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Sean P. David

TitleClinical Professor
InstitutionUniversity of Chicago
DepartmentFamily Medicine
AddressChicago IL 60637
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    Collapse Overview 
    Collapse overview
    I am a clinical and translational physician scientist with interests in alcohol and nicotine genomic discovery science, pharmacogenomics, precision medicine, tobacco cessation, implementation science, community-engaged research, and health equity. I am the NorthShore Site Leader for the Institute for Translational Medicine, Program Director for Translational Science for the Outcomes Research Network, and I am Vice Chair for Research for the Department of Family Medicine.

    Collapse Biography 
    Collapse education and training
    University of Washington, Seattle, WA, USABS 12/1990Zoology
    University of Washington, Seattle, WA, USAMD06/1995Medicine
    NH-Dartmouth Family Medicine Residency Program, Lebanon, NH, USANA06/1998Family Medicine
    Harvard T.H. Chan School of Public Health, Boston, MA, USASM06/1999Health & Social Behavior
    University of Oxford, Oxford, UKDPhil05/2006Pharmacology
    Harvard Business School, Boston, MA, USAPLDA07/2022Leadership/Business

    Collapse Research 
    Collapse research activities and funding
    R21DA027331     (DAVID, SEAN P.)Apr 1, 2009 - Mar 31, 2012
    NIH
    Exploratory/Developmental Study of Pharmacogenetic Smoking Cessation Therapy
    Role: Principal Investigator

    R01DA017441     (DAVID, SEAN P.)Sep 15, 2003 - Jun 30, 2016
    NIH
    Extended Treatment for Smoking Cessation
    Role: Principal Investigator

    R13CA101634     (DAVID, SEAN P.)Jun 1, 2003 - May 31, 2004
    NIH
    Primary Care Genetics Cancer Prevention Conference
    Role: Principal Investigator

    K08DA014276     (DAVID, SEAN P.)Sep 27, 2002 - May 31, 2008
    NIH
    Psychobiological /Genetic Determinants-Smoking Cessation
    Role: Principal Investigator

    Collapse Featured Content 
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. David S, Saulsberry L, Pruitt J, Dunnenberger H, Hulick P, Ward C. Effects of Social Determinants and Pharmacogenetic Medication Interactions on 90-Day Hospital Readmissions. Ann Fam Med. 2024 Nov 01; 21(Suppl 3). PMID: 38271180; PMCID: PMC10983206.
      Citations:    Fields:    Translation:Humans
    2. David SP, Dunnenberger HM, Choi S, DePersia A, Ilbawi N, Ward C, Wake DT, Khandekar JD, Shannon Y, Hughes K, Miller N, Mangold KA, Sabatini LM, Helseth DL, Xu J, Sanders A, Kaul KL, Hulick PJ. Personalized medicine in a community health system: the NorthShore experience. Front Genet. 2023; 14:1308738. PMID: 38090148; PMCID: PMC10713750.
      Citations:    
    3. Bricker JB, Santiago-Torres M, Mull KE, Sullivan BM, David SP, Schmitz J, Stotts A, Rigotti NA. Do medications increase the efficacy of digital interventions for smoking cessation? Secondary results from the iCanQuit randomized trial. Addiction. 2024 Apr; 119(4):664-676. PMID: 38009551; PMCID: PMC10932808.
      Citations:    Fields:    Translation:Humans
    4. Chen F, Wang X, Jang SK, Quach BC, Weissenkampen JD, Khunsriraksakul C, Yang L, Sauteraud R, Albert CM, Allred NDD, Arnett DK, Ashley-Koch AE, Barnes KC, Barr RG, Becker DM, Bielak LF, Bis JC, Blangero J, Boorgula MP, Chasman DI, Chavan S, Chen YI, Chuang LM, Correa A, Curran JE, David SP, Fuentes LL, Deka R, Duggirala R, Faul JD, Garrett ME, Gharib SA, Guo X, Hall ME, Hawley NL, He J, Hobbs BD, Hokanson JE, Hsiung CA, Hwang SJ, Hyde TM, Irvin MR, Jaffe AE, Johnson EO, Kaplan R, Kardia SLR, Kaufman JD, Kelly TN, Kleinman JE, Kooperberg C, Lee IT, Levy D, Lutz SM, Manichaikul AW, Martin LW, Marx O, McGarvey ST, Minster RL, Moll M, Moussa KA, Naseri T, North KE, Oelsner EC, Peralta JM, Peyser PA, Psaty BM, Rafaels N, Raffield LM, Reupena MS, Rich SS, Rotter JI, Schwartz DA, Shadyab AH, Sheu WH, Sims M, Smith JA, Sun X, Taylor KD, Telen MJ, Watson H, Weeks DE, Weir DR, Yanek LR, Young KA, Young KL, Zhao W, Hancock DB, Jiang B, Vrieze S, Liu DJ. Multi-ancestry transcriptome-wide association analyses yield insights into tobacco use biology and drug repurposing. Nat Genet. 2023 02; 55(2):291-300. PMID: 36702996; PMCID: PMC9925385.
      Citations: 10     Fields:    Translation:HumansCells
    5. Li X, Quick C, Zhou H, Gaynor SM, Liu Y, Chen H, Selvaraj MS, Sun R, Dey R, Arnett DK, Bielak LF, Bis JC, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Correa A, Cupples LA, Curran JE, de Vries PS, Duggirala R, Freedman BI, Guo X, Haessler J, Kalyani RR, Kooperberg C, Kral BG, Lange LA, Manichaikul A, Martin LW, McGarvey ST, Mitchell BD, Montasser ME, Morrison AC, Naseri T, O'Connell JR, Palmer ND, Peyser PA, Psaty BM, Raffield LM, Redline S, Reiner AP, Reupena MS, Rice KM, Rich SS, Sitlani CM, Smith JA, Taylor KD, Vasan RS, Willer CJ, Wilson JG, Yanek LR, Zhao W, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Lipids Working Group, Rotter JI, Natarajan P, Peloso GM, Li Z, Lin X, Göring HHH. Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies. Nat Genet. 2023 01; 55(1):154-164. PMID: 36564505; PMCID: PMC10084891.
      Citations: 6     Fields:    
    6. Saunders GRB, Wang X, Chen F, Jang SK, Liu M, Wang C, Gao S, Jiang Y, Khunsriraksakul C, Otto JM, Addison C, Akiyama M, Albert CM, Aliev F, Alonso A, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Barr RG, Bartz TM, Becker DM, Bielak LF, Benjamin EJ, Bis JC, Bjornsdottir G, Blangero J, Bleecker ER, Boardman JD, Boerwinkle E, Boomsma DI, Boorgula MP, Bowden DW, Brody JA, Cade BE, Chasman DI, Chavan S, Chen YI, Chen Z, Cheng I, Cho MH, Cole JW, Cornelis MC, Cucca F, Curran JE, de Andrade M, Dick DM, Docherty AR, Duggirala R, Eaton CB, Ehringer MA, Faul JD, Fernandes Silva L, Fiorillo E, Fornage M, Freedman BI, Gabrielsen ME, Garrett ME, Gharib SA, Gillespie N, Glahn DC, Gordon SD, Gu CC, Gu D, Gudbjartsson DF, Guo X, Haessler J, Hall ME, Haller T, Harris KM, He J, Herd P, Hewitt JK, Hickie I, Hidalgo B, Hokanson JE, Hopfer C, Hottenga J, Hou L, Huang H, Hung YJ, Hunter DJ, Hveem K, Hwang SJ, Hwu CM, Iacono W, Irvin MR, Jee YH, Johnson EO, Joo YY, Jorgenson E, Justice AE, Kamatani Y, Kaplan RC, Kaprio J, Kardia SLR, Keller MC, Kelly TN, Kooperberg C, Korhonen T, Kraft P, Krauter K, Kuusisto J, Laakso M, Lasky-Su J, Lee WJ, Lee JJ, Levy D, Li L, Li K, Li Y, Lin K, Lind PA, Liu C, Lloyd-Jones DM, Lutz SM, Ma J, Manichaikul A, Martin NG, Mathur R, Matoba N, McArdle PF, McGue M, McQueen MB, Medland SE, Metspalu A, Meyers DA, Millwood IY, Mitchell BD, Mohlke KL, Moll M, Montasser ME, Morrison AC, Mulas A, Nielsen JB, North KE, Oelsner EC, Okada Y, Palmer ND, Palviainen T, Pandit A, Park SL, Peters U, Peyser PA, Polderman TJC, Rafaels N, Redline S, Reed RM, Reiner AP, Rice JP, Rich SS, Richmond NE, Roan C, Rotter JI, Rueschman MN, Runarsdottir V, Saccone NL, Schwartz DA, Shadyab AH, Shi J, Shringarpure SS, Sicinski K, Skogholt AH, Smith JA, Smith NL, Sotoodehnia N, Stallings MC, Stefansson H, Stefansson K, Stitzel JA, Sun X, Syed M, Tal-Singer R, Taylor AE, Taylor KD, Telen MJ, Thai KK, Tiwari H, Turman C, Tyrfingsson T, Wall TL, Walters RG, Weir DR, Weiss ST, White WB, Whitfield JB, Wiggins KL, Willemsen G, Willer CJ, Winsvold BS, Xu H, Yanek LR, Yin J, Young KL, Young KA, Yu B, Zhao W, Zhou W, Zuccolo L, 23andMe Research Team, Biobank Japan Project, Batini C, Bergen AW, Bierut LJ, David SP, Hancock DB, Jiang B, Thorgeirsson TE, Liu DJ, Vrieze S, Choquet H, Esko T, Gieger C, Mägi R, Orrù V, Peters A, Zöllner S, Gagliano Taliun SA, Munafò MR. Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature. 2022 12; 612(7941):720-724. PMID: 36477530; PMCID: PMC9771818.
      Citations: 53     Fields:    Translation:HumansCells
    7. Gorukanti AL, Kimminau KS, Tindle HA, Klein JD, Gorzkowski J, Kaseeska K, Ali R, Singh L, David SP, Halpern-Felsher B. Cross-sectional online survey of clinicians' knowledge, attitudes and challenges to screening and counselling adolescents and young adults for substance use. BMJ Open. 2022 11 22; 12(11):e059019. PMID: 36414284; PMCID: PMC9685226.
      Citations: 1     Fields:    Translation:Humans
    8. Li Z, Li X, Zhou H, Gaynor SM, Selvaraj MS, Arapoglou T, Quick C, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Auer PL, Bielak LF, Bis JC, Blackwell TW, Blangero J, Boerwinkle E, Bowden DW, Brody JA, Cade BE, Conomos MP, Correa A, Cupples LA, Curran JE, de Vries PS, Duggirala R, Franceschini N, Freedman BI, Guo X, Kalyani RR, Kooperberg C, Kral BG, Lange LA, Lin BM, Manichaikul A, Manning AK, Martin LW, Mathias RA, Meigs JB, Mitchell BD, Montasser ME, Morrison AC, Naseri T, O'Connell JR, Palmer ND, Peyser PA, Psaty BM, Raffield LM, Redline S, Reiner AP, Reupena MS, Rice KM, Rich SS, Smith JA, Taylor KD, Taub MA, Vasan RS, Weeks DE, Wilson JG, Yanek LR, Zhao W, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Lipids Working Group, Rotter JI, Willer CJ, Natarajan P, Peloso GM, Lin X, Göring HHH. A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies. Nat Methods. 2022 12; 19(12):1599-1611. PMID: 36303018; PMCID: PMC10008172.
