Primary Graft Dysfunction
"Primary Graft Dysfunction" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION.
| Descriptor ID |
D055031
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| MeSH Number(s) |
C14.907.725.675 C23.550.767.877.750
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Primary Graft Dysfunction".
Below are MeSH descriptors whose meaning is more specific than "Primary Graft Dysfunction".
This graph shows the total number of publications written about "Primary Graft Dysfunction" by people in this website by year, and whether "Primary Graft Dysfunction" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2011 | 3 | 2 | 5 |
| 2012 | 3 | 0 | 3 |
| 2013 | 2 | 0 | 2 |
| 2014 | 3 | 0 | 3 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 3 | 0 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Primary Graft Dysfunction" by people in Profiles.
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A successful heart and liver transplantation requiring intraoperative extracorporeal membrane oxygenation for primary cardiac allograft dysfunction in a patient with Fontan failure. J Card Surg. 2020 Jun; 35(6):1357-1359.
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Non-tuberculous mycobacteria in lung transplant recipients: Prevalence, risk factors, and impact on survival and chronic lung allograft dysfunction. Transpl Infect Dis. 2020 Apr; 22(2):e13229.
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Dectin-1 genetic deficiency predicts chronic lung allograft dysfunction and death. JCI Insight. 2019 11 14; 4(22).
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Quantitative Evidence for Revising the Definition of Primary Graft Dysfunction after Lung Transplant. Am J Respir Crit Care Med. 2018 01 15; 197(2):235-243.
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Clinical Risk Factors and Prognostic Model for Primary Graft Dysfunction after Lung Transplantation in Patients with Pulmonary Hypertension. Ann Am Thorac Soc. 2017 Oct; 14(10):1514-1522.
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Predictive model and risk factors associated with a revised definition of early allograft dysfunction in liver transplant recipients. Clin Transplant. 2017 Nov; 31(11).
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Report of the ISHLT Working Group on Primary Lung Graft Dysfunction, part I: Definition and grading-A 2016 Consensus Group statement of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2017 10; 36(10):1097-1103.
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An ISHLT consensus document for prevention and management strategies for mechanical circulatory support infection. J Heart Lung Transplant. 2017 10; 36(10):1137-1153.
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Lung Transplantation: The State of the Airways. Arch Pathol Lab Med. 2016 Mar; 140(3):241-4.
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The relationship between plasma lipid peroxidation products and primary graft dysfunction after lung transplantation is modified by donor smoking and reperfusion hyperoxia. J Heart Lung Transplant. 2016 Apr; 35(4):500-507.