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Stephen Archer

TitleProfessor
InstitutionUniversity of Chicago
DepartmentMedicine
AddressChicago IL 60637
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    Collapse Research 
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    R01HL113003     (ARCHER, STEPHEN L)Apr 1, 2013 - Mar 31, 2018
    NIH
    The Role of DRP-1 and Mitochondrial Fission in Pulmonary Arterial Hypertension
    Role: Principal Investigator
    RC1HL099462     (ARCHER, STEPHEN L)Sep 30, 2009 - Aug 31, 2011
    NIH
    Impaired mitochondrial fusion in pulmonary arterial hypertension
    Role: Principal Investigator
    R01HL071115     (ARCHER, STEPHEN L)Jul 1, 2002 - Jan 31, 2017
    NIH
    O2 sensing in the human and rabbit ductus arteriosus.
    Role: Principal Investigator
    R29HL045735     (ARCHER, STEPHEN L)Aug 19, 1991 - Jul 31, 1996
    NIH
    EDRF IN NORMAL AND HYPERTENSIVE PULMONARY VASCULATURE
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mocumbi A, Humbert M, Saxena A, Jing ZC, Sliwa K, Thienemann F, Archer SL, Stewart S. Pulmonary hypertension. Nat Rev Dis Primers. 2024 Jan 04; 10(1):1. PMID: 38177157.
      Citations:    Fields:    Translation:Humans
    2. Piao L, Fang YH, Fisher M, Hamanaka RB, Ousta A, Wu R, Mutlu GM, Garcia AJ, Archer SL, Sharp WW. Dynamin-related protein 1 is a critical regulator of mitochondrial calcium homeostasis during myocardial ischemia/reperfusion injury. FASEB J. 2024 01; 38(1):e23379. PMID: 38133921.
      Citations:    Fields:    Translation:AnimalsCells
    3. Al-Qazazi R, Emon IM, Potus F, Martin AY, Lima PDA, Vlasschaert C, Chen KH, Wu D, Gupta AD, Noordhof C, Jefferson L, McNaughton AJM, Bick AG, Pauciulo MW, Nichols WC, Chung WK, Hassoun PM, Damico RL, Rauh MJ, Archer SL. Germline and Somatic Mutations in DNA Methyltransferase 3A (DNMT3A) Predispose to Pulmonary Arterial Hypertension (PAH) in Humans and Mice: Implications for Associated PAH. medRxiv. 2023 Dec 31. PMID: 38234783; PMCID: PMC10793539.
      Citations:    
    4. Wu D, Jansen-van Vuuren RD, Dasgupta A, Al-Qazazi R, Chen KH, Martin A, Mewburn JD, Alizadeh E, Lima PDA, Jones O, Colpman P, Breault NM, Emon IM, Jedlovcnik L, Zhao YY, Wells M, Sutendra G, Archer SL. Efficacy of Drpitor1a, a Dynamin-Related Protein 1 inhibitor, in Pulmonary Arterial Hypertension. bioRxiv. 2023 Dec 23. PMID: 38187628; PMCID: PMC10769396.
      Citations:    
    5. Thomas ECM, Finnen RL, Mewburn JD, Archer SL, Banfield BW. The Herpes Simplex Virus pUL16 and pUL21 Proteins Prevent Capsids from Docking at Nuclear Pore Complexes. PLoS Pathog. 2023 Dec; 19(12):e1011832. PMID: 38039340; PMCID: PMC10718459.
      Citations:    Fields:    Translation:HumansCells
    6. Prins KW, Durbin J, Archer SL, Prins KW, Durbin J, Archer SL. Complete Revascularization of the Pulmonary Circulation in Chronic Thromboembolic Pulmonary Hypertension: Value of Addressing Chronic Total Occlusions. Can J Cardiol. 2024 Apr; 40(4):634-636. PMID: 38030122; PMCID: PMC11009058.
      Citations:    Fields:    
    7. Emon IM, Al-Qazazi R, Rauh MJ, Archer SL. The Role of Clonal Hematopoiesis of Indeterminant Potential and DNA (Cytosine-5)-Methyltransferase Dysregulation in Pulmonary Arterial Hypertension and Other Cardiovascular Diseases. Cells. 2023 10 26; 12(21). PMID: 37947606; PMCID: PMC10650407.
      Citations: 1     Fields:    Translation:Humans
    8. Mendelson JB, Sternbach JD, Doyle MJ, Mills L, Hartweck LM, Tollison W, Carney JP, Lahti MT, Bianco RW, Kalra R, Kazmirczak F, Hindmarch C, Archer SL, Prins KW, Martin CM. Multi-omic and multispecies analysis of right ventricular dysfunction. J Heart Lung Transplant. 2024 Feb; 43(2):303-313. PMID: 37783299; PMCID: PMC10841898.
      Citations:    Fields:    Translation:HumansAnimals
    9. Colpman P, Dasgupta A, Archer SL. The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases. Cells. 2023 07 20; 12(14). PMID: 37508561; PMCID: PMC10378656.
      Citations: 1     Fields:    Translation:Humans
    10. Read AD, Bentley RET, Martin AY, Mewburn JD, Alizadeh E, Wu D, Lima PDA, Dunham-Snary KJ, Thébaud B, Sharp W, Archer SL. Electron Leak From the Mitochondrial Electron Transport Chain Complex I at Site IQ Is Crucial for Oxygen Sensing in Rabbit and Human Ductus Arteriosus. J Am Heart Assoc. 2023 07 04; 12(13):e029131. PMID: 37345832; PMCID: PMC10356098.
      Citations:    Fields:    Translation:HumansAnimalsCells
    11. Burrows AG, Linton S, Thiele J, Sheth PM, Evans GA, Archer S, Doliszny KM, Finlayson M, Flynn L, Huang Y, Kasmani A, Hugh Guan T, Maier A, Hansen-Taugher A, Moore K, Sanfilippo A, Snelgrove-Clarke E, Tripp DA, Walker DMC, Vanner S, Ellis AK. Asymptomatic surveillance testing for COVID-19 in health care professional students: lessons learned from a low prevalence setting. Allergy Asthma Clin Immunol. 2023 Mar 29; 19(1):25. PMID: 36991486; PMCID: PMC10057685.
      Citations:    
    12. Chang KY, Giorgio K, Schmitz K, Walker RF, Prins KW, Pritzker MR, Archer SL, Lutsey PL, Thenappan T. Effect of Chronic Digoxin Use on Mortality and Heart Failure Hospitalization in Pulmonary Arterial Hypertension. J Am Heart Assoc. 2023 03 21; 12(6):e027559. PMID: 36892094; PMCID: PMC10111549.
      Citations: 2     Fields:    Translation:Humans
    13. Bentley RET, Hindmarch CCT, Archer SL. Using omics to breathe new life into our understanding of the ductus arteriosus oxygen response. Semin Perinatol. 2023 03; 47(2):151715. PMID: 36906478.
      Citations:    Fields:    Translation:Humans
    14. Mendelson JB, Sternbach JD, Doyle MJ, Mills L, Hartweck LM, Tollison W, Carney JP, Lahti MT, Bianco RW, Kalra R, Kazmirczak F, Hindmarch C, Archer SL, Prins KW, Martin CM. A Multi-omic and Multi-Species Analysis of Right Ventricular Failure. bioRxiv. 2023 Feb 08. PMID: 36798212; PMCID: PMC9934613.
      Citations:    
    15. Breault NM, Wu D, Dasgupta A, Chen KH, Archer SL. Acquired disorders of mitochondrial metabolism and dynamics in pulmonary arterial hypertension. Front Cell Dev Biol. 2023; 11:1105565. PMID: 36819102; PMCID: PMC9933518.
      Citations: 3     
    16. Hindmarch CCT, Tian L, Xiong PY, Potus F, Bentley RET, Al-Qazazi R, Prins KW, Archer SL. An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats. Front Physiol. 2022; 13:966454. PMID: 36388115; PMCID: PMC9664166.
      Citations: 4     
    17. Archer SL, Dasgupta A, Chen KH, Wu D, Baid K, Mamatis JE, Gonzalez V, Read A, Bentley RE, Martin AY, Mewburn JD, Dunham-Snary KJ, Evans GA, Levy G, Jones O, Al-Qazazi R, Ring B, Alizadeh E, Hindmarch CC, Rossi J, Lima PD, Falzarano D, Banerjee A, Colpitts CC. SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia. Redox Biol. 2022 Dec; 58:102508. PMID: 36334378; PMCID: PMC9558649.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    18. Al-Qazazi R, Lima PDA, Prisco SZ, Potus F, Dasgupta A, Chen KH, Tian L, Bentley RET, Mewburn J, Martin AY, Wu D, Jones O, Maurice DH, Prins KW, Archer SL, Bonnet S, Provencher S. Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2022 09 01; 206(5):608-624. PMID: 35699679; PMCID: PMC9716901.
      Citations: 22     Fields:    Translation:AnimalsCells
    19. Archer SL, Islam O, Walker R, Neder JA, Melanson M, Abunassar J, Smith C. Exertional Dyspnea and Chronotropic Incompetence Caused by Extrinsic Compression of the Right Carotid Body by a Giant Lipoma. Can J Cardiol. 2022 Oct; 38(10):1588-1590. PMID: 35716961.
      Citations:    Fields:    Translation:HumansCells
    20. Romani P, Nirchio N, Arboit M, Barbieri V, Tosi A, Michielin F, Shibuya S, Benoist T, Wu D, Hindmarch CCT, Giomo M, Urciuolo A, Giamogante F, Roveri A, Chakravarty P, Montagner M, Elvassore N, Archer SL, De Coppi P, Rosato A, Martello G, Dupont S, Calì T. Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance. Nat Cell Biol. 2022 02; 24(2):168-180. PMID: 35165418; PMCID: PMC7615745.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    21. Wijeratne DT, Housin A, Lajkosz K, Lougheed MD, Xiong PY, Barber D, Doliszny KM, Archer SL. Using health administrative data to identify patients with pulmonary hypertension: A single center, proof of concept validation study in Ontario, Canada. Pulm Circ. 2022 Jan; 12(1):e12040. PMID: 35506095; PMCID: PMC9052993.
      Citations: 1     
    22. Xiong PY, Motamed M, Chen KH, Dasgupta A, Tian L, Martin A, Mewburn J, Jones O, Archer SL, Potus F, Thébaud A. Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding. Acta Physiol (Oxf). 2022 02; 234(2):e13764. PMID: 34978755; PMCID: PMC8810721.
      Citations:    Fields:    Translation:Animals
    23. Dunham-Snary KJ, Surewaard BG, Mewburn JD, Bentley RE, Martin AY, Jones O, Al-Qazazi R, Lima PA, Kubes P, Archer SL. Mitochondria in human neutrophils mediate killing of Staphylococcus aureus. Redox Biol. 2022 02; 49:102225. PMID: 34959099; PMCID: PMC8758915.
      Citations: 21     Fields:    Translation:HumansCells
    24. Prisco SZ, Hartweck LM, Rose L, Lima PDA, Thenappan T, Archer SL, Prins KW. Inflammatory Glycoprotein 130 Signaling Links Changes in Microtubules and Junctophilin-2 to Altered Mitochondrial Metabolism and Right Ventricular Contractility. Circ Heart Fail. 2022 01; 15(1):e008574. PMID: 34923829; PMCID: PMC8766918.
      Citations: 11     Fields:    Translation:AnimalsCells
    25. Bentley RET, Hindmarch CCT, Dunham-Snary KJ, Snetsinger B, Mewburn JD, Lima PDA, Archer SL, Thébaud A, Thébaud B. The comprehensive transcriptome of human ductus arteriosus smooth muscle cells (hDASMC). Data Brief. 2022 Feb; 40:107736. PMID: 35005134; PMCID: PMC8717140.
      Citations: 1     
    26. Read AD, Bentley RE, Archer SL, Dunham-Snary KJ. Mitochondrial iron-sulfur clusters: Structure, function, and an emerging role in vascular biology. Redox Biol. 2021 11; 47:102164. PMID: 34656823; PMCID: PMC8577454.
      Citations: 40     Fields:    Translation:Cells
    27. Hanson MG, Abuzeid W, Archer SL. Anomalous Right Coronary Artery Arising From Distal Left Circumflex Artery. CJC Open. 2022 Jan; 4(1):112-113. PMID: 35072034; PMCID: PMC8767128.
      Citations:    
    28. Dasgupta A, Chen KH, Lima PDA, Mewburn J, Wu D, Al-Qazazi R, Jones O, Tian L, Potus F, Archer SL, Bonnet S. PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension. FASEB J. 2021 08; 35(8):e21771. PMID: 34275172; PMCID: PMC8294132.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    29. Archer SL, Adão R. Corrigendum to: Scientist on the spot: Exploring the cause and cure for pulmonary arterial hypertension. Cardiovasc Res. 2021 Jul 27; 117(9):2068. PMID: 34143877.
      Citations:    Fields:    
    30. Thenappan T, Weir EK, Prins KW, Pritzker MR, Archer SL. Carvedilol for Treatment of Right Ventricular Dysfunction in Pulmonary Arterial Hypertension. J Am Heart Assoc. 2021 07 20; 10(14):e021518. PMID: 34259020; PMCID: PMC8483454.
      Citations: 1     Fields:    Translation:Humans
    31. Bentley RET, Hindmarch CCT, Dunham-Snary KJ, Snetsinger B, Mewburn JD, Lima PDA, Archer SL, Thébaud A, Thébaud B. The molecular mechanisms of oxygen-sensing in human ductus arteriosus smooth muscle cells: A comprehensive transcriptome profile reveals a central role for mitochondria. Genomics. 2021 09; 113(5):3128-3140. PMID: 34245829; PMCID: PMC10659099.
