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Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance.
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Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance.
Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance. Nat Cell Biol. 2022 02; 24(2):168-180.
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PubMed
subject areas
Actin-Related Protein 2-3 Complex
Actins
Animals
Antineoplastic Agents
Breast Neoplasms
Cell Line, Transformed
Cell Line, Tumor
Cell-Matrix Junctions
Drug Resistance, Neoplasm
Dynamins
Energy Metabolism
Extracellular Matrix
Female
Gene Expression Regulation, Neoplastic
Humans
Lung Neoplasms
Mechanotransduction, Cellular
Mice
Mice, Inbred BALB C
Microfilament Proteins
Mitochondria
Mitochondrial Dynamics
Mitochondrial Proteins
NF-E2-Related Factor 2
Nuclear Proteins
Oxidation-Reduction
Oxidative Stress
Peptide Elongation Factors
Tumor Microenvironment
authors with profiles
Stephen Archer