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Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis.
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Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis.
Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosis. Proc Natl Acad Sci U S A. 2008 Jun 17; 105(24):8452-7.
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PubMed
subject areas
Animals
Apoptosis
Carboxypeptidase H
Cell Survival
Cells, Cultured
Diabetes Mellitus, Type 2
Endoplasmic Reticulum
Golgi Apparatus
Humans
Hyperglycemia
Hyperinsulinism
Insulin-Secreting Cells
Mice
Mice, Mutant Strains
Palmitates
Proteome
authors with profiles
Kenneth S. Polonsky