Metalloproteases
"Metalloproteases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteases which use a metal, normally ZINC, in the catalytic mechanism. This group of enzymes is inactivated by metal CHELATORS.
Descriptor ID |
D045726
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MeSH Number(s) |
D08.811.277.656.675
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Metalloproteases".
Below are MeSH descriptors whose meaning is more specific than "Metalloproteases".
This graph shows the total number of publications written about "Metalloproteases" by people in this website by year, and whether "Metalloproteases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2007 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2009 | 1 | 0 | 1 | 2010 | 1 | 0 | 1 | 2012 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 | 2020 | 1 | 0 | 1 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Metalloproteases" by people in Profiles.
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Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ. Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition. Nat Commun. 2022 Apr 05; 13(1):1833.
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Liang WG, Mancl JM, Zhao M, Tang WJ. Structural analysis of Mycobacterium tuberculosis M13 metalloprotease Zmp1 open states. Structure. 2021 07 01; 29(7):709-720.e3.
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Herrou J, Choi VM, Bubeck Wardenburg J, Crosson S. Activation Mechanism of the Bacteroides fragilis Cysteine Peptidase, Fragipain. Biochemistry. 2016 07 26; 55(29):4077-84.
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Haass C, Kaether C, Thinakaran G, Sisodia S. Trafficking and proteolytic processing of APP. Cold Spring Harb Perspect Med. 2012 May; 2(5):a006270.
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Tonry JH, McNichol BA, Ramarao N, Chertow DS, Kim KS, Stibitz S, Schneewind O, Kashanchi F, Bailey CL, Popov S, Chung MC. Bacillus anthracis protease InhA regulates BslA-mediated adhesion in human endothelial cells. Cell Microbiol. 2012 Aug; 14(8):1219-30.
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Inoshima N, Wang Y, Bubeck Wardenburg J. Genetic requirement for ADAM10 in severe Staphylococcus aureus skin infection. J Invest Dermatol. 2012 May; 132(5):1513-6.
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Eckert MA, Yang J. Targeting invadopodia to block breast cancer metastasis. Oncotarget. 2011 Jul; 2(7):562-8.
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Phasukkijwatana N, Kunhapan B, Stankovich J, Chuenkongkaew WL, Thomson R, Thornton T, Bahlo M, Mushiroda T, Nakamura Y, Mahasirimongkol S, Tun AW, Srisawat C, Limwongse C, Peerapittayamongkol C, Sura T, Suthammarak W, Lertrit P. Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand. Hum Genet. 2010 Jul; 128(1):39-49.
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Han W, He YY. Requirement for metalloproteinase-dependent ERK and AKT activation in UVB-induced G1-S cell cycle progression of human keratinocytes. Photochem Photobiol. 2009 Jul-Aug; 85(4):997-1003.
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Kastrup CJ, Boedicker JQ, Pomerantsev AP, Moayeri M, Bian Y, Pompano RR, Kline TR, Sylvestre P, Shen F, Leppla SH, Tang WJ, Ismagilov RF. Spatial localization of bacteria controls coagulation of human blood by 'quorum acting'. Nat Chem Biol. 2008 Dec; 4(12):742-50.
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