      Citations: 5     Fields:    Translation:HumansCells
    32. Leopold JA, Kawut SM, Aldred MA, Archer SL, Benza RL, Bristow MR, Brittain EL, Chesler N, DeMan FS, Erzurum SC, Gladwin MT, Hassoun PM, Hemnes AR, Lahm T, Lima JAC, Loscalzo J, Maron BA, Rosa LM, Newman JH, Redline S, Rich S, Rischard F, Sugeng L, Tang WHW, Tedford RJ, Tsai EJ, Ventetuolo CE, Zhou Y, Aggarwal NR, Xiao L. Diagnosis and Treatment of Right Heart Failure in Pulmonary Vascular Diseases: A National Heart, Lung, and Blood Institute Workshop. Circ Heart Fail. 2021 06; 14(6). PMID: 34422205; PMCID: PMC8375628.
      Citations: 4     Fields:    Translation:Humans
    33. Archer SL, da Costa Adão RM. Scientist on the Spot: Exploring the cause and cure for pulmonary arterial hypertension. Cardiovasc Res. 2021 05 25; 117(6):e82-e83. PMID: 34021303.
      Citations:    Fields:    Translation:Humans
    34. Wu D, Dasgupta A, Read AD, Bentley RET, Motamed M, Chen KH, Al-Qazazi R, Mewburn JD, Dunham-Snary KJ, Alizadeh E, Tian L, Archer SL. Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer. Free Radic Biol Med. 2021 07; 170:150-178. PMID: 33450375; PMCID: PMC8217091.
      Citations: 16     Fields:    Translation:Humans
    35. Edginton S, D'Arsigny CL, McLellan C, Archer SL. Left Main Coronary Artery Compression in Pulmonary Arterial Hypertension: Percutaneous Treatment to Improve Symptoms. CJC Open. 2021 May; 3(5):690-692. PMID: 34027375; PMCID: PMC8134911.
      Citations:    
    36. Vijayaraghavan M, Prins KW, Prisco SZ, Duval S, John R, Archer SL, Weir EK, Voeller R, Shaffer AW, Thenappan T. Hemodynamic Characteristics and Outcomes of Pulmonary Hypertension in Patients Undergoing Tricuspid Valve Repair or Replacement. CJC Open. 2021 Apr; 3(4):488-497. PMID: 34027352; PMCID: PMC8129475.
      Citations:    
    37. Theilmann AL, Hawke LG, Hilton LR, Whitford MKM, Cole DV, Mackeil JL, Dunham-Snary KJ, Mewburn J, James PD, Maurice DH, Archer SL, Ormiston ML. Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling. Arterioscler Thromb Vasc Biol. 2020 11; 40(11):2605-2618. PMID: 32998516; PMCID: PMC7571847.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    38. Prisco SZ, Rose L, Potus F, Tian L, Wu D, Hartweck L, Al-Qazazi R, Neuber-Hess M, Eklund M, Hsu S, Thenappan T, Archer SL, Prins KW. Excess Protein O-GlcNAcylation Links Metabolic Derangements to Right Ventricular Dysfunction in Pulmonary Arterial Hypertension. Int J Mol Sci. 2020 Oct 01; 21(19). PMID: 33019763; PMCID: PMC7582480.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    39. Potus F, Lin JH, Zafar H, Kiely DG, Lawrie A, Archer SL, Omura J, Habbout K, Shimauchi T, Wu WH, Breuils-Bonnet S, Tremblay E, Martineau S, Nadeau V, Gagnon K, Mazoyer F, Perron J, Paulin R, Provencher S, Boucherat O, Bonnet S. Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension. Circulation. 2020 10 13; 142(15):1464-1484. PMID: 32698630.
      Citations: 64     Fields:    Translation:HumansAnimals
    40. Archer SL. Providing care for the 99.9% during the COVID-19 pandemic: How ethics, equity, epidemiology, and cost per QALY inform healthcare policy. Healthc Manage Forum. 2020 Sep; 33(5):239-242. PMID: 32638633.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    41. Potus F, Martin AY, Snetsinger B, Archer SL. Biventricular Assessment of Cardiac Function and Pressure-Volume Loops by Closed-Chest Catheterization in Mice. J Vis Exp. 2020 06 15; (160). PMID: 32597858.
      Citations: 3     Fields:    Translation:Animals
    42. Tian L, Xiong PY, Alizadeh E, Lima PDA, Mewburn J, Martin A, Chen KH, Archer SL, Potus F. Supra-coronary aortic banding improves right ventricular function in experimental pulmonary arterial hypertension in rats by increasing systolic right coronary artery perfusion. Acta Physiol (Oxf). 2020 08; 229(4):e13483. PMID: 32339403; PMCID: PMC7363583.
      Citations: 6     Fields:    Translation:Animals
    43. Archer SL, Sharp WW, Weir EK. Differentiating COVID-19 Pneumonia From Acute Respiratory Distress Syndrome and High Altitude Pulmonary Edema: Therapeutic Implications. Circulation. 2020 07 14; 142(2):101-104. PMID: 32369390; PMCID: PMC7363563.
      Citations: 85     Fields:    Translation:HumansCellsPHPublic Health
    44. Xiong PY, Jaff Z, D'Arsigny CL, Archer SL, Wijeratne DT. Evaluation of the Impact of an Echocardiographic Diagnosis of Pulmonary Hypertension on Patient Outcomes. CJC Open. 2020 Sep; 2(5):328-336. PMID: 32995717; PMCID: PMC7499396.
      Citations: 4     
    45. Tian L, Wu D, Dasgupta A, Chen KH, Mewburn J, Potus F, Lima PDA, Hong Z, Zhao YY, Hindmarch CCT, Kutty S, Provencher S, Bonnet S, Sutendra G, Archer SL. Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis. Circ Res. 2020 06 05; 126(12):1723-1745. PMID: 32216531; PMCID: PMC7274861.
      Citations: 47     Fields:    Translation:AnimalsCells
    46. Pauciulo MW, Cook EK, Zhu N, Hsieh A, Welch CL, Shen Y, Tian L, Lima P, Mewburn J, D'Arsigny CL, Lutz KA, Coleman AW, Damico R, Snetsinger B, Martin AY, Hassoun PM, Nichols WC, Chung WK, Rauh MJ, Archer SL, Potus F. Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension. Circulation. 2020 06 16; 141(24):1986-2000. PMID: 32192357; PMCID: PMC7299806.
      Citations: 47     Fields:    Translation:HumansAnimals
    47. Dasgupta A, Wu D, Tian L, Xiong PY, Dunham-Snary KJ, Chen KH, Alizadeh E, Motamed M, Hindmarch CCT, Archer SL, Potus F. Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen-Sensing, Metabolism, and Dynamics. Compr Physiol. 2020 03 12; 10(2):713-765. PMID: 32163206.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    48. Prins KW, Kalra R, Rose L, Assad TR, Archer SL, Bajaj NS, Weir EK, Prisco SZ, Pritzker M, Lutsey PL, Brittain EL, Thenappan T. Hypochloremia Is a Noninvasive Predictor of Mortality in Pulmonary Arterial Hypertension. J Am Heart Assoc. 2020 03 03; 9(5):e015221. PMID: 32079477; PMCID: PMC7335577.
      Citations: 5     Fields:    Translation:Humans
    49. Dasgupta A, Chen KH, Wu D, Hoskin V, Mewburn J, Lima PDA, Parlow LRG, Hindmarch CCT, Martin A, Sykes EA, Tayade C, Lightbody ED, Madarnas Y, SenGupta SK, Elliott BE, Nicol CJB, Archer SL. An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications. FASEB J. 2020 04; 34(4):5106-5127. PMID: 32068312.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    50. Piao L, Fang YH, Hamanaka RB, Dezfulian C, Archer SL, Sharp WW, Mutlu GM. Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes. Crit Care Med. 2020 02; 48(2):e133-e140. PMID: 31939812; PMCID: PMC6964871.
      Citations: 12     Fields:    Translation:AnimalsCells
    51. Wu D, Dasgupta A, Chen KH, Neuber-Hess M, Patel J, Hurst TE, Mewburn JD, Lima PDA, Alizadeh E, Martin A, Wells M, Snieckus V, Archer SL. Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury. FASEB J. 2020 01; 34(1):1447-1464. PMID: 31914641.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    52. Piao L, Fang YH, Hamanaka RB, Mutlu GM, Dezfulian C, Archer SL, Sharp WW. Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes. Crit Care Med. 2019 Nov 13. PMID: 31725436.
      Citations:    
    53. Appireddy R, Khan S, Leaver C, Martin C, Jin A, Durafourt BA, Archer SL. Home Virtual Visits for Outpatient Follow-Up Stroke Care: Cross-Sectional Study. J Med Internet Res. 2019 10 07; 21(10):e13734. PMID: 31593536; PMCID: PMC6803894.
      Citations: 27     Fields:    Translation:Humans
    54. Dunham-Snary KJ, Archer SL. Response by Dunham-Snary and Archer to Letter Regarding Article, "Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction". Circ Res. 2019 09 27; 125(8):e35-e36. PMID: 31557123; PMCID: PMC7144885.
      Citations:    Fields:    Translation:Humans
    55. Archer SL, Ranchoux B, Nadeau V, Bourgeois A, Provencher S, Tremblay É, Omura J, Coté N, Abu-Alhayja'a R, Dumais V, Nachbar RT, Tastet L, Dahou A, Breuils-Bonnet S, Marette A, Pibarot P, Dupuis J, Paulin R, Boucherat O, Bonnet S, Potus F. Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease. Circ Res. 2019 08 02; 125(4):449-466. PMID: 31154939.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    56. Dunham-Snary KJ, Wu D, Sykes EA, Mewburn JD, Sultanian RA, Archer SL, Potus F, Charles RL, Eaton P. Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction. Circ Res. 2019 06 07; 124(12):1727-1746. PMID: 30922174; PMCID: PMC6554062.
      Citations: 40     Fields:    Translation:AnimalsCells
    57. Xiong PY, Tian L, Dunham-Snary KJ, Chen KH, Mewburn JD, Neuber-Hess M, Martin A, Dasgupta A, Potus F, Archer SL. Biventricular Increases in Mitochondrial Fission Mediator (MiD51) and Proglycolytic Pyruvate Kinase (PKM2) Isoform in Experimental Group 2 Pulmonary Hypertension-Novel Mitochondrial Abnormalities. Front Cardiovasc Med. 2018; 5:195. PMID: 30740395; PMCID: PMC6355690.
      Citations: 12     
    58. Prins KW, Rose L, Archer SL, Pritzker M, Weir EK, Olson MD, Thenappan T. Clinical Determinants and Prognostic Implications of Right Ventricular Dysfunction in Pulmonary Hypertension Caused by Chronic Lung Disease. J Am Heart Assoc. 2019 01 22; 8(2):e011464. PMID: 30646788; PMCID: PMC6497344.
      Citations: 27     Fields:    Translation:Humans
    59. Prins KW, Thenappan T, Weir EK, Kalra R, Pritzker M, Archer SL. Repurposing Medications for Treatment of Pulmonary Arterial Hypertension: What's Old Is New Again. J Am Heart Assoc. 2019 01 08; 8(1):e011343. PMID: 30590974; PMCID: PMC6405714.
      Citations: 33     Fields:    Translation:Humans
    60. Cirulis MM, Ryan JJ, Archer SL. Pathophysiology, incidence, management, and consequences of cardiac arrhythmia in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Pulm Circ. 2019 Jan-Mar; 9(1):2045894019834890. PMID: 30747032; PMCID: PMC6410395.
      Citations: 16     
    61. Rhodes CJ, Batai K, Bleda M, Haimel M, Southgate L, Pauciulo MW, Hadinnapola C, Aman J, Arora A, Knight J, Hanscombe KB, Karnes JH, Kaakinen M, Gall H, Ulrich A, Harbaum L, Ferrer J, Lutz K, Swietlik EM, Ahmad F, Amouyel P, Archer SL, Argula R, Austin ED, Badesch D, Bakshi S, Barnett C, Benza R, Bhatt N, Bogaard HJ, Burger CD, Chakinala M, Church C, Coghlan JG, Condliffe R, Corris PA, Danesino C, Elliott CG, Elwing J, Fortin T, Franke A, Frantz RP, Frost A, Garcia JGN, Ghio S, Ghofrani HA, Gibbs JSR, Harley J, He H, Hill NS, Hirsch R, Houweling AC, Howard LS, Ivy D, Kiely DG, Klinger J, Kovacs G, Lahm T, Laudes M, Machado RD, MacKenzie Ross RV, Marsolo K, Martin LJ, Moledina S, Nathan SD, Newnham M, Olschewski A, Olschewski H, Oudiz RJ, Ouwehand WH, Peacock AJ, Pepke-Zaba J, Rehman Z, Robbins I, Roden DM, Rosenzweig EB, Saydain G, Scelsi L, Schilz R, Seeger W, Shaffer CM, Simms RW, Simon M, Suntharalingam J, Tang H, Tchourbanov AY, Thenappan T, Torres F, Toshner MR, Treacy CM, Vonk Noordegraaf A, Waisfisz Q, Walsworth AK, Walter RE, Wharton J, White RJ, Wilt J, Wort SJ, Yung D, Lawrie A, Prokopenko I, Kittles R, Nichols WC, Trembath RC, Desai AA, Morrell NW, Wilkins MR, UK NIHR BioResource Rare Diseases Consortium, UK PAH Cohort Study Consortium, US PAH Biobank Consortium, Germain M, Girerd B, Cebola I, Debette S, Eyries M, Montani D, Sitbon O, Humbert M, Soubrier F, Trégouët DA, Gräf S. Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis. Lancet Respir Med. 2019 03; 7(3):227-238. PMID: 30527956; PMCID: PMC6391516.