      Citations: 23     Fields:    Translation:Humans
    9. Selvaraj MS, Li X, Li Z, Pampana A, Zhang DY, Park J, Aslibekyan S, Bis JC, Brody JA, Cade BE, Chuang LM, Chung RH, Curran JE, de Las Fuentes L, de Vries PS, Duggirala R, Freedman BI, Graff M, Guo X, Heard-Costa N, Hidalgo B, Hwu CM, Irvin MR, Kelly TN, Kral BG, Lange L, Li X, Lisa M, Lubitz SA, Manichaikul AW, Michael P, Montasser ME, Morrison AC, Naseri T, O'Connell JR, Palmer ND, Peyser PA, Reupena MS, Smith JA, Sun X, Taylor KD, Tracy RP, Tsai MY, Wang Z, Wang Y, Bao W, Wilkins JT, Yanek LR, Zhao W, Arnett DK, Blangero J, Boerwinkle E, Bowden DW, Chen YI, Correa A, Cupples LA, Dutcher SK, Ellinor PT, Fornage M, Gabriel S, Germer S, Gibbs R, He J, Kaplan RC, Kardia SLR, Kim R, Kooperberg C, Loos RJF, Viaud-Martinez KA, Mathias RA, McGarvey ST, Mitchell BD, Nickerson D, North KE, Psaty BM, Redline S, Reiner AP, Vasan RS, Rich SS, Willer C, Rotter JI, Rader DJ, Lin X, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Peloso GM, Natarajan P. Whole genome sequence analysis of blood lipid levels in >66,000 individuals. Nat Commun. 2022 10 11; 13(1):5995. PMID: 36220816; PMCID: PMC9553944.
      Citations: 14     Fields:    Translation:Humans
    10. Tahir UA, Katz DH, Avila-Pachecho J, Bick AG, Pampana A, Robbins JM, Yu Z, Chen ZZ, Benson MD, Cruz DE, Ngo D, Deng S, Shi X, Zheng S, Eisman AS, Farrell L, Hall ME, Correa A, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Yao J, Chen YI, Manichaikul AW, Ruberg FL, Blaner WS, Jain D, NHLBI Trans-Omics for Precision Medicine 1 Consortium, Bouchard C, Sarzynski MA, Rich SS, Rotter JI, Wang TJ, Wilson JG, Clish CB, Natarajan P, Gerszten RE. Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals. Nat Commun. 2022 08 22; 13(1):4923. PMID: 35995766; PMCID: PMC9395431.
      Citations: 10     Fields:    Translation:Humans
    11. Nguyen LH, Anyane-Yeboa A, Klaser K, Merino J, Drew DA, Ma W, Mehta RS, Kim DY, Warner ET, Joshi AD, Graham MS, Sudre CH, Thompson EJ, May A, Hu C, Selvachandran S, Berry SE, David SP, Martinez ME, Figueiredo JC, Murray AM, Sanders AR, Koenen KC, Wolf J, Ourselin S, Spector TD, Steves CJ, Chan AT, Jørgensen S. The mental health burden of racial and ethnic minorities during the COVID-19 pandemic. PLoS One. 2022; 17(8):e0271661. PMID: 35947543; PMCID: PMC9365178.
      Citations: 13     Fields:    Translation:HumansPHPublic Health
    12. Jang SK, Evans L, Fialkowski A, Arnett DK, Ashley-Koch AE, Barnes KC, Becker DM, Bis JC, Blangero J, Bleecker ER, Boorgula MP, Bowden DW, Brody JA, Cade BE, Jenkins BWC, Carson AP, Chavan S, Cupples LA, Custer B, Damrauer SM, David SP, de Andrade M, Fingerlin TE, Fornage M, Freedman BI, Garrett ME, Gharib SA, Glahn DC, Haessler J, Heckbert SR, Hokanson JE, Hou L, Hwang SJ, Hyman MC, Judy R, Justice AE, Kaplan RC, Kardia SLR, Kelly S, Kim W, Kooperberg C, Levy D, Lloyd-Jones DM, Loos RJF, Manichaikul AW, Gladwin MT, Martin LW, Nouraie M, Meyers DA, Montgomery CG, North KE, Oelsner EC, Palmer ND, Payton M, Peljto AL, Peyser PA, Preuss M, Psaty BM, Qiao D, Rader DJ, Rafaels N, Redline S, Reed RM, Reiner AP, Rich SS, Rotter JI, Schwartz DA, Shadyab AH, Silverman EK, Smith NL, Smith JG, Smith AV, Smith JA, Tang W, Taylor KD, Telen MJ, Vasan RS, Gordeuk VR, Wang Z, Wiggins KL, Yanek LR, Yang IV, Young KA, Young KL, Zhang Y, Liu DJ, Keller MC, Vrieze S, Dinardo CL, Melander O. Rare genetic variants explain missing heritability in smoking. Nat Hum Behav. 2022 11; 6(11):1577-1586. PMID: 35927319; PMCID: PMC9985486.
      Citations: 6     Fields:    
    13. Saulsberry L, Singh L, Pruitt J, Ward C, Wake DT, Gibbons RD, Meltzer DO, O'Donnell PH, Cruz-Knight W, Hulick PJ, Dunnenberger HM, David SP. Effect Modification by Social Determinants of Pharmacogenetic Medication Interactions on 90-Day Hospital Readmissions within an Integrated U.S. Healthcare System. J Pers Med. 2022 Jul 15; 12(7). PMID: 35887642; PMCID: PMC9319564.
      Citations: 1     
    14. Menni C, Valdes AM, Polidori L, Antonelli M, Penamakuri S, Nogal A, Louca P, May A, Figueiredo JC, Hu C, Molteni E, Canas L, Modat M, Sudre CH, Fox B, Hammers A, Wolf J, Capdevila J, Chan AT, David SP, Steves CJ, Ourselin S, Spector TD, Österdahl MF. Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study. Lancet. 2022 04 23; 399(10335):1618-1624. PMID: 35397851; PMCID: PMC8989396.
      Citations: 316     Fields:    Translation:HumansCells
    15. Wainschtein P, Jain D, Zheng Z, TOPMed Anthropometry Working Group, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Cupples LA, Shadyab AH, McKnight B, Shoemaker BM, Mitchell BD, Psaty BM, Kooperberg C, Liu CT, Albert CM, Roden D, Chasman DI, Darbar D, Lloyd-Jones DM, Arnett DK, Regan EA, Boerwinkle E, Rotter JI, O'Connell JR, Yanek LR, de Andrade M, Allison MA, McDonald MN, Chung MK, Fornage M, Chami N, Smith NL, Ellinor PT, Vasan RS, Mathias RA, Loos RJF, Rich SS, Lubitz SA, Heckbert SR, Redline S, Guo X, Chen Y-I, Laurie CA, Hernandez RD, McGarvey ST, Goddard ME, Laurie CC, North KE, Lange LA, Weir BS, Yengo L, Yang J, Visscher PM. Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data. Nat Genet. 2022 03; 54(3):263-273. PMID: 35256806; PMCID: PMC9119698.
      Citations: 90     Fields:    Translation:Humans
    16. Luo Y, Kanai M, Choi W, Li X, Sakaue S, Yamamoto K, Ogawa K, Gutierrez-Arcelus M, Gregersen PK, Stuart PE, Elder JT, Forer L, Fuchsberger C, Smith AV, Fellay J, Carrington M, Haas DW, Guo X, Palmer ND, Chen YI, Rotter JI, Taylor KD, Rich SS, Correa A, Wilson JG, Kathiresan S, Cho MH, Metspalu A, Esko T, Okada Y, Han B, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, McLaren PJ, Raychaudhuri S, Schönherr S. Author Correction: A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response. Nat Genet. 2021 Dec; 53(12):1722. PMID: 34728834; PMCID: PMC8978071.
      Citations:    Fields:    
    17. Schuit E, Panagiotou OA, Bennett DA, Bergen AW, David SP, Munafò MR. Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers. Cochrane Database Syst Rev. 2021 11 30; 11:CD011823. PMID: 34847240; PMCID: PMC8631711.
      Citations:    Fields:    Translation:Humans
    18. Katz DH, Tahir UA, Bick AG, Pampana A, Ngo D, Benson MD, Yu Z, Robbins JM, Chen ZZ, Cruz DE, Deng S, Farrell L, Sinha S, Schmaier AA, Shen D, Gao Y, Hall ME, Correa A, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Yao J, Ida Chen YD, Manichaikul AW, Jain D, Bouchard C, Sarzynski MA, Rich SS, Rotter JI, Wang TJ, Wilson JG, Natarajan P, Gerszten RE, National Heart, Lung, and Blood Institute TOPMed (Trans-Omics for Precision Medicine) Consortium†. Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease. Circulation. 2022 02; 145(5):357-370. PMID: 34814699; PMCID: PMC9158509.
      Citations: 22     Fields:    Translation:Humans
    19. David SP, Singh L, Pruitt J, Hensing A, Hulick P, Meltzer DO, O'Donnell PH, Dunnenberger HM. The Contribution of Pharmacogenetic Drug Interactions to 90-Day Hospital Readmissions: Preliminary Results from a Real-World Healthcare System. J Pers Med. 2021 Nov 23; 11(12). PMID: 34945714; PMCID: PMC8705172.
      Citations: 3     
    20. Luo Y, Kanai M, Choi W, Li X, Sakaue S, Yamamoto K, Ogawa K, Gutierrez-Arcelus M, Gregersen PK, Stuart PE, Elder JT, Forer L, Fuchsberger C, Smith AV, Fellay J, Carrington M, Haas DW, Guo X, Palmer ND, Chen YI, Rotter JI, Taylor KD, Rich SS, Correa A, Wilson JG, Kathiresan S, Cho MH, Metspalu A, Esko T, Okada Y, Han B, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, McLaren PJ, Raychaudhuri S, Schönherr S. A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response. Nat Genet. 2021 10; 53(10):1504-1516. PMID: 34611364; PMCID: PMC8959399.
