Malformations of Cortical Development
"Malformations of Cortical Development" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Abnormalities in the development of the CEREBRAL CORTEX. These include malformations arising from abnormal neuronal and glial CELL PROLIFERATION or APOPTOSIS (Group I); abnormal neuronal migration (Group II); and abnormal establishment of cortical organization (Group III). Many INBORN METABOLIC BRAIN DISORDERS affecting CNS formation are often associated with cortical malformations. They are common causes of EPILEPSY and developmental delay.
| Descriptor ID |
D054220
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| MeSH Number(s) |
C10.500.507 C16.131.666.507
|
| Concept/Terms |
Malformations of Cortical Development- Malformations of Cortical Development
- Cortical Development Malformation
- Cortical Development Malformations
- Development Malformation, Cortical
- Development Malformations, Cortical
- Malformations of Cerebral Cortex Development
Cortical Dysplasia- Cortical Dysplasia
- Cortical Dysplasias
- Dysplasia, Cortical
- Dysplasias, Cortical
- Cortical Dysplasia, Cerebral
- Cerebral Cortical Dysplasias
- Cortical Dysplasias, Cerebral
- Dysplasia, Cerebral Cortical
- Dysplasias, Cerebral Cortical
- Cerebral Cortical Dysplasia
|
Below are MeSH descriptors whose meaning is more general than "Malformations of Cortical Development".
Below are MeSH descriptors whose meaning is more specific than "Malformations of Cortical Development".
This graph shows the total number of publications written about "Malformations of Cortical Development" by people in this website by year, and whether "Malformations of Cortical Development" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2008 | 4 | 1 | 5 |
| 2009 | 1 | 0 | 1 |
| 2010 | 3 | 0 | 3 |
| 2011 | 2 | 0 | 2 |
| 2012 | 3 | 1 | 4 |
| 2013 | 2 | 0 | 2 |
| 2014 | 3 | 1 | 4 |
| 2015 | 5 | 0 | 5 |
| 2016 | 3 | 0 | 3 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Malformations of Cortical Development" by people in Profiles.
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Profiling PI3K-AKT-MTOR variants in focal brain malformations reveals new insights for diagnostic care. Brain. 2022 04 29; 145(3):925-938.
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International consensus recommendations on the diagnostic work-up for malformations of cortical development. Nat Rev Neurol. 2020 11; 16(11):618-635.
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Bilateral polymicrogyria associated with dystonia: A new neurogenetic syndrome? Am J Med Genet A. 2020 10; 182(10):2207-2213.
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Duplication 2p16 is associated with perisylvian polymicrogyria. Am J Med Genet A. 2019 12; 179(12):2343-2356.
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Heterogeneous clinical phenotypes and cerebral malformations reflected by rotatin cellular dynamics. Brain. 2019 04 01; 142(4):867-884.
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Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations. Neuron. 2018 12 19; 100(6):1354-1368.e5.
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Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery. N Engl J Med. 2017 10 26; 377(17):1648-1656.
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Focal cortical malformations in children with early infantile epilepsy and PCDH19 mutations: case report. Dev Med Child Neurol. 2018 01; 60(1):100-105.
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Recurrent de novo BICD2 mutation associated with arthrogryposis multiplex congenita and bilateral perisylvian polymicrogyria. Neuromuscul Disord. 2016 11; 26(11):744-748.
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Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism. JAMA Neurol. 2016 07 01; 73(7):836-845.