Mitogen-Activated Protein Kinase 7
"Mitogen-Activated Protein Kinase 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 110-kDa extracellular signal-regulated MAP kinase that is activated in response to cellular stress and by GROWTH FACTOR RECEPTORS-mediated pathways.
| Descriptor ID |
D048054
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.567.249.937 D12.644.360.450.169.937 D12.776.476.450.169.937
|
| Concept/Terms |
Mitogen-Activated Protein Kinase 7- Mitogen-Activated Protein Kinase 7
- Mitogen Activated Protein Kinase 7
- Extracellular Signal-Regulated Kinase 5
- Extracellular Signal Regulated Kinase 5
- MAPK7 Mitogen-Activated Protein Kinase
- MAPK7 Mitogen Activated Protein Kinase
- ERK5 Kinase
- Kinase, ERK5
- Big MAP Kinase 1
- BMK1 Kinase
- Kinase, BMK1
|
Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 7".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 7".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 7" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 7" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2012 | 3 | 0 | 3 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 7" by people in Profiles.
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Identification and characterization of fragment binding sites for allosteric ligand design using the site identification by ligand competitive saturation hotspots approach (SILCS-Hotspots). Biochim Biophys Acta Gen Subj. 2020 04; 1864(4):129519.
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Identification of Novel RAS Signaling Therapeutic Vulnerabilities in Diffuse Intrinsic Pontine Gliomas. Cancer Res. 2019 08 15; 79(16):4026-4041.
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A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis. Nat Commun. 2019 04 17; 10(1):1791.
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Disturbed flow-activated p90RSK kinase accelerates atherosclerosis by inhibiting SENP2 function. J Clin Invest. 2015 Mar 02; 125(3):1299-310.
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Tumor suppressors miR-143 and miR-145 and predicted target proteins API5, ERK5, K-RAS, and IRS-1 are differentially expressed in proximal and distal colon. Am J Physiol Gastrointest Liver Physiol. 2015 Feb 01; 308(3):G179-87.
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Granulocyte-colony stimulating factor attenuates oligomeric amyloid ß neurotoxicity by activation of neprilysin. PLoS One. 2014; 9(7):e103458.
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Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations. J Natl Cancer Inst. 2013 May 15; 105(10):733-42.
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De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis. Circ Res. 2013 Mar 15; 112(6):911-23.
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A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis. Circulation. 2013 Jan 29; 127(4):486-99.
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CHMP1A encodes an essential regulator of BMI1-INK4A in cerebellar development. Nat Genet. 2012 Nov; 44(11):1260-4.