      Citations: 35     Fields:    Translation:HumansCells
    21. Cade BE, Lee J, Sofer T, Wang H, Zhang M, Chen H, Gharib SA, Gottlieb DJ, Guo X, Lane JM, Liang J, Lin X, Mei H, Patel SR, Purcell SM, Saxena R, Shah NA, Evans DS, Hanis CL, Hillman DR, Mukherjee S, Palmer LJ, Stone KL, Tranah GJ, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Boerwinkle EA, Correa A, Cupples LA, Kaplan RC, Nickerson DA, North KE, Psaty BM, Rotter JI, Rich SS, Tracy RP, Vasan RS, Wilson JG, Zhu X, Redline S, TOPMed Sleep Working Group, Abecasis GR. Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program. Genome Med. 2021 08 26; 13(1):136. PMID: 34446064; PMCID: PMC8394596.
      Citations: 10     Fields:    Translation:HumansCells
    22. David SP, Dunnenberger HM, Ali R, Matsil A, Lemke AA, Singh L, Zimmer A, Hulick PJ. Implementing Primary Care Mediated Population Genetic Screening Within an Integrated Health System. J Am Board Fam Med. 2021 Jul-Aug; 34(4):861-865. PMID: 34312282.
      Citations: 11     Fields:    Translation:Humans
    23. Keramati AR, Chen MH, Rodriguez BAT, Yanek LR, Bhan A, Gaynor BJ, Ryan K, Brody JA, Zhong X, Wei Q, NHLBI Trans-Omics for Precision (TOPMed) Consortium, Kammers K, Kanchan K, Iyer K, Kowalski MH, Pitsillides AN, Cupples LA, Li B, Schlaeger TM, Shuldiner AR, O'Connell JR, Ruczinski I, Mitchell BD, Faraday N, Taub MA, Becker LC, Lewis JP, Mathias RA, Johnson AD. Genome sequencing unveils a regulatory landscape of platelet reactivity. Nat Commun. 2021 06 15; 12(1):3626. PMID: 34131117; PMCID: PMC8206369.
      Citations: 22     Fields:    Translation:HumansCells
    24. Sofer T, Zheng X, Laurie CA, Gogarten SM, Brody JA, Conomos MP, Bis JC, Thornton TA, Szpiro A, O'Connell JR, Lange EM, Gao Y, Cupples LA, Psaty BM, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Rice KM. Variant-specific inflation factors for assessing population stratification at the phenotypic variance level. Nat Commun. 2021 06 09; 12(1):3506. PMID: 34108454; PMCID: PMC8190158.
      Citations: 2     Fields:    Translation:Humans
    25. Ikegami S, Benirschke RC, Fakhrai-Rad H, Motamedi MH, Hockett R, David S, Lee HK, Kang J, Gniadek TJ. Target specific serologic analysis of COVID-19 convalescent plasma. PLoS One. 2021; 16(4):e0249938. PMID: 33909632; PMCID: PMC8081213.
      Citations: 11     Fields:    Translation:HumansCells
    26. Kasela S, Ortega VE, Martorella M, Garudadri S, Nguyen J, Ampleford E, Pasanen A, Nerella S, Buschur KL, Barjaktarevic IZ, Barr RG, Bleecker ER, Bowler RP, Comellas AP, Cooper CB, Couper DJ, Criner GJ, Curtis JL, Han MK, Hansel NN, Hoffman EA, Kaner RJ, Krishnan JA, Martinez FJ, McDonald MN, Meyers DA, Paine R, Peters SP, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Israel E, Jarjour NN, Levy BD, Li X, Moore WC, Wenzel SE, Zein J, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS), NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Langelier C, Woodruff PG, Lappalainen T, Christenson SA. Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium. Genome Med. 2021 04 21; 13(1):66. PMID: 33883027; PMCID: PMC8059115.
      Citations: 16     Fields:    Translation:HumansCells
    27. Natarajan P, Pampana A, Graham SE, Ruotsalainen SE, Perry JA, de Vries PS, Broome JG, Pirruccello JP, Honigberg MC, Aragam K, Wolford B, Brody JA, Antonacci-Fulton L, Arden M, Aslibekyan S, Assimes TL, Ballantyne CM, Bielak LF, Bis JC, Cade BE, Do R, Doddapaneni H, Emery LS, Hung YJ, Irvin MR, Khan AT, Lange L, Lee J, Lemaitre RN, Martin LW, Metcalf G, Montasser ME, Moon JY, Muzny D, O'Connell JR, Palmer ND, Peralta JM, Peyser PA, Stilp AM, Tsai M, Wang FF, Weeks DE, Yanek LR, Wilson JG, Abecasis G, Arnett DK, Becker LC, Blangero J, Boerwinkle E, Bowden DW, Chang YC, Chen YI, Choi WJ, Correa A, Curran JE, Daly MJ, Dutcher SK, Ellinor PT, Fornage M, Freedman BI, Gabriel S, Germer S, Gibbs RA, He J, Hveem K, Jarvik GP, Kaplan RC, Kardia SLR, Kenny E, Kim RW, Kooperberg C, Laurie CC, Lee S, Lloyd-Jones DM, Loos RJF, Lubitz SA, Mathias RA, Martinez KAV, McGarvey ST, Mitchell BD, Nickerson DA, North KE, Palotie A, Park CJ, Psaty BM, Rao DC, Redline S, Reiner AP, Seo D, Seo JS, Smith AV, Tracy RP, Vasan RS, Kathiresan S, Cupples LA, Rotter JI, Morrison AC, Rich SS, Ripatti S, Willer C, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, FinnGen, Peloso GM. Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices. Nat Commun. 2021 04 12; 12(1):2182. PMID: 33846329; PMCID: PMC8042019.
      Citations: 7     Fields:    Translation:HumansCells
    28. McGuire D, Jiang Y, Liu M, Weissenkampen JD, Eckert S, Yang L, Chen F, GWAS and Sequencing Consortium of Alcohol and Nicotine Use (GSCAN), Berg A, Vrieze S, Jiang B, Li Q, Liu DJ. Model-based assessment of replicability for genome-wide association meta-analysis. Nat Commun. 2021 03 30; 12(1):1964. PMID: 33785739; PMCID: PMC8009871.
      Citations: 15     Fields:    
    29. Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Niroula A, Lin AE, Taub MA, Aguet F, Ardlie K, Mitchell BD, Barnes KC, Moscati A, Fornage M, Redline S, Psaty BM, Silverman EK, Weiss ST, Palmer ND, Vasan RS, Burchard EG, Kardia SLR, He J, Kaplan RC, Smith NL, Arnett DK, Schwartz DA, Correa A, de Andrade M, Guo X, Konkle BA, Custer B, Peralta JM, Gui H, Meyers DA, McGarvey ST, Chen IY, Shoemaker MB, Peyser PA, Broome JG, Gogarten SM, Wang FF, Wong Q, Montasser ME, Daya M, Kenny EE, North KE, Launer LJ, Cade BE, Bis JC, Cho MH, Lasky-Su J, Bowden DW, Cupples LA, Mak ACY, Becker LC, Smith JA, Kelly TN, Aslibekyan S, Heckbert SR, Tiwari HK, Yang IV, Heit JA, Lubitz SA, Johnsen JM, Curran JE, Wenzel SE, Weeks DE, Rao DC, Darbar D, Moon JY, Tracy RP, Buth EJ, Rafaels N, Loos RJF, Durda P, Liu Y, Hou L, Lee J, Kachroo P, Freedman BI, Levy D, Bielak LF, Hixson JE, Floyd JS, Whitsel EA, Ellinor PT, Irvin MR, Fingerlin TE, Raffield LM, Armasu SM, Wheeler MM, Blangero J, Williams LK, Levy BD, Sheu WH, Roden DM, Boerwinkle E, Manson JE, Mathias RA, Desai P, Taylor KD, Johnson AD, NHLBI Trans-Omics for Precision Medicine Consortium, Auer PL, Kooperberg C, Laurie CC, Blackwell TW, Smith AV, Zhao H, Lange E, Lange L, Rich SS, Rotter JI, Wilson JG, Scheet P, Kitzman JO, Lander ES, Engreitz JM, Ebert BL, Reiner AP, Jaiswal S, Sankaran VG, Kathiresan S, Natarajan P, Sabino EC, Abecasis G. Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. 2021 Mar; 591(7851):E27. PMID: 33707633.
      Citations: 2     Fields:    
    30. Taliun D, Harris DN, Kessler MD, Carlson J, Szpiech ZA, Torres R, Taliun SAG, Gogarten SM, Kang HM, Pitsillides AN, LeFaive J, Lee SB, Tian X, Browning BL, Das S, Emde AK, Clarke WE, Loesch DP, Shetty AC, Blackwell TW, Smith AV, Wong Q, Liu X, Conomos MP, Bobo DM, Albert C, Alonso A, Ardlie KG, Arking DE, Aslibekyan S, Auer PL, Barnard J, Barr RG, Barwick L, Becker LC, Beer RL, Benjamin EJ, Bielak LF, Blangero J, Boehnke M, Bowden DW, Brody JA, Burchard EG, Cade BE, Casella JF, Chalazan B, Chasman DI, Chen YI, Cho MH, Choi SH, Chung MK, Clish CB, Correa A, Curran JE, Custer B, Darbar D, Daya M, de Andrade M, DeMeo DL, Dutcher SK, Ellinor PT, Emery LS, Eng C, Fatkin D, Fingerlin T, Forer L, Fornage M, Franceschini N, Fuchsberger C, Fullerton SM, Germer S, Gladwin MT, Gottlieb DJ, Guo X, Hall ME, He J, Heard-Costa NL, Heckbert SR, Irvin MR, Johnsen JM, Johnson AD, Kaplan R, Kardia SLR, Kelly T, Kelly S, Kenny EE, Kiel DP, Klemmer R, Konkle BA, Kooperberg C, Lange LA, Lasky-Su J, Levy D, Lin X, Lin KH, Liu C, Loos RJF, Garman L, Gerszten R, Lubitz SA, Lunetta KL, Mak ACY, Manichaikul A, Manning AK, Mathias RA, McManus DD, McGarvey ST, Meigs JB, Meyers DA, Mikulla JL, Minear MA, Mitchell BD, Mohanty S, Montasser ME, Montgomery C, Morrison AC, Murabito JM, Natale A, Natarajan P, Nelson SC, North KE, O'Connell JR, Palmer ND, Pankratz N, Peloso GM, Peyser PA, Pleiness J, Post WS, Psaty BM, Rao DC, Redline S, Reiner AP, Roden D, Rotter JI, Ruczinski I, Schoenherr S, Schwartz DA, Seo JS, Seshadri S, Sheehan VA, Sheu WH, Shoemaker MB, Smith NL, Smith JA, Sotoodehnia N, Stilp AM, Tang W, Taylor KD, Telen M, Thornton TA, Tracy RP, Van Den Berg DJ, Vasan RS, Viaud-Martinez KA, Vrieze S, Weeks DE, Weir BS, Weiss ST, Weng LC, Willer CJ, Zhang Y, Zhao X, Arnett DK, Ashley-Koch AE, Barnes KC, Boerwinkle E, Gabriel S, Gibbs R, Rice KM, Rich SS, Silverman EK, Qasba P, Gan W, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Papanicolaou GJ, Nickerson DA, Browning SR, Zody MC, Wilson JG, Cupples LA, Laurie CC, Jaquish CE, Hernandez RD, O'Connor TD, Corvelo A, Aguet F, Köttgen A, Sarnowski C, Zöllner S, Abecasis GR. Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature. 2021 02; 590(7845):290-299. PMID: 33568819; PMCID: PMC7875770.
