 Hemangioma, Cavernous, Central Nervous System
"Hemangioma, Cavernous, Central Nervous System" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A vascular anomaly composed of a collection of large, thin walled tortuous VEINS that can occur in any part of the central nervous system but lack intervening nervous tissue. Familial occurrence is common and has been associated with a number of genes mapped to 7q, 7p and 3q. Clinical features include SEIZURES; HEADACHE; STROKE; and progressive neurological deficit.
| Descriptor ID |
D020786
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| MeSH Number(s) |
C04.557.645.375.385.500 C10.500.190.200 C14.240.850.875.249 C14.907.454.385.500 C15.378.463.515.385.500 C16.131.666.190.200
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| Concept/Terms |
Cerebral Cavernous Hemangioma- Cerebral Cavernous Hemangioma
- Cavernous Hemangioma, Cerebral
- Cavernous Hemangiomas, Cerebral
- Cerebral Cavernous Hemangiomas
- Hemangioma, Cerebral Cavernous
- Hemangiomas, Cerebral Cavernous
Cavernous Hemangioma, Extracerebral- Cavernous Hemangioma, Extracerebral
- Cavernous Hemangiomas, Extracerebral
- Extracerebral Cavernous Hemangioma
- Extracerebral Cavernous Hemangiomas
- Hemangioma, Extracerebral Cavernous
- Hemangiomas, Extracerebral Cavernous
Cavernous Hemangioma, Intracerebral- Cavernous Hemangioma, Intracerebral
- Cavernous Hemangiomas, Intracerebral
- Hemangioma, Intracerebral Cavernous
- Hemangiomas, Intracerebral Cavernous
- Intracerebral Cavernous Hemangioma
- Intracerebral Cavernous Hemangiomas
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Below are MeSH descriptors whose meaning is more general than "Hemangioma, Cavernous, Central Nervous System".
- Diseases [C]
- Neoplasms [C04]
- Neoplasms by Histologic Type [C04.557]
- Neoplasms, Vascular Tissue [C04.557.645]
- Hemangioma [C04.557.645.375]
- Hemangioma, Cavernous [C04.557.645.375.385]
- Hemangioma, Cavernous, Central Nervous System [C04.557.645.375.385.500]
- Nervous System Diseases [C10]
- Nervous System Malformations [C10.500]
- Central Nervous System Vascular Malformations [C10.500.190]
- Hemangioma, Cavernous, Central Nervous System [C10.500.190.200]
- Cardiovascular Diseases [C14]
- Cardiovascular Abnormalities [C14.240]
- Vascular Malformations [C14.240.850]
- Central Nervous System Vascular Malformations [C14.240.850.875]
- Hemangioma, Cavernous, Central Nervous System [C14.240.850.875.249]
- Vascular Diseases [C14.907]
- Hemostatic Disorders [C14.907.454]
- Hemangioma, Cavernous [C14.907.454.385]
- Hemangioma, Cavernous, Central Nervous System [C14.907.454.385.500]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Hemorrhagic Disorders [C15.378.463]
- Hemostatic Disorders [C15.378.463.515]
- Hemangioma, Cavernous [C15.378.463.515.385]
- Hemangioma, Cavernous, Central Nervous System [C15.378.463.515.385.500]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Congenital Abnormalities [C16.131]
- Nervous System Malformations [C16.131.666]
- Central Nervous System Vascular Malformations [C16.131.666.190]
- Hemangioma, Cavernous, Central Nervous System [C16.131.666.190.200]
Below are MeSH descriptors whose meaning is more specific than "Hemangioma, Cavernous, Central Nervous System".
This graph shows the total number of publications written about "Hemangioma, Cavernous, Central Nervous System" by people in this website by year, and whether "Hemangioma, Cavernous, Central Nervous System" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 | | 2004 | 1 | 1 | 2 | | 2005 | 2 | 0 | 2 | | 2006 | 3 | 0 | 3 | | 2007 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2009 | 1 | 1 | 2 | | 2010 | 4 | 1 | 5 | | 2011 | 2 | 0 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 4 | 0 | 4 | | 2015 | 1 | 0 | 1 | | 2016 | 6 | 0 | 6 | | 2017 | 3 | 0 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Hemangioma, Cavernous, Central Nervous System" by people in Profiles.