      Citations: 81     Fields:    Translation:HumansCells
    62. Xiong PY, Baba S, Nishioka N, Fujimoto Y, Archer SL, Minamisawa S. Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat. J Vis Exp. 2018 11 18; (141). PMID: 30507912.
      Citations: 4     Fields:    Translation:Animals
    63. Rose L, Prins KW, Archer SL, Pritzker M, Weir EK, Misialek JR, Thenappan T. Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide. J Heart Lung Transplant. 2019 02; 38(2):145-155. PMID: 30391191; PMCID: PMC6556403.
      Citations: 27     Fields:    Translation:Humans
    64. Potus F, Hindmarch CCT, Dunham-Snary KJ, Stafford J, Archer SL. Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities. Int J Mol Sci. 2018 Sep 12; 19(9). PMID: 30213070; PMCID: PMC6164263.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    65. Lahm T, Douglas IS, Archer SL, Bogaard HJ, Chesler NC, Haddad F, Hemnes AR, Kawut SM, Kline JA, Kolb TM, Mathai SC, Mercier O, Michelakis ED, Naeije R, Tuder RM, Ventetuolo CE, Vieillard-Baron A, Voelkel NF, Vonk-Noordegraaf A, Hassoun PM, American Thoracic Society Assembly on Pulmonary Circulation. Assessment of Right Ventricular Function in the Research Setting: Knowledge Gaps and Pathways Forward. An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med. 2018 08 15; 198(4):e15-e43. PMID: 30109950; PMCID: PMC6835085.
      Citations: 117     Fields:    Translation:HumansAnimals
    66. D'Arsigny CL, Archer SL. A Step Closer to Understanding How Riociguat Results in Remodelling of the Right Ventricle in Chronic Thromboembolic Pulmonary Hypertension. Can J Cardiol. 2018 09; 34(9):1098-1101. PMID: 30170664.
      Citations:    Fields:    Translation:Humans
    67. Tian L, Potus F, Wu D, Dasgupta A, Chen KH, Mewburn J, Lima P, Archer SL. Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension. Front Physiol. 2018; 9:828. PMID: 30042687; PMCID: PMC6048272.
      Citations: 35     
    68. Nicolls MR, Olschewski A, Abe K, Rabinovitch M, Stewart D, Chan SY, Morrell NW, Archer SL, Spiekerkoetter E, Kuebler WM. A pro-con debate: current controversies in PAH pathogenesis at the American Thoracic Society International Conference in 2017. Am J Physiol Lung Cell Mol Physiol. 2018 10 01; 315(4):L502-L516. PMID: 29877097; PMCID: PMC6230875.
      Citations: 8     Fields:    Translation:HumansAnimals
    69. Prins KW, Rose L, Archer SL, Pritzker M, Weir EK, Kazmirczak F, Misialek JR, Thenappan T. Disproportionate Right Ventricular Dysfunction and Poor Survival in Group 3 Pulmonary Hypertension. Am J Respir Crit Care Med. 2018 06 01; 197(11):1496-1499. PMID: 29360393; PMCID: PMC6005552.
      Citations: 20     Fields:    Translation:Humans
    70. Provencher S, Archer SL, Ramirez FD, Hibbert B, Paulin R, Boucherat O, Lacasse Y, Bonnet S. Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research. Circ Res. 2018 03 30; 122(7):1021-1032. PMID: 29599278.
      Citations: 59     Fields:    Translation:HumansAnimals
    71. Thenappan T, Ormiston ML, Ryan JJ, Archer SL. Pulmonary arterial hypertension: pathogenesis and clinical management. BMJ. 2018 03 14; 360:j5492. PMID: 29540357; PMCID: PMC6889979.
      Citations: 351     Fields:    Translation:Humans
    72. Chen KH, Dasgupta A, Lin J, Iremonger J, Fu J, Mewburn J, Wu D, Dunham-Snary K, Theilmann AL, Jing ZC, Hindmarch C, Ormiston ML, Lawrie A, Archer SL, Potus F, Bonnet S. Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications. Circulation. 2018 07 17; 138(3):287-304. PMID: 29431643; PMCID: PMC6050130.
      Citations: 71     Fields:    Translation:HumansAnimalsCells
    73. Wijeratne DT, Lajkosz K, Brogly SB, Lougheed MD, Jiang L, Housin A, Barber D, Johnson A, Doliszny KM, Archer SL. Increasing Incidence and Prevalence of World Health Organization Groups 1 to 4 Pulmonary Hypertension: A Population-Based Cohort Study in Ontario, Canada. Circ Cardiovasc Qual Outcomes. 2018 02; 11(2):e003973. PMID: 29444925; PMCID: PMC5819352.
      Citations: 99     Fields:    Translation:Humans
    74. Archer SL. Pyruvate Kinase and Warburg Metabolism in Pulmonary Arterial Hypertension: Uncoupled Glycolysis and the Cancer-Like Phenotype of Pulmonary Arterial Hypertension. Circulation. 2017 12 19; 136(25):2486-2490. PMID: 29255124; PMCID: PMC5739072.
      Citations: 31     Fields:    Translation:HumansCells
    75. Xiong PY, Potus F, Chan W, Archer SL. Models and Molecular Mechanisms of World Health Organization Group 2 to 4 Pulmonary Hypertension. Hypertension. 2018 01; 71(1):34-55. PMID: 29158355; PMCID: PMC5777609.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    76. Selvam SN, Casey LJ, Bowman ML, Hawke LG, Longmore AJ, Mewburn J, Ormiston ML, Archer SL, Maurice DH, James P. Abnormal angiogenesis in blood outgrowth endothelial cells derived from von Willebrand disease patients. Blood Coagul Fibrinolysis. 2017 Oct; 28(7):521-533. PMID: 28362648; PMCID: PMC5960581.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    77. Prins KW, Archer SL, Pritzker M, Rose L, Weir EK, Sharma A, Thenappan T. Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension. J Heart Lung Transplant. 2018 03; 37(3):376-384. PMID: 28893516; PMCID: PMC5854490.
      Citations: 45     Fields:    Translation:Humans
    78. Prins KW, Tian L, Wu D, Thenappan T, Metzger JM, Archer SL. Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension. J Am Heart Assoc. 2017 May 31; 6(6). PMID: 28566298; PMCID: PMC5669202.
      Citations: 33     Fields:    Translation:AnimalsCells
    79. Tian L, Neuber-Hess M, Mewburn J, Dasgupta A, Dunham-Snary K, Wu D, Chen KH, Hong Z, Sharp WW, Kutty S, Archer SL. Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension. J Mol Med (Berl). 2017 04; 95(4):381-393. PMID: 28265681; PMCID: PMC5390778.
      Citations: 55     Fields:    Translation:AnimalsCells
    80. Hong Z, Chen KH, DasGupta A, Potus F, Dunham-Snary K, Bonnet S, Tian L, Fu J, Breuils-Bonnet S, Provencher S, Wu D, Mewburn J, Ormiston ML, Archer SL. MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype. Am J Respir Crit Care Med. 2017 Feb 15; 195(4):515-529. PMID: 27648837; PMCID: PMC5378421.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    81. Thenappan T, Archer SL, Weir EK. Resistance over compliance describes right ventricular afterload better than resistance-compliance time: a friendly amendment. Pulm Circ. 2017 Mar; 7(1):275. PMID: 28680587; PMCID: PMC5448527.
      Citations:    
    82. Prins KW, Weir EK, Archer SL, Markowitz J, Rose L, Pritzker M, Madlon-Kay R, Thenappan T. Pulmonary pulse wave transit time is associated with right ventricular-pulmonary artery coupling in pulmonary arterial hypertension. Pulm Circ. 2016 Dec; 6(4):576-585. PMID: 28090301; PMCID: PMC5210075.
      Citations: 18     
    83. Anand V, Roy SS, Archer SL, Weir EK, Garg SK, Duval S, Thenappan T. Trends and Outcomes of Pulmonary Arterial Hypertension-Related Hospitalizations in the United States: Analysis of the Nationwide Inpatient Sample Database From 2001 Through 2012. JAMA Cardiol. 2016 Dec 01; 1(9):1021-1029. PMID: 27851838.
      Citations: 48     Fields:    
    84. Atkins K, Dasgupta A, Chen KH, Mewburn J, Archer SL. The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease. Clin Sci (Lond). 2016 11 01; 130(21):1861-74. PMID: 27660309.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    85. Abman SH, Ivy DD, Archer SL, Wilson K, AHA/ATS Joint Guidelines for Pediatric Pulmonary Hypertension Committee. Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension. Am J Respir Crit Care Med. 2016 Oct 01; 194(7):898-906. PMID: 27689707; PMCID: PMC5074658.
      Citations: 22     Fields:    
    86. Dunham-Snary KJ, Wu D, Sykes EA, Thakrar A, Parlow LRG, Mewburn JD, Parlow JL, Archer SL. Hypoxic Pulmonary Vasoconstriction: From Molecular Mechanisms to Medicine. Chest. 2017 Jan; 151(1):181-192. PMID: 27645688; PMCID: PMC5310129.
      Citations: 151     Fields:    Translation:Humans
    87. Hemnes AR, Zhao M, West J, Newman JH, Rich S, Archer SL, Robbins IM, Blackwell TS, Cogan J, Loyd JE, Zhao Z, Gaskill C, Jetter C, Kropski JA, Majka SM, Austin ED. Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2016 08 15; 194(4):464-75. PMID: 26926454; PMCID: PMC5003329.
      Citations: 44     Fields:    Translation:Humans
    88. Wu D, Archer SL. Pulmonary hypertension begets pulmonary hypertension: mutually reinforcing roles for haemodynamics, inflammation, and cancer-like phenotypes. Cardiovasc Res. 2016 07 01; 111(1):1-4. PMID: 27216865; PMCID: PMC4909166.
      Citations: 2     Fields:    Translation:Humans
    89. Archer SL. Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibition of Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: Therapeutic Implications. Adv Exp Med Biol. 2016; 903:29-53. PMID: 27343087.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    90. Abman SH, Hansmann G, Archer SL, Ivy DD, Adatia I, Chung WK, Hanna BD, Rosenzweig EB, Raj JU, Cornfield D, Stenmark KR, Steinhorn R, Fineman JR, Kuehne T, Feinstein JA, Friedberg MK, Earing M, Barst RJ, Keller RL, Kinsella JP, Mullen M, Deterding R, Kulik T, Mallory G, Humpl T, Wessel DL, American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitatio, Thébaud B. Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society. Circulation. 2015 Nov 24; 132(21):2037-99. PMID: 26534956.
      Citations: 351     Fields:    Translation:Humans
    91. Dasgupta A, Chen KH, Tian L, Archer SL. Gone fission: an asymptomatic STAT2 mutation elongates mitochondria and causes human disease following viral infection. Brain. 2015 Oct; 138(Pt 10):2802-6. PMID: 26408653; PMCID: PMC6382152.
      Citations: 3     Fields:    Translation:HumansCells
    92. Dunham-Snary KJ, Hong ZG, Xiong PY, Del Paggio JC, Herr JE, Johri AM, Archer SL. A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus. Pflugers Arch. 2016 Jan; 468(1):43-58. PMID: 26395471; PMCID: PMC4703457.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    93. Ryan JJ, Archer SL. Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertension. Circulation. 2015 May 12; 131(19):1691-702. PMID: 25964279; PMCID: PMC4429908.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    94. Ryan J, Dasgupta A, Huston J, Chen KH, Archer SL. Mitochondrial dynamics in pulmonary arterial hypertension. J Mol Med (Berl). 2015 Mar; 93(3):229-42. PMID: 25672499; PMCID: PMC4339102.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    95. Sharp WW, Archer SL. Mitochondrial dynamics in cardiovascular disease: fission and fusion foretell form and function. J Mol Med (Berl). 2015 Mar; 93(3):225-8. PMID: 25669447; PMCID: PMC4338002.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    96. Sharp WW, Beiser DG, Fang YH, Han M, Piao L, Varughese J, Archer SL. Inhibition of the mitochondrial fission protein dynamin-related protein 1 improves survival in a murine cardiac arrest model. Crit Care Med. 2015 Feb; 43(2):e38-47. PMID: 25599491; PMCID: PMC4342059.
      Citations: 42     Fields:    Translation:Animals
    97. Ryan JJ, Huston J, Kutty S, Hatton ND, Bowman L, Tian L, Herr JE, Johri AM, Archer SL. Right ventricular adaptation and failure in pulmonary arterial hypertension. Can J Cardiol. 2015 Apr; 31(4):391-406. PMID: 25840092; PMCID: PMC4385216.
      Citations: 70     Fields:    Translation:Humans
    98. Dasgupta A, Bowman L, D'Arsigny CL, Archer SL. Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension. Clin Pharmacol Ther. 2015 Jan; 97(1):88-102. PMID: 25670386; PMCID: PMC4325399.
      Citations: 40     Fields:    Translation:HumansAnimals
    99. Hemnes AR, Trammell AW, Archer SL, Rich S, Yu C, Nian H, Penner N, Funke M, Wheeler L, Robbins IM, Austin ED, Newman JH, West J. Peripheral blood signature of vasodilator-responsive pulmonary arterial hypertension. Circulation. 2015 Jan 27; 131(4):401-9; discussion 409. PMID: 25361553; PMCID: PMC4308423.
      Citations: 48     Fields:    Translation:HumansCells
    100. Tuder RM, Archer SL, Erzurum SC, Guignabert C, Michelakis E, Rabinovitch M, Schermuly R, Stenmark KR, Morrell NW, Dorfmüller P. [Relevant issues in the pathology and pathobiology of pulmonary hypertension]. Turk Kardiyol Dern Ars. 2014 Oct; 42 Suppl 1:5-16. PMID: 25697030.