      Citations: 688     Fields:    Translation:Humans
    31. Reiner AP, Raffield LM, Franceschini N, Auer PL, Lange EM, Nickerson DA, Zakai NA, Correa A, Olson N, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine Consortium, Natinal Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine Consortium. Effect of Sickle Cell Trait and APOL1 Genotype on the Association of Soluble uPAR with Kidney Function Measures in Black Americans. Clin J Am Soc Nephrol. 2021 02 08; 16(2):287-289. PMID: 33268503; PMCID: PMC7863645.
      Citations: 1     Fields:    Translation:Humans
    32. Luvsantseren S, Whirl-Carrillo M, Sangkuhl K, Shin N, Wen A, Empey P, Alam B, David S, Dunnenberger HM, Orlando L, Altman R, Palaniappan L. Variant Interpretation in Current Pharmacogenetic Testing. J Pers Med. 2020 Oct 31; 10(4). PMID: 33142667; PMCID: PMC7712137.
      Citations: 2     
    33. Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Lin AE, Taub MA, Aguet F, Ardlie K, Mitchell BD, Barnes KC, Moscati A, Fornage M, Redline S, Psaty BM, Silverman EK, Weiss ST, Palmer ND, Vasan RS, Burchard EG, Kardia SLR, He J, Kaplan RC, Smith NL, Arnett DK, Schwartz DA, Correa A, de Andrade M, Guo X, Konkle BA, Custer B, Peralta JM, Gui H, Meyers DA, McGarvey ST, Chen IY, Shoemaker MB, Peyser PA, Broome JG, Gogarten SM, Wang FF, Wong Q, Montasser ME, Daya M, Kenny EE, North KE, Launer LJ, Cade BE, Bis JC, Cho MH, Lasky-Su J, Bowden DW, Cupples LA, Mak ACY, Becker LC, Smith JA, Kelly TN, Aslibekyan S, Heckbert SR, Tiwari HK, Yang IV, Heit JA, Lubitz SA, Johnsen JM, Curran JE, Wenzel SE, Weeks DE, Rao DC, Darbar D, Moon JY, Tracy RP, Buth EJ, Rafaels N, Loos RJF, Durda P, Liu Y, Hou L, Lee J, Kachroo P, Freedman BI, Levy D, Bielak LF, Hixson JE, Floyd JS, Whitsel EA, Ellinor PT, Irvin MR, Fingerlin TE, Raffield LM, Armasu SM, Wheeler MM, Blangero J, Williams LK, Levy BD, Sheu WH, Roden DM, Boerwinkle E, Manson JE, Mathias RA, Desai P, Taylor KD, Johnson AD, NHLBI Trans-Omics for Precision Medicine Consortium, Auer PL, Kooperberg C, Laurie CC, Blackwell TW, Smith AV, Zhao H, Lange E, Lange L, Rich SS, Rotter JI, Wilson JG, Scheet P, Kitzman JO, Lander ES, Engreitz JM, Ebert BL, Reiner AP, Jaiswal S, Sankaran VG, Kathiresan S, Natarajan P, Sabino EC, Abecasis G. Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. 2020 10; 586(7831):763-768. PMID: 33057201; PMCID: PMC7944936.
      Citations: 228     Fields:    Translation:HumansCells
    34. Li X, Li Z, Zhou H, Gaynor SM, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Aslibekyan S, Ballantyne CM, Bielak LF, Blangero J, Boerwinkle E, Bowden DW, Broome JG, Conomos MP, Correa A, Cupples LA, Curran JE, Freedman BI, Guo X, Hindy G, Irvin MR, Kardia SLR, Kathiresan S, Khan AT, Kooperberg CL, Laurie CC, Liu XS, Mahaney MC, Manichaikul AW, Martin LW, Mathias RA, McGarvey ST, Mitchell BD, Montasser ME, Moore JE, Morrison AC, O'Connell JR, Palmer ND, Pampana A, Peralta JM, Peyser PA, Psaty BM, Redline S, Rice KM, Rich SS, Smith JA, Tiwari HK, Tsai MY, Vasan RS, Wang FF, Weeks DE, Weng Z, Wilson JG, Yanek LR, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Lipids Working Group, Neale BM, Sunyaev SR, Rotter JI, Willer CJ, Peloso GM, Natarajan P, Lin X, Abecasis GR. Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. Nat Genet. 2020 09; 52(9):969-983. PMID: 32839606; PMCID: PMC7483769.
      Citations: 82     Fields:    Translation:Humans
    35. Eng VA, David SP, Li S, Ally MS, Stefanick M, Tang JY. The association between cigarette smoking, cancer screening, and cancer stage: a prospective study of the women's health initiative observational cohort. BMJ Open. 2020 08 13; 10(8):e037945. PMID: 32796021; PMCID: PMC7430331.
      Citations: 10     Fields:    Translation:Humans
    36. Rosas LG, Nasrallah C, Park VT, Vasquez JJ, Duron Y, Garrick O, Hattin R, Cho M, David SP, Evans J, McClinton-Brown R, Martin C. Perspectives on Precision Health Among Racial/Ethnic Minority Communities and the Physicians That Serve Them. Ethn Dis. 2020; 30(Suppl 1):137-148. PMID: 32269455; PMCID: PMC7138446.
      Citations: 13     Fields:    Translation:Humans
    37. Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J, Chaffin M, Engreitz J, Peloso GM, Manichaikul A, Yang C, Ryan KA, Fu M, Johnson WC, Tsai M, Budoff M, Vasan RS, Cupples LA, Rotter JI, Rich SS, Post W, Mitchell BD, Correa A, Metspalu A, Wilson JG, Salomaa V, Kellis M, Daly MJ, Neale BM, McCarroll S, Surakka I, Esko T, Ganna A, Ripatti S, Kathiresan S, Natarajan P, NHLBI TOPMed Lipids Working Group. Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. Nat Commun. 2020 Apr 01; 11(1):1715. PMID: 32238811; PMCID: PMC7113276.
      Citations: 1     Fields:    
    38. Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, Wang H, Daya M, Ziniti J, Datta S, Weiss ST, Barnes K, Redline SS, Vasan RS, Johnson AD, Mathias RA, Hernandez R, Wilson JG, Nickerson DA, Abecasis G, Browning SR, O'Connell JR, Mitchell BD, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Population Genetics Working Group, O'Connor TD, Celedón JC, Soto-Quiros ME, Avila L, Zöllner S. De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population. Proc Natl Acad Sci U S A. 2020 02 04; 117(5):2560-2569. PMID: 31964835; PMCID: PMC7007577.
      Citations: 37     Fields:    Translation:Humans
    39. Oshman L, Caplan A, Ali R, Singh L, Khalid R, Jameel M, David SP. Whom Should We Test for COVID-19? Performance of a Symptom and Risk Factor Questionnaire on COVID-19 Test Results and Patient Outcomes in an Immediate Care Setting. J Prim Care Community Health. 2020 Jan-Dec; 11:2150132720981297. PMID: 33300408; PMCID: PMC7734557.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    40. Kachroo P, Hecker J, Chawes BL, Ahluwalia TS, Cho MH, Qiao D, Kelly RS, Chu SH, Virkud YV, Huang M, Barnes KC, Burchard EG, Eng C, Hu D, Daya M, Levin AM, Gui H, Williams LK, Forno E, Mak ACY, Cloutier MM, Canino G, Bisgaard H, Raby BA, Lange C, Weiss ST, Lasky-Su JA, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium, Celedón JC, Avila L, Soto-Quiros ME, Acosta-Pérez E, Bønnelykke K. Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma. Chest. 2019 12; 156(6):1068-1079. PMID: 31557467; PMCID: PMC6904857.
      Citations: 4     Fields:    Translation:Humans
    41. Panagiotou OA, Schuit E, Bennett DA, Bergen AW, David SP, Munafò MR. Smoking Cessation Pharmacotherapy Based on Genetically-Informed Biomarkers: What is the Evidence? Nicotine Tob Res. 2019 08 19; 21(9):1289-1293. PMID: 30690475; PMCID: PMC6698953.
      Citations: 4     Fields:    Translation:Humans
    42. Bergen AW, Do EK, Chen LS, David SP. Tobacco Genomics: Complexity and Translational Challenges. Nicotine Tob Res. 2019 05 21; 21(6):705-706. PMID: 31111930; PMCID: PMC6528148.
      Citations: 1     Fields:    
    43. Liu M, Jiang Y, Wedow R, Li Y, Brazel DM, Chen F, Datta G, Davila-Velderrain J, McGuire D, Tian C, Zhan X, 23andMe Research Team, HUNT All-In Psychiatry, Docherty AR, Faul JD, Foerster JR, Fritsche LG, Gabrielsen ME, Gordon SD, Haessler J, Hottenga JJ, Huang H, Jang SK, Jansen PR, Ling Y, Matoba N, McMahon G, Mulas A, Palviainen T, Pandit A, Reginsson GW, Skogholt AH, Smith JA, Taylor AE, Turman C, Willemsen G, Young H, Young KA, Zajac GJM, Zhao W, Zhou W, Bjornsdottir G, Boardman JD, Boehnke M, Boomsma DI, Chen C, Cucca F, Davies GE, Eaton CB, Ehringer MA, Fiorillo E, Gillespie NA, Gudbjartsson DF, Haller T, Harris KM, Heath AC, Hewitt JK, Hickie IB, Hokanson JE, Hopfer CJ, Hunter DJ, Iacono WG, Johnson EO, Kamatani Y, Kardia SLR, Keller MC, Kellis M, Kooperberg C, Kraft P, Krauter KS, Laakso M, Lind PA, Loukola A, Lutz SM, Madden PAF, Martin NG, McGue M, McQueen MB, Medland SE, Metspalu A, Mohlke KL, Nielsen JB, Okada Y, Peters U, Polderman TJC, Posthuma D, Reiner AP, Rice JP, Rimm E, Rose RJ, Runarsdottir V, Stallings MC, Stefansson H, Thai KK, Tindle HA, Tyrfingsson T, Wall TL, Weir DR, Weisner C, Whitfield JB, Winsvold BS, Yin J, Zuccolo L, Bierut LJ, Hveem K, Lee JJ, Saccone NL, Willer CJ, Cornelis MC, David SP, Hinds DA, Jorgenson E, Kaprio J, Stitzel JA, Stefansson K, Thorgeirsson TE, Liu DJ, Vrieze S, Choquet H, Mägi R, Orrù V, Esko T, Stancáková A, Munafò MR, Abecasis G. Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use. Nat Genet. 2019 02; 51(2):237-244. PMID: 30643251; PMCID: PMC6358542.
