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A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation.
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A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation.
A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation. Nat Commun. 2021 10 15; 12(1):6025.
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PubMed
subject areas
Alanine
Amyotrophic Lateral Sclerosis
Animals
Arginine
C9orf72 Protein
Caenorhabditis elegans
Dipeptides
Female
Frontotemporal Dementia
Gene Editing
Gene Knockdown Techniques
Glycine
HEK293 Cells
Humans
Middle Aged
Motor Neurons
Nerve Degeneration
Proline
authors with profiles
Ghanashyam Ghadge
Yoshifumi Sonobe
Raymond P. Roos
Paschalis Kratsios