"Nerve Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Descriptor ID |
D009410
|
| MeSH Number(s) |
C23.550.737
|
| Concept/Terms |
Nerve Degeneration- Nerve Degeneration
- Degeneration, Nerve
- Degenerations, Nerve
- Nerve Degenerations
- Neuron Degeneration
- Degeneration, Neuron
- Degenerations, Neuron
- Neuron Degenerations
|
Below are MeSH descriptors whose meaning is more general than "Nerve Degeneration".
Below are MeSH descriptors whose meaning is more specific than "Nerve Degeneration".
This graph shows the total number of publications written about "Nerve Degeneration" by people in this website by year, and whether "Nerve Degeneration" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 2 | 3 |
| 1995 | 2 | 0 | 2 |
| 1996 | 1 | 1 | 2 |
| 1997 | 2 | 3 | 5 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 4 | 4 |
| 2002 | 2 | 0 | 2 |
| 2003 | 2 | 0 | 2 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 0 | 1 |
| 2007 | 3 | 0 | 3 |
| 2008 | 5 | 3 | 8 |
| 2009 | 0 | 2 | 2 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 1 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 3 | 1 | 4 |
| 2018 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nerve Degeneration" by people in Profiles.
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A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation. Nat Commun. 2021 10 15; 12(1):6025.
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Accumulation of neurofibrillary tangles and activated microglia is associated with lower neuron densities in the aphasic variant of Alzheimer's disease. Brain Pathol. 2021 01; 31(1):189-204.
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Lipidomic Analysis of a-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. Mol Cell. 2019 03 07; 73(5):1001-1014.e8.
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Pathophysiological relevance of deiodinase polymorphism. Curr Opin Endocrinol Diabetes Obes. 2018 10; 25(5):341-346.
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Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression. Hum Mol Genet. 2015 Sep 15; 24(18):5299-312.
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The Spontaneous Ataxic Mouse Mutant Tippy is Characterized by a Novel Purkinje Cell Morphogenesis and Degeneration Phenotype. Cerebellum. 2015 Jun; 14(3):292-307.
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DnaJ-1 and karyopherin a3 suppress degeneration in a new Drosophila model of Spinocerebellar Ataxia Type 6. Hum Mol Genet. 2015 Aug 01; 24(15):4385-96.
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A53T human a-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration. J Neurosci. 2015 Jan 21; 35(3):890-905.
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Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function. Cereb Cortex. 2015 Nov; 25(11):4259-72.
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FGF-2 released from degenerating neurons exerts microglial-induced neuroprotection via FGFR3-ERK signaling pathway. J Neuroinflammation. 2014 Apr 16; 11:76.