"Glycocalyx" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The carbohydrate-rich zone on the cell surface. This zone can be visualized by a variety of stains as well as by its affinity for lectins. Although most of the carbohydrate is attached to intrinsic plasma membrane molecules, the glycocalyx usually also contains both glycoproteins and proteoglycans that have been secreted into the extracellular space and then adsorbed onto the cell surface. (Alberts et al., Molecular Biology of the Cell, 3d ed, p502)
| Descriptor ID |
D019276
|
| MeSH Number(s) |
A11.284.149.165.355
|
| Concept/Terms |
Glycocalyx- Glycocalyx
- Glycocalix
- Cell Coat
- Cell Coats
- Coat, Cell
- Coats, Cell
|
Below are MeSH descriptors whose meaning is more general than "Glycocalyx".
Below are MeSH descriptors whose meaning is more specific than "Glycocalyx".
This graph shows the total number of publications written about "Glycocalyx" by people in this website by year, and whether "Glycocalyx" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Glycocalyx" by people in Profiles.
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Hepatic conditioning results in better lung endothelial cell preservation under hypoxic environment in vitro. Int J Artif Organs. 2025 Feb; 48(2):84-91.
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Heparanase-induced endothelial glycocalyx degradation exacerbates lung ischemia/reperfusion injury in male mice. Physiol Rep. 2024 Oct; 12(20):e70113.
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Heparanase inhibition preserves the endothelial glycocalyx in lung grafts and improves lung preservation and transplant outcomes. Sci Rep. 2021 06 10; 11(1):12265.
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The cancer glycocalyx mechanically primes integrin-mediated growth and survival. Nature. 2014 Jul 17; 511(7509):319-25.
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Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritis. Kidney Int. 2014 Nov; 86(5):932-42.
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Characterization of an immunogenic glycocalyx on the surfaces of Cryptosporidium parvum oocysts and sporozoites. Infect Immun. 1999 Apr; 67(4):2022-4.