      Citations: 4     Fields:    
    101. Ryan JJ, Archer SL. The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure. Circ Res. 2014 Jun 20; 115(1):176-88. PMID: 24951766; PMCID: PMC4112290.
      Citations: 178     Fields:    Translation:HumansAnimalsCells
    102. Hong Z, Mahapatra S, Kutty S, Weir EK, Archer SL, Cabrera JA. Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus. J Mol Med (Berl). 2014 Sep; 92(9):995-1007. PMID: 24906456; PMCID: PMC4134409.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    103. Archer SL. Mitochondrial fission and fusion in human diseases. N Engl J Med. 2014 03 13; 370(11):1074. PMID: 24620884.
      Citations: 15     Fields:    Translation:Humans
    104. Dweik RA, Rounds S, Erzurum SC, Archer S, Fagan K, Hassoun PM, Hill NS, Humbert M, Kawut SM, Krowka M, Michelakis E, Morrell NW, Stenmark K, Tuder RM, Newman J, ATS Committee on Pulmonary Hypertension Phenotypes. An official American Thoracic Society Statement: pulmonary hypertension phenotypes. Am J Respir Crit Care Med. 2014 Feb 01; 189(3):345-55. PMID: 24484330; PMCID: PMC4291177.
      Citations: 44     Fields:    Translation:Humans
    105. Tuder RM, Archer SL, Erzurum SC, Michelakis E, Rabinovitch M, Schermuly R, Stenmark KR, Morrell NW, Dorfmüller P, Guignabert C. Relevant issues in the pathology and pathobiology of pulmonary hypertension. J Am Coll Cardiol. 2013 Dec 24; 62(25 Suppl):D4-12. PMID: 24355640; PMCID: PMC3970402.
      Citations: 240     Fields:    Translation:HumansAnimalsCells
    106. Samant SA, Zhang HJ, Hong Z, Pillai VB, Sundaresan NR, Wolfgeher D, Archer SL, Chan DC, Gupta MP. SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress. Mol Cell Biol. 2014 Mar; 34(5):807-19. PMID: 24344202; PMCID: PMC4023816.
      Citations: 176     Fields:    Translation:HumansAnimalsCells
    107. Archer SL. Mitochondrial dynamics--mitochondrial fission and fusion in human diseases. N Engl J Med. 2013 Dec 05; 369(23):2236-51. PMID: 24304053.
      Citations: 475     Fields:    Translation:Humans
    108. Sharp WW, Fang YH, Han M, Zhang HJ, Hong Z, Banathy A, Morrow E, Ryan JJ, Archer SL. Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission. FASEB J. 2014 Jan; 28(1):316-26. PMID: 24076965; PMCID: PMC3868827.
      Citations: 168     Fields:    Translation:AnimalsCells
    109. Prochaska MT, Bergl PA, Patel AR, Moss JD, Archer SL. Atrioventricular heart block and syncope coincident with diagnosis of systemic lupus erythematosus. Can J Cardiol. 2013 Oct; 29(10):1330.e5-1330.e7. PMID: 23916739; PMCID: PMC3904292.
      Citations: 2     Fields:    Translation:Humans
    110. Archer SL. Riociguat for pulmonary hypertension--a glass half full. N Engl J Med. 2013 Jul 25; 369(4):386-8. PMID: 23883383.
      Citations: 11     Fields:    Translation:Humans
    111. Piao L, Fang YH, Parikh K, Ryan JJ, Toth PT, Archer SL. Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension. J Mol Med (Berl). 2013 Oct; 91(10):1185-97. PMID: 23794090; PMCID: PMC3783571.
      Citations: 94     Fields:    Translation:AnimalsCells
    112. Ryan JJ, Marsboom G, Fang YH, Toth PT, Morrow E, Luo N, Piao L, Hong Z, Ericson K, Zhang HJ, Han M, Haney CR, Chen CT, Sharp WW, Archer SL. PGC1a-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension. Am J Respir Crit Care Med. 2013 Apr 15; 187(8):865-78. PMID: 23449689; PMCID: PMC3707374.
      Citations: 100     Fields:    Translation:HumansAnimalsCells
    113. von Gise A, Archer SL, Maclean MR, Hansmann G. The first Keystone Symposia Conference on pulmonary vascular isease and right ventricular dysfunction: Current concepts and future therapies. Pulm Circ. 2013 Apr; 3(2):275-7. PMID: 24015328; PMCID: PMC3757822.
      Citations: 2     
    114. Kim GH, Ryan JJ, Archer SL. The role of redox signaling in epigenetics and cardiovascular disease. Antioxid Redox Signal. 2013 May 20; 18(15):1920-36. PMID: 23480168; PMCID: PMC3624767.
      Citations: 52     Fields:    Translation:HumansCells
    115. Hong Z, Kutty S, Toth PT, Marsboom G, Hammel JM, Chamberlain C, Ryan JJ, Zhang HJ, Sharp WW, Morrow E, Trivedi K, Weir EK, Archer SL. Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus. Circ Res. 2013 Mar 01; 112(5):802-15. PMID: 23334860; PMCID: PMC3957065.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    116. Archer SL, Fang YH, Ryan JJ, Piao L. Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension. Pulm Circ. 2013 Jan; 3(1):144-52. PMID: 23662191; PMCID: PMC3641722.
      Citations: 83     
    117. Ryan JJ, Marsboom G, Archer SL. Rodent models of group 1 pulmonary hypertension. Handb Exp Pharmacol. 2013; 218:105-49. PMID: 24092338.
      Citations: 27     Fields:    Translation:HumansAnimals
    118. Morrell NW, Archer SL, Defelice A, Evans S, Fiszman M, Martin T, Saulnier M, Rabinovitch M, Schermuly R, Stewart D, Truebel H, Walker G, Stenmark KR. Anticipated classes of new medications and molecular targets for pulmonary arterial hypertension. Pulm Circ. 2013 Jan; 3(1):226-44. PMID: 23662201; PMCID: PMC3641734.
      Citations: 23     
    119. Piao L, Sidhu VK, Fang YH, Ryan JJ, Parikh KS, Hong Z, Toth PT, Morrow E, Kutty S, Lopaschuk GD, Archer SL. FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate. J Mol Med (Berl). 2013 Mar; 91(3):333-46. PMID: 23247844; PMCID: PMC3584201.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    120. Piao L, Fang YH, Parikh KS, Ryan JJ, D'Souza KM, Theccanat T, Toth PT, Pogoriler J, Paul J, Blaxall BC, Akhter SA, Archer SL. GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension. Circulation. 2012 Dec 11; 126(24):2859-69. PMID: 23124027; PMCID: PMC4459732.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    121. Rich JD, Archer SL, Rich S. Noninvasive cardiac output measurements in patients with pulmonary hypertension. Eur Respir J. 2013 Jul; 42(1):125-33. PMID: 23100501.
      Citations: 15     Fields:    Translation:Humans
    122. Thenappan T, Ryan JJ, Archer SL. Evolving epidemiology of pulmonary arterial hypertension. Am J Respir Crit Care Med. 2012 Oct 15; 186(8):707-9. PMID: 23071187; PMCID: PMC3480514.
      Citations: 23     Fields:    Translation:Humans
    123. Pogoriler JE, Rich S, Archer SL, Husain AN. Persistence of complex vascular lesions despite prolonged prostacyclin therapy of pulmonary arterial hypertension. Histopathology. 2012 Oct; 61(4):597-609. PMID: 22748137; PMCID: PMC4143476.
      Citations: 16     Fields:    Translation:Humans
    124. Marsboom G, Toth PT, Ryan JJ, Hong Z, Wu X, Fang YH, Thenappan T, Piao L, Zhang HJ, Pogoriler J, Chen Y, Morrow E, Weir EK, Rehman J, Archer SL. Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension. Circ Res. 2012 May 25; 110(11):1484-97. PMID: 22511751; PMCID: PMC3539779.
      Citations: 227     Fields:    Translation:HumansAnimalsCells
    125. Rich JD, Thenappan T, Freed B, Patel AR, Thisted RA, Childers R, Archer SL. QTc prolongation is associated with impaired right ventricular function and predicts mortality in pulmonary hypertension. Int J Cardiol. 2013 Aug 10; 167(3):669-76. PMID: 22459397; PMCID: PMC3389574.
      Citations: 30     Fields:    Translation:Humans
    126. Rehman J, Zhang HJ, Toth PT, Zhang Y, Marsboom G, Hong Z, Salgia R, Husain AN, Wietholt C, Archer SL. Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer. FASEB J. 2012 May; 26(5):2175-86. PMID: 22321727; PMCID: PMC3336787.
      Citations: 281     Fields:    Translation:HumansAnimalsCells
    127. Freed BH, Gomberg-Maitland M, Chandra S, Mor-Avi V, Rich S, Archer SL, Jamison EB, Lang RM, Patel AR. Late gadolinium enhancement cardiovascular magnetic resonance predicts clinical worsening in patients with pulmonary hypertension. J Cardiovasc Magn Reson. 2012 Feb 01; 14:11. PMID: 22296860; PMCID: PMC3311144.
      Citations: 86     Fields:    Translation:Humans
    128. Marsboom G, Wietholt C, Haney CR, Toth PT, Ryan JJ, Morrow E, Thenappan T, Bache-Wiig P, Piao L, Paul J, Chen CT, Archer SL. Lung ¹8F-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring of pulmonary arterial hypertension. Am J Respir Crit Care Med. 2012 Mar 15; 185(6):670-9. PMID: 22246173; PMCID: PMC3326289.
      Citations: 100     Fields:    Translation:Animals
    129. Ryan JJ, Thenappan T, Luo N, Ha T, Patel AR, Rich S, Archer SL. The WHO classification of pulmonary hypertension: A case-based imaging compendium. Pulm Circ. 2012 Jan-Mar; 2(1):107-21. PMID: 22558526; PMCID: PMC3342739.
      Citations: 17     
    130. Ryan JJ, Rich S, Archer SL. Pulmonary endarterectomy surgery--a technically demanding cure for WHO Group IV Pulmonary Hypertension: requirements for centres of excellence and availability in Canada. Can J Cardiol. 2011 Nov-Dec; 27(6):671-4. PMID: 22019277; PMCID: PMC3555483.
      Citations: 4     Fields:    Translation:Humans
    131. Ryan JJ, Kalscheur M, Dellefave L, McNally E, Archer SL. A KCNE1 missense variant (V47I) causing exercise-induced long QT syndrome (Romano Ward). Int J Cardiol. 2012 Apr 19; 156(2):e33-5. PMID: 21907427; PMCID: PMC3253314.
      Citations: 2     Fields:    Translation:Humans
    132. Fang YH, Piao L, Hong Z, Toth PT, Marsboom G, Bache-Wiig P, Rehman J, Archer SL. Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle. J Mol Med (Berl). 2012 Jan; 90(1):31-43. PMID: 21874543; PMCID: PMC3249482.
      Citations: 114     Fields:    Translation:AnimalsCells
    133. Ryan JJ, Rehman J, Archer SL. Paracrine proliferative signaling by senescent cells in world health organization group 3 pulmonary hypertension: age corrupting youth? Circ Res. 2011 Aug 19; 109(5):476-9. PMID: 21852552; PMCID: PMC3178329.
      Citations:    Fields:    Translation:HumansCells
    134. Patel AR, Klein MR, Chandra S, Spencer KT, Decara JM, Lang RM, Burke MC, Garrity ER, Hogarth DK, Archer SL, Sweiss NJ, Beshai JF. Myocardial damage in patients with sarcoidosis and preserved left ventricular systolic function: an observational study. Eur J Heart Fail. 2011 Nov; 13(11):1231-7. PMID: 21810833; PMCID: PMC9275450.
      Citations: 36     Fields:    Translation:Humans
    135. Ryan J, Bloch K, Archer SL. Rodent models of pulmonary hypertension: harmonisation with the world health organisation's categorisation of human PH. Int J Clin Pract Suppl. 2011 Aug; (172):15-34. PMID: 21736677.
      Citations: 37     Fields:    Translation:HumansAnimals
    136. Kim GH, Ryan JJ, Marsboom G, Archer SL. Epigenetic mechanisms of pulmonary hypertension. Pulm Circ. 2011 Jul-Sep; 1(3):347-56. PMID: 22140624; PMCID: PMC3224426.
      Citations: 41     
    137. Luong C, Rey-Perra J, Vadivel A, Gilmour G, Sauve Y, Koonen D, Walker D, Todd KG, Gressens P, Kassiri Z, Nadeem K, Morgan B, Eaton F, Dyck JR, Archer SL, Thébaud B. Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia. Circulation. 2011 May 17; 123(19):2120-31. PMID: 21537000.
      Citations: 51     Fields:    Translation:Animals
    138. Jaff MR, McMurtry MS, Archer SL, Cushman M, Goldenberg N, Goldhaber SZ, Jenkins JS, Kline JA, Michaels AD, Thistlethwaite P, Vedantham S, White RJ, Zierler BK, American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitatio, American Heart Association Council on Peripheral Vascular Disease, American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology. Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association. Circulation. 2011 Apr 26; 123(16):1788-830. PMID: 21422387.