      Citations: 712     Fields:    Translation:Humans
    44. Erzurumluoglu AM, Liu M, Jackson VE, Barnes DR, Datta G, Melbourne CA, Young R, Batini C, Surendran P, Jiang T, Adnan SD, Afaq S, Agrawal A, Antoniou AC, Asselbergs FW, Bierut L, Bertelsen S, Boehnke M, Bots ML, Brazel DM, Chambers JC, Chang-Claude J, Chen C, Corley J, Chou YL, David SP, de Boer RA, de Leeuw CA, Dennis JG, Dominiczak AF, Dunning AM, Easton DF, Eaton C, Elliott P, Evangelou E, Faul JD, Foroud T, Goate A, Gong J, Grabe HJ, Haessler J, Haiman C, Hammerschlag AR, Harris SE, Hattersley A, Heath A, Hsu C, Iacono WG, Kanoni S, Kapoor M, Kaprio J, Kardia SL, Karpe F, Kontto J, Kooner JS, Kooperberg C, Kuulasmaa K, Laakso M, Lai D, Langenberg C, Le N, Lettre G, Loukola A, Luan J, Madden PAF, Mangino M, Marioni RE, Marouli E, Marten J, Martin NG, McGue M, Michailidou K, Mihailov E, Moayyeri A, Moitry M, Naheed A, Nauck M, Neville MJ, Nielsen SF, North K, Perola M, Pharoah PDP, Pistis G, Polderman TJ, Posthuma D, Poulter N, Qaiser B, Rasheed A, Reiner A, Rice J, Rohde R, Samani NJ, Samuel M, Schlessinger D, Scholte SH, Scott RA, Sever P, Shao Y, Shrine N, Smith JA, Starr JM, Stirrups K, Stram D, Stringham HM, Tachmazidou I, Tardif JC, Thompson DJ, Tindle HA, Tragante V, Trompet S, Turcot V, Tyrrell J, Vaartjes I, van der Leij AR, van der Meer P, Verweij N, Wareham NJ, Warren HR, Weir DR, Weiss S, Wetherill L, Yaghootkar H, Yavas E, Jiang Y, Chen F, Zhan X, Zhang W, Zhao W, Zhao W, Zhou K, Amouyel P, Blankenberg S, Caulfield MJ, Chowdhury R, Cucca F, Deary IJ, Deloukas P, Di Angelantonio E, Ferrario M, Frayling TM, Frossard P, Hall IP, Hayward C, Jukema JW, Kee F, Metspalu A, Munroe PB, Palmer CNA, Salomaa V, Sattar N, Spector T, Strachan DP, Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviou, van der Harst P, Zeggini E, Saleheen D, Butterworth AS, Wain LV, Abecasis GR, Danesh J, Tobin MD, Vrieze S, Liu DJ, Howson JMM, Altmaier E, Baumbach C, Hallmans G, Müller-Nurasyid M, Renström F, Rolandsson O, Varga TV, Völzke H, Ferrières J, Franks PW, Jansson JH, Männistö S, Nordestgaard BG. Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. Mol Psychiatry. 2020 10; 25(10):2392-2409. PMID: 30617275; PMCID: PMC7515840.
      Citations: 52     Fields:    Translation:Humans
    45. Brazel DM, Jiang Y, Hughey JM, Zhan X, Gong J, Batini C, Weissenkampen JD, Liu M, CHD Exome+ Consortium, Consortium for Genetics of Smoking Behaviour, Barnes DR, Bertelsen S, Chou YL, Erzurumluoglu AM, Faul JD, Haessler J, Hammerschlag AR, Hsu C, Kapoor M, Lai D, Le N, de Leeuw CA, Loukola A, Mangino M, Melbourne CA, Pistis G, Qaiser B, Rohde R, Shao Y, Stringham H, Wetherill L, Zhao W, Agrawal A, Bierut L, Chen C, Eaton CB, Goate A, Haiman C, Heath A, Iacono WG, Martin NG, Polderman TJ, Reiner A, Rice J, Schlessinger D, Scholte HS, Smith JA, Tindle HA, van der Leij AR, Boehnke M, Chang-Claude J, Cucca F, David SP, Foroud T, Howson JMM, Kardia SLR, Kooperberg C, Laakso M, Madden P, McGue M, North K, Posthuma D, Spector T, Stram D, Tobin MD, Weir DR, Kaprio J, Liu DJ, Vrieze S, Turcot V, Tardif JC, Lettre G, Abecasis GR. Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Biol Psychiatry. 2019 06 01; 85(11):946-955. PMID: 30679032; PMCID: PMC6534468.
      Citations: 33     Fields:    Translation:Humans
    46. Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J, Chaffin M, Engreitz J, Peloso GM, Manichaikul A, Yang C, Ryan KA, Fu M, Johnson WC, Tsai M, Budoff M, Vasan RS, Cupples LA, Rotter JI, Rich SS, Post W, Mitchell BD, Correa A, Metspalu A, Wilson JG, Salomaa V, Kellis M, Daly MJ, Neale BM, McCarroll S, Surakka I, Esko T, Ganna A, Ripatti S, Kathiresan S, Natarajan P, NHLBI TOPMed Lipids Working Group. Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. Nat Commun. 2018 08 23; 9(1):3493. PMID: 30140049; PMCID: PMC6107495.
      Citations: 1     Fields:    
    47. Natarajan P, Peloso GM, Zekavat SM, Montasser M, Ganna A, Chaffin M, Khera AV, Zhou W, Bloom JM, Engreitz JM, Ernst J, O'Connell JR, Ruotsalainen SE, Alver M, Manichaikul A, Johnson WC, Perry JA, Poterba T, Seed C, Surakka IL, Esko T, Ripatti S, Salomaa V, Correa A, Vasan RS, Kellis M, Neale BM, Lander ES, Abecasis G, Mitchell B, Rich SS, Wilson JG, Cupples LA, Rotter JI, Willer CJ, Kathiresan S, NHLBI TOPMed Lipids Working Group. Deep-coverage whole genome sequences and blood lipids among 16,324 individuals. Nat Commun. 2018 08 23; 9(1):3391. PMID: 30140000; PMCID: PMC6107638.
      Citations: 69     Fields:    Translation:HumansCells
    48. Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J, Chaffin M, Engreitz J, Peloso GM, Manichaikul A, Yang C, Ryan KA, Fu M, Johnson WC, Tsai M, Budoff M, Vasan RS, Cupples LA, Rotter JI, Rich SS, Post W, Mitchell BD, Correa A, Metspalu A, Wilson JG, Salomaa V, Kellis M, Daly MJ, Neale BM, McCarroll S, Surakka I, Esko T, Ganna A, Ripatti S, Kathiresan S, Natarajan P, NHLBI TOPMed Lipids Working Group. Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. Nat Commun. 2018 07 04; 9(1):2606. PMID: 29973585; PMCID: PMC6031652.
      Citations: 44     Fields:    Translation:Humans
    49. Salloum NC, Buchalter ELF, Chanani S, Espejo G, Ismail MS, Laine RO, Nageeb M, Srivastava AB, Trapp N, Trillo L, Vance E, Wenzinger M, Hartz SM, David SP, Chen LS. From genes to treatments: a systematic review of the pharmacogenetics in smoking cessation. Pharmacogenomics. 2018 07 01; 19(10):861-871. PMID: 29914292; PMCID: PMC6219447.
      Citations: 8     Fields:    Translation:Humans
    50. David SP, Palaniappan L. Clinical and Personal Utility of Genetic Risk Testing. Am Fam Physician. 2018 05 01; 97(9):600-602. PMID: 29763257.
      Citations: 2     Fields:    Translation:Humans
    51. David SP, Naudet F, Laude J, Radua J, Fusar-Poli P, Chu I, Stefanick ML, Ioannidis JPA. Potential Reporting Bias in Neuroimaging Studies of Sex Differences. Sci Rep. 2018 04 17; 8(1):6082. PMID: 29666377; PMCID: PMC5904173.
      Citations: 29     Fields:    Translation:Humans
    52. Chen LS, Zawertailo L, Piasecki TM, Kaprio J, Foreman M, Elliott HR, David SP, Bergen AW, Baurley JW, Tyndale RF, Baker TB, Bierut LJ, Saccone NL, Genetics and Treatment Workgroup of the Society for Research on Nicotine and Tobacco (SRNT). Leveraging Genomic Data in Smoking Cessation Trials in the Era of Precision Medicine: Why and How. Nicotine Tob Res. 2018 03 06; 20(4):414-424. PMID: 28498934; PMCID: PMC5896450.
      Citations: 13     Fields:    Translation:Humans
    53. Saccone NL, Baurley JW, Bergen AW, David SP, Elliott HR, Foreman MG, Kaprio J, Piasecki TM, Relton CL, Zawertailo L, Bierut LJ, Tyndale RF, Chen LS, Genetics and Treatment Networks of the Society for Research on Nicotine and Tobacco (SRNT). The Value of Biosamples in Smoking Cessation Trials: A Review of Genetic, Metabolomic, and Epigenetic Findings. Nicotine Tob Res. 2018 03 06; 20(4):403-413. PMID: 28472521; PMCID: PMC5896536.
      Citations: 11     Fields:    Translation:Humans
    54. Satizabal CL, DeCarli C, Pitsillides AN, Cupples LA, Vasan RS, Wilson JG, Bis JC, Fornage M, Beiser AS, DeStefano AL, Seshadri S, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Neurocognitive Working Group, Sarnowski C, Dupuis J. Whole genome sequence analyses of brain imaging measures in the Framingham Study. Neurology. 2018 01 16; 90(3):e188-e196. PMID: 29282330; PMCID: PMC5772158.
      Citations: 17     Fields:    Translation:Humans
    55. Puryear L, Downs N, Nevedal A, Lewis ET, Ormond KE, Bregendahl M, Suarez CJ, David SP, Charlap S, Chu I, Asch SM, Pakdaman N, Chang SI, Cullen MR, Palaniappan L. Patient and provider perspectives on the development of personalized medicine: a mixed-methods approach. J Community Genet. 2018 Jul; 9(3):283-291. PMID: 29280052; PMCID: PMC6002302.
      Citations: 12     
    56. Schuit E, Panagiotou OA, Bennett DA, Bergen AW, David SP, Munafò MR. Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers. Cochrane Database Syst Rev. 2017 09 08; 9:CD011823. PMID: 28884473; PMCID: PMC6483659.
      Citations: 22     Fields:    Translation:Humans
    57. Laude JR, Bailey SR, Crew E, Varady A, Lembke A, McFall D, Jeon A, Killen D, Killen JD, David SP. Extended treatment for cigarette smoking cessation: a randomized control trial. Addiction. 2017 Aug; 112(8):1451-1459. PMID: 28239942; PMCID: PMC5503769.
      Citations: 9     Fields:    Translation:Humans
    58. David SP. Novel Methodologies and the Need for Big Data in Nicotine and Tobacco Genetics Research. Nicotine Tob Res. 2017 04 01; 19(4):385-386. PMID: 28393169.
