Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells.

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Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells.

Wu MH, Yan B, Humerickhouse R, Dolan ME. Irinotecan activation by human carboxylesterases in colorectal adenocarcinoma cells. Clin Cancer Res. 2002 Aug; 8(8):2696-700.

View in: PubMed

subject areas

Antineoplastic Agents, Phytogenic
Blotting, Western
Camptothecin
Carboxylic Ester Hydrolases
Cloning, Molecular
Colorectal Neoplasms
DNA, Complementary
Dose-Response Relationship, Drug
Electrophoresis, Polyacrylamide Gel
Enzyme Inhibitors
Gene Library
Humans
Hydrolysis
Isoelectric Focusing
Kinetics
Protein Isoforms
Time Factors
Transfection
Tumor Cells, Cultured

authors with profiles

Mary Eileen Dolan