      Citations: 554     Fields:    Translation:Humans
    139. Thenappan T, Goel A, Marsboom G, Fang YH, Toth PT, Zhang HJ, Kajimoto H, Hong Z, Paul J, Wietholt C, Pogoriler J, Piao L, Rehman J, Archer SL. A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion. Am J Respir Crit Care Med. 2011 Apr 15; 183(8):1080-91. PMID: 21148721; PMCID: PMC3086745.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    140. Rich S, Pogoriler J, Husain AN, Toth PT, Gomberg-Maitland M, Archer SL. Long-term effects of epoprostenol on the pulmonary vasculature in idiopathic pulmonary arterial hypertension. Chest. 2010 Nov; 138(5):1234-9. PMID: 21051399; PMCID: PMC2972625.
      Citations: 54     Fields:    Translation:Humans
    141. Erzurum S, Rounds SI, Stevens T, Aldred M, Aliotta J, Archer SL, Asosingh K, Balaban R, Bauer N, Bhattacharya J, Bogaard H, Choudhary G, Dorn GW, Dweik R, Fagan K, Fallon M, Finkel T, Geraci M, Gladwin MT, Hassoun PM, Humbert M, Kaminski N, Kawut SM, Loscalzo J, McDonald D, McMurtry IF, Newman J, Nicolls M, Rabinovitch M, Shizuru J, Oka M, Polgar P, Rodman D, Schumacker P, Stenmark K, Tuder R, Voelkel N, Sullivan E, Weinshilboum R, Yoder MC, Zhao Y, Gail D, Moore TM. Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report. Am J Respir Crit Care Med. 2010 Dec 15; 182(12):1554-62. PMID: 20833821; PMCID: PMC3029941.
      Citations: 46     Fields:    Translation:Humans
    142. Piao L, Marsboom G, Archer SL. Mitochondrial metabolic adaptation in right ventricular hypertrophy and failure. J Mol Med (Berl). 2010 Oct; 88(10):1011-20. PMID: 20820751; PMCID: PMC3031098.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    143. Weir EK, Archer SL. The role of redox changes in oxygen sensing. Respir Physiol Neurobiol. 2010 Dec 31; 174(3):182-91. PMID: 20801237; PMCID: PMC2991626.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    144. Archer SL. The mitochondrion as a Swiss army knife: implications for cardiovascular disease. J Mol Med (Berl). 2010 Oct; 88(10):963-5. PMID: 20711556.
      Citations: 4     Fields:    Translation:Cells
    145. Lin E, Boire A, Hemmige V, Husain AN, Sorrentino M, Nathan S, Akhter SA, Dickstein J, Archer SL. Cardiac tamponade mimicking tuberculous pericarditis as the initial presentation of chronic lymphocytic leukemia in a 58-year-old woman: a case report. J Med Case Rep. 2010 Aug 04; 4:246. PMID: 20684780; PMCID: PMC2923171.
      Citations: 1     Fields:    
    146. Urboniene D, Haber I, Fang YH, Thenappan T, Archer SL. Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2010 Sep; 299(3):L401-12. PMID: 20581101; PMCID: PMC2951068.
      Citations: 84     Fields:    Translation:Animals
    147. Archer SL, Marsboom G, Kim GH, Zhang HJ, Toth PT, Svensson EC, Dyck JR, Gomberg-Maitland M, Husain AN, Cipriani N, Rehman J, Thébaud B. Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target. Circulation. 2010 Jun 22; 121(24):2661-71. PMID: 20529999; PMCID: PMC2914302.
      Citations: 222     Fields:    Translation:HumansAnimalsCells
    148. Nijjar RS, Watson DI, Jamieson GG, Archer S, Bessell JR, Booth M, Cade R, Cullingford GL, Devitt PG, Fletcher DR, Hurley J, Kiroff G, Martin IJ, Nathanson LK, Windsor JA, International Society for the Diseases of the Esophagus-Australasian Section. Five-year follow-up of a multicenter, double-blind randomized clinical trial of laparoscopic Nissen vs anterior 90 degrees partial fundoplication. Arch Surg. 2010 Jun; 145(6):552-7. PMID: 20566975.
      Citations: 19     Fields:    Translation:Humans
    149. Levy DI, Cepaitis E, Wanderling S, Toth PT, Archer SL, Goldstein SA. The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner. J Physiol. 2010 Jul 15; 588(Pt 14):2657-68. PMID: 20498229; PMCID: PMC2916995.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    150. Archer SL, Weir EK, Wilkins MR. Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies. Circulation. 2010 May 11; 121(18):2045-66. PMID: 20458021; PMCID: PMC2869481.
      Citations: 204     Fields:    Translation:HumansAnimals
    151. Sweiss NJ, Hushaw L, Thenappan T, Sawaqed R, Machado RF, Patel AR, Gomberg-Maitland M, Husain AN, Archer SL. Diagnosis and management of pulmonary hypertension in systemic sclerosis. Curr Rheumatol Rep. 2010 Feb; 12(1):8-18. PMID: 20425528; PMCID: PMC2865259.
      Citations: 11     Fields:    Translation:Humans
    152. Rehman J, Archer SL. A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension. Adv Exp Med Biol. 2010; 661:171-85. PMID: 20204730.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    153. Thenappan T, Shah SJ, Rich S, Tian L, Archer SL, Gomberg-Maitland M. Survival in pulmonary arterial hypertension: a reappraisal of the NIH risk stratification equation. Eur Respir J. 2010 May; 35(5):1079-87. PMID: 20032020; PMCID: PMC8782564.
      Citations: 186     Fields:    Translation:Humans
    154. Gomberg-Maitland M, Maitland ML, Barst RJ, Sugeng L, Coslet S, Perrino TJ, Bond L, Lacouture ME, Archer SL, Ratain MJ. A dosing/cross-development study of the multikinase inhibitor sorafenib in patients with pulmonary arterial hypertension. Clin Pharmacol Ther. 2010 Mar; 87(3):303-10. PMID: 20010555; PMCID: PMC3291104.
      Citations: 33     Fields:    Translation:HumansCTClinical Trials
    155. Piao L, Fang YH, Cadete VJ, Wietholt C, Urboniene D, Toth PT, Marsboom G, Zhang HJ, Haber I, Rehman J, Lopaschuk GD, Archer SL. The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle. J Mol Med (Berl). 2010 Jan; 88(1):47-60. PMID: 19949938; PMCID: PMC3155251.
      Citations: 163     Fields:    Translation:HumansAnimals
    156. Bungard TJ, Smigorowsky MJ, Lalonde LD, Hogan T, Doliszny KM, Gebreyesus G, Garg S, Archer SL. Cardiac EASE (Ensuring Access and Speedy Evaluation) - the impact of a single-point-of-entry multidisciplinary outpatient cardiology consultation program on wait times in Canada. Can J Cardiol. 2009 Dec; 25(12):697-702. PMID: 19960130; PMCID: PMC2807832.
      Citations: 10     Fields:    Translation:Humans
    157. Archer SL, Michelakis ED. Phosphodiesterase type 5 inhibitors for pulmonary arterial hypertension. N Engl J Med. 2009 Nov 05; 361(19):1864-71. PMID: 19890129.
      Citations: 66     Fields:    Translation:Humans
    158. Chandra S, Shah SJ, Thenappan T, Archer SL, Rich S, Gomberg-Maitland M. Carbon monoxide diffusing capacity and mortality in pulmonary arterial hypertension. J Heart Lung Transplant. 2010 Feb; 29(2):181-7. PMID: 19783169.
      Citations: 21     Fields:    Translation:Humans
    159. van Haaften T, Byrne R, Bonnet S, Rochefort GY, Akabutu J, Bouchentouf M, Rey-Parra GJ, Galipeau J, Haromy A, Eaton F, Chen M, Hashimoto K, Abley D, Korbutt G, Archer SL, Thébaud B. Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. Am J Respir Crit Care Med. 2009 Dec 01; 180(11):1131-42. PMID: 19713449; PMCID: PMC3269236.
      Citations: 203     Fields:    Translation:AnimalsCells
    160. Morrell NW, Archer SL, Lloyd Jones P, MacLean MR, McMurtry IF, Stenmark KR, Thistlethwaite PA, Weissmann N, Yuan JX, Weir EK, Adnot S, Dupuis J. Cellular and molecular basis of pulmonary arterial hypertension. J Am Coll Cardiol. 2009 Jun 30; 54(1 Suppl):S20-S31. PMID: 19555855; PMCID: PMC2790324.
      Citations: 329     Fields:    Translation:HumansAnimalsCells
    161. Polonsky TS, Taillon LA, Sheth H, Min JK, Archer SL, Ward RP. The association between erectile dysfunction and peripheral arterial disease as determined by screening ankle-brachial index testing. Atherosclerosis. 2009 Dec; 207(2):440-4. PMID: 19501825.
      Citations: 15     Fields:    Translation:HumansPHPublic Health
    162. Shah SJ, Thenappan T, Rich S, Sur J, Archer SL, Gomberg-Maitland M. Value of exercise treadmill testing in the risk stratification of patients with pulmonary hypertension. Circ Heart Fail. 2009 Jul; 2(4):278-86. PMID: 19808350.
      Citations: 13     Fields:    Translation:Humans
    163. McLaughlin VV, Archer SL, Badesch DB, Barst RJ, Farber HW, Lindner JR, Mathier MA, McGoon MD, Park MH, Rosenson RS, Rubin LJ, Tapson VF, Varga J, American College of Cardiology Foundation Task Force on Expert Consensus Documents, American Heart Association, American College of Chest Physicians, American Thoracic Society, Inc, Pulmonary Hypertension Association. ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association. J Am Coll Cardiol. 2009 Apr 28; 53(17):1573-619. PMID: 19389575.
      Citations: 553     Fields:    Translation:HumansPHPublic Health
    164. McLaughlin VV, Archer SL, Badesch DB, Barst RJ, Farber HW, Lindner JR, Mathier MA, McGoon MD, Park MH, Rosenson RS, Rubin LJ, Tapson VF, Varga J, Harrington RA, Anderson JL, Bates ER, Bridges CR, Eisenberg MJ, Ferrari VA, Grines CL, Hlatky MA, Jacobs AK, Kaul S, Lichtenberg RC, Moliterno DJ, Mukherjee D, Pohost GM, Schofield RS, Shubrooks SJ, Stein JH, Tracy CM, Weitz HH, Wesley DJ, ACCF/AHA. ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association. Circulation. 2009 Apr 28; 119(16):2250-94. PMID: 19332472.
      Citations: 366     Fields:    Translation:Humans
    165. Marsboom G, Archer SL. Pathways of proliferation: new targets to inhibit the growth of vascular smooth muscle cells. Circ Res. 2008 Nov 07; 103(10):1047-9. PMID: 18988899; PMCID: PMC2853810.
      Citations: 6     Fields:    Translation:AnimalsCells
    166. Rey-Parra GJ, Archer SL, Bland RD, Albertine KH, Carlton DP, Cho SC, Kirby B, Haromy A, Eaton F, Wu X, Thébaud B. Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease. Am J Respir Crit Care Med. 2008 Aug 15; 178(4):399-406. PMID: 18511704; PMCID: PMC2542441.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    167. Shah SJ, Thenappan T, Rich S, Tian L, Archer SL, Gomberg-Maitland M. Association of serum creatinine with abnormal hemodynamics and mortality in pulmonary arterial hypertension. Circulation. 2008 May 13; 117(19):2475-83. PMID: 18458173.
      Citations: 42     Fields:    Translation:Humans
    168. Archer SL. Dilated cardiomyopathy and left bundle branch block associated with ingestion of colloidal gold and silver is reversed by British antiLewisite and vitamin E: the potential toxicity of metals used as health supplements. Can J Cardiol. 2008 May; 24(5):397-9. PMID: 18464946; PMCID: PMC2643143.
      Citations:    Fields:    Translation:Humans
    169. Wu XC, Kajimoto H, Bonnet S, Hashimoto K, Michelakis ED, Archer SL, Thébaud B. Developmental absence of the O2 sensitivity of L-type calcium channels in preterm ductus arteriosus smooth muscle cells impairs O2 constriction contributing to patent ductus arteriosus. Pediatr Res. 2008 Feb; 63(2):176-81. PMID: 18091358.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    170. Archer SL, Gomberg-Maitland M, Maitland ML, Rich S, Garcia JG, Weir EK. Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer. Am J Physiol Heart Circ Physiol. 2008 Feb; 294(2):H570-8. PMID: 18083891.
      Citations: 188     Fields:    Translation:HumansAnimalsCells
    171. McMurtry MS, Bonnet S, Michelakis ED, Bonnet S, Haromy A, Archer SL. Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study. Am J Physiol Lung Cell Mol Physiol. 2007 Oct; 293(4):L933-40. PMID: 17675370.
      Citations: 35     Fields:    Translation:AnimalsCells
    172. Nagendran J, Archer SL, Soliman D, Gurtu V, Moudgil R, Haromy A, St Aubin C, Webster L, Rebeyka IM, Ross DB, Light PE, Dyck JR, Michelakis ED. Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility. Circulation. 2007 Jul 17; 116(3):238-48. PMID: 17606845.
      Citations: 188     Fields:    Translation:HumansAnimals
    173. Bonnet S, Rochefort G, Sutendra G, Archer SL, Haromy A, Webster L, Hashimoto K, Bonnet SN, Michelakis ED. The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Proc Natl Acad Sci U S A. 2007 Jul 03; 104(27):11418-23. PMID: 17596340; PMCID: PMC1903339.
      Citations: 158     Fields:    Translation:HumansAnimalsCells
    174. Archer SL, Bonnet S. Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension. Pharmacol Ther. 2007 Jul; 115(1):56-69. PMID: 17583356.