      Citations:    Fields:    
    59. Shields PG, Herbst RS, Arenberg D, Benowitz NL, Bierut L, Luckart JB, Cinciripini P, Collins B, David S, Davis J, Hitsman B, Hyland A, Lang M, Leischow S, Park ER, Purcell WT, Selzle J, Silber A, Spencer S, Tanvetyanon T, Tiep B, Tindle HA, Tucker-Seeley R, Urbanic J, Hooper MW, Weksler B, Whitlock CW, Wood DE, Burns J, Scavone J. Smoking Cessation, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2016 11; 14(11):1430-1468. PMID: 27799513.
      Citations: 85     Fields:    Translation:Humans
    60. Leyro TM, Crew EE, Bryson SW, Lembke A, Bailey SR, Prochaska JJ, Henriksen L, Fortmann SP, Killen JD, Killen DT, Hall SM, David SP. Retrospective analysis of changing characteristics of treatment-seeking smokers: implications for further reducing smoking prevalence. BMJ Open. 2016 06 29; 6(6):e010960. PMID: 27357195; PMCID: PMC4932265.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    61. Ockene JK, Hayes RB, Churchill LC, Crawford SL, Jolicoeur DG, Murray DM, Shoben AB, David SP, Ferguson KJ, Huggett KN, Adams M, Okuliar CA, Gross RL, Bass PF, Greenberg RB, Leone FT, Okuyemi KS, Rudy DW, Waugh JB, Geller AC. Teaching Medical Students to Help Patients Quit Smoking: Outcomes of a 10-School Randomized Controlled Trial. J Gen Intern Med. 2016 Feb; 31(2):172-181. PMID: 26391030; PMCID: PMC4720645.
      Citations: 25     Fields:    Translation:Humans
    62. David SP, Wang A, Kapphahn K, Hedlin H, Desai M, Henderson M, Yang L, Walsh KM, Schwartz AG, Wiencke JK, Spitz MR, Wenzlaff AS, Wrensch MR, Eaton CB, Furberg H, Mark Brown W, Goldstein BA, Assimes T, Tang H, Kooperberg CL, Quesenberry CP, Tindle H, Patel MI, Amos CI, Bergen AW, Swan GE, Stefanick ML. Gene by Environment Investigation of Incident Lung Cancer Risk in African-Americans. EBioMedicine. 2016 Feb; 4:153-61. PMID: 26981579; PMCID: PMC4776066.
      Citations: 8     Fields:    Translation:HumansCells
    63. David SP, Amos CI. Gene by Environment Interaction Linking the Chromosome 15q25 Locus with Cigarette Consumption and Lung Cancer Susceptibility--Are African American Affected Differently?--Authors' Reply. EBioMedicine. 2016 Feb; 4:15. PMID: 26981563; PMCID: PMC4776065.
      Citations:    Fields:    Translation:HumansCells
    64. Weng DY, Chen J, Taslim C, Hsu PC, Marian C, David SP, Loffredo CA, Shields PG. Persistent alterations of gene expression profiling of human peripheral blood mononuclear cells from smokers. Mol Carcinog. 2016 10; 55(10):1424-37. PMID: 26294040; PMCID: PMC4860148.
      Citations: 4     Fields:    Translation:HumansCells
    65. David SP, Johnson SG, Berger AC, Feero WG, Terry SF, Green LA, Phillips RL, Ginsburg GS. Making Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable. Ann Fam Med. 2015 Jul-Aug; 13(4):373-80. PMID: 26195686; PMCID: PMC4508182.
      Citations: 17     Fields:    Translation:Humans
    66. Hayes RB, Geller AC, Crawford SL, Jolicoeur DG, Churchill LC, Okuyemi KS, David SP, Adams M, Waugh J, Allen SS, Leone FT, Fauver R, Leung K, Liu Q, Ockene JK. Medical school curriculum characteristics associated with intentions and frequency of tobacco dependence treatment among 3rd year U.S. medical students. Prev Med. 2015 Mar; 72:56-63. PMID: 25572623; PMCID: PMC4562320.
      Citations: 6     Fields:    Translation:Humans
    67. Henderson MT, Kubo JT, Desai M, David SP, Tindle H, Sinha AA, Seiffert-Sinha K, Hou L, Messina C, Saquib N, Stefanick ML, Tang JY. Smoking behavior and association of melanoma and nonmelanoma skin cancer in the Women's Health Initiative. J Am Acad Dermatol. 2015 Jan; 72(1):190-1.e3. PMID: 25497923; PMCID: PMC4509504.
      Citations: 9     Fields:    Translation:Humans
    68. Strong DR, David SP, Johnstone EC, Aveyard P, Murphy MF, Munafò MR. Differential Efficacy of Nicotine Replacement Among Overweight and Obese Women Smokers. Nicotine Tob Res. 2015 Jul; 17(7):855-61. PMID: 25481918; PMCID: PMC4542679.
      Citations: 2     Fields:    Translation:Humans
    69. Zhu AZ, Zhou Q, Cox LS, David SP, Ahluwalia JS, Benowitz NL, Tyndale RF. Association of CHRNA5-A3-B4 SNP rs2036527 with smoking cessation therapy response in African-American smokers. Clin Pharmacol Ther. 2014 Aug; 96(2):256-65. PMID: 24733007; PMCID: PMC4111775.
      Citations: 34     Fields:    Translation:Humans
    70. Passarelli MN, Newcomb PA, Makar KW, Burnett-Hartman AN, Phipps AI, David SP, Hsu L, Harrison TA, Hutter CM, Duggan DJ, White E, Chan AT, Peters U. No association between germline variation in catechol-O-methyltransferase and colorectal cancer survival in postmenopausal women. Menopause. 2014 Apr; 21(4):415-20. PMID: 23880798; PMCID: PMC3865220.
      Citations: 2     Fields:    Translation:Humans
    71. Xu X, Clark US, David SP, Mulligan RC, Knopik VS, McGeary J, MacKillop J, McCaffery J, Niaura RS, Sweet LH. Effects of nicotine deprivation and replacement on BOLD-fMRI response to smoking cues as a function of DRD4 VNTR genotype. Nicotine Tob Res. 2014 Jul; 16(7):939-47. PMID: 24659022; PMCID: PMC4072897.
      Citations: 7     Fields:    Translation:HumansCells
    72. Ioannidis JP, Fusar-Poli P, Nosek BA, David SP, Munafò MR. Publication and other reporting biases in cognitive sciences: detection, prevalence, and prevention. Trends Cogn Sci. 2014 May; 18(5):235-41. PMID: 24656991; PMCID: PMC4078993.
      Citations: 129     Fields:    Translation:Humans
    73. David SP, Chu IM, Lancaster T, Stead LF, Evins AE, Prochaska JJ. Systematic review and meta-analysis of opioid antagonists for smoking cessation. BMJ Open. 2014 Mar 14; 4(3):e004393. PMID: 24633528; PMCID: PMC3963070.
      Citations: 17     Fields:    Translation:Humans
    74. Dewey FE, Grove ME, Pan C, Goldstein BA, Bernstein JA, Chaib H, Merker JD, Goldfeder RL, Enns GM, David SP, Pakdaman N, Ormond KE, Caleshu C, Kingham K, Klein TE, Whirl-Carrillo M, Sakamoto K, Wheeler MT, Butte AJ, Ford JM, Boxer L, Ioannidis JP, Yeung AC, Altman RB, Assimes TL, Snyder M, Ashley EA, Quertermous T. Clinical interpretation and implications of whole-genome sequencing. JAMA. 2014 Mar 12; 311(10):1035-45. PMID: 24618965; PMCID: PMC4119063.
      Citations: 217     Fields:    Translation:Humans
    75. Hayes RB, Geller A, Churchill L, Jolicoeur D, Murray DM, Shoben A, David SP, Adams M, Okuyemi K, Fauver R, Gross R, Leone F, Xiao R, Waugh J, Crawford S, Ockene JK. Teaching tobacco dependence treatment and counseling skills during medical school: rationale and design of the Medical Students helping patients Quit tobacco (MSQuit) group randomized controlled trial. Contemp Clin Trials. 2014 Mar; 37(2):284-93. PMID: 24486635; PMCID: PMC4048818.
      Citations: 10     Fields:    Translation:Humans
    76. David SP. Commentary on Chen et?al. (2014): another step on the road to clinical utility of pharmacogenetics for smoking cessation? Addiction. 2014 Jan; 109(1):138-9. PMID: 24438115.
      Citations: 2     Fields:    Translation:Humans
    77. Fusar-Poli P, Radua J, Frascarelli M, Mechelli A, Borgwardt S, Di Fabio F, Biondi M, Ioannidis JP, David SP. Evidence of reporting biases in voxel-based morphometry (VBM) studies of psychiatric and neurological disorders. Hum Brain Mapp. 2014 Jul; 35(7):3052-65. PMID: 24123491; PMCID: PMC6869352.
      Citations: 28     Fields:    Translation:Humans
    78. David SP, Strong DR, Leventhal AM, Lancaster MA, McGeary JE, Bergen AW, Swan GE, Benowitz NL, Tyndale RF, Conti DV, Brown RA, Lerman C, Niaura R, Munafò MR. Influence of a dopamine pathway additive genetic efficacy score on smoking cessation: results from two randomized clinical trials of bupropion. Addiction. 2013 Dec; 108(12):2202-11. PMID: 23941313; PMCID: PMC3834197.
      Citations: 20     Fields:    Translation:HumansCells
    79. David SP, Ware JJ, Chu IM, Loftus PD, Fusar-Poli P, Radua J, Ioannidis JP, Munafò MR. Potential reporting bias in fMRI studies of the brain. PLoS One. 2013; 8(7):e70104. PMID: 23936149; PMCID: PMC3723634.
      Citations: 49     Fields:    Translation:Humans
    80. David SP, Lancaster T, Stead LF, Evins AE, Prochaska JJ. Opioid antagonists for smoking cessation. Cochrane Database Syst Rev. 2013 Jun 06; (6):CD003086. PMID: 23744347; PMCID: PMC4038652.
      Citations: 21     Fields:    Translation:Humans
    81. Griswold KS, Lesko SE, Westfall JM, Folsom Group. Communities of solution: partnerships for population health. J Am Board Fam Med. 2013 May-Jun; 26(3):232-8. PMID: 23657688.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    82. Geller AC, Hayes RB, Leone F, Churchill LC, Leung K, Reed G, Jolicoeur D, Okuliar C, Adams M, Murray DM, Liu Q, Waugh J, David S, Ockene JK. Tobacco dependence treatment teaching by medical school clerkship preceptors: survey responses from more than 1,000 US medical students. Prev Med. 2013 Aug; 57(2):81-6. PMID: 23623894; PMCID: PMC3767283.
