 Bupropion
"Bupropion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A unicyclic, aminoketone antidepressant. The mechanism of its therapeutic actions is not well understood, but it does appear to block dopamine uptake. The hydrochloride is available as an aid to smoking cessation treatment.
| Descriptor ID |
D016642
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| MeSH Number(s) |
D02.522.818.110
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| Concept/Terms |
Bupropion- Bupropion
- Amfebutamone
- (+-)-1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
Wellbutrin- Wellbutrin
- GlaxoSmithKline Brand 2 of Bupropion Hydrochloride
- Glaxo Wellcome Brand 2 of Bupropion Hydrochloride
Zyban (Anti-Smoking)- Zyban (Anti-Smoking)
- GlaxoSmithKline Brand 1 of Bupropion Hydrochloride
- Glaxo Wellcome Brand 1 of Bupropion Hydrochloride
Zyntabac- Zyntabac
- Glaxo Wellcome Brand 3 of Bupropion Hydrochloride
Quomen- Quomen
- Esteve Brand of Bupropion Hydrochloride
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Below are MeSH descriptors whose meaning is more general than "Bupropion".
Below are MeSH descriptors whose meaning is more specific than "Bupropion".
This graph shows the total number of publications written about "Bupropion" by people in this website by year, and whether "Bupropion" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 | | 2004 | 2 | 0 | 2 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2013 | 0 | 2 | 2 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Bupropion" by people in Profiles.
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Chhabra N, DesLauriers C, Wahl M, Bryant SM. Management of severe bupropion poisoning with intravenous lipid emulsion. Clin Toxicol (Phila). 2018 Jan; 56(1):51-54.
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Nissen SE, Wolski KE, Prcela L, Wadden T, Buse JB, Bakris G, Perez A, Smith SR. Effect of Naltrexone-Bupropion on Major Adverse Cardiovascular Events in Overweight and Obese Patients With Cardiovascular Risk Factors: A Randomized Clinical Trial. JAMA. 2016 Mar 08; 315(10):990-1004.
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Gibbons RD, Mann JJ. Varenicline, smoking cessation, and neuropsychiatric adverse events. Am J Psychiatry. 2013 Dec; 170(12):1460-7.
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Kornfield R, Watson S, Higashi AS, Conti RM, Dusetzina SB, Garfield CF, Dorsey ER, Huskamp HA, Alexander GC. Effects of FDA advisories on the pharmacologic treatment of ADHD, 2004-2008. Psychiatr Serv. 2013 Apr 01; 64(4):339-46.
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Dwoskin LP, Pivavarchyk M, Joyce BM, Neugebauer NM, Zheng G, Zhang Z, Bardo MT, Crooks PA. Targeting reward-relevant nicotinic receptors in the discovery of novel pharmacotherapeutic agents to treat tobacco dependence. Nebr Symp Motiv. 2009; 55:31-63.
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Acheson A, de Wit H. Bupropion improves attention but does not affect impulsive behavior in healthy young adults. Exp Clin Psychopharmacol. 2008 Apr; 16(2):113-23.
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Mansvelder HD, Fagen ZM, Chang B, Mitchum R, McGehee DS. Bupropion inhibits the cellular effects of nicotine in the ventral tegmental area. Biochem Pharmacol. 2007 Oct 15; 74(8):1283-91.
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Wilens TE, Hammerness PG, Biederman J, Kwon A, Spencer TJ, Clark S, Scott M, Podolski A, Ditterline JW, Morris MC, Moore H. Blood pressure changes associated with medication treatment of adults with attention-deficit/hyperactivity disorder. J Clin Psychiatry. 2005 Feb; 66(2):253-9.
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Hesse LM, He P, Krishnaswamy S, Hao Q, Hogan K, von Moltke LL, Greenblatt DJ, Court MH. Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes. Pharmacogenetics. 2004 Apr; 14(4):225-38.
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Zernig G, De Wit H, Telser S, Nienhusmeier M, Wakonigg G, Sturm K, Berger I, Kemmler G, Saria A. Subjective effects of slow-release bupropion versus caffeine as determined in a quasi-naturalistic setting. Pharmacology. 2004 Apr; 70(4):206-15.
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