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Lopez-Ramirez MA, Fonseca G, Zeineddine HA, Girard R, Moore T, Pham A, Cao Y, Shenkar R, de Kreuk BJ, Lagarrigue F, Lawler J, Glass CK, Awad IA, Ginsberg MH. Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations. J Exp Med. 2017 Nov 06; 214(11):3331-3346.
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Girard R, Zeineddine HA, Fam MD, Mayampurath A, Cao Y, Shi C, Shenkar R, Polster SP, Jesselson M, Duggan R, Mikati AG, Christoforidis G, Andrade J, Whitehead KJ, Li DY, Awad IA. Plasma Biomarkers of Inflammation Reflect Seizures and Hemorrhagic Activity of Cerebral Cavernous Malformations. Transl Stroke Res. 2018 02; 9(1):34-43.
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Tang AT, Choi JP, Kotzin JJ, Yang Y, Hong CC, Hobson N, Girard R, Zeineddine HA, Lightle R, Moore T, Cao Y, Shenkar R, Chen M, Mericko P, Yang J, Li L, Tanes C, Kobuley D, Võsa U, Whitehead KJ, Li DY, Franke L, Hart B, Schwaninger M, Henao-Mejia J, Morrison L, Kim H, Awad IA, Zheng X, Kahn ML. Endothelial TLR4 and the microbiome drive cerebral cavernous malformations. Nature. 2017 05 18; 545(7654):305-310.
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Shenkar R, Shi C, Austin C, Moore T, Lightle R, Cao Y, Zhang L, Wu M, Zeineddine HA, Girard R, McDonald DA, Rorrer A, Gallione C, Pytel P, Liao JK, Marchuk DA, Awad IA. RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations. Stroke. 2017 01; 48(1):187-194.
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Girard R, Zeineddine HA, Orsbon C, Tan H, Moore T, Hobson N, Shenkar R, Lightle R, Shi C, Fam MD, Cao Y, Shen L, Neander AI, Rorrer A, Gallione C, Tang AT, Kahn ML, Marchuk DA, Luo ZX, Awad IA. Micro-computed tomography in murine models of cerebral cavernous malformations as a paradigm for brain disease. J Neurosci Methods. 2016 09 15; 271:14-24.
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Shi C, Shenkar R, Zeineddine HA, Girard R, Fam MD, Austin C, Moore T, Lightle R, Zhang L, Wu M, Cao Y, Gunel M, Louvi A, Rorrer A, Gallione C, Marchuk DA, Awad IA. B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models. J Neuroimmune Pharmacol. 2016 06; 11(2):369-77.
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Zhou Z, Tang AT, Wong WY, Bamezai S, Goddard LM, Shenkar R, Zhou S, Yang J, Wright AC, Foley M, Arthur JS, Whitehead KJ, Awad IA, Li DY, Zheng X, Kahn ML. Cerebral cavernous malformations arise from endothelial gain of MEKK3-KLF2/4 signalling. Nature. 2016 Apr 07; 532(7597):122-6.
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Tan H, Zhang L, Mikati AG, Girard R, Khanna O, Fam MD, Liu T, Wang Y, Edelman RR, Christoforidis G, Awad IA. Quantitative Susceptibility Mapping in Cerebral Cavernous Malformations: Clinical Correlations. AJNR Am J Neuroradiol. 2016 Jul; 37(7):1209-15.
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Girard R, Khanna O, Shenkar R, Zhang L, Wu M, Jesselson M, Zeineddine HA, Gangal A, Fam MD, Gibson CC, Whitehead KJ, Li DY, Liao JK, Shi C, Awad IA. Peripheral plasma vitamin D and non-HDL cholesterol reflect the severity of cerebral cavernous malformation disease. Biomark Med. 2016; 10(3):255-64.
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Mikati AG, Khanna O, Zhang L, Girard R, Shenkar R, Guo X, Shah A, Larsson HB, Tan H, Li L, Wishnoff MS, Shi C, Christoforidis GA, Awad IA. Vascular permeability in cerebral cavernous malformations. J Cereb Blood Flow Metab. 2015 Oct; 35(10):1632-9.
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