      Citations: 8     Fields:    Translation:Humans
    83. Bough KJ, Lerman C, Rose JE, McClernon FJ, Kenny PJ, Tyndale RF, David SP, Stein EA, Uhl GR, Conti DV, Green C, Amur S. Biomarkers for smoking cessation. Clin Pharmacol Ther. 2013 Jun; 93(6):526-38. PMID: 23588313; PMCID: PMC3772534.
      Citations: 39     Fields:    Translation:Humans
    84. McClure JB, Swan GE, St John J, Fauver R, Javitz HS, Bergen AW, Nishita D, Niaura R, David SP, Munafò MR. Pharmacogenetic smoking cessation intervention in a health care setting: a pilot feasibility study. Nicotine Tob Res. 2013 Feb; 15(2):518-26. PMID: 22949583; PMCID: PMC3611995.
      Citations: 10     Fields:    Translation:Humans
    85. McDonagh EM, Wassenaar C, David SP, Tyndale RF, Altman RB, Whirl-Carrillo M, Klein TE. PharmGKB summary: very important pharmacogene information for cytochrome P-450, family 2, subfamily A, polypeptide 6. Pharmacogenet Genomics. 2012 Sep; 22(9):695-708. PMID: 22547082; PMCID: PMC3413746.
      Citations: 31     Fields:    Translation:Humans
    86. American Board of Family Medicine Young Leaders Advisory Group. Improving America's health requires community-level solutions: Folsom revisited. Am Fam Physician. 2012 Aug 15; 86(4):1-2. PMID: 23130357.
      Citations:    Fields:    Translation:Humans
    87. David SP, Hamidovic A, Chen GK, Bergen AW, Wessel J, Kasberger JL, Brown WM, Petruzella S, Thacker EL, Kim Y, Nalls MA, Tranah GJ, Sung YJ, Ambrosone CB, Arnett D, Bandera EV, Becker DM, Becker L, Berndt SI, Bernstein L, Blot WJ, Broeckel U, Buxbaum SG, Caporaso N, Casey G, Chanock SJ, Deming SL, Diver WR, Eaton CB, Evans DS, Evans MK, Fornage M, Franceschini N, Harris TB, Henderson BE, Hernandez DG, Hitsman B, Hu JJ, Hunt SC, Ingles SA, John EM, Kittles R, Kolb S, Kolonel LN, Le Marchand L, Liu Y, Lohman KK, McKnight B, Millikan RC, Murphy A, Neslund-Dudas C, Nyante S, Press M, Psaty BM, Rao DC, Redline S, Rodriguez-Gil JL, Rybicki BA, Signorello LB, Singleton AB, Smoller J, Snively B, Spring B, Stanford JL, Strom SS, Swan GE, Taylor KD, Thun MJ, Wilson AF, Witte JS, Yamamura Y, Yanek LR, Yu K, Zheng W, Ziegler RG, Zonderman AB, Jorgenson E, Haiman CA, Furberg H. Genome-wide meta-analyses of smoking behaviors in African Americans. Transl Psychiatry. 2012 May 22; 2:e119. PMID: 22832964; PMCID: PMC3365260.
      Citations: 66     Fields:    Translation:HumansCells
    88. Chen LS, Saccone NL, Culverhouse RC, Bracci PM, Chen CH, Dueker N, Han Y, Huang H, Jin G, Kohno T, Ma JZ, Przybeck TR, Sanders AR, Smith JA, Sung YJ, Wenzlaff AS, Wu C, Yoon D, Chen YT, Cheng YC, Cho YS, David SP, Duan J, Eaton CB, Furberg H, Goate AM, Gu D, Hansen HM, Hartz S, Hu Z, Kim YJ, Kittner SJ, Levinson DF, Mosley TH, Payne TJ, Rao DC, Rice JP, Rice TK, Schwantes-An TH, Shete SS, Shi J, Spitz MR, Sun YV, Tsai FJ, Wang JC, Wrensch MR, Xian H, Gejman PV, He J, Hunt SC, Kardia SL, Li MD, Lin D, Mitchell BD, Park T, Schwartz AG, Shen H, Wiencke JK, Wu JY, Yokota J, Amos CI, Bierut LJ. Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25. Genet Epidemiol. 2012 May; 36(4):340-51. PMID: 22539395; PMCID: PMC3387741.
      Citations: 58     Fields:    Translation:HumansCells
    89. Folsom Group. Communities of solution: the Folsom Report revisited. Ann Fam Med. 2012 May-Jun; 10(3):250-60. PMID: 22585890; PMCID: PMC3354975.
      Citations: 27     Fields:    Translation:Humans
    90. MacKillop J, Amlung MT, Wier LM, David SP, Ray LA, Bickel WK, Sweet LH. The neuroeconomics of nicotine dependence: a preliminary functional magnetic resonance imaging study of delay discounting of monetary and cigarette rewards in smokers. Psychiatry Res. 2012 Apr 30; 202(1):20-9. PMID: 22633679; PMCID: PMC3530421.
      Citations: 35     Fields:    Translation:Humans
    91. Liu T, David SP, Tyndale RF, Wang H, Yu XQ, Chen W, Zhou Q, Chen WQ. Relationship between amounts of daily cigarette consumption and abdominal obesity moderated by CYP2A6 genotypes in Chinese male current smokers. Ann Behav Med. 2012 Apr; 43(2):253-61. PMID: 22160797; PMCID: PMC4114962.
      Citations: 7     Fields:    Translation:Humans
    92. Liu T, Tyndale RF, David SP, Wang H, Yu XQ, Chen W, Wen XZ, Chen WQ. Association between daily cigarette consumption and hypertension moderated by CYP2A6 genotypes in Chinese male current smokers. J Hum Hypertens. 2013 Jan; 27(1):24-30. PMID: 22217675; PMCID: PMC4128783.
      Citations: 6     Fields:    Translation:Humans
    93. Bergen AW, Mallick A, Nishita D, Wei X, Michel M, Wacholder A, David SP, Swan GE, Reid MW, Simons A, Andrews JA. Chronic psychosocial stressors and salivary biomarkers in emerging adults. Psychoneuroendocrinology. 2012 Aug; 37(8):1158-70. PMID: 22172638; PMCID: PMC3774595.
      Citations: 3     Fields:    Translation:Humans
    94. Liu T, Chen WQ, David SP, Tyndale RF, Wang H, Chen YM, Yu XQ, Chen W, Zhou Q, Ling WH. Interaction between heavy smoking and CYP2A6 genotypes on type 2 diabetes and its possible pathways. Eur J Endocrinol. 2011 Dec; 165(6):961-7. PMID: 21964962; PMCID: PMC4112659.
      Citations: 10     Fields:    Translation:HumansCells
    95. Dewey FE, Chen R, Cordero SP, Ormond KE, Caleshu C, Karczewski KJ, Whirl-Carrillo M, Wheeler MT, Dudley JT, Byrnes JK, Cornejo OE, Knowles JW, Woon M, Sangkuhl K, Gong L, Thorn CF, Hebert JM, Capriotti E, David SP, Pavlovic A, West A, Thakuria JV, Ball MP, Zaranek AW, Rehm HL, Church GM, West JS, Bustamante CD, Snyder M, Altman RB, Klein TE, Butte AJ, Ashley EA. Phased whole-genome genetic risk in a family quartet using a major allele reference sequence. PLoS Genet. 2011 Sep; 7(9):e1002280. PMID: 21935354; PMCID: PMC3174201.
      Citations: 85     Fields:    Translation:HumansCells
    96. Janes AC, Smoller JW, David SP, Frederick BD, Haddad S, Basu A, Fava M, Evins AE, Kaufman MJ. Association between CHRNA5 genetic variation at rs16969968 and brain reactivity to smoking images in nicotine dependent women. Drug Alcohol Depend. 2012 Jan 01; 120(1-3):7-13. PMID: 21764527; PMCID: PMC3203995.
      Citations: 23     Fields:    Translation:Humans
    97. Liu T, David SP, Tyndale RF, Wang H, Zhou Q, Ding P, He YH, Yu XQ, Chen W, Crump C, Wen XZ, Chen WQ. Associations of CYP2A6 genotype with smoking behaviors in southern China. Addiction. 2011 May; 106(5):985-94. PMID: 21205058; PMCID: PMC3074015.
      Citations: 32     Fields:    Translation:Humans
    98. David SP, Rees HS, MacManus MP. Use of prechemotherapy positron emission tomography-CT imaging, acquired in the treatment position, to help plan involved nodal radiotherapy for a patient with diffuse large B-cell lymphoma. J Med Imaging Radiat Oncol. 2011 Apr; 55(2):236-41. PMID: 21501416.
      Citations: 1     Fields:    Translation:Humans
    99. David SP, Johnstone EC, Churchman M, Aveyard P, Murphy MF, Munafò MR. Pharmacogenetics of smoking cessation in general practice: results from the patch II and patch in practice trials. Nicotine Tob Res. 2011 Mar; 13(3):157-67. PMID: 21330274; PMCID: PMC3107615.
      Citations: 14     Fields:    Translation:Humans
    100. Leventhal AM, David SP, Brightman M, Strong D, McGeary JE, Brown RA, Lloyd-Richardson EE, Uhl GR, Niaura R, Munafò M. Dopamine D4 receptor gene variation moderates the efficacy of bupropion for smoking cessation. Pharmacogenomics J. 2012 Feb; 12(1):86-92. PMID: 20661272; PMCID: PMC2981689.
      Citations: 22     Fields:    Translation:Humans
    101. Sweet LH, Mulligan RC, Finnerty CE, Jerskey BA, David SP, Cohen RA, Niaura RS. Effects of nicotine withdrawal on verbal working memory and associated brain response. Psychiatry Res. 2010 Jul 30; 183(1):69-74. PMID: 20570495; PMCID: PMC2913712.
      Citations: 20     Fields:    Translation:Humans
    102. Uhl GR, Drgon T, Johnson C, Walther D, David SP, Aveyard P, Murphy M, Johnstone EC, Munafò MR. Genome-wide association for smoking cessation success: participants in the Patch in Practice trial of nicotine replacement. Pharmacogenomics. 2010 Mar; 11(3):357-67. PMID: 20235792; PMCID: PMC3040594.
      Citations: 31     Fields:    Translation:HumansCTClinical Trials
    103. David SP, Mezuk B, Zandi PP, Strong D, Anthony JC, Niaura R, Uhl GR, Eaton WW. Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans. Nicotine Tob Res. 2010 Mar; 12(3):251-62. PMID: 20133381; PMCID: PMC2825103.
      Citations: 10     Fields:    Translation:Humans
    104. Timpson NJ, David SP, Ebrahim S, Lawlor DA, Munafò MR. Association of the DRD2 gene Taq1A polymorphism and smoking behavior: a meta-analysis and new data. Nicotine Tob Res. 2009 Jan; 11(1):64-76. PMID: 19246443; PMCID: PMC3203402.
      Citations: 39     Fields:    Translation:Humans
    105. Koplan KE, David SP, Rigotti NA. [Smoking cessation]. Praxis (Bern 1994). 2008 Nov 05; 97(22):1185-6. PMID: 18979437.
