"Metalloproteases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteases which use a metal, normally ZINC, in the catalytic mechanism. This group of enzymes is inactivated by metal CHELATORS.
| Descriptor ID |
D045726
|
| MeSH Number(s) |
D08.811.277.656.675
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Metalloproteases".
Below are MeSH descriptors whose meaning is more specific than "Metalloproteases".
This graph shows the total number of publications written about "Metalloproteases" by people in this website by year, and whether "Metalloproteases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Metalloproteases" by people in Profiles.
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Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition. Nat Commun. 2022 04 05; 13(1):1833.
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Structural analysis of Mycobacterium tuberculosis M13 metalloprotease Zmp1 open states. Structure. 2021 07 01; 29(7):709-720.e3.
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Activation Mechanism of the Bacteroides fragilis Cysteine Peptidase, Fragipain. Biochemistry. 2016 07 26; 55(29):4077-84.
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Trafficking and proteolytic processing of APP. Cold Spring Harb Perspect Med. 2012 May; 2(5):a006270.
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Bacillus anthracis protease InhA regulates BslA-mediated adhesion in human endothelial cells. Cell Microbiol. 2012 Aug; 14(8):1219-30.
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Genetic requirement for ADAM10 in severe Staphylococcus aureus skin infection. J Invest Dermatol. 2012 May; 132(5):1513-6.
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Targeting invadopodia to block breast cancer metastasis. Oncotarget. 2011 Jul; 2(7):562-8.
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Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand. Hum Genet. 2010 Jul; 128(1):39-49.
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Requirement for metalloproteinase-dependent ERK and AKT activation in UVB-induced G1-S cell cycle progression of human keratinocytes. Photochem Photobiol. 2009 Jul-Aug; 85(4):997-1003.
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Spatial localization of bacteria controls coagulation of human blood by 'quorum acting'. Nat Chem Biol. 2008 Dec; 4(12):742-50.