      Citations: 40     Fields:    Translation:HumansAnimals
    175. Kajimoto H, Hashimoto K, Bonnet SN, Haromy A, Harry G, Moudgil R, Nakanishi T, Rebeyka I, Michelakis ED, Archer SL, Thébaud B. Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction. Circulation. 2007 Apr 03; 115(13):1777-88. PMID: 17353442.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    176. Archer SL, Allalunis-Turner J, Haromy A, Beaulieu C, Thompson R, Lee CT, Lopaschuk GD, Puttagunta L, Bonnet S, Harry G, Hashimoto K, Porter CJ, Andrade MA, Thebaud B, Michelakis ED, Bonnet S. A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell. 2007 Jan; 11(1):37-51. PMID: 17222789.
      Citations: 670     Fields:    Translation:HumansAnimalsCells
    177. Moudgil R, Michelakis ED, Archer SL. The role of k+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension. Microcirculation. 2006 Dec; 13(8):615-32. PMID: 17085423.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    178. McMurtry MS, Moudgil R, Hashimoto K, Bonnet S, Michelakis ED, Archer SL. Overexpression of human bone morphogenetic protein receptor 2 does not ameliorate monocrotaline pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2007 Apr; 292(4):L872-8. PMID: 17142350.
      Citations: 36     Fields:    Translation:Animals
    179. Weir EK, Archer SL. Counterpoint: Hypoxic pulmonary vasoconstriction is not mediated by increased production of reactive oxygen species. J Appl Physiol (1985). 2006 Sep; 101(3):995-8; discussion 998. PMID: 16902070.
      Citations: 18     Fields:    Translation:HumansAnimals
    180. Archer SL, Michelakis ED. An evidence-based approach to the management of pulmonary arterial hypertension. Curr Opin Cardiol. 2006 Jul; 21(4):385-92. PMID: 16755209.
      Citations: 24     Fields:    Translation:Humans
    181. Stewart DJ, Hilton JD, Arnold JM, Gregoire J, Rivard A, Archer SL, Charbonneau F, Cohen E, Curtis M, Buller CE, Mendelsohn FO, Dib N, Page P, Ducas J, Plante S, Sullivan J, Macko J, Rasmussen C, Kessler PD, Rasmussen HS. Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF(121) (AdVEGF121) versus maximum medical treatment. Gene Ther. 2006 Nov; 13(21):1503-11. PMID: 16791287.
      Citations: 63     Fields:    Translation:HumansCellsCTClinical Trials
    182. Michelakis ED, Porter CJ, Andrade-Navarro MA, Bonnet S, Haromy A, Harry G, Moudgil R, McMurtry MS, Weir EK, Archer SL, Bonnet S, Thébaud B. An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension. Circulation. 2006 Jun 06; 113(22):2630-41. PMID: 16735674.
      Citations: 276     Fields:    Translation:HumansAnimalsCells
    183. Archer SL, Paterson I, Francis GA. Images in cardiovascular medicine. Untreated 37-year-old homozygous familial hypercholesterolemic smoker. Circulation. 2006 May 30; 113(21):e777. PMID: 16735680.
      Citations: 1     Fields:    Translation:Humans
    184. Archer SL, Michelakis ED, Bonnet S, Moudgil R, Wu XC, Weir EK, Thébaud B. A central role for oxygen-sensitive K+ channels and mitochondria in the specialized oxygen-sensing system. Novartis Found Symp. 2006; 272:157-71; discussion 171-5, 214-7. PMID: 16686435.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    185. Weir EK, Buckler KJ, Archer SL, López-Barneo J. Acute oxygen-sensing mechanisms. N Engl J Med. 2005 Nov 10; 353(19):2042-55. PMID: 16282179; PMCID: PMC2803102.
      Citations: 170     Fields:    Translation:HumansCells
    186. Ladha F, Michelakis ED, Sawicka M, Thurston G, Eaton F, Hashimoto K, Harry G, Haromy A, Korbutt G, Archer SL, Thébaud B. Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization. Circulation. 2005 Oct 18; 112(16):2477-86. PMID: 16230500.
      Citations: 208     Fields:    Translation:HumansAnimalsCells
    187. Langleben D, Archer S, Granton J, Hirsch AM, Levy RD, Mehta S, Michelakis E, Stewart DJ, Canadian Cardiovascular Society, Canadian Thoracic Society. Canadian Cardiovascular Society and Canadian Thoracic Society position statement on pulmonary arterial hypertension. Can Respir J. 2005 Sep; 12(6):303-15. PMID: 16247528.
      Citations: 1     Fields:    Translation:Humans
    188. Langleben D, Archer S, Granton J, Hirsch AM, Levy RD, Mehta S, Michelakis E, Stewart DJ, Canadian Cardiovascular Society, Canadian Thoracic Society. Canadian Cardiovascular Society and Canadian Thoracic Society position statement on pulmonary arterial hypertension. Can J Cardiol. 2005 Sep; 21(11):909-14. PMID: 16239973.
      Citations: 1     Fields:    Translation:Humans
    189. Hong Z, Smith AJ, Archer SL, Wu XC, Nelson DP, Peterson D, Johnson G, Weir EK. Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction. Circulation. 2005 Sep 06; 112(10):1494-9. PMID: 16129789.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    190. Archer SL. Pre-B-cell colony-enhancing factor regulates vascular smooth muscle maturation through a NAD+-dependent mechanism: recognition of a new mechanism for cell diversity and redox regulation of vascular tone and remodeling. Circ Res. 2005 Jul 08; 97(1):4-7. PMID: 16002754.
      Citations: 2     Fields:    Translation:HumansCells
    191. McMurtry MS, Archer SL, Altieri DC, Bonnet S, Haromy A, Harry G, Bonnet S, Puttagunta L, Michelakis ED. Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension. J Clin Invest. 2005 Jun; 115(6):1479-91. PMID: 15931388; PMCID: PMC1136986.
      Citations: 146     Fields:    Translation:HumansAnimalsCells
    192. Archer SL, Gragasin FS, Webster L, Bochinski D, Michelakis ED. Aetiology and management of male erectile dysfunction and female sexual dysfunction in patients with cardiovascular disease. Drugs Aging. 2005; 22(10):823-44. PMID: 16245957.
      Citations: 6     Fields:    Translation:Humans
    193. Moudgil R, Michelakis ED, Archer SL. Hypoxic pulmonary vasoconstriction. J Appl Physiol (1985). 2005 Jan; 98(1):390-403. PMID: 15591309.
      Citations: 146     Fields:    Translation:HumansAnimals
    194. Michelakis ED, Weir EK, Archer SL, Thébaud B. Hypoxic pulmonary vasoconstriction: redox regulation of O2-sensitive K+ channels by a mitochondrial O2-sensor in resistance artery smooth muscle cells. J Mol Cell Cardiol. 2004 Dec; 37(6):1119-36. PMID: 15572043.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    195. Archer SL, Greenlund KJ, Valdez R, Casper ML, Rith-Najarian S, Croft JB. Differences in food habits and cardiovascular disease risk factors among Native Americans with and without diabetes: the Inter-Tribal Heart Project. Public Health Nutr. 2004 Dec; 7(8):1025-32. PMID: 15548340.
      Citations: 4     Fields:    Translation:Humans
    196. Michelakis ED, Wu XC, Moudgil R, Kuzyk M, Dyck JR, Harry G, Hashimoto K, Haromy A, Rebeyka I, Archer SL, Thébaud B. Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus. Circulation. 2004 Sep 14; 110(11):1372-9. PMID: 15353504.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    197. Gragasin FS, Michelakis ED, Hogan A, Moudgil R, Hashimoto K, Wu X, Bonnet S, Haromy A, Archer SL. The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BKCa channels. FASEB J. 2004 Sep; 18(12):1382-91. PMID: 15333581.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    198. Archer SL, Wu XC, Nsair A, Bonnet S, Tyrrell B, McMurtry MS, Hashimoto K, Harry G, Michelakis ED, Thébaud B. Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells. Circ Res. 2004 Aug 06; 95(3):308-18. PMID: 15217912.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    199. Newman JH, Fanburg BL, Archer SL, Badesch DB, Barst RJ, Garcia JG, Kao PN, Knowles JA, Loyd JE, McGoon MD, Morse JH, Nichols WC, Rabinovitch M, Rodman DM, Stevens T, Tuder RM, Voelkel NF, Gail DB, National Heart, Lung and Blood Institute/Office of Rare Diseases. Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop. Circulation. 2004 Jun 22; 109(24):2947-52. PMID: 15210611.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    200. Morrell NW, Archer SL, Stenmark KR, MacLean MR, Lang IM, Christman BW, Weir EK, Eickelberg O, Voelkel NF, Rabinovitch M, Humbert M. Cellular and molecular pathobiology of pulmonary arterial hypertension. J Am Coll Cardiol. 2004 Jun 16; 43(12 Suppl S):13S-24S. PMID: 15194174.
      Citations: 501     Fields:    Translation:Humans
    201. Webster LJ, Michelakis ED, Davis T, Archer SL. Use of sildenafil for safe improvement of erectile function and quality of life in men with New York Heart Association classes II and III congestive heart failure: a prospective, placebo-controlled, double-blind crossover trial. Arch Intern Med. 2004 Mar 08; 164(5):514-20. PMID: 15006828.
      Citations: 24     Fields:    Translation:HumansCTClinical Trials
    202. Archer SL, Wu XC, Moudgil R, Hashimoto K, Michelakis ED, Thébaud B. O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide. Biol Chem. 2004 Mar-Apr; 385(3-4):205-16. PMID: 15134333.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    203. Armstrong PW, Ezekowitz C, Michelakis E, Anderson T, Archer S, Ghali W, Hayward R, Jensen L, Lopaschuk G, Sheldon R. Innovative strategic Canadian research training from TomorrOw's Research Cardiovascular Health Care Professionals (TORCH). Clin Invest Med. 2004 Feb; 27(1):33-41. PMID: 15061584.
      Citations: 1     Fields:    Translation:Humans
    204. Michelakis ED, Tymchak W, Noga M, Webster L, Wu XC, Lien D, Wang SH, Modry D, Archer SL. Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension. Circulation. 2003 Oct 28; 108(17):2066-9. PMID: 14568893.
      Citations: 63     Fields:    Translation:HumansCTClinical Trials
    205. Archer SL, Hilner JE, Dyer AR, Greenlund KJ, Colangelo LA, Kiefe CI, Liu K, Coronary Artery Risk Development in Young Adults (CARDIA). Association of education with dietary intake among young adults in the bi-ethnic Coronary Artery Risk Development in Young Adults (CARDIA) cohort. Public Health Nutr. 2003 Oct; 6(7):689-95. PMID: 14552670.
      Citations: 2     Fields:    Translation:Humans
    206. Lara N, Chrapko WE, Archer SL, Mayers I, Bellavance F, Le Mellédo JM. Pulmonary and systemic nitric oxide measurements during CCK-5-induced panic attacks. Neuropsychopharmacology. 2003 Oct; 28(10):1840-5. PMID: 12865901.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    207. Pozeg ZI, Michelakis ED, McMurtry MS, Wu XC, Dyck JR, Hashimoto K, Wang S, Moudgil R, Harry G, Sultanian R, Koshal A, Archer SL, Thébaud B. In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats. Circulation. 2003 Apr 22; 107(15):2037-44. PMID: 12695303.
      Citations: 94     Fields:    Translation:AnimalsCells
    208. Archer SL, Gragasin FS, Wu X, Wang S, McMurtry S, Kim DH, Platonov M, Koshal A, Hashimoto K, Campbell WB, Falck JR, Michelakis ED. Endothelium-derived hyperpolarizing factor in human internal mammary artery is 11,12-epoxyeicosatrienoic acid and causes relaxation by activating smooth muscle BK(Ca) channels. Circulation. 2003 Feb 11; 107(5):769-76. PMID: 12578883.
      Citations: 87     Fields:    Translation:HumansCells
    209. Michelakis ED, McMurtry MS, Sonnenberg B, Archer SL. The NO - K+ channel axis in pulmonary arterial hypertension. Activation by experimental oral therapies. Adv Exp Med Biol. 2003; 543:293-322. PMID: 14713130.
      Citations: 6     Fields:    Translation:HumansAnimals
    210. Michelakis ED, Rebeyka I, Wu X, Nsair A, Hashimoto K, Dyck JR, Haromy A, Harry G, Barr A, Archer SL, Michelakis ED, Rebeyka I, Wu X, Nsair A, Hashimoto K, Dyck JR, Haromy A, Harry G, Barr A, Archer SL. O2 sensing in the human ductus arteriosus: regulation of voltage-gated K+ channels in smooth muscle cells by a mitochondrial redox sensor. Circ Res. 2002 Sep 20; 91(6):478-86. PMID: 12242265.
      Citations: 49     Fields:    Translation:HumansCells
    211. Wu X, Michelakis ED, Hashimoto K, Archer SL, Wu X, Michelakis ED, Hashimoto K, Archer SL. Hypoxic fetoplacental vasoconstriction in humans is mediated by potassium channel inhibition. Am J Physiol Heart Circ Physiol. 2002 Dec; 283(6):H2440-9. PMID: 12388256.
      Citations: 21     Fields:    Translation:Humans
    212. Archer S, Michelakis E. The mechanism(s) of hypoxic pulmonary vasoconstriction: potassium channels, redox O(2) sensors, and controversies. News Physiol Sci. 2002 Aug; 17:131-7. PMID: 12136039.
      Citations: 35     Fields:    Translation:HumansCells
    213. Michelakis E, Wu XC, Harry G, Hashimoto K, Archer SL, Thébaud B. Sildenafil reverses O2 constriction of the rabbit ductus arteriosus by inhibiting type 5 phosphodiesterase and activating BK(Ca) channels. Pediatr Res. 2002 Jul; 52(1):19-24. PMID: 12084842.
