Wiskott-Aldrich Syndrome Protein Family
"Wiskott-Aldrich Syndrome Protein Family" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.
Descriptor ID |
D051300
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MeSH Number(s) |
D05.750.078.730.912 D12.776.220.525.912
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Wiskott-Aldrich Syndrome Protein Family".
Below are MeSH descriptors whose meaning is more specific than "Wiskott-Aldrich Syndrome Protein Family".
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Below are the most recent publications written about "Wiskott-Aldrich Syndrome Protein Family" by people in Profiles.
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Increased expression levels of WAVE3 are associated with the progression and metastasis of triple negative breast cancer. PLoS One. 2012; 7(8):e42895.