Guanine Nucleotide-Releasing Factor 2
"Guanine Nucleotide-Releasing Factor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 145-kDa guanine nucleotide exchange factor that is specific for rap1 and ras GTP-BINDING PROTEINS. It associates with SH3 domains of the crk family of signaling proteins.
Below are MeSH descriptors whose meaning is more general than "Guanine Nucleotide-Releasing Factor 2".
Below are MeSH descriptors whose meaning is more specific than "Guanine Nucleotide-Releasing Factor 2".
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Below are the most recent publications written about "Guanine Nucleotide-Releasing Factor 2" by people in Profiles.
Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons. Curr Biol. 2004 Apr 06; 14(7):606-10.
The CrkL adapter protein is required for type I interferon-dependent gene transcription and activation of the small G-protein Rap1. Biochem Biophys Res Commun. 2002 Mar 08; 291(4):744-50.