      Citations:    Fields:    Translation:Humans
    106. David SP, Munafò MR. Genetic variation in the dopamine pathway and smoking cessation. Pharmacogenomics. 2008 Sep; 9(9):1307-21. PMID: 18781857.
      Citations: 16     Fields:    Translation:HumansCells
    107. David SP, Johnstone EC, Murphy MF, Aveyard P, Guo B, Lerman C, Munafò MR. Genetic variation in the serotonin pathway and smoking cessation with nicotine replacement therapy: new data from the Patch in Practice trial and pooled analyses. Drug Alcohol Depend. 2008 Nov 01; 98(1-2):77-85. PMID: 18562131; PMCID: PMC4439462.
      Citations: 13     Fields:    Translation:Humans
    108. Uhl GR, Liu QR, Drgon T, Johnson C, Walther D, Rose JE, David SP, Niaura R, Lerman C. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. Arch Gen Psychiatry. 2008 Jun; 65(6):683-93. PMID: 18519826; PMCID: PMC2430596.
      Citations: 148     Fields:    Translation:Humans
    109. David SP, Munafò MR. Smoking cessation in primary care. BMJ. 2008 May 31; 336(7655):1200-1. PMID: 18441374; PMCID: PMC2405833.
      Citations:    Fields:    
    110. Koplan KE, David SP, Rigotti NA. Smoking cessation. BMJ. 2008 Jan 26; 336(7637):217. PMID: 18219045; PMCID: PMC2213872.
      Citations: 2     Fields:    Translation:Humans
    111. Welton NJ, Johnstone EC, David SP, Munafò MR. A cost-effectiveness analysis of genetic testing of the DRD2 Taq1A polymorphism to aid treatment choice for smoking cessation. Nicotine Tob Res. 2008 Jan; 10(1):231-40. PMID: 18188764; PMCID: PMC2257987.
      Citations: 11     Fields:    Translation:Humans
    112. Paul RH, Grieve SM, Niaura R, David SP, Laidlaw DH, Cohen R, Sweet L, Taylor G, Clark RC, Pogun S, Gordon E. Chronic cigarette smoking and the microstructural integrity of white matter in healthy adults: a diffusion tensor imaging study. Nicotine Tob Res. 2008 Jan; 10(1):137-47. PMID: 18188754; PMCID: PMC2276564.
      Citations: 60     Fields:    Translation:Humans
    113. David SP, Strong DR, Brown RA, Lloyd-Richardson EE, Wileyto PE, Evins AE, Shields PG, Lerman C, Niaura R, Munafò MR. Bupropion efficacy for smoking cessation is influenced by the DRD2 Taq1A polymorphism: analysis of pooled data from two clinical trials. Nicotine Tob Res. 2007 12; 9(12):1251-7. PMID: 18058343; PMCID: PMC2128730.
      Citations: 43     Fields:    Translation:Humans
    114. David SP, Johansen-Berg H, Mackillop J, Sweet LH, Cohen RA, Niaura R, Rogers RD, Matthews PM, Walton RT, Munafò MR. Effects of Acute Nicotine Abstinence on Cue-elicited Ventral Striatum/Nucleus Accumbens Activation in Female Cigarette Smokers: A Functional Magnetic Resonance Imaging Study. Brain Imaging Behav. 2007 Dec; 1(3-4):43-57. PMID: 18458752; PMCID: PMC2367252.
      Citations: 31     Fields:    
    115. David SP, Brown RA, Papandonatos GD, Kahler CW, Lloyd-Richardson EE, Shields PG, Lerman C, Strong D, McCaffery J, Niaura R, Munafò MR. Pharmacogenetic clinical trial of sustained-release bupropion for smoking cessation. Nicotine Tob Res. 2007 Aug; 9(8):821-33. PMID: 17654295; PMCID: PMC2039873.
      Citations: 47     Fields:    Translation:Humans
    116. David SP, Smith M, Lee CS, Sullivan G. Successful Latino community partnership program for smoking cessation. Am J Public Health. 2007 Aug; 97(8):1348-9; author reply 1349. PMID: 17600240; PMCID: PMC1931457.
      Citations:    Fields:    Translation:Humans
    117. Johnstone EC, Elliot KM, David SP, Murphy MF, Walton RT, Munafò MR. Association of COMT Val108/158Met genotype with smoking cessation in a nicotine replacement therapy randomized trial. Cancer Epidemiol Biomarkers Prev. 2007 Jun; 16(6):1065-9. PMID: 17548664; PMCID: PMC2031911.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    118. David SP, Murphy MF, Proctor M, Walton RT, Johnstone EC, Munafò MR. Genetic variation in the dopamine D4 receptor (DRD4) gene and smoking cessation: follow-up of a randomised clinical trial of transdermal nicotine patch. Pharmacogenomics J. 2008 Apr; 8(2):122-8. PMID: 17387332; PMCID: PMC2288552.
      Citations: 35     Fields:    Translation:HumansCells
    119. David SP, Murphy MF, Walton RT, Johnstone EC, Munafò MR. The serotonin transporter 5-HTTLPR polymorphism and treatment response to nicotine patch: follow-up of a randomized controlled trial. Nicotine Tob Res. 2007 Feb; 9(2):225-31. PMID: 17365753; PMCID: PMC2031912.
      Citations: 22     Fields:    Translation:Humans
    120. David SP, Eaton CB, Culpepper L, Goldman RE, Lavallee LK, Simmons EM. Building a successful research enterprise in family medicine: the Brown experience. Med Health R I. 2006 Aug; 89(8):281-4. PMID: 16967659; PMCID: PMC1992529.
      Citations:    Fields:    Translation:Humans
    121. Long R, David SP, Monroe A, Shaw J. Fellowship training in family medicine at Brown: adding depth to breadth. Med Health R I. 2006 Aug; 89(8):274-5. PMID: 16967657.
      Citations:    Fields:    Translation:Humans
    122. David SP, Johansen-Berg H, Smith SM, Rogers RD, Matthews PM, Walton RT, Munafò MR. Ventral striatum/nucleus accumbens activation to smoking-related pictorial cues in smokers and nonsmokers: a functional magnetic resonance imaging study. Biol Psychiatry. 2005 Sep 15; 58(6):488-94. PMID: 16023086; PMCID: PMC4439461.
      Citations: 146     Fields:    Translation:Humans
    123. David SP, Murthy NV, Rabiner EA, Johnstone EC, Jacob R, Walton RT, Grasby PM, Munafó MR. A functional genetic variation of the serotonin (5-HT) transporter affects 5-HT1A receptor binding in humans. J Neurosci. 2005 Mar 09; 25(10):2586-90. PMID: 15758168; PMCID: PMC1942077.
      Citations: 105     Fields:    Translation:HumansCells
    124. David SP, Eaton CB, Taylor JS, Stamp MJ, Cyr M, Siegel B, Gramling R, Walton R. Envisaging and applying a unifying three-dimensional theoretical framework for generalist physicians. Med Health R I. 2004 Nov; 87(11):336-40. PMID: 15631301.
      Citations:    Fields:    Translation:Humans
    125. Gramling R, Duffy C, David S. Does providing hereditary breast cancer risk assessment support to practicing physicians decrease the likelihood of them discussing such risk with their patients? Genet Med. 2004 Nov-Dec; 6(6):542. PMID: 15545753.
      Citations:    Fields:    Translation:Humans
    126. Bradburn M, Bowes L, David S, Munafò M. Are there sex differences in transdermal nicotine replacement therapy patch efficacy? A meta-analysis. Nicotine Tob Res. 2004 Oct; 6(5):769-76. PMID: 15700912.
      Citations: 21     Fields:    Translation:Humans
    127. David SP. Pharmacogenetics. Prim Care. 2004 Sep; 31(3):543-59, ix. PMID: 15331247.
      Citations: 1     Fields:    
    128. David SP, Niaura R, Papandonatos GD, Shadel WG, Burkholder GJ, Britt DM, Day A, Stumpff J, Hutchison K, Murphy M, Johnstone E, Walton RT, Griffiths SE. Does the DRD2-Taq1 A polymorphism influence treatment response to bupropion hydrochloride for reduction of the nicotine withdrawal syndrome? Nicotine Tob Res. 2003 Dec; 5(6):935-42. PMID: 14668077.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    129. David SP. Should we offer routine breast cancer screening with mammography? Am Fam Physician. 2003 Jul 15; 68(2):260-2. PMID: 12892345.
      Citations:    Fields:    Translation:HumansPHPublic Health
    130. Gramling R, David S. Genetic susceptibility to breast cancer: teaching points. Fam Med. 2003 Jul-Aug; 35(7):466-8. PMID: 12861454.
      Citations:    Fields:    Translation:Humans
    131. David SP, Eaton CB. Comment on "The public health implications of smoking-induced decreased serum and red blood cell folate levels". Nicotine Tob Res. 2003 Jun; 5(3):397-9. PMID: 12791535.
      Citations:    Fields:    Translation:HumansPHPublic Health
    132. Stamp MJ, David SP. Are family physicians willing to use pharmacogenetics for smoking cessation therapy? Fam Med. 2003 Feb; 35(2):83. PMID: 12607800.
      Citations: 1     Fields:    Translation:Humans
    133. David SP, David SP. Should we prescribe antibiotics for acute conjunctivitis? Am Fam Physician. 2002 Nov 01; 66(9):1649-50. PMID: 12449262.
      Citations:    Fields:    Translation:Humans
    134. David SP. Should we use multiple risk factor interventions for the primary prevention of coronary heart disease? Am Fam Physician. 2002 Jul 15; 66(2):245-6. PMID: 12152959.
      Citations: 1     Fields:    Translation:Humans
    135. David SP, Johnstone E, Murphy M, Yudkin P, Mant D, Walton R, Griffiths SE. No association between functional catechol O-methyl transferase 1947A>G polymorphism and smoking initiation, persistent smoking or smoking cessation. Pharmacogenetics. 2002 Apr; 12(3):265-8. PMID: 11927842.
      Citations: 22     Fields:    Translation:Humans
    136. David SP. Should we recommend nicotine replacement therapy? Am Fam Physician. 2001 Jun 01; 63(11):2245-7. PMID: 11417777.
      Citations:    Fields:    Translation:Humans
    137. David SP, Greer DS. Social marketing: application to medical education. Ann Intern Med. 2001 Jan 16; 134(2):125-7. PMID: 11177316.
      Citations: 5     Fields:    Translation:Humans
    138. David SP, David SP. Media advocacy for the office-based teacher of family medicine. Fam Med. 2001 Jan; 33(1):16-8. PMID: 11199903.
      Citations:    Fields:    Translation:Humans
    139. David SP. Reflections from a rotation in Cambridge, England. Fam Med. 2000 May; 32(5):310-2. PMID: 10820671.
      Citations:    Fields:    Translation:Humans
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