"Frameshifting, Ribosomal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A directed change in translational READING FRAMES that allows the production of a single protein from two or more OVERLAPPING GENES. The process is programmed by the nucleotide sequence of the MRNA and is sometimes also affected by the secondary or tertiary mRNA structure. It has been described mainly in VIRUSES (especially RETROVIRUSES); RETROTRANSPOSONS; and bacterial insertion elements but also in some cellular genes.
| Descriptor ID |
D018965
|
| MeSH Number(s) |
G02.111.660.871.200 G03.734.871.200 G05.308.215
|
| Concept/Terms |
Frameshifting, Ribosomal- Frameshifting, Ribosomal
- Ribosomal Frame Shift
- Frame Shift, Ribosomal
- Frame Shifts, Ribosomal
- Ribosomal Frame Shifts
- Frameshifting, Translational
- Translational Frameshifting
- Ribosomal Frameshifting
- Ribosomal Frameshift
- Frameshift, Ribosomal
- Frameshifts, Ribosomal
- Ribosomal Frameshifts
- Ribosomal Frame Shifting
- Frame Shifting, Ribosomal
|
Below are MeSH descriptors whose meaning is more general than "Frameshifting, Ribosomal".
Below are MeSH descriptors whose meaning is more specific than "Frameshifting, Ribosomal".
This graph shows the total number of publications written about "Frameshifting, Ribosomal" by people in this website by year, and whether "Frameshifting, Ribosomal" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Frameshifting, Ribosomal" by people in Profiles.
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The SARS-CoV-2 Programmed -1 Ribosomal Frameshifting Element Crystal Structure Solved to 2.09 Å Using Chaperone-Assisted RNA Crystallography. ACS Chem Biol. 2021 08 20; 16(8):1469-1481.
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A frameshifting stimulatory stem loop destabilizes the hybrid state and impedes ribosomal translocation. Proc Natl Acad Sci U S A. 2014 Apr 15; 111(15):5538-43.
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Adaptive translation as a mechanism of stress response and adaptation. Annu Rev Genet. 2013; 47:121-37.
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Alternative translational reading frames as a novel source of epitopes for an expanded CD8 T-cell repertoire: use of a retroviral system to assess the translational requirements for CTL recognition and lysis. Viral Immunol. 2010 Dec; 23(6):577-83.
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The MC-Fold and MC-Sym pipeline infers RNA structure from sequence data. Nature. 2008 Mar 06; 452(7183):51-5.