      Citations: 14     Fields:    Translation:Animals
    214. Michelakis ED, Hampl V, Nsair A, Wu X, Harry G, Haromy A, Gurtu R, Archer SL. Diversity in mitochondrial function explains differences in vascular oxygen sensing. Circ Res. 2002 Jun 28; 90(12):1307-15. PMID: 12089069.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    215. Michelakis E, Tymchak W, Lien D, Webster L, Hashimoto K, Archer S. Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide. Circulation. 2002 May 21; 105(20):2398-403. PMID: 12021227.
      Citations: 90     Fields:    Translation:HumansCTClinical Trials
    216. Michelakis ED, McMurtry MS, Wu XC, Dyck JR, Moudgil R, Hopkins TA, Lopaschuk GD, Puttagunta L, Waite R, Archer SL. Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels. Circulation. 2002 Jan 15; 105(2):244-50. PMID: 11790708.
      Citations: 155     Fields:    Translation:AnimalsCells
    217. Archer SL, London B, Hampl V, Wu X, Nsair A, Puttagunta L, Hashimoto K, Waite RE, Michelakis ED, Archer SL, London B, Hampl V, Wu X, Nsair A, Puttagunta L, Hashimoto K, Waite RE, Michelakis ED. Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage-gated potassium channel Kv1.5. FASEB J. 2001 Aug; 15(10):1801-3. PMID: 11481235.
      Citations: 35     Fields:    Translation:Animals
    218. Michelakis ED, Weir EK, Wu X, Nsair A, Waite R, Hashimoto K, Puttagunta L, Knaus HG, Archer SL. Potassium channels regulate tone in rat pulmonary veins. Am J Physiol Lung Cell Mol Physiol. 2001 Jun; 280(6):L1138-47. PMID: 11350792.
      Citations: 24     Fields:    Translation:Animals
    219. Reeve HL, Michelakis E, Nelson DP, Weir EK, Archer SL. Alterations in a redox oxygen sensing mechanism in chronic hypoxia. J Appl Physiol (1985). 2001 Jun; 90(6):2249-56. PMID: 11356790.
      Citations: 42     Fields:    Translation:AnimalsCells
    220. Reeve HL, Tolarova S, Nelson DP, Archer S, Weir EK. Redox control of oxygen sensing in the rabbit ductus arteriosus. J Physiol. 2001 May 15; 533(Pt 1):253-61. PMID: 11351032; PMCID: PMC2278616.
      Citations: 16     Fields:    Translation:AnimalsCells
    221. Peterson DA, Reeve HL, Nelson D, Archer SL, Weir EK, Peterson DA, Reeve HL, Nelson D, Archer SL, Weir EK. Triple-bonded unsaturated fatty acids are redox active compounds. Lipids. 2001 Apr; 36(4):431-3. PMID: 11383698.
      Citations:    Fields:    Translation:Cells
    222. Michelakis ED, Dyck JR, McMurtry MS, Wang S, Wu XC, Moudgil R, Hashimoto K, Puttagunta L, Archer SL, Michelakis ED, Dyck JR, McMurtry MS, Wang S, Wu XC, Moudgil R, Hashimoto K, Puttagunta L, Archer SL. Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models. Adv Exp Med Biol. 2001; 502:401-18. PMID: 11950153.
      Citations: 9     Fields:    Translation:HumansAnimals
    223. Archer S, Rich S. Primary pulmonary hypertension: a vascular biology and translational research "Work in progress". Circulation. 2000 Nov 28; 102(22):2781-91. PMID: 11094047.
      Citations: 93     Fields:    Translation:Humans
    224. Michelakis E, Tymchak W, Archer S. Sildenafil: from the bench to the bedside. CMAJ. 2000 Oct 31; 163(9):1171-5. PMID: 11079066; PMCID: PMC80254.
      Citations: 5     Fields:    Translation:Humans
    225. Tanser P, Archer S, Feldman R. Case 2. Recurrence of myocardial infarction. Can J Cardiol. 2000 Aug; 16 Suppl E:24E-26E. PMID: 10906622.
      Citations:    Fields:    Translation:HumansPHPublic Health
    226. Michelakis E, Rebeyka I, Bateson J, Olley P, Puttagunta L, Archer S. Voltage-gated potassium channels in human ductus arteriosus. Lancet. 2000 Jul 08; 356(9224):134-7. PMID: 10963252.
      Citations: 24     Fields:    Translation:HumansCells
    227. Traverse JH, Wang YL, Du R, Nelson D, Lindstrom P, Archer SL, Gong G, Bache RJ. Coronary nitric oxide production in response to exercise and endothelium-dependent agonists. Circulation. 2000 May 30; 101(21):2526-31. PMID: 10831528.
      Citations: 7     Fields:    Translation:Animals
    228. Archer SL. In memoriam : Francis X. Witkowski. Circ Res. 2000 Apr 28; 86(8):823. PMID: 10785500.
      Citations:    Fields:    
    229. Archer SL, Weir EK, Reeve HL, Michelakis E. Molecular identification of O2 sensors and O2-sensitive potassium channels in the pulmonary circulation. Adv Exp Med Biol. 2000; 475:219-40. PMID: 10849663.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    230. Michelakis ED, Weir EK, Nelson DP, Reeve HL, Tolarova S, Archer SL. Dexfenfluramine elevates systemic blood pressure by inhibiting potassium currents in vascular smooth muscle cells. J Pharmacol Exp Ther. 1999 Dec; 291(3):1143-9. PMID: 10565835.
      Citations: 2     Fields:    Translation:AnimalsCells
    231. Cornfield DN, Martin EB, Hampl V, Archer SL. Aerosol delivery of diethylenetriamine/nitric oxide, a nitric oxide adduct, causes selective pulmonary vasodilation in perinatal lambs. J Lab Clin Med. 1999 Oct; 134(4):419-25. PMID: 10521090.
      Citations:    Fields:    Translation:Animals
    232. Reeve HL, Archer SL, Soper M, Weir EK. Dexfenfluramine increases pulmonary artery smooth muscle intracellular Ca2+, independent of membrane potential. Am J Physiol. 1999 09; 277(3):L662-6. PMID: 10484475.
      Citations: 4     Fields:    Translation:AnimalsCells
    233. Tibboel D, Rambaud C, Mercier JC, Bourbon JR, Dinh-Xuan AT, Archer SL, Thébaud B. Vitamin A decreases the incidence and severity of nitrofen-induced congenital diaphragmatic hernia in rats. Am J Physiol. 1999 08; 277(2):L423-9. PMID: 10444537.
      Citations: 32     Fields:    Translation:Animals
    234. Archer SL, Reeve HL, Michelakis E, Puttagunta L, Waite R, Nelson DP, Dinauer MC, Weir EK. O2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase. Proc Natl Acad Sci U S A. 1999 Jul 06; 96(14):7944-9. PMID: 10393927; PMCID: PMC22167.
      Citations: 58     Fields:    Translation:Animals
    235. Reeve HL, Nelson DP, Archer SL, Weir EK. Effects of fluoxetine, phentermine, and venlafaxine on pulmonary arterial pressure and electrophysiology. Am J Physiol. 1999 02; 276(2):L213-9. PMID: 9950882.
      Citations: 4     Fields:    Translation:Animals
    236. Peterson DA, Peterson DC, Reeve HL, Archer SL, Weir EK. GTP (gammaS) and GDP (betaS) as electron donors: new wine in old bottles. Life Sci. 1999; 65(11):1135-40. PMID: 10503929.
      Citations: 1     Fields:    Translation:Cells
    237. Reeve HL, Weir EK, Archer SL, Cornfield DN. A maturational shift in pulmonary K+ channels, from Ca2+ sensitive to voltage dependent. Am J Physiol. 1998 12; 275(6):L1019-25. PMID: 9843837.
      Citations: 12     Fields:    Translation:Animals
    238. Archer SL, Djaballah K, Humbert M, Weir KE, Fartoukh M, Dall'ava-Santucci J, Mercier JC, Simonneau G, Dinh-Xuan AT. Nitric oxide deficiency in fenfluramine- and dexfenfluramine-induced pulmonary hypertension. Am J Respir Crit Care Med. 1998 Oct; 158(4):1061-7. PMID: 9769261.
      Citations: 28     Fields:    Translation:HumansCells
    239. Archer SL, Liu K, Dyer AR, Ruth KJ, Jacobs DR, Van Horn L, Hilner JE, Savage PJ. Relationship between changes in dietary sucrose and high density lipoprotein cholesterol: the CARDIA study. Coronary Artery Risk Development in Young Adults. Ann Epidemiol. 1998 Oct; 8(7):433-8. PMID: 9738689.
      Citations: 5     Fields:    Translation:Humans
    240. Weir EK, Reeve HL, Johnson G, Michelakis ED, Nelson DP, Archer SL. A role for potassium channels in smooth muscle cells and platelets in the etiology of primary pulmonary hypertension. Chest. 1998 Sep; 114(3 Suppl):200S-204S. PMID: 9741569.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    241. Weir EK, Reeve HL, Peterson DA, Michelakis ED, Nelson DP, Archer SL. Pulmonary vasoconstriction, oxygen sensing, and the role of ion channels: Thomas A. Neff lecture. Chest. 1998 Jul; 114(1 Suppl):17S-22S. PMID: 9676606.
      Citations: 5     Fields:    Translation:HumansCells
    242. Archer SL, Green D, Chamberlain M, Dyer AR, Liu K. Association of dietary fish and n-3 fatty acid intake with hemostatic factors in the coronary artery risk development in young adults (CARDIA) study. Arterioscler Thromb Vasc Biol. 1998 Jul; 18(7):1119-23. PMID: 9672072.
      Citations: 15     Fields:    Translation:HumansAnimals
    243. Archer SL, Souil E, Dinh-Xuan AT, Schremmer B, Mercier JC, El Yaagoubi A, Nguyen-Huu L, Reeve HL, Hampl V. Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes. J Clin Invest. 1998 Jun 01; 101(11):2319-30. PMID: 9616203; PMCID: PMC508821.
      Citations: 112     Fields:    Translation:Animals
    244. Tristani-Firouzi M, DeMaster EG, Quast BJ, Nelson DP, Archer SL. Utility of a nitric oxide electrode for monitoring the administration of nitric oxide in biologic systems. J Lab Clin Med. 1998 Mar; 131(3):281-5. PMID: 9523853.
      Citations:    Fields:    Translation:Animals
    245. Michelakis ED, Archer SL. The measurement of NO in biological systems using chemiluminescence. Methods Mol Biol. 1998; 100:111-27. PMID: 10906999.
      Citations: 5     Fields:    Translation:HumansAnimals
    246. Reeve HL, Archer SL, Weir EK. Ion channels in the pulmonary vasculature. Pulm Pharmacol Ther. 1997 Oct-Dec; 10(5-6):243-52. PMID: 9778487.
      Citations: 4     Fields:    Translation:HumansAnimals
    247. Michelakis ED, Reeve HL, Huang JM, Tolarova S, Nelson DP, Weir EK, Archer SL. Potassium channel diversity in vascular smooth muscle cells. Can J Physiol Pharmacol. 1997 Jul; 75(7):889-97. PMID: 9315358.
      Citations: 20     Fields:    Translation:HumansAnimals
    248. Weir EK, Reeve HL, Cornfield DN, Tristani-Firouzi M, Peterson DA, Archer SL. Diversity of response in vascular smooth muscle cells to changes in oxygen tension. Kidney Int. 1997 Feb; 51(2):462-6. PMID: 9027722.
      Citations: 7     Fields:    Translation:AnimalsCells
    249. Tristani-Firouzi M, Martin EB, Tolarova S, Weir EK, Archer SL, Cornfield DN. Ventilation-induced pulmonary vasodilation at birth is modulated by potassium channel activity. Am J Physiol. 1996 Dec; 271(6 Pt 2):H2353-9. PMID: 8997293.
      Citations: 7     Fields:    Translation:Animals
    250. Tristani-Firouzi M, Reeve HL, Tolarova S, Weir EK, Archer SL. Oxygen-induced constriction of rabbit ductus arteriosus occurs via inhibition of a 4-aminopyridine-, voltage-sensitive potassium channel. J Clin Invest. 1996 Nov 01; 98(9):1959-65. PMID: 8903313; PMCID: PMC507638.
      Citations: 25     Fields:    Translation:AnimalsCells
    251. Weir EK, Reeve HL, Huang JM, Michelakis E, Nelson DP, Hampl V, Archer SL. Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction. Circulation. 1996 Nov 01; 94(9):2216-20. PMID: 8901674.
      Citations: 25     Fields:    Translation:Animals
    252. Dillon WC, Hampl V, Shultz PJ, Rubins JB, Archer SL. Origins of breath nitric oxide in humans. Chest. 1996 Oct; 110(4):930-8. PMID: 8874248.
      Citations: 6     Fields:    Translation:Humans
    253. Sidney EJ, Hampl V, Nelson DP, Archer SL, Foegh ML, Cathapermal SS, Weir EK. The somatostatin analog angiopeptin does not reduce chronic hypoxic pulmonary hypertension in rats. Proc Soc Exp Biol Med. 1996 Oct; 213(1):43-9. PMID: 8820822.
      Citations:    Fields:    Translation:Animals
    254. Peterson DA, Peterson DC, Archer SL, Weir EK. Accelerated disulfide reduction with polyunsaturated fatty acids: a mechanism of ionic channel modulation? Redox Rep. 1996 Aug; 2(4):263-5. PMID: 27406276.
      Citations: 1     Fields:    
    255. Cornfield DN, Reeve HL, Tolarova S, Weir EK, Archer S. Oxygen causes fetal pulmonary vasodilation through activation of a calcium-dependent potassium channel. Proc Natl Acad Sci U S A. 1996 Jul 23; 93(15):8089-94. PMID: 8755608; PMCID: PMC38880.
