Caspase 7
"Caspase 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 3 and CASPASE 10. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
Descriptor ID |
D053179
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MeSH Number(s) |
D08.811.277.656.262.500.126.350.700 D08.811.277.656.300.200.126.350.700 D12.644.360.075.405.350.700 D12.776.476.075.405.350.700
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Concept/Terms |
Caspase 7- Caspase 7
- Mch-3 Protease
- Mch 3 Protease
- Protease, Mch-3
- Apoptotic Protease Mch-3
- Apoptotic Protease Mch 3
- Mch-3, Apoptotic Protease
- Protease Mch-3, Apoptotic
- Caspase-7
- ICE-Like Apoptotic Protease 3
- ICE Like Apoptotic Protease 3
Procaspase 7- Procaspase 7
- Pro-caspase 7
- Pro caspase 7
- Pro-caspase-7
- Procaspase-7
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Below are MeSH descriptors whose meaning is more general than "Caspase 7".
Below are MeSH descriptors whose meaning is more specific than "Caspase 7".
This graph shows the total number of publications written about "Caspase 7" by people in this website by year, and whether "Caspase 7" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 | 1997 | 0 | 1 | 1 | 1998 | 0 | 1 | 1 | 2003 | 0 | 1 | 1 | 2005 | 0 | 1 | 1 | 2007 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2013 | 1 | 3 | 4 | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Caspase 7" by people in Profiles.
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Shigemura M, Lecuona E, Angulo M, Homma T, RodrÃguez DA, Gonzalez-Gonzalez FJ, Welch LC, Amarelle L, Kim SJ, Kaminski N, Budinger GRS, Solway J, Sznajder JI. Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling. Sci Transl Med. 2018 09 05; 10(457).
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Brickley DR, Agyeman AS, Kopp RF, Hall BA, Harbeck MC, Belova L, Volden PA, Wu W, Roe MW, Conzen SD. Serum- and glucocorticoid-induced protein kinase 1 (SGK1) is regulated by store-operated Ca2+ entry and mediates cytoprotection against necrotic cell death. J Biol Chem. 2013 Nov 08; 288(45):32708-19.
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Zhu H, Pytel P, Gomez CM. Selective inhibition of caspases in skeletal muscle reverses the apoptotic synaptic degeneration in slow-channel myasthenic syndrome. Hum Mol Genet. 2014 Jan 01; 23(1):69-77.
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Edwards AL, Gavathiotis E, LaBelle JL, Braun CR, Opoku-Nsiah KA, Bird GH, Walensky LD. Multimodal interaction with BCL-2 family proteins underlies the proapoptotic activity of PUMA BH3. Chem Biol. 2013 Jul 25; 20(7):888-902.
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Doherty KR, Wappel RL, Talbert DR, Trusk PB, Moran DM, Kramer JW, Brown AM, Shell SA, Bacus S. Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes. Toxicol Appl Pharmacol. 2013 Oct 01; 272(1):245-55.
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King LA, Schwartz NB, Domowicz MS. Glial migratory streams in the developing hindbrain: a slice culture approach. J Neurosci Methods. 2009 Feb 15; 177(1):30-43.
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Tong WG, Ding XZ, Talamonti MS, Bell RH, Adrian TE. Leukotriene B4 receptor antagonist LY293111 induces S-phase cell cycle arrest and apoptosis in human pancreatic cancer cells. Anticancer Drugs. 2007 Jun; 18(5):535-41.
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Ding X, Xu F, Chen H, Tesh RB, Xiao SY. Apoptosis of hepatocytes caused by Punta Toro virus (Bunyaviridae: Phlebovirus) and its implication for Phlebovirus pathogenesis. Am J Pathol. 2005 Oct; 167(4):1043-9.
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Cowan KN, Leung WC, Mar C, Bhattacharjee R, Zhu Y, Rabinovitch M. Caspases from apoptotic myocytes degrade extracellular matrix: a novel remodeling paradigm. FASEB J. 2005 Nov; 19(13):1848-50.
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Metkar SS, Wang B, Ebbs ML, Kim JH, Lee YJ, Raja SM, Froelich CJ. Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis. J Cell Biol. 2003 Mar 17; 160(6):875-85.
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