 Chloride-Bicarbonate Antiporters
"Chloride-Bicarbonate Antiporters" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane proteins that allow the exchange of chloride ions for bicarbonate ions across the cellular membrane. The action of specific antiporters in this class serve important functions such as allowing the efficient exchange of bicarbonate across red blood cell membranes as they passage through capillaries and the reabsorption of bicarbonate ions by the kidney.
| Descriptor ID |
D027963
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| MeSH Number(s) |
D12.776.157.530.450.162.193 D12.776.543.550.190.276 D12.776.543.585.450.162.193
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| Concept/Terms |
Chloride-Bicarbonate Antiporters- Chloride-Bicarbonate Antiporters
- Antiporters, Chloride-Bicarbonate
- Chloride Bicarbonate Antiporters
- Cl- HCO3- Exchanger
- Chloride-Bicarbonate Exchangers
- Chloride Bicarbonate Exchangers
- Exchangers, Chloride-Bicarbonate
- Chloride-Bicarbonate Exchanger
- Chloride Bicarbonate Exchanger
- Exchanger, Chloride-Bicarbonate
- Cl(-)-HCO3(-)-Exchanger
- Bicarbonate-Chloride Antiport
- Antiport, Bicarbonate-Chloride
- Bicarbonate Chloride Antiport
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Below are MeSH descriptors whose meaning is more general than "Chloride-Bicarbonate Antiporters".
Below are MeSH descriptors whose meaning is more specific than "Chloride-Bicarbonate Antiporters".
This graph shows the total number of publications written about "Chloride-Bicarbonate Antiporters" by people in this website by year, and whether "Chloride-Bicarbonate Antiporters" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chloride-Bicarbonate Antiporters" by people in Profiles.
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Lan X, Pritchard JK. Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals. Science. 2016 May 20; 352(6288):1009-13.
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Kim KX, Sanneman JD, Kim HM, Harbidge DG, Xu J, Soleimani M, Wangemann P, Marcus DC. Slc26a7 chloride channel activity and localization in mouse Reissner's membrane epithelium. PLoS One. 2014; 9(5):e97191.
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Anbazhagan AN, Priyamvada S, Kumar A, Maher DB, Borthakur A, Alrefai WA, Malakooti J, Kwon JH, Dudeja PK. Translational repression of SLC26A3 by miR-494 in intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2014 Jan; 306(2):G123-31.
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Jacques T, Picard N, Miller RL, Riemondy KA, Houillier P, Sohet F, Ramakrishnan SK, Büsst CJ, Jayat M, Cornière N, Hassan H, Aronson PS, Hennings JC, Hübner CA, Nelson RD, Chambrey R, Eladari D. Overexpression of pendrin in intercalated cells produces chloride-sensitive hypertension. J Am Soc Nephrol. 2013 Jun; 24(7):1104-13.
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Chang EH, Lacruz RS, Bromage TG, Bringas P, Welsh MJ, Zabner J, Paine ML. Enamel pathology resulting from loss of function in the cystic fibrosis transmembrane conductance regulator in a porcine animal model. Cells Tissues Organs. 2011; 194(2-4):249-54.
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Schneider A, Larusch J, Sun X, Aloe A, Lamb J, Hawes R, Cotton P, Brand RE, Anderson MA, Money ME, Banks PA, Lewis MD, Baillie J, Sherman S, Disario J, Burton FR, Gardner TB, Amann ST, Gelrud A, George R, Rockacy MJ, Kassabian S, Martinson J, Slivka A, Yadav D, Oruc N, Barmada MM, Frizzell R, Whitcomb DC. Combined bicarbonate conductance-impairing variants in CFTR and SPINK1 variants are associated with chronic pancreatitis in patients without cystic fibrosis. Gastroenterology. 2011 Jan; 140(1):162-71.
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Leviel F, Hübner CA, Houillier P, Morla L, El Moghrabi S, Brideau G, Hassan H, Hatim H, Parker MD, Kurth I, Kougioumtzes A, Sinning A, Pech V, Riemondy KA, Miller RL, Hummler E, Shull GE, Aronson PS, Doucet A, Wall SM, Chambrey R, Eladari D. The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice. J Clin Invest. 2010 May; 120(5):1627-35.
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Asano K, Matsushita T, Umeno J, Hosono N, Takahashi A, Kawaguchi T, Matsumoto T, Matsui T, Kakuta Y, Kinouchi Y, Shimosegawa T, Hosokawa M, Arimura Y, Shinomura Y, Kiyohara Y, Tsunoda T, Kamatani N, Iida M, Nakamura Y, Kubo M. A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. Nat Genet. 2009 Dec; 41(12):1325-9.
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Lamprecht G, Hsieh CJ, Lissner S, Nold L, Heil A, Gaco V, Schäfer J, Turner JR, Gregor M. Intestinal anion exchanger down-regulated in adenoma (DRA) is inhibited by intracellular calcium. J Biol Chem. 2009 Jul 17; 284(29):19744-53.
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Lamprecht G, Gaco V, Turner JR, Natour D, Gregor M. Regulation of the intestinal anion exchanger DRA (downregulated in adenoma). Ann N Y Acad Sci. 2009 May; 1165:261-6.
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