Social isolation dysregulates endocrine and behavioral stress while increasing malignant burden of spontaneous mammary tumors.
Hermes GL, Delgado B, Tretiakova M, Cavigelli SA, Krausz T, Conzen SD, McClintock MK. Social isolation dysregulates endocrine and behavioral stress while increasing malignant burden of spontaneous mammary tumors. Proc Natl Acad Sci U S A. 2009 Dec 29; 106(52):22393-8.
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Animals
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Behavior, Animal
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Breast Neoplasms
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Carcinoma, Ductal, Breast
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Carcinoma, Intraductal, Noninfiltrating
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Corticosterone
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Endocrine Glands
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Female
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Humans
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Mammary Neoplasms, Experimental
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Ovary
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Rats
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Rats, Sprague-Dawley
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Receptors, Glucocorticoid
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Risk Factors
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Social Environment
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Social Isolation
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Stress, Physiological
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Stress, Psychological