      Citations: 27     Fields:    Translation:Animals
    256. Hampl V, Tristani-Firouzi M, Nelson DP, Archer SL. Chronic infusion of nitric oxide in experimental pulmonary hypertension: pulmonary pressure-flow analysis. Eur Respir J. 1996 Jul; 9(7):1475-81. PMID: 8836662.
      Citations: 2     Fields:    Translation:Animals
    257. Archer SL. Diversity of phenotype and function of vascular smooth muscle cells. J Lab Clin Med. 1996 Jun; 127(6):524-9. PMID: 8648256.
      Citations: 16     Fields:    Translation:Animals
    258. Archer SL, Huang JM, Reeve HL, Hampl V, Michelakis E, Weir EK, Tolarová S. Differential distribution of electrophysiologically distinct myocytes in conduit and resistance arteries determines their response to nitric oxide and hypoxia. Circ Res. 1996 Mar; 78(3):431-42. PMID: 8593702.
      Citations: 65     Fields:    Translation:Animals
    259. Archer SL, Mike D, Crow J, Long W, Weir EK. A placebo-controlled trial of prostacyclin in acute respiratory failure in COPD. Chest. 1996 Mar; 109(3):750-5. PMID: 8617086.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    260. Hampl V, Tristani-Firouzi M, Hutsell TC, Archer SL. Nebulized nitric oxide/nucleophile adduct reduces chronic pulmonary hypertension. Cardiovasc Res. 1996 Jan; 31(1):55-62. PMID: 8849589.
      Citations: 8     Fields:    Translation:Animals
    261. Reeve HL, Weir EK, Nelson DP, Peterson DA, Archer SL. Opposing effects of oxidants and antioxidants on K+ channel activity and tone in rat vascular tissue. Exp Physiol. 1995 Sep; 80(5):825-34. PMID: 8546871.
      Citations: 22     Fields:    Translation:AnimalsCells
    262. Archer SL, Hampl V, Nelson DP, Sidney E, Peterson DA, Weir EK. Dithionite increases radical formation and decreases vasoconstriction in the lung. Evidence that dithionite does not mimic alveolar hypoxia. Circ Res. 1995 Jul; 77(1):174-81. PMID: 7788875.
      Citations: 14     Fields:    Translation:Animals
    263. Archer SL, Freude KA, Shultz PJ. Effect of graded hypoxia on the induction and function of inducible nitric oxide synthase in rat mesangial cells. Circ Res. 1995 Jul; 77(1):21-8. PMID: 7540515.
      Citations: 3     Fields:    Translation:AnimalsCells
    264. Hampl V, Cornfield DN, Cowan NJ, Archer SL. Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells. Eur Respir J. 1995 Apr; 8(4):515-22. PMID: 7664847.
      Citations: 29     Fields:    Translation:AnimalsCells
    265. Weir EK, Archer SL. The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels. FASEB J. 1995 Feb; 9(2):183-9. PMID: 7781921.
      Citations: 86     Fields:    Translation:HumansAnimalsCells
    266. Michelakis ED, Archer SL, Weir EK. Acute hypoxic pulmonary vasoconstriction: a model of oxygen sensing. Physiol Res. 1995; 44(6):361-7. PMID: 8798271.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    267. Lawrence DM, Archer S, Bidlack JM. Identification of opioid receptors in the immune system using a novel combination of selective opioid ligands and indirect phycoerythrin immunofluorescence. Adv Exp Med Biol. 1995; 373:17-21. PMID: 7668148.
      Citations:    Fields:    Translation:AnimalsCells
    268. Hampl V, Huang JM, Weir EK, Archer SL. Activation of the cGMP-dependent protein kinase mimics the stimulatory effect of nitric oxide and cGMP on calcium-gated potassium channels. Physiol Res. 1995; 44(1):39-44. PMID: 8789298.
      Citations: 3     Fields:    Translation:AnimalsCells
    269. Archer SL, Huang JM, Hampl V, Nelson DP, Shultz PJ, Weir EK. Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7583-7. PMID: 7519783; PMCID: PMC44446.
      Citations: 157     Fields:    Translation:Animals
    270. Weir EK, Wyatt CN, Reeve HL, Huang J, Archer SL, Peers C. Diphenyleneiodonium inhibits both potassium and calcium currents in isolated pulmonary artery smooth muscle cells. J Appl Physiol (1985). 1994 Jun; 76(6):2611-5. PMID: 7928890.
      Citations: 21     Fields:    Translation:Animals
    271. Peterson DA, Archer SL, Weir EK. Superoxide reduction of a disulfide: a model of intracellular redox modulation? Biochem Biophys Res Commun. 1994 May 16; 200(3):1586-91. PMID: 8185613.
      Citations: 5     Fields:    Translation:Cells
    272. Isaacson TC, Hampl V, Weir EK, Nelson DP, Archer SL. Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats. J Appl Physiol (1985). 1994 Feb; 76(2):933-40. PMID: 7513687.
      Citations: 19     Fields:    Translation:Animals
    273. Archer SL, Mike DK, Hetland MB, Kostamo KL, Shafer RB, Chesler E. Usefulness of mean aortic valve gradient and left ventricular diastolic filling pattern for distinguishing symptomatic from asymptomatic patients. Am J Cardiol. 1994 Feb 01; 73(4):275-81. PMID: 8296759.
      Citations: 1     Fields:    Translation:Humans
    274. Archer SL, Huang J, Henry T, Peterson D, Weir EK. A redox-based O2 sensor in rat pulmonary vasculature. Circ Res. 1993 Dec; 73(6):1100-12. PMID: 8222081.
      Citations: 96     Fields:    Translation:AnimalsCells
    275. Hampl V, Archer SL, Bach R, Nelson DP, Weir EK. Chronic hypoxic pulmonary hypertension. Is thrombin involved? Am Rev Respir Dis. 1993 Oct; 148(4 Pt 1):1043-8. PMID: 8214923.
      Citations:    Fields:    Translation:Animals
    276. Hampl V, Archer SL, Nelson DP, Weir EK. Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure. J Appl Physiol (1985). 1993 Oct; 75(4):1748-57. PMID: 7506706.
      Citations: 17     Fields:    Translation:Animals
    277. Toher C, Krug H, Archer SL. Diagnosis of pulmonary vein varix by transesophageal echocardiography. Chest. 1993 Jun; 103(6):1901-3. PMID: 8404126.
      Citations: 1     Fields:    Translation:Humans
    278. Peterson DA, Peterson DC, Archer SL, Weir EK. Superoxide dismutase: an antireductant enzyme? Biochem Soc Trans. 1993 May; 21(2):88S. PMID: 8395430.
      Citations: 2     Fields:    Translation:Cells
    279. Henry TD, Archer SL, Nelson D, Weir EK, From AH. Postischemic oxygen radical production varies with duration of ischemia. Am J Physiol. 1993 May; 264(5 Pt 2):H1478-84. PMID: 8498563.
      Citations: 16     Fields:    Translation:Animals
    280. Archer S. Measurement of nitric oxide in biological models. FASEB J. 1993 Feb 01; 7(2):349-60. PMID: 8440411.
      Citations: 128     Fields:    Translation:HumansAnimals
    281. Archer SL, Hampl V. NG-monomethyl-L-arginine causes nitric oxide synthesis in isolated arterial rings: trouble in paradise. Biochem Biophys Res Commun. 1992 Oct 30; 188(2):590-6. PMID: 1445303.
      Citations: 13     Fields:    Translation:Animals
    282. Rice KL, Duane PG, Archer SL, Gilboe DP, Niewoehner DE. H2O2 injury causes Ca(2+)-dependent and -independent hydrolysis of phosphatidylcholine in alveolar epithelial cells. Am J Physiol. 1992 Oct; 263(4 Pt 1):L430-8. PMID: 1415720.
      Citations: 8     Fields:    Translation:AnimalsCells
    283. Peterson DA, Peterson DC, Archer S, Weir EK. The non specificity of specific nitric oxide synthase inhibitors. Biochem Biophys Res Commun. 1992 Sep 16; 187(2):797-801. PMID: 1382421.
      Citations: 19     Fields:    Translation:Cells
    284. Post JM, Hume JR, Archer SL, Weir EK. Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction. Am J Physiol. 1992 Apr; 262(4 Pt 1):C882-90. PMID: 1566816.
      Citations: 101     Fields:    Translation:Animals
    285. Archer SL, Cowan NJ. Measurement of endothelial cytosolic calcium concentration and nitric oxide production reveals discrete mechanisms of endothelium-dependent pulmonary vasodilatation. Circ Res. 1991 Jun; 68(6):1569-81. PMID: 2036711.
      Citations: 7     Fields:    Translation:AnimalsCells
    286. Henry TD, Archer SL, Nelson D, Weir EK, From AH. Enhanced chemiluminescence as a measure of oxygen-derived free radical generation during ischemia and reperfusion. Circ Res. 1990 Dec; 67(6):1453-61. PMID: 2245505.
      Citations: 13     Fields:    Translation:Animals
    287. Archer SL, Rist K, Nelson DP, DeMaster EG, Cowan N, Weir EK. Comparison of the hemodynamic effects of nitric oxide and endothelium-dependent vasodilators in intact lungs. J Appl Physiol (1985). 1990 Feb; 68(2):735-47. PMID: 2156794.
      Citations: 8     Fields:    Translation:Animals
    288. Archer SL, Tolins JP, Raij L, Weir EK. Hypoxic pulmonary vasoconstriction is enhanced by inhibition of the synthesis of an endothelium derived relaxing factor. Biochem Biophys Res Commun. 1989 Nov 15; 164(3):1198-205. PMID: 2480112.
      Citations: 32     Fields:    Translation:Animals
    289. Archer SL, Nelson DP, Weir EK. Simultaneous measurement of O2 radicals and pulmonary vascular reactivity in rat lung. J Appl Physiol (1985). 1989 Nov; 67(5):1903-11. PMID: 2532193.
      Citations: 22     Fields:    Translation:Animals
    290. Archer SL, Nelson DP, Weir EK. Detection of activated O2 species in vitro and in rat lungs by chemiluminescence. J Appl Physiol (1985). 1989 Nov; 67(5):1912-21. PMID: 2532194.
      Citations: 16     Fields:    Translation:Animals
    291. DeMaster EG, Raij L, Archer SL, Weir EK. Hydroxylamine is a vasorelaxant and a possible intermediate in the oxidative conversion of L-arginine to nitric oxide. Biochem Biophys Res Commun. 1989 Aug 30; 163(1):527-33. PMID: 2505770.
      Citations: 19     Fields:    Translation:Animals
    292. Archer SL, Johnson GJ, Gebhard RL, Castleman WL, Levine AS, Westcott JY, Voelkel NF, Nelson DP, Weir EK. Effect of dietary fish oil on lung lipid profile and hypoxic pulmonary hypertension. J Appl Physiol (1985). 1989 Apr; 66(4):1662-73. PMID: 2732158.
      Citations: 7     Fields:    Translation:Animals
    293. Archer SL, Nelson DP, Zimmer S, From AH, Weir EK. Hypoxic pulmonary vasoconstriction is unaltered by creatine depletion induced by dietary beta-guanidino propionic acid. Life Sci. 1989; 45(12):1081-8. PMID: 2796598.
      Citations: 1     Fields:    Translation:Animals
    294. Archer SL, Peterson D, Nelson DP, DeMaster EG, Kelly B, Eaton JW, Weir EK. Oxygen radicals and antioxidant enzymes alter pulmonary vascular reactivity in the rat lung. J Appl Physiol (1985). 1989 Jan; 66(1):102-11. PMID: 2917913.
      Citations: 14     Fields:    Translation:Animals
    295. Weir EK, Archer SL, Edwards JE. Chronic primary and secondary thromboembolic pulmonary hypertension. Chest. 1988 Mar; 93(3 Suppl):149S-154S. PMID: 3277816.
      Citations:    Fields:    Translation:Humans
    296. Archer S, Nelson D, Gebhard R, Levine AS, Prigge W, Weir EK. Effects of dietary fish oil on lung phospholipid fatty acid composition and intrinsic pulmonary vascular reactivity. Cardiovasc Res. 1987 Dec; 21(12):928-32. PMID: 3455359.
      Citations: 1     Fields:    Translation:Animals
    297. Archer S, Gornick C, Grund F, Shafer R, Weir EK. Exercise thallium testing in ventricular preexcitation. Am J Cardiol. 1987 May 01; 59(12):1103-6. PMID: 3578050.
      Citations:    Fields:    Translation:Humans
    298. Archer SL, Chesler E, Cohn JN, Weir EK. ZK 36-374, a stable analog of prostacyclin, prevents acute hypoxic pulmonary hypertension in the dog. J Am Coll Cardiol. 1986 Nov; 8(5):1189-94. PMID: 2428854.
      Citations: 2     Fields:    Translation:Animals
    299. Archer SL, Kulik TJ, Chesler E, Weir EK. The effects of substance P on the preconstricted pulmonary vasculature of the anesthetized dog. Proc Soc Exp Biol Med. 1986 Oct; 183(1):19-27. PMID: 2428048.
      Citations: 3     Fields:    Translation:Animals
    300. Archer SL, Will JA, Weir EK. Redox status in the control of pulmonary vascular tone. Herz. 1986 Jun; 11(3):127-41. PMID: 3017827.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    301. Archer SL, Yankovich RD, Chesler E, Weir EK. Comparative effects of nisoldipine, nifedipine and bepridil on experimental pulmonary hypertension. J Pharmacol Exp Ther. 1985 Apr; 233(1):12-7. PMID: 3872360.
      Citations: 3     Fields:    Translation:Animals
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