"Isaacs Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rare neuromuscular disorder with onset usually in late childhood or early adulthood, characterized by intermittent or continuous widespread involuntary muscle contractions; FASCICULATION; hyporeflexia; MUSCLE CRAMP; MUSCLE WEAKNESS; HYPERHIDROSIS; TACHYCARDIA; and MYOKYMIA. Involvement of pharyngeal or laryngeal muscles may interfere with speech and breathing. The continuous motor activity persists during sleep and general anesthesia (distinguishing this condition from STIFF-PERSON SYNDROME). Familial and acquired (primarily autoimmune) forms have been reported. (From Ann NY Acad Sci 1998 May 13;841:482-496; Adams et al., Principles of Neurology, 6th ed, p1491)
Descriptor ID |
D020386
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MeSH Number(s) |
C05.651.392 C10.668.829.425
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Concept/Terms |
Isaacs Syndrome- Isaacs Syndrome
- Gamstorp-Wohlfart Syndrome
- Gamstorp Wohlfart Syndrome
- Gamstorp-Wohlfart Syndromes
- Syndromes, Gamstorp-Wohlfart
- Isaacs' Syndrome
- Isaac Syndrome
- Isaacs-Mertens Syndrome
- Isaacs Mertens Syndrome
- Syndromes, Isaacs-Mertens
- Myokymia, Myotonia, Muscle Wasting, And Hyperhidrosis
- Neuromyotonia
- Pseudomyotonia
- Pseudomyotonia Syndrome of Isaacs
- Isaacs Pseudomyotonia Syndrome
- Quantal Squander
- Syndrome of Continuous Muscle Activity
- Continuous Muscle Activity Syndrome
- Myokymia, Continuous
- Continuous Myokymia
- Continuous Myokymias
- Myokymias, Continuous
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Below are MeSH descriptors whose meaning is more general than "Isaacs Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Isaacs Syndrome".
This graph shows the total number of publications written about "Isaacs Syndrome" by people in this website by year, and whether "Isaacs Syndrome" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Isaacs Syndrome" by people in Profiles.
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Paraneoplastic nerve hyperexcitability. Neurol Res. 2015 Jun; 37(6):553-9.