"Succinate Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein containing oxidoreductase that catalyzes the dehydrogenation of SUCCINATE to fumarate. In most eukaryotic organisms this enzyme is a component of mitochondrial electron transport complex II.
| Descriptor ID |
D013385
|
| MeSH Number(s) |
D05.500.562.750.249.500 D08.811.600.250.500.750.500 D08.811.600.250.875.249.500 D08.811.682.660.385.500 D08.811.682.830.249.500 D12.776.157.427.374.375.909.500 D12.776.331.199.750.500 D12.776.543.277.500.750.500 D12.776.543.277.875.249.500 D12.776.556.579.374.375.141.500
|
| Concept/Terms |
Succinate Dehydrogenase- Succinate Dehydrogenase
- Dehydrogenase, Succinate
- Succinic Dehydrogenase
- Dehydrogenase, Succinic
- Succinic Oxidase
- Oxidase, Succinic
- Fumarate Reductase
- Reductase, Fumarate
|
Below are MeSH descriptors whose meaning is more general than "Succinate Dehydrogenase".
Below are MeSH descriptors whose meaning is more specific than "Succinate Dehydrogenase".
This graph shows the total number of publications written about "Succinate Dehydrogenase" by people in this website by year, and whether "Succinate Dehydrogenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Succinate Dehydrogenase" by people in Profiles.
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Bacteroides fragilis Maintains Concurrent Capability for Anaerobic and Nanaerobic Respiration. J Bacteriol. 2023 01 26; 205(1):e0038922.
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Paraganglioma of the Head and Neck: A Review. Endocr Pract. 2023 Feb; 29(2):141-147.
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Molecular Mechanism of the Association Between Atrial Fibrillation and Heart Failure Includes Energy Metabolic Dysregulation Due to Mitochondrial Dysfunction. J Card Fail. 2019 Nov; 25(11):911-920.
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Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation. Cell Metab. 2016 07 12; 24(1):158-66.
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Urinary Bladder Paragangliomas: How Immunohistochemistry Can Assist to Identify Patients With SDHB Germline and Somatic Mutations. Am J Surg Pathol. 2015 Nov; 39(11):1488-92.
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Association of urinary bladder paragangliomas with germline mutations in the SDHB and VHL genes. Urol Oncol. 2015 Apr; 33(4):167.e13-20.
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SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27; 50(6):919-30.
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Bilateral adrenal medullary hyperplasia associated with an SDHB mutation. J Clin Oncol. 2011 Mar 10; 29(8):e200-2.
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Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis. Mol Cell Biol. 2008 Jan; 28(2):718-31.
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Targeting nucleotide-requiring enzymes: implications for diazoxide-induced cardioprotection. Am J Physiol Heart Circ Physiol. 2003 Apr; 284(4):H1048-56.