Guanine Nucleotide-Releasing Factor 2
"Guanine Nucleotide-Releasing Factor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 145-kDa guanine nucleotide exchange factor that is specific for rap1 and ras GTP-BINDING PROTEINS. It associates with SH3 domains of the crk family of signaling proteins.
| Descriptor ID |
D020735
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| MeSH Number(s) |
D12.644.360.325.300.300 D12.776.476.325.300.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Guanine Nucleotide-Releasing Factor 2".
Below are MeSH descriptors whose meaning is more specific than "Guanine Nucleotide-Releasing Factor 2".
This graph shows the total number of publications written about "Guanine Nucleotide-Releasing Factor 2" by people in this website by year, and whether "Guanine Nucleotide-Releasing Factor 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Guanine Nucleotide-Releasing Factor 2" by people in Profiles.
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Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons. Curr Biol. 2004 Apr 06; 14(7):606-10.
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The CrkL adapter protein is required for type I interferon-dependent gene transcription and activation of the small G-protein Rap1. Biochem Biophys Res Commun. 2002 Mar 08; 291(4):744-50.