secretase in vivo. PLoS One. 2011; 6(11):e28179.
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Alzheimer Disease
Amyloid beta-Peptides
Amyloid Precursor Protein Secretases
Animals
Brain
Humans
Mice
Mutation
Neurons
Presenilin-1
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Sangram Sisodia