A condition characterized by persistent spasms (SPASM) involving multiple muscles, primarily in the lower limbs and trunk. The illness tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that become continuous. Minor sensory stimuli, such as noise and light touch, precipitate severe spasms. Spasms do not occur during sleep and only rarely involve cranial muscles. Respiration may become impaired in advanced cases. (Adams et al., Principles of Neurology, 6th ed, p1492; Neurology 1998 Jul;51(1):85-93)

Descriptor ID	D016750
MeSH Number(s)	C10.114.812 C10.228.854.790 C10.668.900 C20.111.258.850
Concept/Terms	Stiff-Person Syndrome Stiff-Person Syndrome Stiff Person Syndrome Syndrome, Stiff-Person Stiff-Man Syndrome Stiff Man Syndrome Syndrome, Stiff-Man Stiffman Syndrome Syndrome, Stiffman Stiff-Baby Syndrome Stiff-Baby Syndromes Syndrome, Stiff-Baby Syndromes, Stiff-Baby Congenital Stiff-Man Syndrome Congenital Stiff Man Syndrome Congenital Stiff-Man Syndromes Stiff-Man Syndrome, Congenital Stiff-Man Syndromes, Congenital Syndrome, Congenital Stiff-Man Syndromes, Congenital Stiff-Man Congenital Stiff-Person Syndrome Congenital Stiff-Person Syndromes Stiff-Person Syndrome, Congenital Stiff-Person Syndromes, Congenital Syndrome, Congenital Stiff-Person Syndromes, Congenital Stiff-Person Startle Syndrome Startle Syndromes Syndrome, Startle Syndromes, Startle Moersch-Woltmann Syndrome Moersch Woltmann Syndrome Syndrome, Moersch-Woltmann Stiff-Trunk Syndrome Stiff Trunk Syndrome Stiff-Trunk Syndromes Syndrome, Stiff-Trunk Syndromes, Stiff-Trunk Familial Hyperekplexia Familial Hyperekplexia Familial Hyperekplexias Hyperekplexia, Familial Hyperekplexias, Familial Hereditary Hyperekplexia Hereditary Hyperekplexia Hereditary Hyperekplexias Hyperekplexia, Hereditary Hyperekplexias, Hereditary

Below are MeSH descriptors whose meaning is more general than "Stiff-Person Syndrome".

Below are MeSH descriptors whose meaning is related to "Stiff-Person Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Stiff-Person Syndrome".